- Home
- Publications
- Publication Search
- Publication Details
Title
Osteosarcoma mechanobiology and therapeutic targets
Authors
Keywords
-
Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume 179, Issue 2, Pages 201-217
Publisher
Wiley
Online
2021-10-23
DOI
10.1111/bph.15713
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Integrin-Linked Kinase Links Integrin Activation to Invadopodia Function and Invasion via the p(T567)-Ezrin/NHERF1/NHE1 Pathway
- (2021) Maria Raffaella Greco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanisms of Resistance to Conventional Therapies for Osteosarcoma
- (2021) Louise Marchandet et al. Cancers
- Potential Antimetastatic Effect of Timosaponin AIII against Human Osteosarcoma Cells through Regulating the Integrin/FAK/Cofilin Axis
- (2021) Yi-Hsien Hsieh et al. Pharmaceuticals
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes
- (2021) Stephen PH Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors
- (2021) Stephen PH Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- A retrospective analysis of 11 dogs with surface osteosarcoma
- (2021) Matthew R. Cook et al. Veterinary and Comparative Oncology
- Understanding and Modeling Metastasis Biology to Improve Therapeutic Strategies for Combating Osteosarcoma Progression
- (2020) Timothy M. Fan et al. Frontiers in Oncology
- Intrafibrillar Mineralized Collagen–Hydroxyapatite-Based Scaffolds for Bone Regeneration
- (2020) Le Yu et al. ACS Applied Materials & Interfaces
- Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering
- (2020) Mian Wei et al. Science Advances
- Histone deacetylase inhibition prevents the growth of primary and metastatic osteosarcoma
- (2020) Jeremy J. McGuire et al. INTERNATIONAL JOURNAL OF CANCER
- The Hippo in the room: Targeting the Hippo signalling pathway for osteosarcoma therapies
- (2020) Emel Rothzerg et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Can Denosumab be used in combination with Doxorubicin in Osteosarcoma?
- (2020) Francesca Punzo et al. Oncotarget
- Hydrogel as a Biomaterial for Bone Tissue Engineering: A Review
- (2020) Shuai Yue et al. Nanomaterials
- Cofilin-1 Is a Mechanosensitive Regulator of Transcription
- (2020) Catarina Domingues et al. Frontiers in Cell and Developmental Biology
- Targeting Mechanotransduction in Osteosarcoma: A Comparative Oncology Perspective
- (2020) Anita K. Luu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A multiple drug loaded, functionalized pH-sensitive nanocarrier as therapeutic and epigenetic modulator for osteosarcoma
- (2020) Ye Yuan et al. Scientific Reports
- Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling
- (2020) Qi Zhou et al. MACROMOLECULAR BIOSCIENCE
- The YAP/TEAD Axis as a New Therapeutic Target in Osteosarcoma: Effect of Verteporfin and CA3 on Primary Tumor Growth
- (2020) Sarah Morice et al. Cancers
- Expression profiling of DNA methyl transferase I (DNMT1) and efficacy of a DNA-hypomethylating agent (decitabine) in combination with chemotherapy in osteosarcoma
- (2020) Parunya Chaiyawat et al. Journal of Bone Oncology
- Elevated H3K27me3 levels sensitize osteosarcoma to cisplatin
- (2019) Chao He et al. Clinical Epigenetics
- Epigenetic biomarker screening by FLIM-FRET for combination therapy in ER+ breast cancer
- (2019) Wenjie Liu et al. Clinical Epigenetics
- YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility
- (2019) Devon E. Mason et al. JOURNAL OF CELL BIOLOGY
- The inclusion of zinc into mineralized collagen scaffolds for craniofacial bone repair applications
- (2019) Aleczandria S. Tiffany et al. Acta Biomaterialia
- On the relationship of YAP and FAK in hMSCs and osteosarcoma cells: Discrimination of FAK modulation by nuclear YAP depletion or YAP silencing
- (2019) Ayman Husari et al. CELLULAR SIGNALLING
- Crosshatch nanofiber networks of tunable interfiber spacing induce plasticity in cell migration and cytoskeletal response
- (2019) Aniket Jana et al. FASEB JOURNAL
- Excess of second tumors in denosumab-treated patients: a metabolic hypothesis
- (2019) Valeria Tovazzi et al. Future Oncology
- New Insights about the Wnt/β-Catenin Signaling Pathway in Primary Bone Tumors and Their Microenvironment: A Promising Target to Develop Therapeutic Strategies?
- (2019) Danieau et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds
- (2019) Xiaoyan Ren et al. Science Advances
- Mechanical Roles in Formation of Oriented Collagen Fibers
- (2019) Jiexiang Lin et al. TISSUE ENGINEERING PART B-REVIEWS
- Connective tissue growth factor stimulates osteosarcoma cell migration and induces osteosarcoma metastasis by upregulating VCAM-1 expression
- (2018) Chun-Han Hou et al. BIOCHEMICAL PHARMACOLOGY
- Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines
- (2018) Helin Feng et al. Oncotarget
- Transcriptional addiction in cancer cells is mediated by YAP/TAZ through BRD4
- (2018) Francesca Zanconato et al. NATURE MEDICINE
- Activation of Estrogen Receptor Alpha by Decitabine Inhibits Osteosarcoma Growth and Metastasis
- (2018) Maria Angeles Lillo Osuna et al. CANCER RESEARCH
- Bone-Cancer Assessment and Destruction Pattern Analysis in Long-Bone X-ray Image
- (2018) Oishila Bandyopadhyay et al. JOURNAL OF DIGITAL IMAGING
- Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
- (2018) Iván M. Moya et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Targeting the Wnt/β-catenin pathway in human osteosarcoma cells
- (2018) Fang Fang et al. Oncotarget
- NF-κB signaling and integrin-β1 inhibition attenuates osteosarcoma metastasis via increased cell apoptosis
- (2018) Rui Li et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Combining 2D angiogenesis and 3D osteosarcoma microtissues to improve vascularization
- (2017) Hassan Chaddad et al. EXPERIMENTAL CELL RESEARCH
- Modifying the strength and strain concentration profile within collagen scaffolds using customizable arrays of poly-lactic acid fibers
- (2017) Laura C. Mozdzen et al. Journal of the Mechanical Behavior of Biomedical Materials
- Mechanobiology of YAP and TAZ in physiology and disease
- (2017) Tito Panciera et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Nuclear Actin in Development and Transcriptional Reprogramming
- (2017) Shinji Misu et al. Frontiers in Genetics
- Real-Time Multiplex Kinase Phosphorylation Sensors in Living Cells
- (2017) Nur P. Damayanti et al. ACS Sensors
- Biodegradation and Osteosarcoma Cell Cultivation on Poly(aspartic acid) Based Hydrogels
- (2016) Dávid Juriga et al. ACS Applied Materials & Interfaces
- Suberanilohydroxamic acid (vorinostat) synergistically enhances the cytotoxicity of doxorubicin and cisplatin in osteosarcoma cell lines
- (2016) Aleksandra Pettke et al. ANTI-CANCER DRUGS
- Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation
- (2016) Zhantao Deng et al. International Journal of Biological Sciences
- Ezrin Inhibition Up-regulates Stress Response Gene Expression
- (2016) Haydar Çelik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Zoledronate in combination with chemotherapy and surgery to treat osteosarcoma (OS2006): a randomised, multicentre, open-label, phase 3 trial
- (2016) Sophie Piperno-Neumann et al. LANCET ONCOLOGY
- Disruption of Collagen Matrix Alignment in Osteolytic Bone Metastasis Induced by Breast Cancer
- (2016) Aiko Sekita et al. MATERIALS TRANSACTIONS
- Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment
- (2016) Huy Quang Le et al. NATURE CELL BIOLOGY
- Update on Survival in Osteosarcoma
- (2016) Megan E. Anderson ORTHOPEDIC CLINICS OF NORTH AMERICA
- Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis
- (2016) Qian Yin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intratumoral oxygen gradients mediate sarcoma cell invasion
- (2016) Daniel M. Lewis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Beyond quantification: in situ analysis of transcriptome and pre-mRNA alternative splicing at the nanoscale
- (2016) Yi Cui et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2–p53 signaling
- (2016) Chuhai Xie et al. OncoTargets and Therapy
- Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential
- (2016) Ranran Sun et al. Oncotarget
- Application of Collagen Scaffold in Tissue Engineering: Recent Advances and New Perspectives
- (2016) Chanjuan Dong et al. Polymers
- Bone Quality in Paget’s Disease of Bone
- (2016) Frederick R. Singer Current Osteoporosis Reports
- Cortical Bone Porosity: What Is It, Why Is It Important, and How Can We Detect It?
- (2016) D. M. L. Cooper et al. Current Osteoporosis Reports
- Cytoskeletal tension induces the polarized architecture of the nucleus
- (2015) Dong-Hwee Kim et al. BIOMATERIALS
- Osteoprotegerin activates osteosarcoma cells that co-express RANK and RANKL
- (2015) Kevin Marley et al. EXPERIMENTAL CELL RESEARCH
- Modifications to Nano- and Microstructural Quality and the Effects on Mechanical Integrity in Paget's Disease of Bone
- (2015) Elizabeth A Zimmermann et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Ezrin regulates focal adhesion and invadopodia dynamics by altering calpain activity to promote breast cancer cell invasion
- (2015) Victoria Hoskin et al. MOLECULAR BIOLOGY OF THE CELL
- Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells
- (2015) YINJUN HUANG et al. Molecular Medicine Reports
- Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy
- (2015) Yi Cui et al. NUCLEIC ACIDS RESEARCH
- Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim
- (2015) Xiaowei Shao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intranuclear Actin Regulates Osteogenesis
- (2015) Buer Sen et al. STEM CELLS
- Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma
- (2015) Yang-Fan Lv et al. Scientific Reports
- The HDAC Inhibitor Vorinostat Diminishes theIn VitroMetastatic Behavior of Osteosarcoma Cells
- (2015) Xiaodong Mu et al. Biomed Research International
- Optimum 3D Matrix Stiffness for Maintenance of Cancer Stem Cells Is Dependent on Tissue Origin of Cancer Cells
- (2015) Esmaiel Jabbari et al. PLoS One
- The genetic basis for inactivation of Wnt pathway in human osteosarcoma
- (2014) Xiaoling Du et al. BMC CANCER
- Regulation of YAP by Mechanical Strain through Jnk and Hippo Signaling
- (2014) Veronica A. Codelia et al. CURRENT BIOLOGY
- Bisphosphonates Inhibit Osteosarcoma-Mediated Osteolysis Via Attenuation of Tumor Expression of MCP-1 and RANKL
- (2014) Tetsuro Ohba et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Physical influences of the extracellular environment on cell migration
- (2014) Guillaume Charras et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Micro-Computed Tomography Derived Anisotropy Detects Tumor Provoked Deviations in Bone in an Orthotopic Osteosarcoma Murine Model
- (2014) Heather A. Cole et al. PLoS One
- Separate and Combined Effects of DNMT and HDAC Inhibitors in Treating Human Multi-Drug Resistant Osteosarcoma HosDXR150 Cell Line
- (2014) Enrico Capobianco et al. PLoS One
- Bone Environment is Essential for Osteosarcoma Development from Transformed Mesenchymal Stem Cells
- (2014) Ruth Rubio et al. STEM CELLS
- The Histone Deacetylase Inhibitor, MS-275 (Entinostat), Downregulates c-FLIP, Sensitizes Osteosarcoma Cells to FasL, and Induces the Regression of Osteosarcoma Lung Metastases
- (2013) Krithi Rao-Bindal et al. CURRENT CANCER DRUG TARGETS
- Wnt Pathway in Osteosarcoma, from Oncogenic to Therapeutic
- (2013) Yu Cai et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Osteopetrosis: genetics, treatment and new insights into osteoclast function
- (2013) Cristina Sobacchi et al. Nature Reviews Endocrinology
- Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA
- (2013) Z Zou et al. ONCOGENE
- Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover
- (2013) Y. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Downregulation of ERK signaling impairs U2OS osteosarcoma cell migration in collagen matrix by suppressing MMP9 production
- (2013) BARUN POUDEL et al. Oncology Letters
- The role of osteoclasts and tumour-associated macrophages in osteosarcoma metastasis
- (2012) Liliana Endo-Munoz et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Prognostic factors in canine appendicular osteosarcoma – a meta-analysis
- (2012) Ilse Boerman et al. BMC Veterinary Research
- Dynamic analysis of lung metastasis by mouse osteosarcoma LM8: VEGF is a candidate for anti-metastasis therapy
- (2012) Takaaki Tanaka et al. CLINICAL & EXPERIMENTAL METASTASIS
- YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29
- (2012) Karen Tumaneng et al. NATURE CELL BIOLOGY
- Actin cap associated focal adhesions and their distinct role in cellular mechanosensing
- (2012) Dong-Hwee Kim et al. Scientific Reports
- Stretch-inducible Expression of Connective Tissue Growth Factor (CTGF) in Human Osteoblasts-like Cells is Mediated by PI3K-JNK Pathway
- (2011) Li-Wei Xiao et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The Wnt signaling pathway: implications for therapy in osteosarcoma
- (2011) Peter McQueen et al. Expert Review of Anticancer Therapy
- Formulated siRNAs targeting Rankl prevent osteolysis and enhance chemotherapeutic response in osteosarcoma models
- (2011) Julie Rousseau et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells
- (2011) G Bulut et al. ONCOGENE
- Loss of Osteoclasts Contributes to Development of Osteosarcoma Pulmonary Metastases
- (2010) L. Endo-Munoz et al. CANCER RESEARCH
- Genetics of bone diseases: Paget's disease, fibrous dysplasia, osteopetrosis, and osteogenesis imperfecta
- (2010) Laetitia Michou et al. JOINT BONE SPINE
- Phosphorylated ezrin is located in the nucleus of the osteosarcoma cell
- (2010) Claudio Di Cristofano et al. MODERN PATHOLOGY
- Wnt signal transduction pathways
- (2010) Yuko Komiya et al. Organogenesis
- Hydrogels as extracellular matrix mimics for 3D cell culture
- (2009) Mark W. Tibbitt et al. BIOTECHNOLOGY AND BIOENGINEERING
- Bisphosphonates: Mechanism of Action and Role in Clinical Practice
- (2009) Matthew T. Drake et al. MAYO CLINIC PROCEEDINGS
- Beta4 integrin promotes osteosarcoma metastasis and interacts with ezrin
- (2009) X Wan et al. ONCOGENE
- Aminobisphosphonates Cause Osteoblast Apoptosis and Inhibit Bone Nodule Formation In Vitro
- (2008) Aymen I. Idris et al. CALCIFIED TISSUE INTERNATIONAL
- The actin-cytoskeleton linker protein ezrin is regulated during osteosarcoma metastasis by PKC
- (2008) L Ren et al. ONCOGENE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now