The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling

Genistein Protects Against Ox-LDL-Induced Inflammation Through MicroRNA-155/SOCS1-Mediated Repression of NF-ĸB Signaling Pathway in HUVECs

(2017) Huaping Zhang et al.   INFLAMMATION

MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D

(2017) Kimberley D. Gutierrez et al.   JOURNAL OF IMMUNOLOGY

Suppression of autophagic flux contributes to cardiomyocyte death by activation of necroptotic pathways

(2017) Makoto Ogasawara et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Serum lincRNA-p21 as a potential biomarker of liver fibrosis in chronic hepatitis B patients

(2017) Fujun Yu et al.   JOURNAL OF VIRAL HEPATITIS

LincRNa-p21: function and mechanism in cancer

(2017) Shaoyun Chen et al.   MEDICAL ONCOLOGY

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy

(2017) Hong Yi et al.   Cell Death & Disease

Quercetin Inhibits LPS-Induced Inflammation and ox-LDL-Induced Lipid Deposition

(2017) Feng Xue et al.   Frontiers in Pharmacology

A novel regulatory network among LncRpa, CircRar1, MiR-671 and apoptotic genes promotes lead-induced neuronal cell apoptosis

(2016) Aruo Nan et al.   ARCHIVES OF TOXICOLOGY

Store-operated calcium entry-activated autophagy protects EPC proliferation via the CAMKK2-MTOR pathway in ox-LDL exposure

(2016) Jie Yang et al.   Autophagy

The Emerging Roles of Long Noncoding RNA ROR (lincRNA-ROR) and its Possible Mechanisms in Human Cancers

(2016) Yan Pan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Heat shock protein 70 inhibits cardiomyocyte necroptosis through repressing autophagy in myocardial ischemia/reperfusion injury

(2016) Xiaojuan Liu et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Neutrophil Necroptosis Is Triggered by Ligation of Adhesion Molecules following GM-CSF Priming

(2016) Xiaoliang Wang et al.   JOURNAL OF IMMUNOLOGY

VNN1 promotes atherosclerosis progression in apoE−/−mice fed a high-fat/high-cholesterol diet

(2016) Yan-Wei Hu et al.   JOURNAL OF LIPID RESEARCH

Autophagy protects against oxidized low density lipoprotein-mediated inflammation associated with preeclampsia

(2016) Yan Zhang et al.   PLACENTA

Systemic application of 3-methyladenine markedly inhibited atherosclerotic lesion in ApoE−/− mice by modulating autophagy, foam cell formation and immune-negative molecules

(2016) Shen Dai et al.   Cell Death & Disease

Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis

(2015) Mandy OJ Grootaert et al.   Autophagy

Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways

(2015) Shixuan Wang et al.   Autophagy

Modulation of inflammation by autophagy: Consequences for human disease

(2015) Romana T. Netea-Maier et al.   Autophagy

lncRNA-MIAT Regulates Microvascular Dysfunction by Functioning as a Competing Endogenous RNANovelty and Significance

(2015) Biao Yan et al.   CIRCULATION RESEARCH

Recent insights into cell death and autophagy

(2015) Brent E. Fitzwalter et al.   FEBS Journal

Autophagy in cardiovascular biology

(2015) Sergio Lavandero et al.   JOURNAL OF CLINICAL INVESTIGATION

Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway

(2015) Xiaodi Fan et al.   Journal of Translational Medicine

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

(2015) Kate E. Lawlor et al.   Nature Communications

RIP kinases: key decision makers in cell death and innate immunity

(2014) F Humphries et al.   CELL DEATH AND DIFFERENTIATION

Noncoding RNAs and Atherosclerosis

(2014) Binod Aryal et al.   Current Atherosclerosis Reports

Delphinidin-3-glucoside protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury by autophagy upregulation via the AMPK/SIRT1 signaling pathway

(2014) Xin Jin et al.   MOLECULAR NUTRITION & FOOD RESEARCH

TRPV1 activation impedes foam cell formation by inducing autophagy in oxLDL-treated vascular smooth muscle cells

(2014) B-H Li et al.   Cell Death & Disease

Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathway

(2013) Ming-liang Chen et al.   Autophagy

Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes

(2013) F Basit et al.   CELL DEATH AND DIFFERENTIATION

The lysosome: from waste bag to potential therapeutic target

(2013) Hanna Appelqvist et al.   Journal of Molecular Cell Biology

IGF-1 alleviates ox-LDL-induced inflammation via reducing HMGB1 release in HAECs

(2012) X. Yu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedforward Loops Is Required for Development of Pancreatic Ductal Adenocarcinoma

(2012) Jianhua Ling et al.   CANCER CELL

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

(2012) Xianghai Liao et al.   Cell Metabolism

Mechanisms and regulation of autophagosome formation

(2012) Claudine Kraft et al.   CURRENT OPINION IN CELL BIOLOGY

Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis

(2012) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromatin Isolation by RNA Purification (ChIRP)

(2012) Ci Chu et al.   Jove-Journal of Visualized Experiments

Autophagy in Atherosclerosis

(2011) Dorien M. Schrijvers et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vertical Targeting of the Phosphatidylinositol-3 Kinase Pathway as a Strategy for Treating Melanoma

(2010) S. A. Aziz et al.   CLINICAL CANCER RESEARCH

Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

(2009) Sudan He et al.   CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE