The Molecular Interplay between Human Coronaviruses and Autophagy

Cytoplasmic short linear motifs in ACE2 and integrin β3 link SARS-CoV-2 host cell receptors to mediators of endocytosis and autophagy

(2021) Johanna Kliche et al.   Science Signaling

Lysosome activation in peripheral blood mononuclear cells and prognostic significance of circulating LC3B in COVID-19

(2021) Shisong Fang et al.   BRIEFINGS IN BIOINFORMATICS

Reduced Expression of Autophagy Markers and Expansion of Myeloid-Derived Suppressor Cells Correlate With Poor T Cell Response in Severe COVID-19 Patients

(2021) Sergej Tomić et al.   Frontiers in Immunology

SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway

(2021) Grant R. Campbell et al.   iScience

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

(2021) Alexey Stukalov et al.   NATURE

Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities

(2021) Manuel Hayn et al.   Cell Reports

The SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes

(2021) Yabin Zhang et al.   Cell Discovery

Beclin-1, an autophagy-related protein, is associated with the disease severity of COVID-19

(2021) Hamza Malik Okuyan et al.   LIFE SCIENCES

The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι

(2021) Yiwen Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding SARS‐CoV‐2 endocytosis for COVID‐19 drug repurposing

(2020) Oleg O. Glebov   FEBS Journal

Evolutionary analysis of SARS-CoV-2: how mutation of Non-Structural Protein 6 (NSP6) could affect viral autophagy

(2020) Domenico Benvenuto et al.   JOURNAL OF INFECTION

COVID‐19 patients' clinical characteristics, discharge rate, and fatality rate of meta‐analysis

(2020) Long‐quan Li et al.   JOURNAL OF MEDICAL VIROLOGY

Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1

(2020) Chengxin Zhang et al.   JOURNAL OF PROTEOME RESEARCH

The proximal origin of SARS-CoV-2

(2020) Kristian G. Andersen et al.   NATURE MEDICINE

Cell entry mechanisms of SARS-CoV-2

(2020) Jian Shang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 (COVID-19) by the numbers

(2020) Yinon M Bar-On et al.   eLife

Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype?

(2020) Patrick Brest et al.   Autophagy

Autophagy as an emerging target for COVID-19: lessons from an old friend, chloroquine

(2020) Srinivasa Reddy Bonam et al.   Autophagy

COVID-19, SARS and MERS: are they closely related?

(2020) N. Petrosillo et al.   CLINICAL MICROBIOLOGY AND INFECTION

Kurarinone Inhibits HCoV-OC43 Infection by Impairing the Virus-Induced Autophagic Flux in MRC-5 Human Lung Cells

(2020) Jung Sun Min et al.   Journal of Clinical Medicine

Suppression of SARS‐CoV‐2 infection in ex‐vivo human lung tissues by targeting class III phosphoinositide 3‐kinase

(2020) Chun‐Kit Yuen et al.   JOURNAL OF MEDICAL VIROLOGY

Autophagy Augmentation to Alleviate Immune Response Dysfunction, and Resolve Respiratory and COVID-19 Exacerbations

(2020) Garrett Pehote et al.   Cells

AR12 (OSU-03012) suppresses GRP78 expression and inhibits SARS-CoV-2 replication

(2020) Jonathan O. Rayner et al.   BIOCHEMICAL PHARMACOLOGY

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

(2020) Guangyan Miao et al.   DEVELOPMENTAL CELL

Dysregulation of the mevalonate pathway during SARS‐CoV‐2 infection: An in silico study

(2020) Juan Luis Gomez Marti et al.   JOURNAL OF MEDICAL VIROLOGY

A cross-talk between epithelium and endothelium mediates human alveolar–capillary injury during SARS-CoV-2 infection

(2020) Peng Wang et al.   Cell Death & Disease

The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules

(2020) Kirill Gorshkov et al.   ACS Infectious Diseases

Taming the Autophagy as a Strategy for Treating COVID-19

(2020) Blanca Estela García-Pérez et al.   Cells

Human Coronavirus: Host-Pathogen Interaction

(2019) To Sing Fung et al.   Annual Review of Microbiology

SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

(2019) Nils C. Gassen et al.   Nature Communications

SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death

(2018) Yuan Yue et al.   Cell Death & Disease

Autophagosome maturation: An epic journey from the ER to lysosomes

(2018) Yan G. Zhao et al.   JOURNAL OF CELL BIOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Coronavirus NSP6 restricts autophagosome expansion

(2014) Eleanor M Cottam et al.   Autophagy

SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome

(2014) Chong-Shan Shi et al.   JOURNAL OF IMMUNOLOGY

Coronavirus membrane-associated papain-like proteases induce autophagy through interacting with Beclin1 to negatively regulate antiviral innate immunity

(2014) Xiaojuan Chen et al.   Protein & Cell

Severe Acute Respiratory Syndrome Coronavirus Replication Is Severely Impaired by MG132 due to Proteasome-Independent Inhibition of M-Calpain

(2012) Martha Schneider et al.   JOURNAL OF VIROLOGY

Coronavirus nsp6 proteins generate autophagosomes from the endoplasmic reticulum via an omegasome intermediate

(2011) Eleanor M. Cottam et al.   Autophagy

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Autophagy and the ubiquitin-proteasome system: Collaborators in neuroprotection

(2008) Natalia B. Nedelsky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE