Cohesin in DNA damage response and double-strand break repair

Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation

(2021) Martín A. Rivas et al.   NATURE IMMUNOLOGY

An ever-changing landscape in Roberts syndrome biology: Implications for macromolecular damage

(2021) Michael G. Mfarej et al.   PLoS Genetics

Loop extrusion as a mechanism for formation of DNA damage repair foci

(2021) Coline Arnould et al.   NATURE

Genome folding through loop extrusion by SMC complexes

(2021) Iain F. Davidson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cohesin: Behind Dynamic Genome Topology and Gene Expression Reprogramming

(2021) Carlos Perea-Resa et al.   TRENDS IN CELL BIOLOGY

On the choreography of genome folding: A grand pas de deux of cohesin and CTCF

(2021) Marjon S. van Ruiten et al.   CURRENT OPINION IN CELL BIOLOGY

Functional control of Eco1 through the MCM complex in sister chromatid cohesion

(2021) Atsunori Yoshimura et al.   GENE

Cohesin regulates homology search during recombinational DNA repair

(2021) Aurèle Piazza et al.   NATURE CELL BIOLOGY

Shugoshin 2 is a biomarker for pathological grading and survival prediction in patients with gliomas

(2021) Ying Kao et al.   Scientific Reports

Histone deacetylase (HDAC) inhibitors in cancer: a patent review (2017-present)

(2020) Chunlong Zhao et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Therapeutic opportunities for PLK1 inhibitors: Spotlight on BRCA1-deficiency and triple negative breast cancers

(2020) Iris Alejandra García et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The structural basis for cohesin–CTCF-anchored loops

(2020) Yan Li et al.   NATURE

Division of Labor between PCNA Loaders in DNA Replication and Sister Chromatid Cohesion Establishment

(2020) Hon Wing Liu et al.   MOLECULAR CELL

Cryo-EM structure of the human cohesin-NIPBL-DNA complex

(2020) Zhubing Shi et al.   SCIENCE

MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome

(2020) Ilaria Parenti et al.   Cell Reports

Author Correction: Regulation of sister chromatid cohesion by nuclear PD-L1

(2020) Jia Yu et al.   CELL RESEARCH

Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs

(2020) Madhusudhan Srinivasan et al.   eLife

Pds5A and Pds5B Display Non-redundant Functions in Mitosis and Their Loss Triggers Chk1 Activation

(2020) Naif Al-Jomah et al.   Frontiers in Cell and Developmental Biology

Posttranslational Regulation of DNA Polymerase η, a Connection to Damage-Induced Cohesion in Saccharomyces cerevisiae

(2020) Pei-Shang Wu et al.   GENETICS

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

(2020) James S. Smith et al.   Journal of Translational Medicine

Atezolizumab for First-Line Treatment of PD-L1–Selected Patients with NSCLC

(2020) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural insights into DNA loop extrusion by SMC protein complexes

(2020) Sumanjit Datta et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

DNA damage induces Yap5-dependent transcription of ECO1/CTF7 in Saccharomyces cerevisiae

(2020) Michael G. Mfarej et al.   PLoS One

Cul4-Ddb1 ubiquitin ligases facilitate DNA replication-coupled sister chromatid cohesion through regulation of cohesin acetyltransferase Esco2

(2019) Haitao Sun et al.   PLoS Genetics

Exploiting DNA repair defects in colorectal cancer

(2019) Nicole M. Reilly et al.   Molecular Oncology

Emerging strategies to target the dysfunctional cohesin complex in cancer

(2019) Konstantinos Mintzas et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

A requirement for STAG2 in replication fork progression creates a targetable synthetic lethality in cohesin-mutant cancers

(2019) Gourish Mondal et al.   Nature Communications

Cohesin complex-associated holoprosencephaly

(2019) Paul Kruszka et al.   BRAIN

DNA double-strand break repair-pathway choice in somatic mammalian cells

(2019) Ralph Scully et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer

(2019) Michiel Remmerie et al.   Frontiers in Oncology

The regulation of chromosome segregation via centromere loops

(2019) Josh Lawrimore et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

DNA damage kinase signaling: checkpoint and repair at 30 years

(2019) Michael Charles Lanz et al.   EMBO JOURNAL

Activation of ATR-related protein kinase upon DNA damage recognition

(2019) Minh Ma et al.   CURRENT GENETICS

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection

(2019) Carmen Morales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MRX Increases Chromatin Accessibility at Stalled Replication Forks to Promote Nascent DNA Resection and Cohesin Loading

(2019) Axel Delamarre et al.   MOLECULAR CELL

DNA loop extrusion by human cohesin

(2019) Iain F. Davidson et al.   SCIENCE

Human cohesin compacts DNA by loop extrusion

(2019) Yoori Kim et al.   SCIENCE

Organization of Chromosomal DNA by SMC Complexes

(2019) Stanislau Yatskevich et al.   Annual Review of Genetics

Hydrogen gas inhibits lung cancer progression through targeting SMC3

(2018) Dongchang Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Establishment of DNA-DNA Interactions by the Cohesin Ring

(2018) Yasuto Murayama et al.   CELL

Establishing and dissolving cohesion during the vertebrate cell cycle

(2018) Carmen Morales et al.   CURRENT OPINION IN CELL BIOLOGY

Cohesin RAD21 Gene Promoter Methylation in Patients with Chronic Lymphocytic Leukemia

(2018) Agapi Ioannidou et al.   CYTOGENETIC AND GENOME RESEARCH

The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion

(2018) Miroslav P Ivanov et al.   EMBO JOURNAL

A Novel Frameshift Mutation In Esco2 Gene In Roberts Syndrome

(2018) Eda Mengen et al.   JCPSP-Journal of the College of Physicians and Surgeons Pakistan

Somatic mutation of the cohesin complex subunit confers therapeutic vulnerabilities in cancer

(2018) Yunhua Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing

(2018) Denisse Carvajal-Maldonado et al.   NUCLEIC ACIDS RESEARCH

The effect of aberrant expression and genetic polymorphisms of Rad21 on cervical cancer biology

(2018) Li Xia et al.   Cancer Medicine

Temporal Regulation of ESCO2 Degradation by the MCM Complex, the CUL4-DDB1-VPRBP Complex, and the Anaphase-Promoting Complex

(2018) Masashi Minamino et al.   CURRENT BIOLOGY

Clinical exome sequencing reveals locus heterogeneity and phenotypic variability of cohesinopathies

(2018) Bo Yuan et al.   GENETICS IN MEDICINE

Plk1 overexpression induces chromosomal instability and suppresses tumor development

(2018) Guillermo de Cárcer et al.   Nature Communications

Towards a Unified Model of SMC Complex Function

(2018) Markus Hassler et al.   CURRENT BIOLOGY

Organizational principles of 3D genome architecture

(2018) M. Jordan Rowley et al.   NATURE REVIEWS GENETICS

ESCO2 inhibits tumor metastasis via transcriptionally repressing MMP2 in colorectal cancer

(2018) Xiong-Bo Guo et al.   Cancer Management and Research

Mutations in STAG2 cause an X-linked cohesinopathy associated with undergrowth, developmental delay, and dysmorphia: Expanding the phenotype in males

(2018) Sureni V. Mullegama et al.   Molecular Genetics & Genomic Medicine

Cohesion and cohesin-dependent chromatin organization

(2018) Tomoko Nishiyama   CURRENT OPINION IN CELL BIOLOGY

Independent mechanisms recruit the cohesin loader protein NIPBL to sites of DNA damage

(2017) Christopher Bot et al.   JOURNAL OF CELL SCIENCE

STAG1 mutations cause a novel cohesinopathy characterised by unspecific syndromic intellectual disability

(2017) Daphné Lehalle et al.   JOURNAL OF MEDICAL GENETICS

Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer

(2017) Peng Zhang et al.   MOLECULAR CANCER RESEARCH

Smc3 Deacetylation by Hos1 Facilitates Efficient Dissolution of Sister Chromatid Cohesion during Early Anaphase

(2017) Shuyu Li et al.   MOLECULAR CELL

Cohesin Ubiquitylation and Mobilization Facilitate Stalled Replication Fork Dynamics

(2017) Camilla Frattini et al.   MOLECULAR CELL

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

Molecular mechanism for the regulation of yeast separase by securin

(2017) Shukun Luo et al.   NATURE

The essential kinase ATR: ensuring faithful duplication of a challenging genome

(2017) Joshua C. Saldivar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Non-homologous DNA end joining and alternative pathways to double-strand break repair

(2017) Howard H. Y. Chang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cryo-EM structure of a metazoan separase–securin complex at near-atomic resolution

(2017) Andreas Boland et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the cohesin loader Scc2

(2017) William C. H. Chao et al.   Nature Communications

Cryo-EM structure of a metazoan separase–securin complex at near-atomic resolution

(2017) Andreas Boland et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cohesin Can Remain Associated with Chromosomes during DNA Replication

(2017) James D.P. Rhodes et al.   Cell Reports

Functions, Regulation, and Therapeutic Implications of the ATR Checkpoint Pathway

(2016) Stephanie A. Yazinski et al.   Annual Review of Genetics

CTCF and Cohesin in Genome Folding and Transcriptional Gene Regulation

(2016) Matthias Merkenschlager et al.   Annual Review of Genomics and Human Genetics

Coiled-coils: The long and short of it

(2016) Linda Truebestein et al.   BIOESSAYS

Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome

(2016) Catarina P. Samora et al.   MOLECULAR CELL

Structural basis of cohesin cleavage by separase

(2016) Zhonghui Lin et al.   NATURE

SMC complexes: from DNA to chromosomes

(2016) Frank Uhlmann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SMC1 promotes epithelial-mesenchymal transition in triple-negative breast cancer through upregulating Brachyury

(2016) KAICHUN LI et al.   ONCOLOGY REPORTS

Repair Pathway Choices and Consequences at the Double-Strand Break

(2016) Raphael Ceccaldi et al.   TRENDS IN CELL BIOLOGY

Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis

(2016) Celine Lefebvre et al.   PLOS MEDICINE

C-terminus of Sororin interacts with SA2 and regulates sister chromatid cohesion

(2015) Nenggang Zhang et al.   CELL CYCLE

Cohesin and human disease: lessons from mouse models

(2015) Vijay Pratap Singh et al.   CURRENT OPINION IN CELL BIOLOGY

Mutations in RAD21 Disrupt Regulation of APOB in Patients With Chronic Intestinal Pseudo-Obstruction

(2015) Elena Bonora et al.   GASTROENTEROLOGY

Mutations in the PP2A regulatory subunit B family genesPPP2R5B,PPP2R5CandPPP2R5Dcause human overgrowth

(2015) Chey Loveday et al.   HUMAN MOLECULAR GENETICS

De NovoHeterozygous Mutations inSMC3Cause a Range of Cornelia de Lange Syndrome-Overlapping Phenotypes

(2015) María Concepción Gil-Rodríguez et al.   HUMAN MUTATION

Multiple Levels of Regulation of Sororin by Cdk1 and Aurora B

(2015) Michael T. Borton et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Aurora B Overexpression Causes Aneuploidy and p21Cip1Repression during Tumor Development

(2015) Alejandra González-Loyola et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitotic Transcription Installs Sgo1 at Centromeres to Coordinate Chromosome Segregation

(2015) Hong Liu et al.   MOLECULAR CELL

Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding

(2015) Young-Min Soh et al.   MOLECULAR CELL

Regulation of sister chromatid cohesion during the mitotic cell cycle

(2015) Ge Zheng et al.   Science China-Life Sciences

Increased expression of ESCO1 is correlated with poor patient survival and its role in human bladder cancer

(2015) Shiying Zhang et al.   TUMOR BIOLOGY

Structural Studies Reveal the Functional Modularity of the Scc2-Scc4 Cohesin Loader

(2015) William C.H. Chao et al.   Cell Reports

Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

(2014) D. Mouradov et al.   CANCER RESEARCH

Mutational Landscape of Aggressive Cutaneous Squamous Cell Carcinoma

(2014) C. R. Pickering et al.   CLINICAL CANCER RESEARCH

Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion

(2014) Kodai Hara et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Sequencing of Candidate Chromosome Instability Genes in Endometrial Cancers Reveals Somatic Mutations in ESCO1, CHTF18, and MRE11A

(2014) Jessica C. Price et al.   PLoS One

Cell cycle-specific cleavage of Scc2 regulates its cohesin deposition activity

(2014) J. Woodman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Closing the cohesin ring: Structure and function of its Smc3-kleisin interface

(2014) T. G. Gligoris et al.   SCIENCE

Chk1 Inhibits E2F6 Repressor Function in Response to Replication Stress to Maintain Cell-Cycle Transcription

(2013) Cosetta Bertoli et al.   CURRENT BIOLOGY

Phospho-H2A and Cohesin Specify Distinct Tension-Regulated Sgo1 Pools at Kinetochores and Inner Centromeres

(2013) Hong Liu et al.   CURRENT BIOLOGY

Mutation Spectrum and Genotype-Phenotype Correlation in Cornelia de Lange Syndrome

(2013) Linda Mannini et al.   HUMAN MUTATION

DNA-dependent Protein Kinase Regulates DNA End Resection in Concert with Mre11-Rad50-Nbs1 (MRN) and Ataxia Telangiectasia-mutated (ATM)

(2013) Yi Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Distinct Functions of Human Cohesin-SA1 and Cohesin-SA2 in Double-Strand Break Repair

(2013) X. Kong et al.   MOLECULAR AND CELLULAR BIOLOGY

Glioblastoma Cells Containing Mutations in the Cohesin Component STAG2 Are Sensitive to PARP Inhibition

(2013) M. L. Bailey et al.   MOLECULAR CANCER THERAPEUTICS

Wapl is an essential regulator of chromatin structure and chromosome segregation

(2013) Antonio Tedeschi et al.   NATURE

Causes and consequences of replication stress

(2013) Michelle K. Zeman et al.   NATURE CELL BIOLOGY

Sequential primed kinases create a damage-responsive phosphodegron on Eco1

(2013) Nicholas A Lyons et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of SMC1 in Overcoming Drug Resistance in Triple Negative Breast Cancer

(2013) Sushma Yadav et al.   PLoS One

Structure of the human cohesin inhibitor Wapl

(2013) Z. Ouyang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin

(2013) T. Nishiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic lethality and cancer: cohesin and PARP at the replication fork

(2013) Nigel J. O’Neil et al.   TRENDS IN GENETICS

DNA Damage Sensing by the ATM and ATR Kinases

(2013) A. Marechal et al.   Cold Spring Harbor Perspectives in Biology

The Genetic Landscape of Clinical Resistance to RAF Inhibition in Metastatic Melanoma

(2013) E. M. Van Allen et al.   Cancer Discovery

Importance of Polη for Damage-Induced Cohesion Reveals Differential Regulation of Cohesion Establishment at the Break Site and Genome-Wide

(2013) Elin Enervald et al.   PLoS Genetics

Cohesin’s DNA Exit Gate Is Distinct from Its Entrance Gate and Is Regulated by Acetylation

(2012) Kok-Lung Chan et al.   CELL

Haploinsufficiency ofSGO1results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis

(2012) Hiroshi Y. Yamada et al.   CELL CYCLE

SUMOylation of the α-Kleisin Subunit of Cohesin Is Required for DNA Damage-Induced Cohesion

(2012) Alexandra McAleenan et al.   CURRENT BIOLOGY

A SUMO-Dependent Step during Establishment of Sister Chromatid Cohesion

(2012) Seba Almedawar et al.   CURRENT BIOLOGY

The Ancient and Evolving Roles of Cohesin in Gene Expression and DNA Repair

(2012) Dale Dorsett et al.   CURRENT BIOLOGY

Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl

(2012) N. Wu et al.   GENES & DEVELOPMENT

HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle

(2012) Matthew A. Deardorff et al.   NATURE

Post-replicative repair involves separase-dependent removal of the kleisin subunit of cohesin

(2012) Alexandra McAleenan et al.   NATURE

Recurrent R-spondin fusions in colon cancer

(2012) Somasekar Seshagiri et al.   NATURE

Phosphorylation-enabled binding of SGO1–PP2A to cohesin protects sororin and centromeric cohesion during mitosis

(2012) Hong Liu et al.   NATURE CELL BIOLOGY

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

(2012) Michael Krauthammer et al.   NATURE GENETICS

Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia

(2012) Kim De Keersmaecker et al.   NATURE GENETICS

Sister Chromatid Cohesion

(2012) J.-M. Peters et al.   Cold Spring Harbor Perspectives in Biology

Deregulation of RAD21 and RUNX1 expression in endometrial cancer

(2012) ANNA SUPERNAT et al.   Oncology Letters

The Smc complexes in DNA damage response

(2012) Nan Wu et al.   Cell and Bioscience

Synthetic Lethality of Cohesins with PARPs and Replication Fork Mediators

(2012) Jessica L. McLellan et al.   PLoS Genetics

Phosphorylation of Chromosome Core Components May Serve as Axis Marks for the Status of Chromosomal Events during Mammalian Meiosis

(2012) Tomoyuki Fukuda et al.   PLoS Genetics

Interaction of Sororin Protein with Polo-like Kinase 1 Mediates Resolution of Chromosomal Arm Cohesion

(2011) Nenggang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of sororin by Cdk1-mediated phosphorylation

(2011) Megan R. Dreier et al.   JOURNAL OF CELL SCIENCE

Cdk1-Dependent Destruction of Eco1 Prevents Cohesion Establishment after S Phase

(2011) Nicholas A. Lyons et al.   MOLECULAR CELL

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

(2011) Xose S. Puente et al.   NATURE

Alteration of cohesin genes in myeloid diseases

(2010) Julien Rocquain et al.   AMERICAN JOURNAL OF HEMATOLOGY

Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC

(2010) Zhong-Zhe Lin et al.   BMC CANCER

Phosphorylation and Activation of Cell Division Cycle Associated 5 by Mitogen-Activated Protein Kinase Play a Crucial Role in Human Lung Carcinogenesis

(2010) M.-H. Nguyen et al.   CANCER RESEARCH

Sororin Mediates Sister Chromatid Cohesion by Antagonizing Wapl

(2010) Tomoko Nishiyama et al.   CELL

Hos1 Is a Lysine Deacetylase for the Smc3 Subunit of Cohesin

(2010) Bo Xiong et al.   CURRENT BIOLOGY

ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery

(2010) Francesca Ammazzalorso et al.   EMBO JOURNAL

A Conserved Motif at the C Terminus of Sororin Is Required for Sister Chromatid Cohesion

(2010) Frank M. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide Reinforcement of Cohesin Binding at Pre-existing Cohesin Sites in Response to Ionizing Radiation in Human Cells

(2010) Beom-Jun Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hos1 Deacetylates Smc3 to Close the Cohesin Acetylation Cycle

(2010) Vanessa Borges et al.   MOLECULAR CELL

Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation

(2010) Philip Zegerman et al.   NATURE

Mediator and cohesin connect gene expression and chromatin architecture

(2010) Michael H. Kagey et al.   NATURE

Sororin cooperates with the acetyltransferase Eco2 to ensure DNA replication-dependent sister chromatid cohesion

(2010) A. L. Lafont et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis

(2010) Fangwei Wang et al.   SCIENCE

Buck the establishment: reinventing sister chromatid cohesion

(2010) Robert V. Skibbens   TRENDS IN CELL BIOLOGY

RAD50, an SMC family member with multiple roles in DNA break repair: how does ATP affect function?

(2009) Eri Kinoshita et al.   CHROMOSOME RESEARCH

Dynamics of the bacterial SMC complex and SMC-like proteins involved in DNA repair

(2009) Peter L. Graumann et al.   CHROMOSOME RESEARCH

Budding Yeast Wpl1(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction

(2009) Takashi Sutani et al.   CURRENT BIOLOGY

The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells

(2009) Erwan Watrin et al.   EMBO JOURNAL

Distinct Targets of the Eco1 Acetyltransferase Modulate Cohesion in S Phase and in Response to DNA Damage

(2009) Jill M. Heidinger-Pauli et al.   MOLECULAR CELL

Building Sister Chromatid Cohesion: Smc3 Acetylation Counteracts an Antiestablishment Activity

(2009) Benjamin D. Rowland et al.   MOLECULAR CELL

Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes

(2009) Elsa Callén et al.   MOLECULAR CELL

Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin

(2009) C. Bauerschmidt et al.   NUCLEIC ACIDS RESEARCH

Increased sister chromatid cohesion and DNA damage response factor localization at an enzyme-induced DNA double-strand break in vertebrate cells

(2009) Helen Dodson et al.   NUCLEIC ACIDS RESEARCH

Dosage Effects of Cohesin Regulatory Factor PDS5 on Mammalian Development: Implications for Cohesinopathies

(2009) Bin Zhang et al.   PLoS One

Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA

(2008) Ekaterina Revenkova et al.   HUMAN MOLECULAR GENETICS

Regulation of Intra-S Phase Checkpoint by Ionizing Radiation (IR)-dependent and IR-independent Phosphorylation of SMC3

(2008) Hao Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A handcuff model for the cohesin complex

(2008) Nenggang Zhang et al.   JOURNAL OF CELL BIOLOGY

Acetylation of Smc3 by Eco1 Is Required for S Phase Sister Chromatid Cohesion in Both Human and Yeast

(2008) Jinglan Zhang et al.   MOLECULAR CELL

The Kleisin Subunit of Cohesin Dictates Damage-Induced Cohesion

(2008) Jill M. Heidinger-Pauli et al.   MOLECULAR CELL

Cohesin mediates transcriptional insulation by CCCTC-binding factor

(2008) Kerstin S. Wendt et al.   NATURE

Overexpression of Separase induces aneuploidy and mammary tumorigenesis

(2008) N. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

(2008) T. D. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Molecular Determinant for the Establishment of Sister Chromatid Cohesion

(2008) E. U nal et al.   SCIENCE

Eco1-Dependent Cohesin Acetylation During Establishment of Sister Chromatid Cohesion

(2008) T. R. Ben-Shahar et al.   SCIENCE