Pyroptosis Adjuvants: Gram-Scale Production, Cascade Catalysis, and In Situ Antitumor Immunity Activation

A Potent Cancer Vaccine Adjuvant System for Particleization of Short, Synthetic CD8+ T Cell Epitopes

(2021) Xuedan He et al.   ACS Nano

Inspired Epigenetic Modulation Synergy with Adenosine Inhibition Elicits Pyroptosis and Potentiates Cancer Immunotherapy

(2021) Honggang Xiong et al.   ADVANCED FUNCTIONAL MATERIALS

Ultrasound-Augmented Mitochondrial Calcium Ion Overload by Calcium Nanomodulator to Induce Immunogenic Cell Death

(2021) Pan Zheng et al.   NANO LETTERS

A Virus‐Spike Tumor‐Activatable Pyroptotic Agent

(2021) Sadia Nadeem et al.   Small

Emerging concepts in the science of vaccine adjuvants

(2021) Bali Pulendran et al.   NATURE REVIEWS DRUG DISCOVERY

Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

(2021) Chi Zhang et al.   Nature Communications

In situ cancer vaccination using lipidoid nanoparticles

(2021) Jinjin Chen et al.   Science Advances

MnO2-Based Nanomotors with Active Fenton-like Mn2+ Delivery for Enhanced Chemodynamic Therapy

(2021) Juanfeng Ou et al.   ACS Applied Materials & Interfaces

Charge‐Reversal Polymer Nano‐modulators for Photodynamic Immunotherapy of Cancer

(2021) Shasha He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biodegradable Upconversion Nanoparticles Induce Pyroptosis for Cancer Immunotherapy

(2021) Binbin Ding et al.   NANO LETTERS

Manganese Oxide Nanomaterials: Synthesis, Properties, and Theranostic Applications

(2020) Binbin Ding et al.   ADVANCED MATERIALS

Engineered immunogen binding to alum adjuvant enhances humoral immunity

(2020) Tyson J. Moyer et al.   NATURE MEDICINE

Self‐Boosting Catalytic Nanoreactor Integrated with Triggerable Crosslinking Membrane Networks for Initiation of Immunogenic Cell Death by Pyroptosis

(2020) Junjie Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

(2020) Zhibin Zhang et al.   NATURE

A bioorthogonal system reveals antitumour immune function of pyroptosis

(2020) Qinyang Wang et al.   NATURE

MnO x Nanospikes as Nanoadjuvants and Immunogenic Cell Death Drugs with Enhanced Antitumor Immunity and Antimetastatic Effect

(2020) Binbin Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cell Death Mediated by the Pyroptosis Pathway with the Aid of Nanotechnology: Prospects for Cancer Therapy

(2020) Dan Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Programming cell pyroptosis with biomimetic nanoparticles for solid tumor immunotherapy

(2020) Pengfei Zhao et al.   BIOMATERIALS

Synergistic tumor immunological strategy by combining tumor nanovaccine with gene-mediated extracellular matrix scavenger

(2020) Yingying Hu et al.   BIOMATERIALS

Sono/Photodynamic Nanomedicine‐Elicited Cancer Immunotherapy

(2020) Yuce Li et al.   ADVANCED FUNCTIONAL MATERIALS

Second Near‐Infrared Photothermal Semiconducting Polymer Nanoadjuvant for Enhanced Cancer Immunotherapy

(2020) Jingchao Li et al.   ADVANCED MATERIALS

Glucose Oxidase‐Instructed Multimodal Synergistic Cancer Therapy

(2019) Lian‐Hua Fu et al.   ADVANCED MATERIALS

Biomimetic Hybrid Nanozymes with Self-Supplied H+ and Accelerated O2 Generation for Enhanced Starvation and Photodynamic Therapy against Hypoxic Tumors

(2019) Xue Yang et al.   NANO LETTERS

Near-Infrared II Phototherapy Induces Deep Tissue Immunogenic Cell Death and Potentiates Cancer Immunotherapy

(2019) Yinchu Ma et al.   ACS Nano

Epigenetics-Based Tumor Cells Pyroptosis for Enhancing the Immunological Effect of Chemotherapeutic Nanocarriers

(2019) Jin-Xuan Fan et al.   NANO LETTERS

Recent Advances in Glucose‐Oxidase‐Based Nanocomposites for Tumor Therapy

(2019) Man Wang et al.   Small

MnO2 Motor: A Prospective Cancer-Starving Therapy Promoter

(2018) Yao-Hui Zhang et al.   ACS Applied Materials & Interfaces

Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2 -Based Nanoagent to Enhance Chemodynamic Therapy

(2018) Li-Sen Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tailoring inorganic nanoadjuvants towards next-generation vaccines

(2018) Xia Li et al.   CHEMICAL SOCIETY REVIEWS

Catalytic chemistry of glucose oxidase in cancer diagnosis and treatment

(2018) Lian-Hua Fu et al.   CHEMICAL SOCIETY REVIEWS

Large-Pore Mesoporous-Silica-Coated Upconversion Nanoparticles as Multifunctional Immunoadjuvants with Ultrahigh Photosensitizer and Antigen Loading Efficiency for Improved Cancer Photodynamic Immunotherapy

(2018) Binbin Ding et al.   ADVANCED MATERIALS

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Designer vaccine nanodiscs for personalized cancer immunotherapy

(2016) Rui Kuai et al.   NATURE MATERIALS

Stimulation of In Vivo Antitumor Immunity with Hollow Mesoporous Silica Nanospheres

(2015) Xiupeng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Morphologically Virus-Like Fullerenol Nanoparticles Act as the Dual-Functional Nanoadjuvant for HIV-1 Vaccine

(2013) Ligeng Xu et al.   ADVANCED MATERIALS

Key roles of adjuvants in modern vaccines

(2013) Steven G Reed et al.   NATURE MEDICINE

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE