Taking the pulse of bioprocesses: at-line and in-line monitoring of mammalian cell cultures
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Title
Taking the pulse of bioprocesses: at-line and in-line monitoring of mammalian cell cultures
Authors
Keywords
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Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 71, Issue -, Pages 191-197
Publisher
Elsevier BV
Online
2021-08-26
DOI
10.1016/j.copbio.2021.08.007
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- (2019) André Guerra et al. CRITICAL REVIEWS IN BIOTECHNOLOGY
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- (2019) Bence Kozma et al. BIOPROCESS AND BIOSYSTEMS ENGINEERING
- Monitoring online biomass with a capacitance sensor during scale-up of industrially relevant CHO cell culture fed-batch processes in single-use bioreactors
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- On-Line Control of Glucose Concentration in High-Yielding Mammalian Cell Cultures Enabled Through Oxygen Transfer Rate Measurements
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- (2013) Boyan Li et al. ANALYTICA CHIMICA ACTA
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