Mendelian randomization studies: a review of the approaches used and the quality of reporting

C-reactive protein polymorphisms are associated with the cortisol awakening response in basal conditions in human subjects

(2016) Gerthe Veen et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Methodological Challenges in Mendelian Randomization

(2014) Tyler J. VanderWeele et al.   EPIDEMIOLOGY

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Arsenic metabolism efficiency has a causal role in arsenic toxicity: Mendelian randomization and gene-environment interaction

(2014) B. L. Pierce et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Role of obesity on all-cause mortality in whites with type 2 diabetes from Italy

(2013) R. Di Paola et al.   ACTA DIABETOLOGICA

Donor Surfactant Protein D (SP-D) Polymorphisms Are Associated With Lung Transplant Outcome

(2013) B. Aramini et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Elevated C-Reactive Protein, Depression, Somatic Diseases, and All-Cause Mortality: A Mendelian Randomization Study

(2013) Marie Kim Wium-Andersen et al.   BIOLOGICAL PSYCHIATRY

Adhesion molecules, endothelin-1 and lung function in seven population-based cohorts

(2013) E. C. Oelsner et al.   BIOMARKERS

The causal effect of red blood cell folate on genome-wide methylation in cord blood: a Mendelian randomization approach

(2013) Alexandra M Binder et al.   BMC BIOINFORMATICS

Association of homocysteine with type 2 diabetes: a meta-analysis implementing Mendelian randomization approach

(2013) Tao Huang et al.   BMC GENOMICS

Using Genetic Proxies for Lifecourse Sun Exposure to Assess the Causal Relationship of Sun Exposure with Circulating Vitamin D and Prostate Cancer Risk

(2013) C. Bonilla et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Elevated Remnant Cholesterol Causes Both Low-Grade Inflammation and Ischemic Heart Disease, Whereas Elevated Low-Density Lipoprotein Cholesterol Causes Ischemic Heart Disease Without Inflammation

(2013) Anette Varbo et al.   CIRCULATION

Association Between C677T Polymorphism of Methylene Tetrahydrofolate Reductase and Congenital Heart Disease

(2013) Chrysovalanto Mamasoula et al.   Circulation-Cardiovascular Genetics

Vitamin D and Mortality: A Mendelian Randomization Study

(2013) O. Trummer et al.   CLINICAL CHEMISTRY

Causal relationship between body mass index and fetuin-A level in the asian population: a bidirectional mendelian randomization study

(2013) Ammarin Thakkinstian et al.   CLINICAL ENDOCRINOLOGY

The Association Between Circulating Lipoprotein(a) and Type 2 Diabetes: Is It Causal?

(2013) Z. Ye et al.   DIABETES

Mendelian Randomization Studies Do Not Support a Causal Role for Reduced Circulating Adiponectin Levels in Insulin Resistance and Type 2 Diabetes

(2013) H. Yaghootkar et al.   DIABETES

Genetically Elevated Fetuin-A Levels, Fasting Glucose Levels, and Risk of Type 2 Diabetes: The Cardiovascular Health Study

(2013) M. K. Jensen et al.   DIABETES CARE

Mendelian randomization in health research: Using appropriate genetic variants and avoiding biased estimates

(2013) Amy E. Taylor et al.   Economics & Human Biology

A causal role for circulating miR-34b in osteosarcoma

(2013) Q. Tian et al.   EJSO

Reporting Instrumental Variable Analyses

(2013) Anna G. C. Boef et al.   EPIDEMIOLOGY

Issues in the Reporting and Conduct of Instrumental Variable Studies

(2013) Neil M. Davies et al.   EPIDEMIOLOGY

Commentary

(2013) Sonja A. Swanson et al.   EPIDEMIOLOGY

Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study

(2013) D. A. Lawlor et al.   EUROPEAN HEART JOURNAL

The relevance of the association between inflammation and atrial fibrillation

(2013) Josep M. Alegret et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Investigating the causal effect of vitamin D on serum adiponectin using a mendelian randomization approach

(2013) L L N Husemoen et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Vitamin D and high blood pressure: causal association or epiphenomenon?

(2013) Setor K. Kunutsor et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Enrichment of vitamin D response elements in RA-associated loci supports a role for vitamin D in the pathogenesis of RA

(2013) A Yarwood et al.   GENES AND IMMUNITY

Elevated body mass index as a causal risk factor for symptomatic gallstone disease: A Mendelian randomization study

(2013) Stefan Stender et al.   HEPATOLOGY

Genetically predicted testosterone and cardiovascular risk factors in men: a Mendelian randomization analysis in the Guangzhou Biobank Cohort Study

(2013) Jie Zhao et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Prenatal alcohol exposure and offspring cognition and school performance. A ‘Mendelian randomization’ natural experiment

(2013) Luisa Zuccolo et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The causal effect of malaria on stunting: a Mendelian randomization and matching approach

(2013) Hyunseung Kang et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Use of allele scores as instrumental variables for Mendelian randomization

(2013) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetic taste blindness to bitter and body composition in childhood: a Mendelian randomization design

(2013) S H Bouthoorn et al.   INTERNATIONAL JOURNAL OF OBESITY

Prenatal alcohol exposure and childhood atopic disease: A Mendelian randomization approach

(2013) Seif O. Shaheen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mendelian Randomization Analysis of the Effect of Maternal Homocysteine During Pregnancy, as Represented by Maternal MTHFR C677T Genotype, on Birth Weight

(2013) Hye Ah Lee et al.   JOURNAL OF EPIDEMIOLOGY

Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis

(2013) S. Stender et al.   JOURNAL OF INTERNAL MEDICINE

Ceruloplasmin and atrial fibrillation: evidence of causality from a population-based Mendelian randomization study

(2013) S. Adamsson Eryd et al.   JOURNAL OF INTERNAL MEDICINE

Secretory Phospholipase A 2 -IIA and Cardiovascular Disease

(2013) Michael V. Holmes et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Elevated Lipoprotein(a) and Risk of Aortic Valve Stenosis in the General Population

(2013) Pia R. Kamstrup et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function

(2013) Kim Hughes et al.   KIDNEY INTERNATIONAL

The triangular association of ADH1B genetic polymorphism, alcohol consumption and the risk of depression in older men

(2013) O P Almeida et al.   MOLECULAR PSYCHIATRY

Abdominal obesity and lower gray matter volume: a Mendelian randomization study

(2013) Stéphanie Debette et al.   NEUROBIOLOGY OF AGING

Genetic Associations with Valvular Calcification and Aortic Stenosis

(2013) George Thanassoulis et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dissecting the relationship between high-sensitivity serum C-reactive protein and increased fracture risk: the Rotterdam Study

(2013) L. Oei et al.   OSTEOPOROSIS INTERNATIONAL

An inherited variant in the gene coding for vitamin D-binding protein and survival from cutaneous melanoma: a BioGenoMEL study

(2013) John R. Davies et al.   Pigment Cell & Melanoma Research

Vitamin D Status, Filaggrin Genotype, and Cardiovascular Risk Factors: A Mendelian Randomization Approach

(2013) Tea Skaaby et al.   PLoS One

Causal Relationship between Adiponectin and Metabolic Traits: A Mendelian Randomization Study in a Multiethnic Population

(2013) Andrew Mente et al.   PLoS One

Association between CFH Y402H Polymorphism and Age Related Macular Degeneration in North Indian Cohort

(2013) Neel Kamal Sharma et al.   PLoS One

Moderate Alcohol Use and Cardiovascular Disease from Mendelian Randomization

(2013) Shiu Lun Au Yeung et al.   PLoS One

Elevated C-Reactive Protein Associated With Late- and Very-Late-Onset Schizophrenia in the General Population: A Prospective Study

(2013) Marie Kim Wium-Andersen et al.   SCHIZOPHRENIA BULLETIN

Identifying the odds ratio estimated by a two-stage instrumental variable analysis with a logistic regression model

(2013) Stephen Burgess et al.   STATISTICS IN MEDICINE

Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts

(2013) T. M. Palmer et al.   BMJ-British Medical Journal

Serum Iron Levels and the Risk of Parkinson Disease: A Mendelian Randomization Study

(2013) Irene Pichler et al.   PLOS MEDICINE

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

(2013) Tove Fall et al.   PLOS MEDICINE

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts

(2013) Karani S. Vimaleswaran et al.   PLOS MEDICINE

Extreme Bilirubin Levels as a Causal Risk Factor for Symptomatic Gallstone Disease

(2013) Stefan Stender et al.   JAMA Internal Medicine

Lipoprotein(a) concentrations, isoform size, and risk of type 2 diabetes: a Mendelian randomisation study

(2013) Pia R Kamstrup et al.   Lancet Diabetes & Endocrinology

PPARG2 Pro12Ala and ADAMTS9 rs4607103 as “insulin resistance loci” and “insulin secretion loci” in Italian individuals. The GENFIEV study and the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 4

(2012) M. Trombetta et al.   ACTA DIABETOLOGICA

Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population

(2012) Wei Gan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease mortality among 6000 US adults

(2012) Quanhe Yang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Evaluation of Moderate Alcohol Use and Cognitive Function Among Men Using a Mendelian Randomization Design in the Guangzhou Biobank Cohort Study

(2012) S. L. Au Yeung et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Elevated Fibrinogen Levels Are Associated with Risk of Pulmonary Embolism, but Not with Deep Venous Thrombosis

(2012) Jolanta Klovaite et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Genetic Evidence That Lipoprotein(a) Associates With Atherosclerotic Stenosis Rather Than Venous Thrombosis

(2012) Pia R. Kamstrup et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Associations between serum uric acid and markers of subclinical atherosclerosis in young adults. The cardiovascular risk in Young Finns study

(2012) Mervi Oikonen et al.   ATHEROSCLEROSIS

Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference

(2012) Patrick F McArdle et al.   BMC Cardiovascular Disorders

Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children

(2012) Carolina Bonilla et al.   BMC Medical Genetics

Causal Relevance of Blood Lipid Fractions in the Development of Carotid Atherosclerosis

(2012) Sonia Shah et al.   Circulation-Cardiovascular Genetics

Causal inference of the effect of adiposity on bone mineral density in adults

(2012) Daruneewan Warodomwichit et al.   CLINICAL ENDOCRINOLOGY

A Prospective Study of Leukocyte Telomere Length and Risk of Type 2 Diabetes in Postmenopausal Women

(2012) N.-c. Y. You et al.   DIABETES

Evidence of a Causal Relationship Between Adiponectin Levels and Insulin Sensitivity: A Mendelian Randomization Study

(2012) H. Gao et al.   DIABETES

Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis

(2012) M. Islam et al.   DIABETOLOGIA

Traits of ADHD and autism in girls with a twin brother: a Mendelian randomization study

(2012) Jørn Attermann et al.   EUROPEAN CHILD & ADOLESCENT PSYCHIATRY

Interleukin-6 receptor pathways in abdominal aortic aneurysm

(2012) Seamus C. Harrison et al.   EUROPEAN HEART JOURNAL

Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction

(2012) Anders Berg Jørgensen et al.   EUROPEAN HEART JOURNAL

Pancreatic beta-cell function and type 2 diabetes risk: quantify the causal effect using a Mendelian randomization approach based on meta-analyses

(2012) Yiqing Song et al.   HUMAN MOLECULAR GENETICS

Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

(2012) Carlos Cruchaga et al.   HUMAN MOLECULAR GENETICS

Caffeine intake and CYP1A2 variants associated with high caffeine intake protect non-smokers from hypertension

(2012) Idris Guessous et al.   HUMAN MOLECULAR GENETICS

Genetic variation in thelactasegene, dairy product intake and risk for prostate cancer in the European prospective investigation into cancer and nutrition

(2012) Ruth C. Travis et al.   INTERNATIONAL JOURNAL OF CANCER

Association of interleukin-6 circulating levels with coronary artery disease: A meta-analysis implementing mendelian randomization approach

(2012) Wenquan Niu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses

(2012) Stefan Stender et al.   JOURNAL OF HEPATOLOGY

Genetically elevated levels of circulating triglycerides and brachial–ankle pulse wave velocity in a Chinese population

(2012) W-M Yao et al.   JOURNAL OF HUMAN HYPERTENSION

Nonfasting Glucose, Ischemic Heart Disease, and Myocardial Infarction

(2012) Marianne Benn et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease

(2012) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Remnant Cholesterol as a Causal Risk Factor for Ischemic Heart Disease

(2012) Anette Varbo et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Instrumental Variable Estimators for Binary Outcomes

(2012) Paul S. Clarke et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

Sex hormone-binding globulin levels are not causally related to venous thrombosis risk in women not using hormonal contraceptives

(2012) B.H. STEGEMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

(2012)   LANCET

Serum Uric Acid and Adiposity: Deciphering Causality Using a Bidirectional Mendelian Randomization Approach

(2012) Tanica Lyngdoh et al.   PLoS One

Instrumental Variable Estimation of the Causal Effect of Plasma 25-Hydroxy-Vitamin D on Colorectal Cancer Risk: A Mendelian Randomization Analysis

(2012) Evropi Theodoratou et al.   PLoS One

A Comparison of Three Methods of Mendelian Randomization when the Genetic Instrument, the Risk Factor and the Outcome Are All Binary

(2012) Philippe Vuistiner et al.   PLoS One

Association of the European Lactase Persistence Variant (LCT-13910 C>T Polymorphism) with Obesity in the Canary Islands

(2012) Ricardo Almon et al.   PLoS One

Vitamin B-12 Status during Pregnancy and Child’s IQ at Age 8: A Mendelian Randomization Study in the Avon Longitudinal Study of Parents and Children

(2012) Carolina Bonilla et al.   PLoS One

The causal role of smoking in anxiety and depression: a Mendelian randomization analysis of the HUNT study

(2012) J. H. Bjørngaard et al.   PSYCHOLOGICAL MEDICINE

The Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach

(2012) Børge G. Nordestgaard et al.   PLOS MEDICINE

Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias

(2012) Robert Clarke et al.   PLOS MEDICINE

Exploring the relationship between maternal iron status and offspring’s blood pressure and adiposity: a Mendelian randomization study

(2012) Nisreen Alwan et al.   Clinical Epidemiology

Examining Overweight and Obesity as Risk Factors for Common Mental Disorders Using Fat Mass and Obesity-Associated (FTO) Genotype-Instrumented Analysis: The Whitehall II Study, 1985-2004

(2011) M. Kivimaki et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Instrumental Variable Estimation of Causal Risk Ratios and Causal Odds Ratios in Mendelian Randomization Analyses

(2011) T. M. Palmer et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Mendelian Randomization Studies Do Not Support a Role for Raised Circulating Triglyceride Levels Influencing Type 2 Diabetes, Glucose Levels, or Insulin Resistance

(2011) N. Maneka G. De Silva et al.   DIABETES

No evidence for a causal link between uric acid and type 2 diabetes: a Mendelian randomisation approach

(2011) R. Pfister et al.   DIABETOLOGIA

Relationship between ADIPOQ gene, circulating high molecular weight adiponectin and albuminuria in individuals with normal kidney function: evidence from a family-based study

(2011) C. Menzaghi et al.   DIABETOLOGIA

Association of an apolipoprotein E polymorphism with circulating cholesterols and hypertension: a meta-based Mendelian randomization analysis

(2011) Wenquan Niu et al.   HYPERTENSION RESEARCH

C-reactive protein haplotypes and dispositional optimism in obese and nonobese elderly subjects

(2011) Nathaly Rius-Ottenheim et al.   INFLAMMATION RESEARCH

LCAT, HDL Cholesterol and Ischemic Cardiovascular Disease: A Mendelian Randomization Study of HDL Cholesterol in 54,500 Individuals

(2011) Christiane L. Haase et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53 221 adults

(2011) Debbie A. Lawlor et al.   JOURNAL OF INTERNAL MEDICINE

Low-Density Lipoprotein Cholesterol and the Risk of Cancer: A Mendelian Randomization Study

(2011) Marianne Benn et al.   JNCI-Journal of the National Cancer Institute

Genotype-based changes in serum uric acid affect blood pressure

(2011) Afshin Parsa et al.   KIDNEY INTERNATIONAL

Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study

(2011) J Anthony G Scott et al.   LANCET

Low cholesterol in dialysis patients--causal factor for mortality or an effect of confounding?

(2011) M. Chmielewski et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Type II Secretory Phospholipase A2 and Prognosis in Patients with Stable Coronary Heart Disease: Mendelian Randomization Study

(2011) Lutz P. Breitling et al.   PLoS One

Smoking Is Associated with, but Does Not Cause, Depressed Mood in Pregnancy – A Mendelian Randomization Study

(2011) Sarah J. Lewis et al.   PLoS One

Mendelian Randomization Study of Interleukin-6 in Chronic Obstructive Pulmonary Disease

(2011) Yannick M.T.A. van Durme et al.   RESPIRATION

Genes Associated With Adult Cerebral Venous Thrombosis

(2011) Thomas Marjot et al.   STROKE

Mendelian Randomization Study of B-Type Natriuretic Peptide and Type 2 Diabetes: Evidence of Causal Association from Population Studies

(2011) Roman Pfister et al.   PLOS MEDICINE

Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)–Potsdam Study

(2010) Janine Kröger et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Use of A Mendelian Randomization Approach to Assess the Causal Relation of  -Glutamyltransferase with Blood Pressure and Serum Insulin Levels

(2010) D. Conen et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

C-Reactive Protein and Risk of Venous Thromboembolism in the General Population

(2010) Jeppe Zacho et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PLA2G7 Genotype, Lipoprotein-Associated Phospholipase A 2 Activity, and Coronary Heart Disease Risk in 10 494 Cases and 15 624 Controls of European Ancestry

(2010) Juan P. Casas et al.   CIRCULATION

The CRP genotype, serum levels and lung function in men: the Caerphilly Prospective Study

(2010) Charlotte E. Bolton et al.   CLINICAL SCIENCE

Alcohol ingestion and colorectal neoplasia: a meta-analysis based on a Mendelian randomization approach

(2010) J. Wang et al.   Colorectal Disease

Association of a Fasting Glucose Genetic Risk Score With Subclinical Atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study

(2010) L. J. Rasmussen-Torvik et al.   DIABETES

C-reactive protein and all-cause mortality--the Copenhagen City Heart Study

(2010) J. Zacho et al.   EUROPEAN HEART JOURNAL

C-reactive protein-associated genetic variants and cancer risk: Findings from FINRISK 1992, FINRISK 1997 and Health 2000 studies

(2010) Katriina Heikkilä et al.   EUROPEAN JOURNAL OF CANCER

Genetic Susceptibility to Type 2 Diabetes Is Associated with Reduced Prostate Cancer Risk

(2010) Brandon L. Pierce et al.   HUMAN HEREDITY

Common CD36 SNPs reduce protein expression and may contribute to a protective atherogenic profile

(2010) Latisha Love-Gregory et al.   HUMAN MOLECULAR GENETICS

Conventional and Mendelian randomization analyses suggest no association between lipoprotein(a) and early atherosclerosis: the Young Finns Study

(2010) Mika Kivimäki et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization

(2010) N J Timpson et al.   INTERNATIONAL JOURNAL OF OBESITY

Does Elevated C-Reactive Protein Increase Atrial Fibrillation Risk?

(2010) Sarah C.W. Marott et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

C-Reactive Protein and the Risk of Cancer: A Mendelian Randomization Study

(2010) Kristine H. Allin et al.   JNCI-Journal of the National Cancer Institute

Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies

(2010)   LANCET

Is fetuin-A a mortality risk factor in dialysis patients or a mere risk marker? A Mendelian randomization approach

(2010) M. Verduijn et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Causal Relationship of Susceptibility Genes to Ischemic Stroke: Comparison to Ischemic Heart Disease and Biochemical Determinants

(2010) Paul Bentley et al.   PLoS One

Assumptions of IV Methods for Observational Epidemiology

(2010) Vanessa Didelez et al.   STATISTICAL SCIENCE

C reactive protein and chronic obstructive pulmonary disease: a Mendelian randomisation approach

(2010) M. Dahl et al.   THORAX

Usefulness of Mendelian Randomization in Observational Epidemiology

(2010) Murielle Bochud et al.   International Journal of Environmental Research and Public Health

Relation of Age-related Cataract With Obesity and Obesity Genes in an Asian Population

(2009) L. S. Lim et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Apolipoprotein E Genotype, Plasma Cholesterol, and Cancer: A Mendelian Randomization Study

(2009) S. Trompet et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Influence of Methylenetetrahydrofolate Reductase Gene Polymorphisms on Homocysteine Concentrations after Nitrous Oxide Anesthesia

(2009) Peter Nagele et al.   ANESTHESIOLOGY

Aldehyde Dehydrogenase 2 and Head and Neck Cancer: A Meta-analysis Implementing a Mendelian Randomization Approach

(2009) S. Boccia et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Association of AHSG Gene Polymorphisms With Fetuin-A Plasma Levels and Cardiovascular Diseases in the EPIC-Potsdam Study

(2009) Eva Fisher et al.   Circulation-Cardiovascular Genetics

Lack of association between the MTHFR (C677T) polymorphism and atopic disease

(2009) Betina Heinsbaek Thuesen et al.   Clinical Respiratory Journal

Circulating β-carotene levels and type 2 diabetes—cause or effect?

(2009) J. R. B. Perry et al.   DIABETOLOGIA

Associations between lactase persistence and the metabolic syndrome in a cross-sectional study in the Canary Islands

(2009) Ricardo Almon et al.   EUROPEAN JOURNAL OF NUTRITION

Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk

(2009) Fotios Drenos et al.   HUMAN MOLECULAR GENETICS

Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes

(2009) John R.B. Perry et al.   HUMAN MOLECULAR GENETICS

Does Greater Adiposity Increase Blood Pressure and Hypertension Risk?

(2009) Nicholas J. Timpson et al.   HYPERTENSION

Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype

(2009) P. Brennan et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The paraoxonase (PON1) Q192R polymorphism is not associated with poor health status or depression in the ELSA or INCHIANTI studies

(2009) N. E Rice et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetically Elevated Lipoprotein(a) and Increased Risk of Myocardial Infarction

(2009) Pia R. Kamstrup   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease

(2009) Paul Elliott   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association between C-Reactive Protein and Adiposity in Women

(2009) Murielle Bochud et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach

(2009) Paul Welsh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

RBP4variants are significantly associated with plasma RBP4 levels and hypertriglyceridemia risk in Chinese Hans

(2009) Ying Wu et al.   JOURNAL OF LIPID RESEARCH

Polymorphisms of the insulin receptor and the insulin receptor substrates genes in polycystic ovary syndrome: A Mendelian randomization meta-analysis

(2009) Anastasios Ioannidis et al.   MOLECULAR GENETICS AND METABOLISM

Sex Hormone–Binding Globulin and Risk of Type 2 Diabetes in Women and Men

(2009) Eric L. Ding et al.   NEW ENGLAND JOURNAL OF MEDICINE

Instrumental Variable Analysis for Estimation of Treatment Effects With Dichotomous Outcomes

(2008) J. A. Rassen et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes

(2008) S. Rafiq et al.   DIABETOLOGIA

Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study

(2008) M. Kivimaki et al.   EUROPEAN HEART JOURNAL

Systemic inflammation, genetic susceptibility and lung function

(2008) J. Sunyer et al.   EUROPEAN RESPIRATORY JOURNAL

Serum cholesterol, apolipoprotein E genotype and depressive symptoms in elderly European men: The FINE study

(2008) Erik J. Giltay et al.   JOURNAL OF AFFECTIVE DISORDERS

How Does Body Fat Influence Bone Mass in Childhood? A Mendelian Randomization Approach

(2008) Nicholas J Timpson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Association of C-Reactive Protein and CRP Genotype with Coronary Heart Disease: Findings from Five Studies with 4,610 Cases amongst 18,637 Participants

(2008) Debbie A. Lawlor et al.   PLoS One

Lifelong Reduction of LDL-Cholesterol Related to a Common Variant in the LDL-Receptor Gene Decreases the Risk of Coronary Artery Disease—A Mendelian Randomisation Study

(2008) Patrick Linsel-Nitschke et al.   PLoS One

Does High C-reactive Protein Concentration Increase Atherosclerosis? The Whitehall II Study

(2008) Mika Kivimäki et al.   PLoS One

Inflammation, Insulin Resistance, and Diabetes—Mendelian Randomization Using CRP Haplotypes Points Upstream

(2008) Eric J Brunner et al.   PLOS MEDICINE

Exploring the Developmental Overnutrition Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable

(2008) Debbie A Lawlor et al.   PLOS MEDICINE

Alcohol Intake and Blood Pressure: A Systematic Review Implementing a Mendelian Randomization Approach

(2008) Lina Chen et al.   PLOS MEDICINE

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE