SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells

Severely ill COVID-19 patients display impaired exhaustion features in SARS-CoV-2-reactive CD8+ T cells

(2021) Anthony Kusnadi et al.   Science Immunology

Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany

(2020) Camilla Rothe et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Coronavirus Disease 2019: Coronaviruses and Blood Safety

(2020) Le Chang et al.   TRANSFUSION MEDICINE REVIEWS

The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections

(2020) Eri Katsuyama et al.   Cell Reports

Pathological findings of COVID-19 associated with acute respiratory distress syndrome

(2020) Zhe Xu et al.   Lancet Respiratory Medicine

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

(2020) Pierre Bost et al.   CELL

COVID-19 infection: the perspectives on immune responses

(2020) Yufang Shi et al.   CELL DEATH AND DIFFERENTIATION

The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?

(2020) Julia L. McKechnie et al.   Cell Host & Microbe

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

A Dynamic Immune Response Shapes COVID-19 Progression

(2020) Eugenia Ziying Ong et al.   Cell Host & Microbe

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

A Review of Coronavirus Disease-2019 (COVID-19)

(2020) Tanu Singhal   INDIAN JOURNAL OF PEDIATRICS

Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern: The Fragile Balance between Infections and Autoimmunity

(2020) Andrea Picchianti Diamanti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Perforin and resistance to SARS coronavirus 2

(2020) Louise Cunningham et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesis

(2020) Sean Quan Du et al.   JOURNAL OF MEDICAL VIROLOGY

Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19

(2020) Irani Thevarajan et al.   NATURE MEDICINE

Metabolic Reprogramming in CD8+ T Cells During Acute Viral Infections

(2020) Shubhranshu S. Gupta et al.   Frontiers in Immunology

Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)

(2020) Bo Diao et al.   Frontiers in Immunology

Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients

(2020) Jing Liu et al.   EBioMedicine

Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing

(2020) Wen Wen et al.   Cell Discovery

Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19

(2020) Aymeric Silvin et al.   CELL

Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells

(2020) Yunlong Cao et al.   CELL

Lymphocyte Subset Counts in COVID ‐19 Patients: A Meta‐Analysis

(2020) Wei Huang et al.   CYTOMETRY PART A

Perforin gene variant A91V in young patients with severe COVID-19.

(2020) Oscar Cabrera-Marante et al.   HAEMATOLOGICA

Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses

(2020) Runhong Zhou et al.   IMMUNITY

Mild versus severe COVID-19: Laboratory markers

(2020) Thirumalaisamy P. Velavan et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent

(2020) Alessio Mazzoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Single-cell landscape of immunological responses in patients with COVID-19

(2020) Ji-Yuan Zhang et al.   NATURE IMMUNOLOGY

Immunological and inflammatory profiles in mild and severe cases of COVID-19

(2020) Jin-Wen Song et al.   Nature Communications

Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

(2020) Sara De Biasi et al.   Nature Communications

Immune and Metabolic Signatures of COVID-19 Revealed by Transcriptomics Data Reuse

(2020) Luiz G. Gardinassi et al.   Frontiers in Immunology

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

(2020) Daniela Weiskopf et al.   Science Immunology

Clinical and Immune Features of Hospitalized Pediatric Patients With Coronavirus Disease 2019 (COVID-19) in Wuhan, China

(2020) Huan Wu et al.   JAMA Network Open

Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

(2020) Ana Campos Codo et al.   Cell Metabolism

COVID-19 pneumonia: CD8+ T and NK cells are decreased in number but compensatory increased in cytotoxic potential

(2020) Yujie Jiang et al.   CLINICAL IMMUNOLOGY

Sex differences in immune responses that underlie COVID-19 disease outcomes

(2020) Takehiro Takahashi et al.   NATURE

An inflammatory cytokine signature predicts COVID-19 severity and survival

(2020) Diane Marie Del Valle et al.   NATURE MEDICINE

High Fructose Induced Metabolic Changes Enhance Inflammation in Human Dendritic Cells

(2019) Natasha Jaiswal et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Virus Control of Cell Metabolism for Replication and Evasion of Host Immune Responses

(2019) María Maximina B. Moreno-Altamirano et al.   Frontiers in Cellular and Infection Microbiology

Viral hijacking of cellular metabolism

(2019) Shivani K. Thaker et al.   BMC BIOLOGY

T cell metabolism in chronic viral infection

(2019) L. J. Pallett et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Peripheral Blood Mononuclear Cell Metabolism Acutely Adapted to Postprandial Transition and Mainly Reflected Metabolic Adipose Tissue Adaptations to a High-Fat Diet in Minipigs

(2018) Yuchun Zeng et al.   Nutrients

Characterization of Human Monocyte Subsets by Whole Blood Flow Cytometry Analysis

(2018) Rekha Marimuthu et al.   Jove-Journal of Visualized Experiments

Sugar or Fat?—Metabolic Requirements for Immunity to Viral Infections

(2017) Hesham M. Shehata et al.   Frontiers in Immunology

An optimized multiplex flow cytometry protocol for the analysis of intracellular signaling in peripheral blood mononuclear cells

(2016) Richard Davies et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

(2016) Mahima Swamy et al.   NATURE IMMUNOLOGY

Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1

(2016) Dominika J. Maskus et al.   Scientific Reports

Virus-Specific Memory CD8 T Cells Provide Substantial Protection from Lethal Severe Acute Respiratory Syndrome Coronavirus Infection

(2014) R. Channappanavar et al.   JOURNAL OF VIROLOGY

Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species

(2014) Max W.S. Oliveira et al.   Pharmacological Reports

Immunity to viruses

(2013) Thomas J. Braciale et al.   IMMUNOLOGICAL REVIEWS

The three human monocyte subsets: implications for health and disease

(2012) Kok Loon Wong et al.   IMMUNOLOGIC RESEARCH

Reducing Time and Increasing Sensitivity in Sample Preparation for Adherent Mammalian Cell Metabolomics

(2011) Matthew A. Lorenz et al.   ANALYTICAL CHEMISTRY

The PD-1 pathway in tolerance and autoimmunity

(2010) Loise M. Francisco et al.   IMMUNOLOGICAL REVIEWS

Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells

(2009) C. Ferreira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA