New Insights into the Pathogenesis and Treatment of Idiopathic Pulmonary Fibrosis

Occupational Risks for Idiopathic Pulmonary Fibrosis Mortality in the United States

(2014) Germania A. Pinheiro et al.   INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH

Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis

(2010) Kusum V. Pandit et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Modulation of K-Ras-Dependent Lung Tumorigenesis by MicroRNA-21

(2010) Mark E. Hatley et al.   CANCER CELL

Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

(2010) Y. Cheng et al.   CARDIOVASCULAR RESEARCH

Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts

(2010) Guo-qiang Cai et al.   EXPERIMENTAL CELL RESEARCH

Thy-1-Integrin αvβ5Interactions Inhibit Lung Fibroblast Contraction-induced Latent Transforming Growth Factor-β1 Activation and Myofibroblast Differentiation

(2010) Yong Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

(2010) Gang Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway

(2010) Eugene D Ponomarev et al.   NATURE MEDICINE

A Controlled Trial of Sildenafil in Advanced Idiopathic Pulmonary Fibrosis

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Prevalence and impact of coronary artery disease in idiopathic pulmonary fibrosis

(2010) Steven D. Nathan et al.   RESPIRATORY MEDICINE

Short Telomeres are Sufficient to Cause the Degenerative Defects Associated with Aging

(2009) Mary Armanios et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Serum CC-Chemokine Ligand 18 Concentration Predicts Outcome in Idiopathic Pulmonary Fibrosis

(2009) Antje Prasse et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Contribution of Epithelial-derived Fibroblasts to Bleomycin-induced Lung Fibrosis

(2009) Harikrishna Tanjore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Imatinib Treatment for Idiopathic Pulmonary Fibrosis

(2009) Craig E. Daniels et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endothelial–Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis

(2009) Naozumi Hashimoto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Accelerated lung aging: a novel pathogenic mechanism of chronic obstructive pulmonary disease (COPD)

(2009) William MacNee   BIOCHEMICAL SOCIETY TRANSACTIONS

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines

(2009) Hongli Shan et al.   CARDIOVASCULAR RESEARCH

MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue

(2009) Sashwati Roy et al.   CARDIOVASCULAR RESEARCH

Obstructive Sleep Apnea Is Common in Idiopathic Pulmonary Fibrosis

(2009) Lisa H. Lancaster et al.   CHEST

Serum Surfactant Protein-A Is a Strong Predictor of Early Mortality in Idiopathic Pulmonary Fibrosis

(2009) Brent W. Kinder et al.   CHEST

MicroRNA-145, a Novel Smooth Muscle Cell Phenotypic Marker and Modulator, Controls Vascular Neointimal Lesion Formation

(2009) Yunhui Cheng et al.   CIRCULATION RESEARCH

Pirfenidone in idiopathic pulmonary fibrosis

(2009) H. Taniguchi et al.   EUROPEAN RESPIRATORY JOURNAL

MICA polymorphisms and decreased expression of the MICA receptor NKG2D contribute to idiopathic pulmonary fibrosis susceptibility

(2009) Arnoldo Aquino-Galvez et al.   HUMAN GENETICS

The mechanical integrin cycle

(2009) E. Puklin-Faucher et al.   JOURNAL OF CELL SCIENCE

Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial

(2009) Talmadge E King et al.   LANCET

TGF-β activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

(2009) Mitsuo Kato et al.   NATURE CELL BIOLOGY

MicroRNA MiR-17 retards tissue growth and represses fibronectin expression

(2009) Sze Wan Shan et al.   NATURE CELL BIOLOGY

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

In Vitro and In Vivo Evidence that Thrombospondin-1 (TSP-1) Contributes to Stirring- and Shear-Dependent Activation of Platelet-Derived TGF-β1

(2009) Jasimuddin Ahamed et al.   PLoS One

Identification of Keratinocyte Growth Factor as a Target of microRNA-155 in Lung Fibroblasts: Implication in Epithelial-Mesenchymal Interactions

(2009) Nicolas Pottier et al.   PLoS One

Risk factors for idiopathic pulmonary fibrosis in a Mexican population. A case-control study

(2009) Ma. Cecilia García-Sancho Figueroa et al.   RESPIRATORY MEDICINE

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

A Role for the Receptor for Advanced Glycation End Products in Idiopathic Pulmonary Fibrosis

(2008) Judson M. Englert et al.   AMERICAN JOURNAL OF PATHOLOGY

Latent Transforming Growth Factor-β-Binding Protein-4 Regulates Transforming Growth Factor-β1 Bioavailability for Activation by Fibrogenic Lung Fibroblasts in Response to Bleomycin

(2008) Yong Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection

(2008) William E. Lawson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Exacerbation of Established Pulmonary Fibrosis in a Murine Model by Gammaherpesvirus

(2008) Tracy R. McMillan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Idiopathic Pulmonary Fibrosis

(2008) Victor J. Thannickal et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis

(2008) Martina Korfei et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Association between Idiopathic Pulmonary Fibrosis and Vascular Disease

(2008) Richard B. Hubbard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Treatment of Idiopathic Pulmonary Fibrosis with Etanercept

(2008) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Telomere Shortening in Familial and Sporadic Pulmonary Fibrosis

(2008) Jennifer T. Cronkhite et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Gastroesophageal Reflux and Pulmonary Fibrosis in Scleroderma

(2008) Edoardo Savarino et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Loss of RAGE in Pulmonary Fibrosis

(2008) Markus A. Queisser et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Src kinases in systemic sclerosis: Central roles in fibroblast activation and in skin fibrosis

(2008) Catherine Skhirtladze et al.   ARTHRITIS AND RHEUMATISM

In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor- 1

(2008) J. Ahamed et al.   BLOOD

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin

(2008) Marjan Boerma et al.   BLOOD COAGULATION & FIBRINOLYSIS

Therapeutic potential of RhoA/Rho kinase inhibitors in pulmonary hypertension

(2008) M Oka et al.   BRITISH JOURNAL OF PHARMACOLOGY

miR-133 and miR-30 Regulate Connective Tissue Growth Factor

(2008) Rudy F. Duisters et al.   CIRCULATION RESEARCH

Focal Adhesion Kinase: Targeting Adhesion Signaling Pathways for Therapeutic Intervention

(2008) J. T. Parsons et al.   CLINICAL CANCER RESEARCH

Protein Kinase Inhibitors in the Treatment of Pulmonary Fibrosis

(2008) Sylvie Garneau-Tsodikova et al.   CURRENT MEDICINAL CHEMISTRY

Rho kinase inhibitors: A novel therapeutical intervention in asthma?

(2008) Dedmer Schaafsma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

MMP-1 polymorphisms and the risk of idiopathic pulmonary fibrosis

(2008) Marco Checa et al.   HUMAN GENETICS

Prevalência de refluxo gastroesofágico em pacientes com doença pulmonar avançada candidatos a transplante pulmonar

(2008) Gustavo Almeida Fortunato et al.   Jornal Brasileiro de Pneumologia

Focal Adhesion Kinase (FAK)-related Non-kinase Inhibits Myofibroblast Differentiation through Differential MAPK Activation in a FAK-dependent Manner

(2008) Qiang Ding et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Short telomeres are a risk factor for idiopathic pulmonary fibrosis

(2008) J. K. Alder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

(2008) E. van Rooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of diabetes mellitus and gastro-oesophageal reflux in the aetiology of idiopathic pulmonary fibrosis

(2008) Jonathan Gribbin et al.   RESPIRATORY MEDICINE

MMP1 and MMP7 as Potential Peripheral Blood Biomarkers in Idiopathic Pulmonary Fibrosis

(2008) Ivan O Rosas et al.   PLOS MEDICINE

Idiopathic Pulmonary Fibrosis

(2007) Katerina M. Antoniou et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

BUILD-1: A Randomized Placebo-controlled Trial of Bosentan in Idiopathic Pulmonary Fibrosis

(2007) Talmadge E. King et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Serum levels of oxidative stress as a marker of disease severity in idiopathic pulmonary fibrosis

(2006) Zoe D. Daniil et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS