Super-resolution mapping of cellular double-strand break resection complexes during homologous recombination

Super-resolution visualization of distinct stalled and broken replication fork structures

(2020) Donna R. Whelan et al.   PLoS Genetics

Ultrafast data mining of molecular assemblies in multiplexed high-density super-resolution images

(2019) Yandong Yin et al.   Nature Communications

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

(2019) Gabriel Balmus et al.   Nature Communications

20 Years of Mre11 Biology: No End in Sight

(2018) Tanya T. Paull   MOLECULAR CELL

Comprehensive Mapping of Histone Modifications at DNA Double-Strand Breaks Deciphers Repair Pathway Chromatin Signatures

(2018) Thomas Clouaire et al.   MOLECULAR CELL

Spatiotemporal dynamics of homologous recombination repair at single collapsed replication forks

(2018) Donna R. Whelan et al.   Nature Communications

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery

(2018) Peter Tonzi et al.   eLife

The Role of PALB2 in the DNA Damage Response and Cancer Predisposition

(2017) Thales Nepomuceno et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Meta-analysis of DNA double-strand break response kinetics

(2017) Jakub A. Kochan et al.   NUCLEIC ACIDS RESEARCH

Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin

(2017) Stefania Pellegrino et al.   Cell Reports

SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination

(2017) Waaqo Daddacha et al.   Cell Reports

Chromatin organization revealed by nanostructure of irradiation induced γH2AX, 53BP1 and Rad51 foci

(2017) Judith Reindl et al.   Scientific Reports

A Method for Quantifying Molecular Interactions Using Stochastic Modelling and Super-Resolution Microscopy

(2017) Keria Bermudez-Hernandez et al.   Scientific Reports

Single Molecule Localization Microscopy of DNA Damage Response Pathways in Cancer.

(2016) Donna R. Whelan et al.   MICROSCOPY AND MICROANALYSIS

Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament

(2016) Chu Jian Ma et al.   NUCLEIC ACIDS RESEARCH

Repair Pathway Choices and Consequences at the Double-Strand Break

(2016) Raphael Ceccaldi et al.   TRENDS IN CELL BIOLOGY

Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks

(2016) Pauline Chanut et al.   Nature Communications

DNA End Resection: Facts and Mechanisms

(2016) Ting Liu et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Super-Resolution Single-Molecule Localization Microscopy: Tricks of the Trade

(2015) Donna R. Whelan et al.   Journal of Physical Chemistry Letters

DNA-Pairing and Annealing Processes in Homologous Recombination and Homology-Directed Repair

(2015) Scott W. Morrical   Cold Spring Harbor Perspectives in Biology

Image artifacts in Single Molecule Localization Microscopy: why optimization of sample preparation protocols matters

(2015) Donna R. Whelan et al.   Scientific Reports

DNA Damage, DNA Repair, Aging, and Neurodegeneration

(2015) Scott Maynard et al.   Cold Spring Harbor Perspectives in Medicine

Replication and transcription on a collision course: eukaryotic regulation mechanisms and implications for DNA stability

(2015) Alessandra Brambati et al.   Frontiers in Genetics

Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1

(2015) Lin Feng et al.   Cell Discovery

DNA double-strand break repair pathway choice and cancer

(2014) Tomas Aparicio et al.   DNA REPAIR

DNA replication stress: Causes, resolution and disease

(2014) Abdelghani Mazouzi et al.   EXPERIMENTAL CELL RESEARCH

53BP1, BRCA1, and the Choice between Recombination and End Joining at DNA Double-Strand Breaks

(2014) J. M. Daley et al.   MOLECULAR AND CELLULAR BIOLOGY

BRCA1 controls homologous recombination at Tus/Ter-stalled mammalian replication forks

(2014) Nicholas A. Willis et al.   NATURE

The NBS1–Treacle complex controls ribosomal RNA transcription in response to DNA damage

(2014) Dorthe H. Larsen et al.   NATURE CELL BIOLOGY

Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response

(2014) Alberto Ciccia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombination and Replication

(2014) A. H. Syeda et al.   Cold Spring Harbor Perspectives in Biology

Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair

(2014) A. Mehta et al.   Cold Spring Harbor Perspectives in Biology

Click chemistry facilitates direct labelling and super-resolution imaging of nucleic acids and proteins

(2014) Anika Raulf et al.   RSC Advances

Super-resolution fluorescence microscopy of the cardiac connexome reveals plakophilin-2 inside the connexin43 plaque

(2013) Esperanza Agullo-Pascual et al.   CARDIOVASCULAR RESEARCH

The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression

(2013) Colleen R. Reczek et al.   JOURNAL OF CELL BIOLOGY

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

(2013) Cristina Escribano-Díaz et al.   MOLECULAR CELL

DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities

(2013) Atsushi Shibata et al.   MOLECULAR CELL

Role of 53BP1 in the Regulation of DNA Double-Strand Break Repair Pathway Choice

(2013) Arun Gupta et al.   RADIATION RESEARCH

53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection

(2013) M. Zimmermann et al.   SCIENCE

DNA Damage Sensing by the ATM and ATR Kinases

(2013) A. Marechal et al.   Cold Spring Harbor Perspectives in Biology

DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network

(2012) Kenneth K. Karanja et al.   CELL CYCLE

BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair

(2012) J. R. Chapman et al.   JOURNAL OF CELL SCIENCE

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Topoisomerase I poisoning results in PARP-mediated replication fork reversal

(2012) Arnab Ray Chaudhuri et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Homologous recombination and its regulation

(2012) L. Krejci et al.   NUCLEIC ACIDS RESEARCH

Double-Strand Break End Resection and Repair Pathway Choice

(2011) Lorraine S. Symington et al.   Annual Review of Genetics

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

(2011) A. V. Nimonkar et al.   GENES & DEVELOPMENT

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

(2011) Sebastian van de Linde et al.   Nature Protocols

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of Homologous Recombination in Eukaryotes

(2010) Wolf-Dietrich Heyer et al.   Annual Review of Genetics

SnapShot: Homologous Recombination in DNA Double-Strand Break Repair

(2010) Gerard Mazón et al.   CELL

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

The MRN complex in double-strand break repair and telomere maintenance

(2010) Brandon J. Lamarche et al.   FEBS LETTERS

QuickPALM: 3D real-time photoactivation nanoscopy image processing in ImageJ

(2010) Ricardo Henriques et al.   NATURE METHODS

BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells

(2010) W K Chu et al.   ONCOGENE

Defective Resection at DNA Double-Strand Breaks Leads to De Novo Telomere Formation and Enhances Gene Targeting

(2010) Woo-Hyun Chung et al.   PLoS Genetics

Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells

(2009) Xiangduo Kong et al.   NUCLEIC ACIDS RESEARCH

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

(2008) S. Gravel et al.   GENES & DEVELOPMENT

Cell Cycle-dependent Complex Formation of BRCA1·CtIP·MRN Is Important for DNA Double-strand Break Repair

(2008) Longchuan Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A forward chemical genetic screen reveals an inhibitor of the Mre11–Rad50–Nbs1 complex

(2008) Aude Dupré et al.   Nature Chemical Biology