5′-tiRNA-Cys-GCA regulates VSMC proliferation and phenotypic transition by targeting STAT4 in aortic dissection

Targeting the epigenome in in-stent restenosis: from mechanisms to therapy

(2021) Xi Yang et al.   Molecular Therapy-Nucleic Acids

tsRNAs: Novel small molecules from cell function and regulatory mechanism to therapeutic targets

(2021) Tingyu Zong et al.   CELL PROLIFERATION

Exosomal LINC00174 derived from vascular endothelial cells attenuates myocardial I/R injury via p53-mediated autophagy and apoptosis

(2021) Qiang Su et al.   Molecular Therapy-Nucleic Acids

Nicotine: Regulatory roles and mechanisms in atherosclerosis progression

(2021) Xiuxiu Fu et al.   FOOD AND CHEMICAL TOXICOLOGY

The cellular function and molecular mechanism of formaldehyde in cardiovascular disease and heart development

(2021) Ying Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Expression profiles and potential roles of transfer RNA‐derived small RNAs in atherosclerosis

(2021) Xiangqin He et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Long noncoding RNA XXYLT1-AS2 regulates proliferation and adhesion by targeting the RNA binding protein FUS in HUVEC

(2020) Qi Wang et al.   ATHEROSCLEROSIS

The Stability Maintenance of Protein Drugs in Organic Coatings Based on Nanogels

(2020) Hongzhao Qi et al.   Pharmaceutics

Insights into the regulatory role of circRNA in angiogenesis and clinical implications

(2020) Yan Liu et al.   ATHEROSCLEROSIS

The kinase inhibitor BX795 suppresses the inflammatory response via multiple kinases

(2020) Tao Yu et al.   BIOCHEMICAL PHARMACOLOGY

Prevention of aortic dissection and aneurysm via an ALDH2-mediated switch in vascular smooth muscle cell phenotype

(2020) Kehui Yang et al.   EUROPEAN HEART JOURNAL

Avalanches and power law behavior in aortic dissection propagation

(2020) Xunjie Yu et al.   Science Advances

Functional roles and mechanisms of ginsenosides from Panax ginseng in atherosclerosis

(2020) Qianqian Xue et al.   Journal of Ginseng Research

Piwi-interacting RNAs (piRNAs) as potential biomarkers and therapeutic targets for cardiovascular diseases

(2020) Min Li et al.   ANGIOGENESIS

Non‐coding RNAs in aortic dissection: From biomarkers to therapeutic targets

(2020) Mengdie Cheng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

NLRP3 inflammasome in endothelial dysfunction

(2020) Baochen Bai et al.   Cell Death & Disease

MicroRNA-22 inhibits the apoptosis of vascular smooth muscle cell by targeting p38MAPKα in vascular remodeling of aortic dissection

(2020) Yu Xiao et al.   Molecular Therapy-Nucleic Acids

Suppression of miR-4463 promotes phenotypic switching in VSMCs treated with Ox-LDL

(2020) Xueqin Wang et al.   CELL AND TISSUE RESEARCH

Long Non-coding RNA PEBP1P2 Suppresses Proliferative VSMCs Phenotypic Switching and Proliferation in Atherosclerosis

(2020) Xingqiang He et al.   Molecular Therapy-Nucleic Acids

MiR-378a-5p Regulates Proliferation and Migration in Vascular Smooth Muscle Cell by Targeting CDK1

(2019) Shaoyan Liu et al.   Frontiers in Genetics

MicroRNA-134-5p Regulates Media Degeneration through Inhibiting Vascular Smooth Muscle Cell Phenotypic Switch and migration in Thoracic Aortic Dissection

(2019) Ying Wang et al.   Molecular Therapy-Nucleic Acids

tiRNAs as a novel biomarker for cell damage assessment in in vitro ischemia-reperfusion model in rat neuronal PC12 cells

(2019) Alaa Elkordy et al.   BRAIN RESEARCH

A tRNA fragment, 5′-tiRNAVal, suppresses the Wnt/β-catenin signaling pathway by targeting FZD3 in breast cancer

(2019) Dongping Mo et al.   CANCER LETTERS

Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro

(2019) Yichao Du et al.   Oxidative Medicine and Cellular Longevity

The potential and controversy of targeting STAT family members in cancer

(2019) Yannick Verhoeven et al.   SEMINARS IN CANCER BIOLOGY

Understanding the role of non-coding RNA (ncRNA) in stent restenosis

(2018) Shaoyan Liu et al.   ATHEROSCLEROSIS

Noncoding RNAs as therapeutic targets in atherosclerosis with diabetes mellitus

(2018) Ningning Tang et al.   Cardiovascular Therapeutics

The dysregulation of tRNAs and tRNA derivatives in cancer

(2018) Shi-qiong Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA

(2018) Siqi Li et al.   Genes

Transfer RNA-derived fragments and tRNA halves: biogenesis, biological functions and their roles in diseases

(2018) Yijing Shen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Large Differences in Small RNA Composition Between Human Biofluids

(2018) Paula M. Godoy et al.   Cell Reports

miRNAs as potential therapeutic targets and diagnostic biomarkers for cardiovascular disease with a particular focus on WO2010091204

(2017) Yanyan Yang et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A tRNA fragment, tRF5-Glu, regulates BCAR3 expression and proliferation in ovarian cancer cells

(2017) Kun Zhou et al.   Oncotarget

MicroRNA-125b attenuates epithelial-mesenchymal transitions and targets stem-like liver cancer cells through small mothers against decapentaplegic 2 and 4

(2015) Jun-Nian Zhou et al.   HEPATOLOGY

Brahma-related gene 1 inhibits proliferation and migration of human aortic smooth muscle cells by directly up-regulating Ras-related associated with diabetes in the pathophysiologic processes of aortic dissection

(2015) Wei-Lin Liao et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

STAT4 deficiency protects against neointima formation following arterial injury in mice

(2014) Lei Lv et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification and characterization of an ancient class of small RNAs enriched in serum associating with active infection

(2014) Yunfang Zhang et al.   Journal of Molecular Cell Biology

tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma

(2013) Roy L. Maute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide Identification and Quantitative Analysis of Cleaved tRNA Fragments Induced by Cellular Stress

(2012) Mridusmita Saikia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of smooth muscle cell phenotypes with extracellular matrix disorders in thoracic aortic dissection

(2012) Lixin Wang et al.   JOURNAL OF VASCULAR SURGERY

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis

(2012) Francesca Tuorto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Micromanaging Vascular Smooth Muscle Cell Differentiation and Phenotypic Modulation

(2011) Brandi N. Davis-Dusenbery et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections

(2010) Sakiko Inamoto et al.   CARDIOVASCULAR RESEARCH

Alterations in Aortic Cellular Constituents during Thoracic Aortic Aneurysm Development

(2009) Jeffrey A. Jones et al.   AMERICAN JOURNAL OF PATHOLOGY

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Highly efficient in vivo gene transfection by plasmid/PEI complexes coated by anionic PEG derivatives bearing carboxyl groups and RGD peptide

(2008) Mitsuko Sakae et al.   BIOMEDICINE & PHARMACOTHERAPY