Potential Antimetastatic Effect of Timosaponin AIII against Human Osteosarcoma Cells through Regulating the Integrin/FAK/Cofilin Axis

Cytoskeletal Proteins in Cancer and Intracellular Stress: A Therapeutic Perspective

(2020) Mei Shan Ong et al.   Cancers

Apelin Affects the Progression of Osteoarthritis by Regulating VEGF-Dependent Angiogenesis and miR-150-5p Expression in Human Synovial Fibroblasts

(2020) Yu-Han Wang et al.   Cells

Silencing PROK2 Inhibits Invasion of Human Cervical Cancer Cells by Targeting MMP15 Expression

(2020) Min-Hua Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of extracelluar matrix in osteosarcoma progression and metastasis

(2020) Juncheng Cui et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo

(2020) Jingjing Liu et al.   LIFE SCIENCES

Periodontal pathogens promote cancer aggressivity via TLR/MyD88 triggered activation of Integrin/FAK signaling that is therapeutically reversible by a probiotic bacteriocin

(2020) Pachiyappan Kamarajan et al.   PLoS Pathogens

Involvement of Actin and Actin-Binding Proteins in Carcinogenesis

(2020) Magdalena Izdebska et al.   Cells

Reciprocal Interplay Between Fibrillar Collagens and Collagen-Binding Integrins: Implications in Cancer Progression and Metastasis

(2020) Isabelle Bourgot et al.   Frontiers in Oncology

Timosaponin AIII inhibits metastasis of renal carcinoma cells through suppressing cathepsin C expression by AKT/miR-129-5p axis

(2019) Kuang-Chung Chiang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Timosaponin AIII, a steroidal saponin, exhibits anti-tumor effect on taxol-resistant cells in vitro and in vivo

(2019) Xiao-Yu Song et al.   STEROIDS

Licochalcone A-Induced Apoptosis Through the Activation of p38MAPK Pathway Mediated Mitochondrial Pathways of Apoptosis in Human Osteosarcoma Cells In Vitro and In Vivo

(2019) Lin et al.   Cells

Tumor Syndromes Predisposing to Osteosarcoma

(2018) Meera Hameed et al.   ADVANCES IN ANATOMIC PATHOLOGY

Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions

(2018) Markus Schulze et al.   BMC CANCER

LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance

(2018) Helen Aggelou et al.   VIRCHOWS ARCHIV

Synergistic antimetastatic effect of cotreatment with licochalcone A and sorafenib on human hepatocellular carcinoma cells through the inactivation of MKK4/JNK and uPA expression

(2018) Min-Hua Wu et al.   ENVIRONMENTAL TOXICOLOGY

Apoptosis and G2/M cell cycle arrest induced by a timosaponin A3 from Anemarrhena asphodeloides Bunge on AsPC-1 pancreatic cancer cells

(2018) Yumi Kim et al.   PHYTOMEDICINE

Dioscin induces prostate cancer cell apoptosis through activation of estrogen receptor-β

(2017) Xufeng Tao et al.   Cell Death & Disease

Dioscin Inhibits HSC-T6 Cell Migration via Adjusting SDC-4 Expression: Insights from iTRAQ-Based Quantitative Proteomics

(2017) Lianhong Yin et al.   Frontiers in Pharmacology

Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways

(2016) Okkeun Jung et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Timosaponin AIII inhibits melanoma cell migration by suppressing COX-2 andin vivotumor metastasis

(2016) Ki Mo Kim et al.   CANCER SCIENCE

Saponins from Chinese Medicines as Anticancer Agents

(2016) Xiao-Huang Xu et al.   MOLECULES

Roles of cofilin in development and its mechanisms of regulation

(2015) Kazumasa Ohashi   DEVELOPMENT GROWTH & DIFFERENTIATION

Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation

(2015) M. H. Kim et al.   EMBO JOURNAL

Multiple FAS1 domains and the RGD motif of TGFBI act cooperatively to bind αvβ3 integrin, leading to anti-angiogenic and anti-tumor effects

(2013) Hye-Nam Son et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Timosaponin AIII Suppresses Hepatocyte Growth Factor-Induced Invasive Activity through Sustained ERK Activation in Breast Cancer MDA-MB-231 Cells

(2013) Chung-Hsin Tsai et al.   Evidence-based Complementary and Alternative Medicine

Incidence, epidemiology and treatment results of osteosarcoma in Finland – a nationwide population-based study

(2011) Mika Sampo et al.   ACTA ONCOLOGICA

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Cytotoxic and Antineoplastic Activity of Timosaponin A-III for Human Colon Cancer Cells

(2011) You-Jin Kang et al.   JOURNAL OF NATURAL PRODUCTS

Temporal blastemal cell gene expression analysis in the kidney reveals new Wnt and related signaling pathway genes to be essential for Wilms' tumor onset

(2011) M Maschietto et al.   Cell Death & Disease

ADF/Cofilin: a functional node in cell biology

(2010) Barbara W. Bernstein et al.   TRENDS IN CELL BIOLOGY

Signal transduction by focal adhesion kinase in cancer

(2009) Jihe Zhao et al.   CANCER AND METASTASIS REVIEWS

Cell Adhesion-dependent Cofilin Serine 3 Phosphorylation by the Integrin-linked Kinase·c-Src Complex

(2008) Yong-Bae Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY