Nanomedicines for the Efficient Treatment of Intracellular Bacteria: The “ART” Principle

tsRNAs: Novel small molecules from cell function and regulatory mechanism to therapeutic targets

(2021) Tingyu Zong et al.   CELL PROLIFERATION

Enhanced Eradication of Bacterial/Fungi Biofilms by Glucose Oxidase-Modified Magnetic Nanoparticles as a Potential Treatment for Persistent Endodontic Infections

(2021) Yanjing Ji et al.   ACS Applied Materials & Interfaces

Recent advances in tumor microenvironment-targeted nanomedicine delivery approaches to overcome limitations of immune checkpoint blockade-based immunotherapy

(2021) Jaehyun Kim et al.   JOURNAL OF CONTROLLED RELEASE

Bio‐Multifunctional Hydrogel Patches for Repairing Full‐Thickness Abdominal Wall Defect

(2021) Xiangyi Yin et al.   ADVANCED FUNCTIONAL MATERIALS

Hierarchically hybrid biocoatings on Ti implants for enhanced antibacterial activity and osteogenesis

(2021) Zheng Wang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Marine polysaccharide-based composite hydrogels containing fucoidan: Preparation, physicochemical characterization, and biocompatible evaluation

(2021) Yuanping Hao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Fucoidan as a marine-origin prebiotic modulates the growth and antibacterial ability of Lactobacillus rhamnosus

(2021) Yanli Zhu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Extracellular Vesicles as Natural Delivery Carriers Regulate Oxidative Stress Under Pathological Conditions

(2021) Hongzhao Qi et al.   Frontiers in Bioengineering and Biotechnology

Preparation of triamcinolone acetonide-loaded chitosan/fucoidan hydrogel and its potential application as an oral mucosa patch

(2021) Weiping Zheng et al.   CARBOHYDRATE POLYMERS

The Stability Maintenance of Protein Drugs in Organic Coatings Based on Nanogels

(2020) Hongzhao Qi et al.   Pharmaceutics

Reconstructed Apoptotic Bodies as Targeted “Nano Decoys” to Treat Intracellular Bacterial Infections within Macrophages and Cancer Cells

(2020) Rajendran J. C. Bose et al.   ACS Nano

Reactive Oxygen Species-Related Nanoparticle Toxicity in the Biomedical Field

(2020) Zhongjie Yu et al.   Nanoscale Research Letters

Polymersomes Eradicating Intracellular Bacteria

(2020) Federico Fenaroli et al.   ACS Nano

Exploiting the dynamics of the EPR effect and strategies to improve the therapeutic effects of nanomedicines by using EPR effect enhancers

(2020) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Intracellular Pathogen Detection Based on Dual-Recognition Units Constructed Fluorescence Resonance Energy Transfer Nanoprobe

(2020) Fei Fu et al.   ANALYTICAL CHEMISTRY

Coating of a Novel Antimicrobial Nanoparticle with a Macrophage Membrane for the Selective Entry into Infected Macrophages and Killing of Intracellular Staphylococci

(2020) Yuanfeng Li et al.   ADVANCED FUNCTIONAL MATERIALS

Biodistribution and intracellular localization of hyaluronan and its nanogels. A strategy to target intracellular S. aureus in persistent skin infections

(2020) E. Montanari et al.   JOURNAL OF CONTROLLED RELEASE

A biodegradable antibacterial alginate/carboxymethyl chitosan/Kangfuxin sponges for promoting blood coagulation and full-thickness wound healing

(2020) Yun He et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Compartmentalized Encapsulation of Two Antibiotics in Porous Nanoparticles: an Efficient Strategy to Treat Intracellular Infections

(2019) Xue Li et al.   PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION

Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy

(2019) Lei Han et al.   ADVANCED MATERIALS

PLGA nanocapsules improve the delivery of clarithromycin to kill intracellular Staphylococcus aureus and Mycobacterium abscessus

(2019) Frantiescoli Anversa Dimer et al.   Nanomedicine-Nanotechnology Biology and Medicine

Bacteria-Targeting Nanoparticles with Microenvironment-Responsive Antibiotic Release To Eliminate Intracellular Staphylococcus aureus and Associated Infection

(2018) Shengbing Yang et al.   ACS Applied Materials & Interfaces

Macrophage-Instructed Intracellular Staphylococcus aureus Killing by Targeting Photodynamic Dimers

(2018) Qian Cai et al.   ACS Applied Materials & Interfaces

Exosomes separated based on the “STOP” criteria for tumor-targeted drug delivery

(2018) Hongzhao Qi et al.   Journal of Materials Chemistry B

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models

(2018) Federico Fenaroli et al.   ACS Nano

Chemotaxis-Instructed Intracellular Staphylococcus aureus Infection Detection by a Targeting and Self-Assembly Signal-Enhanced Photoacoustic Probe

(2018) Qian Cai et al.   NANO LETTERS

Magnetic Nanoconjugated Teicoplanin: A Novel Tool for Bacterial Infection Site Targeting

(2018) Ilaria Armenia et al.   Frontiers in Microbiology

Kill the Real with the Fake: Eliminate Intracellular Staphylococcus aureus Using Nanoparticle Coated with Its Extracellular Vesicle Membrane as Active-Targeting Drug Carrier

(2018) Feng Gao et al.   ACS Infectious Diseases

Hyaluronic acid conjugation facilitates clearance of intracellular bacterial infections by streptomycin with neglectable nephrotoxicity

(2017) Yuanhao Qiu et al.   GLYCOBIOLOGY

Multivalent gold nanoparticle–peptide conjugates for targeting intracellular bacterial infections

(2017) Rimi Chowdhury et al.   Nanoscale

Development of arginine based nanocarriers for targeting and treatment of intracellular Salmonella

(2017) Rajeev J. Mudakavi et al.   RSC Advances

Dual functionality nanobioconjugates targeting intracellular bacteria in cancer cells with enhanced antimicrobial activity

(2017) Rohini Singh et al.   Scientific Reports

Blood Exosomes Endowed with Magnetic and Targeting Properties for Cancer Therapy

(2016) Hongzhao Qi et al.   ACS Nano

Targeting the hard to reach: challenges and novel strategies in the treatment of intracellular bacterial infections

(2016) Nor Fadhilah Kamaruzzaman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Impact of micro-environmental changes on respiratory tract infections with intracellular bacteria

(2016) Kensuke Shima et al.   FEBS LETTERS

Novel antibody–antibiotic conjugate eliminates intracellular S. aureus

(2015) Sophie M. Lehar et al.   NATURE

Nanoparticles as Drug Delivery System against Tuberculosis in Zebrafish Embryos: Direct Visualization and Treatment

(2014) Federico Fenaroli et al.   ACS Nano

Nanocarriers for antibiotics: A promising solution to treat intracellular bacterial infections

(2014) Nadia Abed et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Magnetic targeting of surface-modified superparamagnetic iron oxide nanoparticles yields antibacterial efficacy against biofilms of gentamicin-resistant staphylococci

(2012) Guruprakash Subbiahdoss et al.   Acta Biomaterialia

Extrapulmonary Locations of Mycobacterium tuberculosis DNA During Latent Infection

(2012) Jorge Barrios-Payán et al.   JOURNAL OF INFECTIOUS DISEASES

The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles

(2011) Kai Xiao et al.   BIOMATERIALS

Intracellular pathogens: living in an extreme environment

(2011) Stefan H. E. Kaufmann   IMMUNOLOGICAL REVIEWS

Novel bioactive hydrophobic gentamicin carriers for the treatment of intracellular bacterial infections

(2010) Edurne Imbuluzqueta et al.   Acta Biomaterialia

Antibacterial efficacy of core-shell nanostructures encapsulating gentamicin against an in vivo intracellular  Salmonella model

(2010) Ashish Ranjan   International Journal of Nanomedicine