Cells, scaffolds, and bioactive factors: Engineering strategies for improving regeneration following volumetric muscle loss

Self-aligned myofibers in 3D bioprinted extracellular matrix-based construct accelerate skeletal muscle function restoration

(2021) Hyeongjin Lee et al.   Applied Physics Reviews

Replace and repair: Biomimetic bioprinting for effective muscle engineering

(2021) Cooper Blake et al.   APL Bioengineering

Graft alignment impacts the regenerative response of skeletal muscle after volumetric muscle loss in a rat model

(2020) John Kim et al.   Acta Biomaterialia

Aligned nanofibers of decellularized muscle extracellular matrix for volumetric muscle loss

(2020) Krishna H. Patel et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function

(2020) Ji Hyun Kim et al.   Nature Communications

Skeletal Muscle Extracellular Matrix – What Do We Know About Its Composition, Regulation, and Physiological Roles? A Narrative Review

(2020) Robert Csapo et al.   Frontiers in Physiology

Elastin-Like Recombinamer Hydrogels for Improved Skeletal Muscle Healing Through Modulation of Macrophage Polarization

(2020) Arturo Ibáñez-Fonseca et al.   Frontiers in Bioengineering and Biotechnology

3D Printing and Bioprinting Nerve Conduits for Neural Tissue Engineering

(2020) Xiaoling Yu et al.   Polymers

Bioprinting of 3D in vitro skeletal muscle models: A review

(2020) Pei Zhuang et al.   MATERIALS & DESIGN

Intravital three-dimensional bioprinting

(2020) Anna Urciuolo et al.   Nature Biomedical Engineering

Towards stem cell therapies for skeletal muscle repair

(2020) Robert N. Judson et al.   npj Regenerative Medicine

Pre-innervated tissue-engineered muscle promotes a pro-regenerative microenvironment following volumetric muscle loss

(2020) Suradip Das et al.   Communications Biology

Engineering 3D skeletal muscle primed for neuromuscular regeneration following volumetric muscle loss

(2020) Jordana Gilbert-Honick et al.   BIOMATERIALS

A tissue engineering approach for repairing craniofacial volumetric muscle loss in a sheep following a 2, 4, and 6-month recovery

(2020) Brittany L. Rodriguez et al.   PLoS One

Smart ECM-Based Electrospun Biomaterials for Skeletal Muscle Regeneration

(2020) Sara Politi et al.   Nanomaterials

Pelvic floor muscle function recovery using biofabricated tissue constructs with neuromuscular junctions

(2020) Ji Hyun Kim et al.   Acta Biomaterialia

Repositioning Tacrolimus: Evaluation of the Effect of Short-Term Tacrolimus Treatment on Osteoprogenitor Cells and Primary Cells for Bone Regenerative Engineering

(2019) Edward O'Neill et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Biomaterial and stem cell-based strategies for skeletal muscle regeneration

(2019) Andrew Dunn et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Determination of a Critical Size Threshold for Volumetric Muscle Loss in the Mouse Quadriceps

(2019) Shannon Emily Anderson et al.   TISSUE ENGINEERING PART C-METHODS

Fortifying Angiogenesis in Ischemic Muscle with FGF9-Loaded Electrospun Poly(Ester Amide) Fibers

(2019) Somiraa S. Said et al.   Advanced Healthcare Materials

A 3D cell printed muscle construct with tissue-derived bioink for the treatment of volumetric muscle loss

(2019) Yeong-Jin Choi et al.   BIOMATERIALS

A novel decellularized skeletal muscle-derived ECM scaffolding system for in situ muscle regeneration

(2019) Hyeongjin Lee et al.   METHODS

Co-delivery of Wnt7a and muscle stem cells using synthetic bioadhesive hydrogel enhances murine muscle regeneration and cell migration during engraftment

(2019) Woojin M. Han et al.   Acta Biomaterialia

Peptide-Based Functional Biomaterials for Soft-Tissue Repair

(2019) Katsuhiro Hosoyama et al.   Frontiers in Bioengineering and Biotechnology

Therapeutic Approaches for Volumetric Muscle Loss Injury: A Systematic Review and Meta-Analysis

(2019) Sarah M. Greising et al.   TISSUE ENGINEERING PART B-REVIEWS

A porous collagen‐GAG scaffold promotes muscle regeneration following volumetric muscle loss injury

(2019) Adriana C. Panayi et al.   WOUND REPAIR AND REGENERATION

Bioprinting Vasculature: Materials, Cells and Emergent Techniques

(2019) Clarissa Tomasina et al.   Materials

Vascularized and Innervated Skeletal Muscle Tissue Engineering

(2019) Jordana Gilbert‐Honick et al.   Advanced Healthcare Materials

Engineering functional and histological regeneration of vascularized skeletal muscle

(2018) Jordana Gilbert-Honick et al.   BIOMATERIALS

A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration

(2018) Michael N. Wosczyna et al.   DEVELOPMENTAL CELL

Impact of volumetric muscle loss injury on persistent motoneuron axotomy

(2018) Benjamin T. Corona et al.   MUSCLE & NERVE

Volumetric muscle loss injury repair using in situ fibrin gel cast seeded with muscle-derived stem cells (MDSCs)

(2018) Nadine Matthias et al.   Stem Cell Research

Aligned Nanofibrillar Scaffolds for Controlled Delivery of Modified mRNA

(2018) Tatiana S. Zaitseva et al.   TISSUE ENGINEERING PART A

Stem Cells for Skeletal Muscle Tissue Engineering

(2018) Molly N. Pantelic et al.   TISSUE ENGINEERING PART B-REVIEWS

Extracellular matrix scaffolds for treatment of large volume muscle injuries: A review

(2018) Tiffany L. Sarrafian et al.   VETERINARY SURGERY

Robust inflammatory and fibrotic signaling following volumetric muscle loss: a barrier to muscle regeneration

(2018) Jacqueline Larouche et al.   Cell Death & Disease

Engineering human pluripotent stem cells into a functional skeletal muscle tissue

(2018) Lingjun Rao et al.   Nature Communications

Decellularised skeletal muscles allow functional muscle regeneration by promoting host cell migration

(2018) Anna Urciuolo et al.   Scientific Reports

Mesenchymal stem cells and extracellular matrix scaffold promote muscle regeneration by synergistically regulating macrophage polarization toward the M2 phenotype

(2018) Xinyu Qiu et al.   Stem Cell Research & Therapy

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering

(2018) Sara Martina Maffioletti et al.   Cell Reports

Large-Scale Expansion of Human iPSC-Derived Skeletal Muscle Cells for Disease Modeling and Cell-Based Therapeutic Strategies

(2018) Erik van der Wal et al.   Stem Cell Reports

3D Bioprinted Human Skeletal Muscle Constructs for Muscle Function Restoration

(2018) Ji Hyun Kim et al.   Scientific Reports

Tacrolimus- and Nerve Growth Factor-Treated Allografts for Neural Tissue Regeneration

(2018) Yixia Yin et al.   ACS Chemical Neuroscience

Functionalization of hyaluronic acid hydrogels with ECM-derived peptides to control myoblast behavior

(2018) Juan Martin Silva Garcia et al.   Acta Biomaterialia

The inflammasome in host response to biomaterials: Bridging inflammation and tissue regeneration

(2018) Daniela P. Vasconcelos et al.   Acta Biomaterialia

Adipose-derived Stem/Stromal Cells on Electrospun Fibrin Microfiber Bundles Enable Moderate Muscle Reconstruction in a Volumetric Muscle Loss Model

(2018) Jordana Gilbert-Honick et al.   CELL TRANSPLANTATION

Biomimetic sponges for regeneration of skeletal muscle following trauma

(2018) Gabriel J. Haas et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

The Effect of Laminin-111 Hydrogels on Muscle Regeneration in a Murine Model of Injury

(2018) Madison Marcinczyk et al.   TISSUE ENGINEERING PART A

IL-1β- and IL-4-polarized macrophages have opposite effects on adipogenesis of intramuscular fibro-adipogenic progenitors in humans

(2018) C. Moratal et al.   Scientific Reports

Divergent immune responses to synthetic and biological scaffolds

(2018) Kaitlyn Sadtler et al.   BIOMATERIALS

Chasing the recipe for a pro-regenerative immune system

(2017) James W. Godwin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cell and Growth Factor-Loaded Keratin Hydrogels for Treatment of Volumetric Muscle Loss in a Mouse Model

(2017) H.B. Baker et al.   TISSUE ENGINEERING PART A

Skeletal Myoblast-Seeded Vascularized Tissue Scaffolds in the Treatment of a Large Volumetric Muscle Defect in the Rat Biceps Femoris Muscle

(2017) Mon-Tzu Li et al.   TISSUE ENGINEERING PART A

The Scaffold Immune Microenvironment: Biomaterial-Mediated Immune Polarization in Traumatic and Nontraumatic Applications

(2017) Kaitlyn Sadtler et al.   TISSUE ENGINEERING PART A

Keratin Hydrogel Enhances In Vivo Skeletal Muscle Function in a Rat Model of Volumetric Muscle Loss

(2017) J.A. Passipieri et al.   TISSUE ENGINEERING PART A

Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss

(2017) Marco Quarta et al.   Nature Communications

Isolation of Murine Adipose Tissue-derived Microvascular Fragments as Vascularization Units for Tissue Engineering

(2017) Florian S. Frueh et al.   Jove-Journal of Visualized Experiments

Co-delivery of micronized urinary bladder matrix damps regenerative capacity of minced muscle grafts in the treatment of volumetric muscle loss injuries

(2017) Stephen M. Goldman et al.   PLoS One

Unwavering Pathobiology of Volumetric Muscle Loss Injury

(2017) Sarah M. Greising et al.   Scientific Reports

Anisotropic Materials for Skeletal-Muscle-Tissue Engineering

(2016) Soumen Jana et al.   ADVANCED MATERIALS

Mechanisms by which acellular biologic scaffolds promote functional skeletal muscle restoration

(2016) Stephen F. Badylak et al.   BIOMATERIALS

Regeneration techniques for bone-to-tendon and muscle-to-tendon interfaces reconstruction

(2016) Lucia Baldino et al.   BRITISH MEDICAL BULLETIN

Intravital Imaging Reveals Ghost Fibers as Architectural Units Guiding Myogenic Progenitors during Regeneration

(2016) Micah T. Webster et al.   Cell Stem Cell

A Porcine Urinary Bladder Matrix Does Not Recapitulate the Spatiotemporal Macrophage Response of Muscle Regeneration after Volumetric Muscle Loss Injury

(2016) Amit Aurora et al.   CELLS TISSUES ORGANS

Growth Factors for Skeletal Muscle Tissue Engineering

(2016) Brian C. Syverud et al.   CELLS TISSUES ORGANS

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Autologous Minced Muscle Grafts Improve Muscle Strength in a Porcine Model of Volumetric Muscle Loss Injury

(2016) Catherine L. Ward et al.   JOURNAL OF ORTHOPAEDIC TRAUMA

A 3D bioprinting system to produce human-scale tissue constructs with structural integrity

(2016) Hyun-Wook Kang et al.   NATURE BIOTECHNOLOGY

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells

(2016) K. Sadtler et al.   SCIENCE

Immunomodulation and Mobilization of Progenitor Cells by Extracellular Matrix Bioscaffolds for Volumetric Muscle Loss Treatment

(2016) Jenna L. Dziki et al.   TISSUE ENGINEERING PART A

Codelivery of Infusion Decellularized Skeletal Muscle with Minced Muscle Autografts Improved Recovery from Volumetric Muscle Loss Injury in a Rat Model

(2016) Benjamin Kasukonis et al.   TISSUE ENGINEERING PART A

Design, clinical translation and immunological response of biomaterials in regenerative medicine

(2016) Kaitlyn Sadtler et al.   Nature Reviews Materials

Volumetric Muscle Loss

(2016) Brian F. Grogan et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Battlefield Orthopaedic Injuries Cause the Majority of Long-term Disabilities

(2016) Jessica D. Cross et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Biomimetic scaffolds for regeneration of volumetric muscle loss in skeletal muscle injuries

(2015) Jonathan M. Grasman et al.   Acta Biomaterialia

Biomaterial-based delivery for skeletal muscle repair

(2015) Christine A. Cezar et al.   ADVANCED DRUG DELIVERY REVIEWS

Biomaterial strategies for engineering implants for enhanced osseointegration and bone repair

(2015) Rachit Agarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

Rapid release of growth factors regenerates force output in volumetric muscle loss injuries

(2015) Jonathan M. Grasman et al.   BIOMATERIALS

An acellular biologic scaffold does not regenerate appreciable de novo muscle tissue in rat models of volumetric muscle loss injury

(2015) Amit Aurora et al.   BIOMATERIALS

Volumetric muscle loss leads to permanent disability following extremity trauma

(2015) Benjamin T. Corona et al.   JOURNAL OF REHABILITATION RESEARCH AND DEVELOPMENT

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

(2015) Dario R Lemos et al.   NATURE MEDICINE

Therapeutic strategies for preventing skeletal muscle fibrosis after injury

(2015) Koyal Garg et al.   Frontiers in Pharmacology

Ex Vivo Expansion and In Vivo Self-Renewal of Human Muscle Stem Cells

(2015) Gregory W. Charville et al.   Stem Cell Reports

In situ regeneration of skeletal muscle tissue through host cell recruitment

(2014) Young Min Ju et al.   Acta Biomaterialia

Tissue Engineering and Regenerative Medicine Approaches to Enhance the Functional Response to Skeletal Muscle Injury

(2014) Brian M. Sicari et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Transplantation of devitalized muscle scaffolds is insufficient for appreciable de novo muscle fiber regeneration after volumetric muscle loss injury

(2014) Koyal Garg et al.   CELL AND TISSUE RESEARCH

Immune Modulation of Stem Cells and Regeneration

(2014) Arin B. Aurora et al.   Cell Stem Cell

Human Pluripotent Stem Cell Culture: Considerations for Maintenance, Expansion, and Therapeutics

(2014) Kevin G. Chen et al.   Cell Stem Cell

Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength

(2014) C. Florian Bentzinger et al.   JOURNAL OF CELL BIOLOGY

Volumetric muscle loss: Persistent functional deficits beyond frank loss of tissue

(2014) Koyal Garg et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Characterization and multilineage potential of cells derived from isolated microvascular fragments

(2014) Jennifer S. McDaniel et al.   JOURNAL OF SURGICAL RESEARCH

Minimally Invasive Approach to the Repair of Injured Skeletal Muscle With a Shape-memory Scaffold

(2014) Lin Wang et al.   MOLECULAR THERAPY

Preparing the ground for tissue regeneration: from mechanism to therapy

(2014) Stuart J Forbes et al.   NATURE MEDICINE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

An engineered muscle flap for reconstruction of large soft tissue defects

(2014) Y. Shandalov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Acellular Biologic Scaffold Promotes Skeletal Muscle Formation in Mice and Humans with Volumetric Muscle Loss

(2014) B. M. Sicari et al.   Science Translational Medicine

Engineered Skeletal Muscle Units for Repair of Volumetric Muscle Loss in the Tibialis Anterior Muscle of a Rat

(2014) Keith W. VanDusen et al.   TISSUE ENGINEERING PART A

Control of Scaffold Degradation in Tissue Engineering: A Review

(2014) Hongbo Zhang et al.   TISSUE ENGINEERING PART B-REVIEWS

Autologous minced muscle grafts: a tissue engineering therapy for the volumetric loss of skeletal muscle

(2013) B. T. Corona et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cellular dynamics in the muscle satellite cell niche

(2013) C Florian Bentzinger et al.   EMBO REPORTS

Muscle-derived decellularised extracellular matrix improves functional recovery in a rat latissimus dorsi muscle defect model

(2013) Xiaoyu K. Chen et al.   Journal of Plastic Reconstructive and Aesthetic Surgery

Satellite Cells and the Muscle Stem Cell Niche

(2013) Hang Yin et al.   PHYSIOLOGICAL REVIEWS

Sphingosine 1-phosphate receptor 3 regulates recruitment of anti-inflammatory monocytes to microvessels during implant arteriogenesis

(2013) Anthony O. Awojoodu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size

(2013) Qiu Li Loh et al.   TISSUE ENGINEERING PART B-REVIEWS

Extracellular matrix as an inductive scaffold for functional tissue reconstruction

(2013) Bryan N. Brown et al.   Translational Research

Satellite cells are essential for skeletal muscle regeneration: the cell on the edge returns centre stage

(2012) F. Relaix et al.   DEVELOPMENT

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Hyaluronic Acid Hydrogels for Biomedical Applications

(2011) Jason A. Burdick et al.   ADVANCED MATERIALS

Immune responses to implants – A review of the implications for the design of immunomodulatory biomaterials

(2011) Sandra Franz et al.   BIOMATERIALS

The role of multifunctional delivery scaffold in the ability of cultured myoblasts to promote muscle regeneration

(2011) Cristina Borselli et al.   BIOMATERIALS

Regeneration of skeletal muscle

(2011) Neill J. Turner et al.   CELL AND TISSUE RESEARCH

Design properties of hydrogel tissue-engineering scaffolds

(2011) Junmin Zhu et al.   Expert Review of Medical Devices

Immunogenicity of induced pluripotent stem cells

(2011) Tongbiao Zhao et al.   NATURE

Wnt7a–Fzd7 signalling directly activates the Akt/mTOR anabolic growth pathway in skeletal muscle

(2011) Julia von Maltzahn et al.   NATURE CELL BIOLOGY

Fibroblast Growth Factor-2–Overexpressing Myoblasts Encapsulated in Alginate Spheres Increase Proliferation, Reduce Apoptosis, Induce Adipogenesis, and Enhance Regeneration Following Skeletal Muscle Injury in Rats

(2011) Ioannis Stratos et al.   TISSUE ENGINEERING PART A

Electrospinning: A fascinating fiber fabrication technique

(2010) Nandana Bhardwaj et al.   BIOTECHNOLOGY ADVANCES

Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells

(2010) Yuta Mizuno et al.   FASEB JOURNAL

Growth factor delivery-based tissue engineering: general approaches and a review of recent developments

(2010) K. Lee et al.   Journal of the Royal Society Interface

Synergistic effects of FGF-2 and PDGF-BB on angiogenesis and muscle regeneration in rabbit hindlimb ischemia model

(2010) Jie Li et al.   MICROVASCULAR RESEARCH

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Human Induced Pluripotent Stem Cells Develop Teratoma More Efficiently and Faster Than Human Embryonic Stem Cells Regardless the Site of Injection

(2010) Ivan Gutierrez-Aranda et al.   STEM CELLS

Xenogeneic Extracellular Matrix as an Inductive Scaffold for Regeneration of a Functioning Musculotendinous Junction

(2010) Neill J. Turner et al.   TISSUE ENGINEERING PART A

Wnt7a Activates the Planar Cell Polarity Pathway to Drive the Symmetric Expansion of Satellite Stem Cells

(2009) Fabien Le Grand et al.   Cell Stem Cell

Efficient Delivery of Human Single Fiber-Derived Muscle Precursor Cells via Biocompatible Scaffold

(2009) Luisa Boldrin et al.   CELL TRANSPLANTATION

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers

(2008) I-Chien Liao et al.   Cellular and Molecular Bioengineering

Engineering of multifunctional gels integrating highly efficient growth factor delivery with endothelial cell transplantation

(2008) Steven M. Jay et al.   FASEB JOURNAL

Isolation of a slowly adhering cell fraction containing stem cells from murine skeletal muscle by the preplate technique

(2008) Burhan Gharaibeh et al.   Nature Protocols

Vascularization in tissue engineering

(2008) Jeroen Rouwkema et al.   TRENDS IN BIOTECHNOLOGY