The BH3-only protein BAD mediates TNFα cytotoxicity despite concurrent activation of IKK and NF-κB in septic shock

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sepsis and septic shock

(2016) Richard S. Hotchkiss et al.   Nature Reviews Disease Primers

Super-resolution imaging for cell biologists

(2015) Eugenio F. Fornasiero et al.   BIOESSAYS

The BH3-only protein Bad is dispensable for TNF-mediated cell death

(2015) E Ottina et al.   Cell Death & Disease

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

(2014) James A. Rickard et al.   CELL

Regulation of Hepatic Energy Metabolism and Gluconeogenesis by BAD

(2014) Alfredo Giménez-Cassina et al.   Cell Metabolism

Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies

(2014) Bernhard Zatloukal et al.   PLoS One

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice

(2014) James A Rickard et al.   eLife

Inactivation of BAD by IKK Inhibits TNFα-Induced Apoptosis Independently of NF-κB Activation

(2013) Jie Yan et al.   CELL

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

(2013) Zhenyu Cai et al.   NATURE CELL BIOLOGY

Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding

(2013) Kendra N. Iskander et al.   PHYSIOLOGICAL REVIEWS

Tolerance of Infections

(2012) Janelle S. Ayres et al.   Annual Review of Immunology

Disease Tolerance as a Defense Strategy

(2012) R. Medzhitov et al.   SCIENCE

The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation

(2011) Marion C. Bonnet et al.   IMMUNITY

RhoA GTPase Is Dispensable for Actomyosin Regulation but Is Essential for Mitosis in Primary Mouse Embryonic Fibroblasts

(2011) Jaime Melendez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Epidermal Growth Factor Receptor Mediates Tumor Necrosis Factor-α-induced Activation of the ERK/GEF-H1/RhoA Pathway in Tubular Epithelium

(2011) Eli Kakiashvili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proximity ligation assays: a recent addition to the proteomics toolbox

(2010) Irene Weibrecht et al.   Expert Review of Proteomics

Tnf-α expression and promoter sequences reflect the balance of tolerance/resistance to Puumala hantavirus infection in European bank vole populations

(2010) Emmanuel Guivier et al.   INFECTION GENETICS AND EVOLUTION

Single-cell NF-κB dynamics reveal digital activation and analogue information processing

(2010) Savaş Tay et al.   NATURE

Overexpression of HO-1 Protects against TNF-α-Mediated Airway Inflammation by Down-Regulation of TNFR1-Dependent Oxidative Stress

(2009) I-Ta Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Crucial Role of TNF Receptors 1 and 2 in the Control of Polymicrobial Sepsis

(2009) T. Secher et al.   JOURNAL OF IMMUNOLOGY

Cytokine Polymorphisms and Severity of Tubal Damage in Women withChlamydia‐Associated Infertility

(2009) H. Öhman et al.   JOURNAL OF INFECTIOUS DISEASES

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

Phosphorylation of Bad at Thr-201 by JNK1 Promotes Glycolysis through Activation of Phosphofructokinase-1

(2008) Hongbin Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A microbial symbiosis factor prevents intestinal inflammatory disease

(2008) Sarkis K. Mazmanian et al.   NATURE

Decomposing health: tolerance and resistance to parasites in animals

(2008) L. Raberg et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY