Multistage-Responsive Nanocomplexes Attenuate Ulcerative Colitis by Improving the Accumulation and Distribution of Oral Nucleic Acid Drugs in the Colon

Targeting the epigenome in in-stent restenosis: from mechanisms to therapy

(2021) Xi Yang et al.   Molecular Therapy-Nucleic Acids

Nicotine: Regulatory roles and mechanisms in atherosclerosis progression

(2021) Xiuxiu Fu et al.   FOOD AND CHEMICAL TOXICOLOGY

Nanomedicine-based delivery strategies for nucleic acid gene inhibitors in inflammatory diseases

(2021) Elias Fattal et al.   ADVANCED DRUG DELIVERY REVIEWS

Systemic Inflammation in Preclinical Ulcerative Colitis

(2021) Daniel Bergemalm et al.   GASTROENTEROLOGY

Dynamic properties of the intestinal ecosystem call for combination therapies, targeting inflammation and microbiota, in ulcerative colitis

(2021) Maarten van de Guchte et al.   GASTROENTEROLOGY

Deliver the promise: RNAs as a new class of molecular entities for therapy and vaccination

(2021) Ai-Ming Yu et al.   PHARMACOLOGY & THERAPEUTICS

The regulatory roles of aminoacyl-tRNA synthetase in cardiovascular disease

(2021) Yulin Zou et al.   Molecular Therapy-Nucleic Acids

Colon‐Targeted Adhesive Hydrogel Microsphere for Regulation of Gut Immunity and Flora

(2021) Hua Liu et al.   Advanced Science

Extracellular Vesicles as Natural Delivery Carriers Regulate Oxidative Stress Under Pathological Conditions

(2021) Hongzhao Qi et al.   Frontiers in Bioengineering and Biotechnology

Devices for drug delivery in the gastrointestinal tract: A review of systems physically interacting with the mucosa for enhanced delivery

(2021) James Byrne et al.   ADVANCED DRUG DELIVERY REVIEWS

Extraintestinal Manifestations of Inflammatory Bowel Disease: Current Concepts, Treatment, and Implications for Disease Management

(2021) Gerhard Rogler et al.   GASTROENTEROLOGY

5′-tiRNA-Cys-GCA regulates VSMC proliferation and phenotypic transition by targeting STAT4 in aortic dissection

(2021) Tingyu Zong et al.   Molecular Therapy-Nucleic Acids

Role of acetylation in doxorubicin-induced cardiotoxicity

(2021) Daisong Li et al.   Redox Biology

Nanomedicines for the Efficient Treatment of Intracellular Bacteria: The “ART” Principle

(2021) Hongzhao Qi et al.   Frontiers in Chemistry

Amyloid–Polyphenol Hybrid Nanofilaments Mitigate Colitis and Regulate Gut Microbial Dysbiosis

(2020) Bing Hu et al.   ACS Nano

Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss

(2020) Fanny Matheis et al.   CELL

The Stability Maintenance of Protein Drugs in Organic Coatings Based on Nanogels

(2020) Hongzhao Qi et al.   Pharmaceutics

M2 macrophages and phenotypic modulation of intestinal smooth muscle cells characterize Inflammatory stricture formation in the rat

(2020) Sandra R. Lourenssen et al.   AMERICAN JOURNAL OF PATHOLOGY

MMP-9 Processing of Intestinal Smooth Muscle-derived GDNF is Required for Neurotrophic Action on Enteric Neurons

(2020) Demetri Zoumboulakis et al.   NEUROSCIENCE

RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges

(2020) Ai-Ming Yu et al.   PHARMACOLOGICAL REVIEWS

Prognostic factors for advanced colorectal neoplasia in inflammatory bowel disease: systematic review and meta-analysis

(2020) Anouk M. Wijnands et al.   GASTROENTEROLOGY

Carboxymethyl chitosan microspheres loaded hyaluronic acid/gelatin hydrogels for controlled drug delivery and the treatment of inflammatory bowel disease

(2020) Shangwen Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus

(2020) Viorel Simion et al.   Nature Communications

Intestinal non-canonical NFκB signaling shapes the local and systemic immune response

(2019) Sadeesh K. Ramakrishnan et al.   Nature Communications

The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling

(2019) Feng-Xia Guo et al.   CELL DEATH AND DIFFERENTIATION

Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase 3 Expression

(2019) Wei-Ting Kuo et al.   GASTROENTEROLOGY

IL-33 promotes recovery from acute colitis by inducing miR-320 to stimulate epithelial restitution and repair

(2018) Loris R. Lopetuso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

American Gastroenterological Association Technical Review on the Management of Mild-to-Moderate Ulcerative Colitis

(2018) Siddharth Singh et al.   GASTROENTEROLOGY

A Molecular Targeted Immunotherapeutic Strategy for Ulcerative Colitis via Dual-Targeting Nanoparticles Delivering miR-146b to Intestinal Macrophages

(2018) Feihong Deng et al.   Journal of Crohns & Colitis

NOD2 Is Regulated By Mir-320 in Physiological Conditions but this Control Is Altered in Inflamed Tissues of Patients with Inflammatory Bowel Disease

(2016) Maria Pierdomenico et al.   INFLAMMATORY BOWEL DISEASES

An orally administrated nucleotide-delivery vehicle targeting colonic macrophages for the treatment of inflammatory bowel disease

(2015) Zhen Huang et al.   BIOMATERIALS

Nanoparticles With Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice

(2014) Bo Xiao et al.   GASTROENTEROLOGY

Mannosylated bioreducible nanoparticle-mediated macrophage-specific TNF-α RNA interference for IBD therapy

(2013) Bo Xiao et al.   BIOMATERIALS

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS