- Home
- Publications
- Publication Search
- Publication Details
Title
The fibrosis-cell death axis in heart failure
Authors
Keywords
Fibrosis, Heart failure, Cardiomyocyte, Cell death, Fibroblast, Myofibroblast, TGFβ, Hypertrophy
Journal
HEART FAILURE REVIEWS
Volume 21, Issue 2, Pages 199-211
Publisher
Springer Nature
Online
2016-02-16
DOI
10.1007/s10741-016-9536-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Pirfenidone exhibits cardioprotective effects by regulating myocardial fibrosis and vascular permeability in pressure-overloaded hearts
- (2015) Kiyoshi Yamagami et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Modulation of cardiac fibrosis by Krüppel-like factor 6 through transcriptional control of thrombospondin 4 in cardiomyocytes
- (2015) Daigo Sawaki et al. CARDIOVASCULAR RESEARCH
- Functional crosstalk between cardiac fibroblasts and adult cardiomyocytes by soluble mediators
- (2015) James E. Cartledge et al. CARDIOVASCULAR RESEARCH
- Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart
- (2015) Kate M. Herum et al. CARDIOVASCULAR RESEARCH
- Matrix cross-linking lysyl oxidases are induced in response to myocardial infarction and promote cardiac dysfunction
- (2015) José González-Santamaría et al. CARDIOVASCULAR RESEARCH
- Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis
- (2015) Rafael Kramann et al. Cell Stem Cell
- Omecamtiv mecarbil: a new cardiac myosin activator for the treatment of heart failure
- (2015) Licette CY Liu et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Circulating Biomarkers of Myocardial Fibrosis
- (2015) Begoña López et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Fibrosis — A Common Pathway to Organ Injury and Failure
- (2015) Don C. Rockey et al. NEW ENGLAND JOURNAL OF MEDICINE
- Developmental Heterogeneity of Cardiac Fibroblasts Does Not Predict Pathological Proliferation and Activation
- (2014) Shah R. Ali et al. CIRCULATION RESEARCH
- Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression
- (2014) Jordi Heijman et al. CIRCULATION RESEARCH
- Galectin-3 in patients with heart failure with preserved ejection fraction: results from the Aldo-DHF trial
- (2014) Frank Edelmann et al. EUROPEAN JOURNAL OF HEART FAILURE
- Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis
- (2014) Thomas Moore-Morris et al. JOURNAL OF CLINICAL INVESTIGATION
- Attenuated development of cardiac fibrosis in left ventricular pressure overload by SM16, an orally active inhibitor of ALK5
- (2014) Kristin V.T. Engebretsen et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- miR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 signaling
- (2014) Yang Zhang et al. MOLECULAR THERAPY
- Noncoding RNAs and myocardial fibrosis
- (2014) Thomas Thum Nature Reviews Cardiology
- Extracellular matrix assembly: a multiscale deconstruction
- (2014) Janna K. Mouw et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Remodelling the extracellular matrix in development and disease
- (2014) Caroline Bonnans et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TGF-β Activation and Function in Immunity
- (2013) Mark A. Travis et al. Annual Review of Immunology
- Biomarkers and diagnostics in heart failure
- (2013) Hanna K. Gaggin et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Osteopontin-mediated myocardial fibrosis in heart failure: a role for lysyl oxidase?
- (2013) Begoña López et al. CARDIOVASCULAR RESEARCH
- Reversible and irreversible differentiation of cardiac fibroblasts
- (2013) Ronald B. Driesen et al. CARDIOVASCULAR RESEARCH
- The pathogenesis of cardiac fibrosis
- (2013) Ping Kong et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Pathological Ventricular Remodeling
- (2013) Jana S. Burchfield et al. CIRCULATION
- Epidemiology of Heart Failure
- (2013) Véronique L. Roger CIRCULATION RESEARCH
- Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND
- (2013) F. P. Brouwers et al. EUROPEAN HEART JOURNAL
- Effective myofibroblast dedifferentiation by concomitant inhibition of TGF-β signaling and perturbation of MAPK signaling
- (2013) Jan Kosla et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Targeting Sarcoplasmic Reticulum Calcium ATPase by Gene Therapy
- (2013) Judith K. Gwathmey et al. HUMAN GENE THERAPY
- 2013 ACCF/AHA Guideline for the Management of Heart Failure
- (2013) Clyde W. Yancy et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Heart repair by cardiac reprogramming
- (2013) Young-Jae Nam et al. NATURE MEDICINE
- Cathepsin B Is Up-Regulated and Mediates Extracellular Matrix Degradation in Trabecular Meshwork Cells Following Phagocytic Challenge
- (2013) Kristine Porter et al. PLoS One
- Reprogramming of human fibroblasts toward a cardiac fate
- (2013) Y.-J. Nam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of interleukin-1 on cardiac fibroblast function: Relevance to post-myocardial infarction remodelling
- (2013) Neil A. Turner VASCULAR PHARMACOLOGY
- Recent Developments in Myofibroblast Biology
- (2012) Boris Hinz et al. AMERICAN JOURNAL OF PATHOLOGY
- Cellular Mechanisms of Tissue Fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis
- (2012) Michael Zeisberg et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload
- (2012) Misun Park et al. BASIC RESEARCH IN CARDIOLOGY
- Genetic and Pharmacological Inhibition of Galectin-3 Prevents Cardiac Remodeling by Interfering With Myocardial Fibrogenesis
- (2012) Lili Yu et al. Circulation-Heart Failure
- Fibrosis and heart failure
- (2012) Ana Maria Segura et al. HEART FAILURE REVIEWS
- Heart repair by reprogramming non-myocytes with cardiac transcription factors
- (2012) Kunhua Song et al. NATURE
- Identification of hypertrophy- and heart failure-associated genes by combining in vitro and in vivo models
- (2012) Bo Lu et al. PHYSIOLOGICAL GENOMICS
- Macrophage-Stimulated Cardiac Fibroblast Production of IL-6 Is Essential for TGF β/Smad Activation and Cardiac Fibrosis Induced by Angiotensin II
- (2012) Feifei Ma et al. PLoS One
- Role of Endothelial-Mesenchymal Transition (EndoMT) in the Pathogenesis of Fibrotic Disorders
- (2011) Sonsoles Piera-Velazquez et al. AMERICAN JOURNAL OF PATHOLOGY
- Regulation of endothelial cell plasticity by TGF-β
- (2011) Laurens A. van Meeteren et al. CELL AND TISSUE RESEARCH
- Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)
- (2011) Mariell Jessup et al. CIRCULATION
- Abolishing Myofibroblast Arrhythmogeneicity by Pharmacological Ablation of α-Smooth Muscle Actin Containing Stress Fibers
- (2011) Christian Rosker et al. CIRCULATION RESEARCH
- Programmed Necrosis, Not Apoptosis, in the Heart
- (2011) Gloria Kung et al. CIRCULATION RESEARCH
- Transforming Growth Factor-β
- (2011) Navin K. Kapur Circulation-Heart Failure
- New Insights into the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis
- (2011) Qiang Ding et al. DRUGS
- Cardiac myosin activation part 1: From concept to clinic
- (2011) Fady I. Malik et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Microvascular Dysfunction: A Potential Mechanism in the Pathogenesis of Obesity-associated Insulin Resistance and Hypertension
- (2011) MICHIEL P. DE BOER et al. MICROCIRCULATION
- The Athlete's Heart vs. the Failing Heart: Can Signaling Explain the Two Distinct Outcomes?
- (2011) Kate L. Weeks et al. PHYSIOLOGY
- Induction of Heart Valve Lesions by Small-Molecule ALK5 Inhibitors
- (2011) Mark J. Anderton et al. TOXICOLOGIC PATHOLOGY
- Cardiomyocyte death: mechanisms and translational implications
- (2011) M Chiong et al. Cell Death & Disease
- Predictive value of plasma galectin-3 levels in heart failure with reduced and preserved ejection fraction
- (2010) Rudolf A. de Boer et al. ANNALS OF MEDICINE
- Mechanisms of atrial structural changes caused by stretch occurring before and during early atrial fibrillation
- (2010) A. M. De Jong et al. CARDIOVASCULAR RESEARCH
- Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart
- (2010) E. E. Creemers et al. CARDIOVASCULAR RESEARCH
- Molecular Pathways Underlying Cardiac Remodeling During Pathophysiological Stimulation
- (2010) Izhak Kehat et al. CIRCULATION
- Intramyocardial Fibroblast Myocyte Communication
- (2010) Rahul Kakkar et al. CIRCULATION RESEARCH
- High-Sensitivity ST2 for Prediction of Adverse Outcomes in Chronic Heart Failure
- (2010) Bonnie Ky et al. Circulation-Heart Failure
- Interleukin 6 Mediates Myocardial Fibrosis, Concentric Hypertrophy, and Diastolic Dysfunction in Rats
- (2010) Giselle C. Meléndez et al. HYPERTENSION
- Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice
- (2010) David M. Patrick et al. JOURNAL OF CLINICAL INVESTIGATION
- Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation
- (2010) Volker Rudolph et al. NATURE MEDICINE
- Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies
- (2010) Bianca C. Bernardo et al. PHARMACOLOGY & THERAPEUTICS
- Endothelin-1 and Transforming Growth Factor-β1 Independently Induce Fibroblast Resistance to Apoptosis via AKT Activation
- (2009) Priya Kulasekaran et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The role of IL-1 in the pathogenesis of heart disease
- (2009) Marcin Bujak et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Cardiac Fibroblast
- (2009) Colby A. Souders et al. CIRCULATION RESEARCH
- ASK1 Regulates Cardiomyocyte Death but Not Hypertrophy in Transgenic Mice
- (2009) Qinghang Liu et al. CIRCULATION RESEARCH
- A novel approach to improve cardiac performance: cardiac myosin activators
- (2009) John R. Teerlink HEART FAILURE REVIEWS
- Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload
- (2009) Norifumi Takeda et al. JOURNAL OF CLINICAL INVESTIGATION
- Antagonism of endothelin-1 inhibits hypoxia-induced apoptosis in cardiomyocytesThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin.
- (2008) Anjing Ren et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Nix-Mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation
- (2008) Abhinav Diwan et al. CIRCULATION
- Depressed Coronary Flow Reserve Is Associated With Decreased Myocardial Capillary Density in Patients With Heart Failure Due to Idiopathic Dilated Cardiomyopathy
- (2008) Eleftheria P. Tsagalou et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Atrial Fibrosis: Mechanisms and Clinical Relevance in Atrial Fibrillation
- (2008) Brett Burstein et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
- (2008) Thomas Thum et al. NATURE
- Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
- (2008) E. van Rooij et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now