Stiffness of Nanoparticulate Mineralized Collagen Scaffolds Triggers Osteogenesis via Mechanotransduction and Canonical Wnt Signaling

Shape-fitting collagen-PLA composite promotes osteogenic differentiation of porcine adipose stem cells

(2019) Marley J. Dewey et al.   Journal of the Mechanical Behavior of Biomedical Materials

Extracellular matrix type modulates mechanotransduction of stem cells

(2019) Alice E. Stanton et al.   Acta Biomaterialia

Osteoprotegerin reduces osteoclast resorption activity without affecting osteogenesis on nanoparticulate mineralized collagen scaffolds

(2019) Xiaoyan Ren et al.   Science Advances

YAP/TAZ upstream signals and downstream responses

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Role of Wnt11 during Osteogenic Differentiation of Human Mesenchymal Stem Cells on Microstructured Titanium Surfaces

(2018) Barbara D. Boyan et al.   Scientific Reports

Extracellular matrix stiffness controls osteogenic differentiation of mesenchymal stem cells mediated by integrin α5

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Modifying the strength and strain concentration profile within collagen scaffolds using customizable arrays of poly-lactic acid fibers

(2017) Laura C. Mozdzen et al.   Journal of the Mechanical Behavior of Biomedical Materials

YAP regulates cell mechanics by controlling focal adhesion assembly

(2017) Giorgia Nardone et al.   Nature Communications

Nonmineralized and Mineralized Collagen Scaffolds Induce Differential Osteogenic Signaling Pathways in Human Mesenchymal Stem Cells

(2017) Qi Zhou et al.   Advanced Healthcare Materials

Bioinspired Collagen Scaffolds in Cranial Bone Regeneration: From Bedside to Bench

(2017) Justine C. Lee et al.   Advanced Healthcare Materials

Nanoparticulate mineralized collagen scaffolds induce in vivo bone regeneration independent of progenitor cell loading or exogenous growth factor stimulation

(2016) Xiaoyan Ren et al.   BIOMATERIALS

Nanoparticulate Mineralized Collagen Scaffolds and BMP-9 Induce a Long-Term Bone Cartilage Construct in Human Mesenchymal Stem Cells

(2016) Xiaoyan Ren et al.   Advanced Healthcare Materials

Extracellular matrix stiffness dictates Wnt expression through integrin pathway

(2016) Jing Du et al.   Scientific Reports

Osteogenesis on nanoparticulate mineralized collagen scaffolds via autogenous activation of the canonical BMP receptor signaling pathway

(2015) Xiaoyan Ren et al.   BIOMATERIALS

Optimizing Collagen Scaffolds for Bone Engineering

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YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

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The impact of discrete compartments of a multi-compartment collagen–GAG scaffold on overall construct biophysical properties

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Transduction of mechanical and cytoskeletal cues by YAP and TAZ

(2012) Georg Halder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mediation of osteogenic differentiation of human mesenchymal stem cells on titanium surfaces by a Wnt-integrin feedback loop

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Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Prevalence, Complications, and Hospital Charges Associated With Use of Bone-Morphogenetic Proteins in Spinal Fusion Procedures

(2009) Kevin S. Cahill   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Characterization of mineralized collagen–glycosaminoglycan scaffolds for bone regeneration

(2008) Biraja P. Kanungo et al.   Acta Biomaterialia