BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology
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Title
BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology
Authors
Keywords
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Journal
iScience
Volume 24, Issue 9, Pages 102942
Publisher
Elsevier BV
Online
2021-08-04
DOI
10.1016/j.isci.2021.102942
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Note: Only part of the references are listed.- Systemic inflammation impairs microglial Aβ clearance through NLRP 3 inflammasome
- (2019) Dario Tejera et al. EMBO JOURNAL
- Ageing as a risk factor for neurodegenerative disease
- (2019) Yujun Hou et al. Nature Reviews Neurology
- Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
- (2019) Justin M. Long et al. CELL
- NLRP3 inflammasome activation drives tau pathology
- (2019) Christina Ising et al. NATURE
- The BH3-only protein BAD mediates TNFα cytotoxicity despite concurrent activation of IKK and NF-κB in septic shock
- (2018) Jie Yan et al. CELL RESEARCH
- TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function
- (2018) Yingjun Zhao et al. NEURON
- Direct pharmacological Akt activation rescues Alzheimer's disease like memory impairments and aberrant synaptic plasticity
- (2018) Jee Hyun Yi et al. NEUROPHARMACOLOGY
- New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
- (2018) Zhenyu Zhong et al. NATURE
- Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease
- (2017) Carmen Venegas et al. NATURE
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Necroptosis activation in Alzheimer's disease
- (2017) Antonella Caccamo et al. NATURE NEUROSCIENCE
- A Brief History of Long-Term Potentiation
- (2017) Roger A. Nicoll NEURON
- Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice
- (2017) Qiaoqiao Shi et al. Science Translational Medicine
- Increased apoptosis in the platelets of patients with Alzheimer’s disease and amnestic mild cognitive impairment
- (2016) Shengjie Zhao et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
- (2016) Peng Yuan et al. NEURON
- Therapeutic strategies for Alzheimer's disease in clinical trials
- (2016) Justyna Godyń et al. Pharmacological Reports
- Prevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL
- (2016) Yan Chen Shang et al. Aging-US
- Neuroinflammation in Alzheimer's disease
- (2015) Michael T Heneka et al. LANCET NEUROLOGY
- Innate immunity in Alzheimer's disease
- (2015) Michael T Heneka et al. NATURE IMMUNOLOGY
- Clearance systems in the brain—implications for Alzheimer disease
- (2015) Jenna M. Tarasoff-Conway et al. Nature Reviews Neurology
- Aβ induces PUMA activation: a new mechanism for Aβ-mediated neuronal apoptosis
- (2015) Jie Feng et al. NEUROBIOLOGY OF AGING
- Appoptosin-Mediated Caspase Cleavage of Tau Contributes to Progressive Supranuclear Palsy Pathogenesis
- (2015) Yingjun Zhao et al. NEURON
- ESC-Derived Basal Forebrain Cholinergic Neurons Ameliorate the Cognitive Symptoms Associated with Alzheimer’s Disease in Mouse Models
- (2015) Wei Yue et al. Stem Cell Reports
- Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer’s disease
- (2014) M-S Tan et al. Cell Death & Disease
- Inactivation of BAD by IKK Inhibits TNFα-Induced Apoptosis Independently of NF-κB Activation
- (2013) Jie Yan et al. CELL
- Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation
- (2013) William A Eimer et al. Molecular Neurodegeneration
- Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
- (2013) Zhenyu Cai et al. NATURE CELL BIOLOGY
- Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis
- (2012) Kenichi Shimada et al. IMMUNITY
- Appoptosin is a Novel Pro-Apoptotic Protein and Mediates Cell Death in Neurodegeneration
- (2012) H. Zhang et al. JOURNAL OF NEUROSCIENCE
- PPAR /RXR -Induced and CD36-Mediated Microglial Amyloid- Phagocytosis Results in Cognitive Improvement in Amyloid Precursor Protein/Presenilin 1 Mice
- (2012) M. Yamanaka et al. JOURNAL OF NEUROSCIENCE
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicity
- (2012) W Kudo et al. Cell Death & Disease
- TLR2 Is a Primary Receptor for Alzheimer's Amyloid Peptide To Trigger Neuroinflammatory Activation
- (2011) S. Liu et al. JOURNAL OF IMMUNOLOGY
- The APP intracellular domain (AICD) potentiates ER stress-induced apoptosis
- (2011) Donat Kögel et al. NEUROBIOLOGY OF AGING
- Molecular mechanisms of neurodegeneration in Alzheimer's disease
- (2010) L. Crews et al. HUMAN MOLECULAR GENETICS
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- Probing the Biology of Alzheimer's Disease in Mice
- (2010) Karen H. Ashe et al. NEURON
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Amyloid β-Induced Nerve Growth Factor Dysmetabolism in Alzheimer Disease
- (2009) Martin A. Bruno et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease
- (2009) Alan H Nagahara et al. NATURE MEDICINE
- BAD: undertaker by night, candyman by day
- (2009) N N Danial ONCOGENE
- Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain
- (2009) K. Ghosal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lack of Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease after Overexpression of the Anti-Apoptotic Protein Bcl-2
- (2008) T. T. Rohn et al. JOURNAL OF NEUROSCIENCE
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β
- (2008) Annett Halle et al. NATURE IMMUNOLOGY
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