Mechanistic Pathways of Sex Differences in Cardiovascular Disease

Estradiol modulates myosin regulatory light chain phosphorylation and contractility in skeletal muscle of female mice

(2016) Shaojuan Lai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Gender and In-hospital Mortality of ST-Segment Elevation Myocardial Infarction (from a Multihospital Nationwide Registry Study of 31,689 Patients)

(2015) Ville Kytö et al.   AMERICAN JOURNAL OF CARDIOLOGY

Does cellular sex matter? Dimorphic transcriptional differences between female and male endothelial cells

(2015) Mario Lorenz et al.   ATHEROSCLEROSIS

Antiandrogenic Therapy With Finasteride Attenuates Cardiac Hypertrophy and Left Ventricular Dysfunction

(2015) C. Zwadlo et al.   CIRCULATION

Sudden Cardiac Arrest During Sports Activity in Middle Age

(2015) E. Marijon et al.   CIRCULATION

Cardiomyocyte-specific overexpression of oestrogen receptor   improves survival and cardiac function after myocardial infarction in female and male mice

(2015) I. Schuster et al.   CLINICAL SCIENCE

Sex differences in clinical characteristics and outcomes after myocardial infarction: insights from the Valsartan in Acute Myocardial Infarction Trial (VALIANT)

(2015) Carolyn S. P. Lam et al.   EUROPEAN JOURNAL OF HEART FAILURE

Females have a blunted cardiovascular response to one year of intensive supervised endurance training

(2015) Erin J. Howden et al.   JOURNAL OF APPLIED PHYSIOLOGY

Significant role of estrogen in maintaining cardiac mitochondrial functions

(2015) Chutima Rattanasopa et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy

(2015) Christian Templin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Opinion: Focus on preclinical sex differences will not address women’s and men’s health disparities

(2015) Sarah S. Richardson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of aging on cardiac extracellular matrix in men and women

(2015) Elke Dworatzek et al.   Proteomics Clinical Applications

A Composite Measure of Gender and Its Association With Risk Factors in Patients With Premature Acute Coronary Syndrome

(2015) Roxanne Pelletier et al.   PSYCHOSOMATIC MEDICINE

Implantable Cardioverter-Defibrillator Therapy in Patients With Ventricular Fibrillation out of Hospital Cardiac Arrest Secondary to Acute Coronary Syndrome

(2015) M. Madhavan et al.   Journal of the American Heart Association

Exogenous 17-β estradiol administration blunts progression of established angiotensin II-induced abdominal aortic aneurysms in female ovariectomized mice

(2015) Sean E. Thatcher et al.   Biology of Sex Differences

Cardiac contraction, calcium transients, and myofilament calcium sensitivity fluctuate with the estrous cycle in young adult female mice

(2014) Jennifer K. MacDonald et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sex differences in the mechanisms underlying long QT syndrome

(2014) Guy Salama et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Coronary artery disease predisposing haplogroup I of the Y chromosome, aggression and sex steroids – Genetic association analysis

(2014) Lisa D.S. Bloomer et al.   ATHEROSCLEROSIS

Impact of isolated systolic hypertension on normalization of left ventricular structure during antihypertensive treatment (the LIFE study)

(2014) Costantino Mancusi et al.   BLOOD PRESSURE

The number of X chromosomes influences protection from cardiac ischaemia/reperfusion injury in mice: one X is better than two

(2014) J. Li et al.   CARDIOVASCULAR RESEARCH

P68ERbeta prevents up-regulation of miRNAs under pressure overload in LV of female mice

(2014) H Sanchez Ruderisch et al.   CARDIOVASCULAR RESEARCH

Sex differences in exercise-induced physiological myocardial hypertrophy are modulated by oestrogen receptor beta

(2014) Elke Dworatzek et al.   CARDIOVASCULAR RESEARCH

Epidemiology and Clinical Profile of Takotsubo Cardiomyopathy

(2014) Scott W. Sharkey et al.   CIRCULATION JOURNAL

Interstitial Fibrosis, Left Ventricular Remodeling, and Myocardial Mechanical Behavior in a Population-Based Multiethnic Cohort

(2014) Sirisha Donekal et al.   Circulation-Cardiovascular Imaging

Spontaneous Coronary Artery Dissection

(2014) Jacqueline Saw et al.   Circulation-Cardiovascular Interventions

Genetic Background Defines the Regulation of Postnatal Cardiac Growth by 17β-Estradiol Through a β-Catenin Mechanism

(2014) Georgios Kararigas et al.   ENDOCRINOLOGY

Sex-specific cardiovascular structure and function in heart failure with preserved ejection fraction

(2014) Mauro Gori et al.   EUROPEAN JOURNAL OF HEART FAILURE

Sex-dependent regulation of fibrosis and inflammation in human left ventricular remodelling under pressure overload

(2014) Georgios Kararigas et al.   EUROPEAN JOURNAL OF HEART FAILURE

Sex differences in cardiovascular outcome during progression of aortic valve stenosis

(2014) Dana Cramariuc et al.   HEART

Sex differences in SR Ca2+ release in murine ventricular myocytes are regulated by the cAMP/PKA pathway

(2014) Randi J. Parks et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MicroRNA-23a mediates mitochondrial compromise in estrogen deficiency-induced concentric remodeling via targeting PGC-1α

(2014) Lu-Yao Sun et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Comparative Proteomic Analysis Reveals Sex and Estrogen Receptor β Effects in the Pressure Overloaded Heart

(2014) Georgios Kararigas et al.   JOURNAL OF PROTEOME RESEARCH

Noncardiac Comorbidities in Heart Failure With Reduced Versus Preserved Ejection Fraction

(2014) Robert J. Mentz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Female mice liberated for inclusion in neuroscience and biomedical research

(2014) Brian J. Prendergast et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Mitochondrial p38β and Manganese Superoxide Dismutase Interaction Mediated by Estrogen in Cardiomyocytes

(2014) Han Liu et al.   PLoS One

Association of the Common Genetic Polymorphisms and Haplotypes of the Chymase Gene with Left Ventricular Mass in Male Patients with Symptomatic Aortic Stenosis

(2014) Ewa Orlowska-Baranowska et al.   PLoS One

Burden of Hospital Admission and Repeat Angiography in Angina Pectoris Patients with and without Coronary Artery Disease: A Registry-Based Cohort Study

(2014) Lasse Jespersen et al.   PLoS One

Maladaptive Remodeling Is Associated With Impaired Survival in Women But Not in Men After Aortic Valve Replacement

(2014) George Petrov et al.   JACC-Cardiovascular Imaging

Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation

(2014) Taru Tukiainen et al.   PLoS Genetics

Trends in the Clinical and Pathological Characteristics of Cardiac Rupture in Patients With Acute Myocardial Infarction Over 35 Years

(2014) Satoshi Honda et al.   Journal of the American Heart Association

Sex-biased chromatin and regulatory cross-talk between sex chromosomes, autosomes, and mitochondria

(2014) Katherine Silkaitis et al.   Biology of Sex Differences

Musculoskeletal and prostate effects of combined testosterone and finasteride administration in older hypogonadal men: a randomized, controlled trial

(2013) Stephen E. Borst et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

LXR agonism improves TNF-α-induced endothelial dysfunction in the absence of its cholesterol-modulating effects

(2013) Frank Spillmann et al.   ATHEROSCLEROSIS

Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study

(2013) Kira C Taylor et al.   BMC GENETICS

Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction

(2013) Bernhard Unsöld et al.   CARDIOVASCULAR RESEARCH

Genetic variation and gender determine bradykinin type 1 receptor responses in human tissue: implications for the ACE-inhibitor-induced effects in patients with coronary artery disease

(2013) Haiyan Wu et al.   CLINICAL SCIENCE

The AF-1 Activation Function of Estrogen Receptor α Is Necessary and Sufficient for Uterine Epithelial Cell Proliferation In Vivo

(2013) Anne Abot et al.   ENDOCRINOLOGY

Role of Androgens in Sex Differences in Cardiac Damage During Myocardial Infarction

(2013) Thi Y. L. Le et al.   ENDOCRINOLOGY

Estrogen: A master regulator of bioenergetic systems in the brain and body

(2013) Jamaica R. Rettberg et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Sex- and estrogen-dependent regulation of a miRNA network in the healthy and hypertrophied heart

(2013) Ana Maria Queirós et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Membrane ERα attenuates myocardial fibrosis via RhoA/ROCK-mediated actin remodeling in ovariectomized female infarcted rats

(2013) Tsung-Ming Lee et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Apoptosis and autophagy contribute to gender difference in cardiac ischemia–reperfusion induced injury in rats

(2013) Chen Chen et al.   LIFE SCIENCES

Protein oxidation seems to be linked to constitutive autophagy: A sex study

(2013) Ilaria Campesi et al.   LIFE SCIENCES

Endothelin-1 overexpression and endothelial nitric oxide synthase knock-out induce different pathological responses in the heart of male and female mice

(2013) Nicolas Vignon-Zellweger et al.   LIFE SCIENCES

Estrogen modulates cardiac growth through an estrogen receptor α-dependent mechanism in healthy ovariectomized mice

(2013) Georgios Kararigas et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Visualising Androgen Receptor Activity in Male and Female Mice

(2013) D. Alwyn Dart et al.   PLoS One

CYP2J2 Overexpression Protects against Arrhythmia Susceptibility in Cardiac Hypertrophy

(2013) Christina Westphal et al.   PLoS One

Sex Differences in the Beneficial Cardiac Effects of Chronic Treatment with Atrial Natriuretic Peptide In Spontaneously Hypertensive Rats

(2013) Mariana Romero et al.   PLoS One

Mutation of the palmitoylation site of estrogen receptor   in vivo reveals tissue-specific roles for membrane versus nuclear actions

(2013) M. Adlanmerini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reproductive hormone concentrations in pregnancy and neonates: a systematic review

(2013) E.A.M. Kuijper et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Testosterone and the Cardiovascular System: A Comprehensive Review of the Clinical Literature

(2013) Peyman Mesbah Oskui et al.   Journal of the American Heart Association

Tissue-specific sex differences in docosahexaenoic acid and Δ6-desaturase in rats fed a standard chow diet

(2012) Alex P. Kitson et al.   Applied Physiology Nutrition and Metabolism

Genetic background, gender, age, body temperature, and arterial blood pH have a major impact on myocardial infarct size in the mouse and need to be carefully measured and/or taken into account: results of a comprehensive analysis of determinants of infarct size in 1,074 mice

(2012) Yiru Guo et al.   BASIC RESEARCH IN CARDIOLOGY

CardioNet: A human metabolic network suited for the study of cardiomyocyte metabolism

(2012) Anja Karlstädt et al.   BMC Systems Biology

17β-Estradiol-induced interaction of ERα with NPPA regulates gene expression in cardiomyocytes

(2012) Shokoufeh Mahmoodzadeh et al.   CARDIOVASCULAR RESEARCH

Clinical Features, Management, and Prognosis of Spontaneous Coronary Artery Dissection

(2012) Marysia S. Tweet et al.   CIRCULATION

Cytochrome P450 Subfamily 2J Polypeptide 2 Expression and Circulating Epoxyeicosatrienoic Metabolites in Preeclampsia

(2012) Florian Herse et al.   CIRCULATION

Third Universal Definition of Myocardial Infarction

(2012) Kristian Thygesen et al.   CIRCULATION

Sex Differences in Clinical Characteristics and Outcomes in Elderly Patients With Heart Failure and Preserved Ejection Fraction

(2012) Carolyn S.P. Lam et al.   Circulation-Heart Failure

Testosterone Supplementation in Heart Failure

(2012) Mustafa Toma et al.   Circulation-Heart Failure

Females Live Longer than Males: Role of Oxidative Stress

(2012) Jose Vina et al.   CURRENT PHARMACEUTICAL DESIGN

Estrogens Mediate Cardiac Hypertrophy in a Stimulus-Dependent Manner

(2012) Christopher D. Haines et al.   ENDOCRINOLOGY

Gender and survival in patients with heart failure: interactions with diabetes and aetiology. Results from the MAGGIC individual patient meta-analysis†

(2012) Manuel Martínez-Sellés et al.   EUROPEAN JOURNAL OF HEART FAILURE

Estradiol enhances effects of fructose rich diet on cardiac fatty acid transporter CD36 and triglycerides accumulation

(2012) Goran Korićanac et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dose-dependent effects of a genistein-enriched diet in the heart of ovariectomized mice

(2012) Ba Tiep Nguyen et al.   Genes and Nutrition

Sex and Sex Hormone–Dependent Cardiovascular Stress Responses

(2012) Vera Regitz-Zagrosek et al.   HYPERTENSION

542 542 CHARACTERISATION OF THE PRESSURE DEPENDENCY OF PULSE WAVE VELOCITY IN THE MOUSE AORTA

(2012) Kayla Viegas et al.   JOURNAL OF HYPERTENSION

Estrogen improves vascular function via peroxisome-proliferator-activated-receptor-γ

(2012) Vedat Tiyerili et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Transcriptome Characterization of Estrogen-Treated Human Myocardium Identifies Myosin Regulatory Light Chain Interacting Protein as a Sex-Specific Element Influencing Contractile Function

(2012) Georgios Kararigas et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inheritance of coronary artery disease in men: an analysis of the role of the Y chromosome

(2012) Fadi J Charchar et al.   LANCET

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Androgens Contribute to Sex Differences in Myocardial Remodeling under Pressure Overload by a Mechanism Involving TGF-β

(2012) Cecilia Montalvo et al.   PLoS One

Effects of Estrogen, an ERα Agonist and Raloxifene on Pressure Overload Induced Cardiac Hypertrophy

(2012) Christina Westphal et al.   PLoS One

4-vinylcyclohexene diepoxide: a model chemical for ovotoxicity

(2012) Connie J. Kappeler et al.   Systems Biology in Reproductive Medicine

Role of 5α-Reductase Inhibitors in Prostate Cancer Prevention and Treatment

(2012) Faris Azzouni et al.   UROLOGY

Sex-Steroid Hormones and Electrocardiographic QT-Interval Duration: Findings From the Third National Health and Nutrition Examination Survey and the Multi-Ethnic Study of Atherosclerosis

(2011) Yiyi Zhang et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability

(2011) Anna Foryst-Ludwig et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Prenatal Famine and Adult Health

(2011) L.H. Lumey et al.   Annual Review of Public Health

Sex-dimorphism in Cardiac Nutrigenomics: effect of Trans fat and/or Monosodium Glutamate consumption

(2011) Kate S Collison et al.   BMC GENOMICS

ESR1 in myocardial infarction

(2011) Monika Puzianowska-Kuźnicka   CLINICA CHIMICA ACTA

The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders

(2011) Walter L. Miller et al.   ENDOCRINE REVIEWS

Aromatase Deficiency Confers Paradoxical Postischemic Cardioprotection

(2011) James R. Bell et al.   ENDOCRINOLOGY

ESC Guidelines on the management of cardiovascular diseases during pregnancy: The Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC)

(2011) et al.   EUROPEAN HEART JOURNAL

Interaction Between Insulin and Estradiol in Regulation of Cardiac Glucose and Free Fatty Acid Transporters

(2011) S. Tepavcevic et al.   HORMONE AND METABOLIC RESEARCH

Sex differences in disease risk from reported genome-wide association study findings

(2011) Linda Y. Liu et al.   HUMAN GENETICS

Estrogen Receptor-β Signals Left Ventricular Hypertrophy Sex Differences in Normotensive Deoxycorticosterone Acetate-Salt Mice

(2011) Dennis Gürgen et al.   HYPERTENSION

Non-nuclear Estrogen Receptor Signaling in the Endothelium

(2011) Qian Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Update in Hyper- and Hypogonadotropic Amenorrhea

(2011) Nanette Santoro   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ovariectomy enhances SR Ca2+ release and increases Ca2+ spark amplitudes in isolated ventricular myocytes

(2011) Elias Fares et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Selective Oestrogen Receptor Modulators Differentially Potentiate Brain Mitochondrial Function

(2011) R. W. Irwin et al.   JOURNAL OF NEUROENDOCRINOLOGY

Early Prenatal Stress Epigenetically Programs Dysmasculinization in Second-Generation Offspring via the Paternal Lineage

(2011) C. P. Morgan et al.   JOURNAL OF NEUROSCIENCE

Environmentally induced epigenetic transgenerational inheritance of phenotype and disease

(2011) Carlos Guerrero-Bosagna et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Role of the estrogen/estrogen-receptor-beta axis in the genomic response to pressure overload-induced hypertrophy

(2011) Georgios Kararigas et al.   PHYSIOLOGICAL GENOMICS

Long-Term Treatment of Ovariectomized Mice with Estradiol or Phytoestrogens as a New Model to Study the Role of Estrogenic Substances in the Heart

(2011) Ba Nguyen et al.   PLANTA MEDICA

Reduced Bone Mass and Muscle Strength in Male 5α-Reductase Type 1 Inactivated Mice

(2011) Sara H. Windahl et al.   PLoS One

Estrogen receptor   AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators

(2011) Y. Arao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary phytoestrogen supplementation induces sex differences in the myocardial protein pattern of mice: A comparative proteomics study

(2011) Karima Schwab et al.   PROTEOMICS

Tissue physiology and pathology of aromatase

(2011) Carlos Stocco   STEROIDS

Sex chromosome complement contributes to sex differences in coxsackievirus B3 but not influenza A virus pathogenesis

(2011) Dionne P Robinson et al.   Biology of Sex Differences

Sex-related resistance to myocardial ischemia-reperfusion injury is associated with high constitutive ARC expression

(2010) Wobbe Bouma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Do androgens play a beneficial role in the regulation of vascular tone? Nongenomic vascular effects of testosterone metabolites

(2010) Mercedes Perusquía et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiac-specific overexpression of dominant-negative CREB leads to increased mortality and mitochondrial dysfunction in female mice

(2010) Peter A. Watson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Endothelium-dependent relaxation by G protein-coupled receptor 30 agonists in rat carotid arteries

(2010) Brad R. S. Broughton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Female sex and estrogen receptor-β attenuate cardiac remodeling and apoptosis in pressure overload

(2010) Daniela Fliegner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Endothelial Estrogen Receptor α Plays an Essential Role in the Coronary and Myocardial Protective Effects of Estradiol in Ischemia/Reperfusion

(2010) Julie Favre et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Testosterone affects hormone-sensitive lipase (HSL) activity and lipid metabolism in the left ventricle

(2010) Jozef Langfort et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

eNOS phosphorylation and translocation are altered in male but not female mice by increased activation of the Gαq protein

(2010) C. Ruiz-Holst et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Oestrogen prevents cardiomyocyte apoptosis by suppressing p38α-mediated activation of p53 and by down-regulating p53 inhibition on p38β

(2010) Han Liu et al.   CARDIOVASCULAR RESEARCH

Differential Cardiac Remodeling in Preload Versus Afterload

(2010) Karl Toischer et al.   CIRCULATION

Regression of Myocardial Hypertrophy After Aortic Valve Replacement: Faster in Women?

(2010) G. Petrov et al.   CIRCULATION

Protective Effects of Estrogen Against Reperfusion Arrhythmias Following Severe Myocardial Ischemia in Rats

(2010) Yan Wang et al.   CIRCULATION JOURNAL

Sex Differences in the Phosphorylation of Mitochondrial Proteins Result in Reduced Production of Reactive Oxygen Species and Cardioprotection in Females

(2010) Claudia J. Lagranha et al.   CIRCULATION RESEARCH

Long-Term Anabolic-Androgenic Steroid Use Is Associated With Left Ventricular Dysfunction

(2010) Aaron L. Baggish et al.   Circulation-Heart Failure

Effect of Estradiol-17β on protein synthesis and degradation rates in fused bovine satellite cell cultures

(2010) E. Kamanga-Sollo et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Epigenetic organization of brain sex differences and juvenile social play behavior

(2010) Anthony P. Auger et al.   HORMONES AND BEHAVIOR

An association between gene expression and better survival in female mice following myocardial infarction

(2010) Quanhai Chen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Testosterone-Down-Regulated Akt Pathway During Cardiac Ischemia/Reperfusion: A Mechanism Involving BAD, Bcl-2 and FOXO3a

(2010) Chunyan Huang et al.   JOURNAL OF SURGICAL RESEARCH

17beta-estradiol attenuates pressure overload-induced myocardial hypertrophy through regulating caveolin-3 protein in ovariectomized female rats

(2010) Yu-Hong Cui et al.   MOLECULAR BIOLOGY REPORTS

Androgen Receptor Counteracts Doxorubicin-Induced Cardiotoxicity in Male Mice

(2010) Yasumasa Ikeda et al.   MOLECULAR ENDOCRINOLOGY

Endothelial regulation of eNOS, PAI-1 and t-PA by testosterone and dihydrotestosterone in vitro and in vivo

(2010) L. Goglia et al.   MOLECULAR HUMAN REPRODUCTION

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

(2010) Daniel Schramek et al.   NATURE

Hormonal modulation of endothelial NO production

(2010) Sue P. Duckles et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Men supplemented with 17β-estradiol have increased β-oxidation capacity in skeletal muscle

(2010) Amy C. Maher et al.   PHYSIOLOGICAL GENOMICS

Testosterone Physiology in Resistance Exercise and Training

(2010) Jakob L. Vingren et al.   SPORTS MEDICINE

Heavy resistance exercise training and skeletal muscle androgen receptor expression in younger and older men

(2010) Juha P. Ahtiainen et al.   STEROIDS

Sex-specific modification of progesterone receptor expression by 17β-oestradiol in human cardiac tissues

(2010) Georgios Kararigas et al.   Biology of Sex Differences

X Chromosomal Variation Is Associated with Slow Progression to AIDS in HIV-1-Infected Women

(2009) Roman A. Siddiqui et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats

(2009) Anne M. Deschamps et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Epigenetics and the Environmental Regulation of the Genome and Its Function

(2009) Tie-Yuan Zhang et al.   Annual Review of Psychology

Gender differences in apoptotic signaling in heart failure due to volume overload

(2009) Melissa R. Dent et al.   APOPTOSIS

Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications

(2009) Jin-Qiang Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Oestrogen confers cardioprotection by suppressing Ca2+/calmodulin-dependent protein kinase II

(2009) Y Ma et al.   BRITISH JOURNAL OF PHARMACOLOGY

17β-Estradiol inhibits matrix metalloproteinase-2 transcription via MAP kinase in fibroblasts

(2009) Shokoufeh Mahmoodzadeh et al.   CARDIOVASCULAR RESEARCH

Estrogen Receptor-β Activation Results in S-Nitrosylation of Proteins Involved in Cardioprotection

(2009) Jeffrey Lin et al.   CIRCULATION

Regulatory Role of G Protein–Coupled Estrogen Receptor for Vascular Function and Obesity

(2009) Elvira Haas et al.   CIRCULATION RESEARCH

G Protein-Coupled Receptor 30: Estrogen Receptor or Collaborator?

(2009) Ellis R. Levin   ENDOCRINOLOGY

Rapid Estrogen Receptor-α Activation Improves Ischemic Tolerance in Aged Female Rats through a Novel Protein Kinase Cε-Dependent Mechanism

(2009) Jennifer L. Novotny et al.   ENDOCRINOLOGY

The gene expression profile of patients with new-onset heart failure reveals important gender-specific differences

(2009) B. Heidecker et al.   EUROPEAN HEART JOURNAL

Cell sex determines anoikis resistance in vascular smooth muscle cells

(2009) Elisabetta Straface et al.   FEBS LETTERS

The organizational–activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues

(2009) Arthur P. Arnold   HORMONES AND BEHAVIOR

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

Circulating Estradiol and Mortality in Men With Systolic Chronic Heart Failure

(2009) Ewa A. Jankowska   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sex Differences in Mortality Following Acute Coronary Syndromes

(2009) Jeffrey S. Berger   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sexual Autophagic Differences in the Androgen-Dependent Flank Organ of Syrian Hamsters

(2009) A. Coto-Montes et al.   JOURNAL OF ANDROLOGY

Nuclear Factor-κB Regulates Estrogen Receptor-α Transcription in the Human Heart

(2009) Shokoufeh Mahmoodzadeh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gender differences of echocardiographic and gene expression patterns in human pressure overload left ventricular hypertrophy

(2009) Ana V. Villar et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Central control of fever and female body temperature by RANKL/RANK

(2009) Reiko Hanada et al.   NATURE

Gender differences in the cardiovascular effect of sex hormones

(2009) Cristiana Vitale et al.   Nature Reviews Cardiology

The transactivating function 1 of estrogen receptor α is dispensable for the vasculoprotective actions of 17β-estradiol

(2009) Audrey Billon-Galés et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Acute postischemic treatment with estrogen receptor-α agonist or estrogen receptor-β agonist improves myocardial recovery

(2009) Nicholas D. Vornehm et al.   SURGERY

Cardiovascular Risk in Women With Non-Specific Chest Pain (from the Women's Health Initiative Hormone Trials) † ‡

(2008) Jennifer G. Robinson et al.   AMERICAN JOURNAL OF CARDIOLOGY

Regulation of Estrogenic Effects by Beclin 1 in Breast Cancer Cells

(2008) S. John et al.   CANCER RESEARCH

Estrogen Attenuates Left Ventricular and Cardiomyocyte Hypertrophy by an Estrogen Receptor–Dependent Pathway That Increases Calcineurin Degradation

(2008) Cameron Donaldson et al.   CIRCULATION RESEARCH

Sex and Age Dimorphism of Myocardial Gene Expression in Nonischemic Human Heart Failure

(2008) David R. Fermin et al.   Circulation-Cardiovascular Genetics

G Protein-Coupled Receptor 30 Localizes to the Endoplasmic Reticulum and Is Not Activated by Estradiol

(2008) Christiane Otto et al.   ENDOCRINOLOGY

Expression Pattern of G Protein-Coupled Receptor 30 in LacZ Reporter Mice

(2008) Jörg Isensee et al.   ENDOCRINOLOGY

Redox state and gender differences in vascular smooth muscle cells

(2008) Walter Malorni et al.   FEBS LETTERS

Genome-wide histone methylation profile for heart failure

(2008) Ruri Kaneda et al.   GENES TO CELLS

Deoxycorticosterone Acetate-Salt Mice Exhibit Blood Pressure–Independent Sexual Dimorphism

(2008) Aysun Karatas et al.   HYPERTENSION

Gender Differences in Left Ventricular Structure and Function During Antihypertensive Treatment

(2008) Eva Gerdts et al.   HYPERTENSION

Starving Neurons Show Sex Difference in Autophagy

(2008) Lina Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

17 Beta-Estradiol Differentially Affects Left Ventricular and Cardiomyocyte Hypertrophy Following Myocardial Infarction and Pressure Overload

(2008) Richard D. Patten et al.   JOURNAL OF CARDIAC FAILURE

Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)α agonist and unaffected by an ERβ antagonist

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