Genetic liability for prescription opioid use and risk of cardiovascular diseases: a multivariable Mendelian randomization study

Mendelian Randomization Study of Obesity and Cerebrovascular Disease

(2020) Sandro Marini et al.   ANNALS OF NEUROLOGY

Association of smoking with coronary artery disease and myocardial infarction: A Mendelian randomization study

(2020) Yunlong Lu et al.   European Journal of Preventive Cardiology

Statistical inference in two-sample summary-data Mendelian randomization using robust adjusted profile score

(2020) Qingyuan Zhao et al.   ANNALS OF STATISTICS

Physical exercise and chronic pain in university students

(2020) Michael Grasdalsmoen et al.   PLoS One

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

(2020) Ben Brumpton et al.   Nature Communications

Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders

(2020) Daniel B. Rosoff et al.   JAMA Psychiatry

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

(2019) Mengzhen Liu et al.   NATURE GENETICS

Meta-Analysis and Mendelian randomization: A review

(2019) Jack Bowden et al.   Research Synthesis Methods

Current perspectives on the opioid crisis in the US healthcare system

(2019) Nicoleta Stoicea et al.   MEDICINE

Global Updates on Cardiovascular Disease Mortality Trends and Attribution of Traditional Risk Factors

(2019) Ram Jagannathan et al.   Current Diabetes Reports

Exploring Unconventional Risk-Factors for Cardiovascular Diseases: Has Opioid Therapy Been Overlooked?

(2019) Oluwabunmi Ogungbe et al.   International Journal of Environmental Research and Public Health

Depression increases the genetic susceptibility to high body mass index: Evidence from UK Biobank

(2019) Anwar Mulugeta et al.   DEPRESSION AND ANXIETY

Mechanistic insights into δ-opioid-induced cardioprotection: Involvement of caveolin translocation to the mitochondria

(2019) Jia-Wan Wang et al.   LIFE SCIENCES

Association of tramadol with risk of myocardial infarction among patients with osteoarthritis

(2019) J. Wei et al.   OSTEOARTHRITIS AND CARTILAGE

Opioids in Cardiovascular Disease: Therapeutic Options

(2018) Hemangi Rawal et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

(2018) Rainer Malik et al.   NATURE GENETICS

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

(2018) Evangelos Evangelou et al.   NATURE GENETICS

A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization

(2017) Jack Bowden et al.   STATISTICS IN MEDICINE

Orienting the causal relationship between imprecisely measured traits using GWAS summary data

(2017) Gibran Hemani et al.   PLoS Genetics

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

A Proactive Response to Prescription Opioid Abuse

(2016) Robert M. Califf et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Effectiveness and Risks of Long-Term Opioid Therapy for Chronic Pain: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop

(2015) Roger Chou et al.   ANNALS OF INTERNAL MEDICINE

Opioid receptors and cardioprotection - ‘opioidergic conditioning’ of the heart

(2015) John P Headrick et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mendelian randomization analysis supports the causal role of dysglycaemia and diabetes in the risk of coronary artery disease

(2015) Stephanie Ross et al.   EUROPEAN HEART JOURNAL

Mendelian randomization studies: a review of the approaches used and the quality of reporting

(2015) A. G. C. Boef et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome

(2015) Fabiola Del Greco M et al.   STATISTICS IN MEDICINE

The association between chronic pain and obesity

(2015) Akiko Okifuji et al.   Journal of Pain Research

The presence of mu-, delta-, and kappa-opioid receptors in human heart tissue

(2014) Piotr Sobanski et al.   HEART AND VESSELS

Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome

(2014) S. Burgess   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Efficient Design for Mendelian Randomization Studies: Subsample and 2-Sample Instrumental Variable Estimators

(2013) B. L. Pierce et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Observational research — opportunities and limitations

(2013) Edward J. Boyko   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Opioid use for noncancer pain and risk of myocardial infarction amongst adults

(2013) L. Li et al.   JOURNAL OF INTERNAL MEDICINE

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Nutrition and Eating Behavior in Patients With Chronic Pain Receiving Long-Term Opioid Therapy

(2013) Alec L. Meleger et al.   PM&R

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Coronary heart disease outcomes among chronic opioid and cyclooxygenase-2 users compared with a general population cohort

(2011) Wendy J. Carman et al.   PHARMACOEPIDEMIOLOGY AND DRUG SAFETY

The Effects of Opioids and Opioid Analogs on Animal and Human Endocrine Systems

(2010) Cassidy Vuong et al.   ENDOCRINE REVIEWS

Opioid receptors in the gastrointestinal tract

(2009) Peter Holzer   REGULATORY PEPTIDES