Insights into the control of RAD51 nucleoprotein filament dynamics from single-molecule studies

Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins

(2021) Ondrej Belan et al.   MOLECULAR CELL

The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination

(2021) Upasana Roy et al.   MOLECULAR CELL

RADX controls RAD51 filament dynamics to regulate replication fork stability

(2021) Madison B. Adolph et al.   MOLECULAR CELL

Single-molecule studies illuminate the function of RAD51 paralogs

(2021) Petr Cejka   MOLECULAR CELL

Super-resolution mapping of cellular double-strand break resection complexes during homologous recombination

(2021) Donna R. Whelan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single molecule microscopy reveals key physical features of repair foci in living cells

(2021) Judith Miné-Hattab et al.   eLife

Distinct pathways of homologous recombination controlled by the SWS1–SWSAP1–SPIDR complex

(2021) Rohit Prakash et al.   Nature Communications

Role of BRCA2 DNA-binding and C-terminal domain in its mobility and conformation in DNA repair

(2021) Maarten W Paul et al.   eLife

The Regulation of Homologous Recombination by Helicases

(2020) Eric Huselid et al.   Genes

RAD51 Gene Family Structure and Function

(2020) Braulio Bonilla et al.   Annual Review of Genetics

Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination

(2020) J. Brooks Crickard et al.   CELL

Rad54 and Rdh54 occupy spatially and functionally distinct sites within the Rad51‐ss DNA presynaptic complex

(2020) J Brooks Crickard et al.   EMBO JOURNAL

RADX condenses single-stranded DNA to antagonize RAD51 loading

(2020) Hongshan Zhang et al.   NUCLEIC ACIDS RESEARCH

Rad51 filament dynamics and its antagonistic modulators

(2020) Alexander Carver et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Sequential role of RAD51 paralog complexes in replication fork remodeling and restart

(2020) Matteo Berti et al.   Nature Communications

RAD51: Beyond the break

(2020) Isabel E. Wassing et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Making choices: DNA replication fork recovery mechanisms

(2020) Christine M. Kondratick et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Single-molecule visualization of human RECQ5 interactions with single-stranded DNA recombination intermediates

(2020) Chaoyou Xue et al.   NUCLEIC ACIDS RESEARCH

The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments

(2019) J Brooks Crickard et al.   NUCLEIC ACIDS RESEARCH

Helicase Mechanisms During Homologous Recombination in Saccharomyces cerevisiae

(2019) J. Brooks Crickard et al.   Annual Review of Biophysics

Single-molecule visualization of human BLM helicase as it acts upon double- and single-stranded DNA substrates

(2019) Chaoyou Xue et al.   NUCLEIC ACIDS RESEARCH

Regulation of Hed1 and Rad54 binding during maturation of the meiosis‐specific presynaptic complex

(2018) J Brooks Crickard et al.   EMBO JOURNAL

A polarized view on DNA under tension

(2018) Joost van Mameren et al.   JOURNAL OF CHEMICAL PHYSICS

RPA and RAD51: fork reversal, fork protection, and genome stability

(2018) Kamakoti P. Bhat et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RPA and RAD51: fork reversal, fork protection, and genome stability

(2018) Kamakoti P. Bhat et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATP Binding to Rad5 Initiates Replication Fork Reversal by Inducing the Unwinding of the Leading Arm and the Formation of the Holliday Junction

(2018) Soochul Shin et al.   Cell Reports

RADX Modulates RAD51 Activity to Control Replication Fork Protection

(2018) Kamakoti P. Bhat et al.   Cell Reports

Shu complex SWS1-SWSAP1 promotes early steps in mouse meiotic recombination

(2018) Carla M. Abreu et al.   Nature Communications

Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase

(2018) J. Brooks Crickard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RAD-ical New Insights into RAD51 Regulation

(2018) Meghan R. Sullivan et al.   Genes

RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks

(2017) Huzefa Dungrawala et al.   MOLECULAR CELL

A change of view: homologous recombination at single-molecule resolution

(2017) Kyle Kaniecki et al.   NATURE REVIEWS GENETICS

Architectural plasticity of human BRCA2–RAD51 complexes in DNA break repair

(2017) Humberto Sánchez et al.   NUCLEIC ACIDS RESEARCH

Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous Recombination Regulation

(2017) Luisina De Tullio et al.   Cell Reports

Visualizing the Nonhomogeneous Structure of RAD51 Filaments Using Nanofluidic Channels

(2016) Louise H. Fornander et al.   LANGMUIR

Tyrosine phosphorylation stimulates activity of human RAD51 recombinase through altered nucleoprotein filament dynamics

(2016) Shyamal Subramanyam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells

(2014) Marcel Reuter et al.   JOURNAL OF CELL BIOLOGY

FBH1 Helicase Disrupts RAD51 Filamentsin Vitroand Modulates Homologous Recombination in Mammalian Cells

(2013) Jitka Simandlova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis

(2013) Carrie A. Adelman et al.   NATURE

Single-molecule sorting reveals how ubiquitylation affects substrate recognition and activities of FBH1 helicase

(2013) Tokiha Masuda-Ozawa et al.   NUCLEIC ACIDS RESEARCH

High-speed atomic force microscope combined with single-molecule fluorescence microscope

(2013) Shingo Fukuda et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Srs2 prevents Rad51 filament formation by repetitive motion on DNA

(2013) Yupeng Qiu et al.   Nature Communications

Human DNA helicase HELQ participates in DNA interstrand crosslink tolerance with ATR and RAD51 paralogs

(2013) Kei-ichi Takata et al.   Nature Communications

Substrate-Selective Repair and Restart of Replication Forks by DNA Translocases

(2013) Rémy Bétous et al.   Cell Reports

Rad51 paralogues Rad55–Rad57 balance the antirecombinase Srs2 in Rad51 filament formation

(2011) Jie Liu et al.   NATURE

Who's who in human recombination: BRCA2 and RAD52

(2010) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-molecule imaging brings Rad51 nucleoprotein filaments into focus

(2010) Anthony L. Forget et al.   TRENDS IN CELL BIOLOGY