Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy

(2014) Sherry Dadgar et al.   JOURNAL OF CELL BIOLOGY

Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis

(2014) Luca Richeldi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

(2013) Rémi Mounier et al.   Cell Metabolism

Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease

(2013) Rafael Kramann et al.   JOURNAL OF PATHOLOGY

Macrophage Plasticity and the Role of Inflammation in Skeletal Muscle Repair

(2013) Yacine Kharraz et al.   MEDIATORS OF INFLAMMATION

A new model of experimental fibrosis in hindlimb skeletal muscle of adult mdx mouse mimicking muscular dystrophy

(2012) Isabelle Desguerre et al.   MUSCLE & NERVE

An Abundant Tissue Macrophage Population in the Adult Murine Heart with a Distinct Alternatively-Activated Macrophage Profile

(2012) Alexander R. Pinto et al.   PLoS One

Differential Ly-6C expression identifies the recruited macrophage phenotype, which orchestrates the regression of murine liver fibrosis

(2012) P. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functionally Convergent White Adipogenic Progenitors of Different Lineages Participate in a Diffused System Supporting Tissue Regeneration

(2012) Dario R. Lemos et al.   STEM CELLS

Overexpression of cellular repressor of E1A-stimulated genes inhibits TNF-α-induced apoptosis via NF-κB in mesenchymal stem cells

(2011) Cheng-Fei Peng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib

(2011) Yuqing Liu et al.   JOURNAL OF HEPATOLOGY

Comment on "Experimental Arthritis Triggers Periodontal Disease in Mice: Involvement of TNF-  and the Oral Microbiota"

(2011) A. A. Kruglov et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal stem cell–based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α

(2011) Yi Liu et al.   NATURE MEDICINE

Effect of Nilotinib on Bleomycin-Induced Acute Lung Injury and Pulmonary Fibrosis in Mice

(2011) Chin Kook Rhee et al.   RESPIRATION

Aberrant repair and fibrosis development in skeletal muscle

(2011) Christopher J Mann et al.   Skeletal Muscle

Regulatory interactions between muscle and the immune system during muscle regeneration

(2010) James G. Tidball et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury

(2010) Haiyan Lu et al.   FASEB JOURNAL

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Imatinib Treatment for Idiopathic Pulmonary Fibrosis

(2009) Craig E. Daniels et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Muscle resident macrophages control the immune cell reaction in a mouse model of notexin-induced myoinjury

(2009) Madly Brigitte et al.   ARTHRITIS AND RHEUMATISM

Imatinib attenuates skeletal muscle dystrophy in mdx mice

(2009) Ping Huang et al.   FASEB JOURNAL

A CREB-C/EBP  cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair

(2009) D. Ruffell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interstitial pneumonitis associated with infliximab therapy without methotrexate treatment

(2009) Hirofumi Taki et al.   RHEUMATOLOGY INTERNATIONAL

The controversial role of tumor necrosis factor α in fibrotic diseases

(2008) Jörg H. W. Distler et al.   ARTHRITIS AND RHEUMATISM

Dual and Beneficial Roles of Macrophages During Skeletal Muscle Regeneration

(2008) Bénédicte Chazaud et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Fibrinogen drives dystrophic muscle fibrosis via a TGF /alternative macrophage activation pathway

(2008) B. Vidal et al.   GENES & DEVELOPMENT

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS