Neutrophil Extracellular Trap-Driven Occlusive Diseases

The Inhibitory Effect of Curosurf® and Alveofact® on the Formation of Neutrophil Extracellular Traps

(2021) Annabell Schulz et al.   Frontiers in Immunology

Neutrophil-lymphocyte ratio acts as a novel diagnostic biomarker for kidney stone prevalence and number of stones passed

(2021) Weipu Mao et al.   Translational Andrology and Urology

Metabolomics of gingival crevicular fluid to identify biomarkers for periodontitis: A systematic review with meta‐analysis

(2021) Giacomo Baima et al.   JOURNAL OF PERIODONTAL RESEARCH

Gingival Crevicular Fluid (GCF): A Diagnostic Tool for the Detection of Periodontal Health and Diseases

(2021) Tauqeer Bibi et al.   MOLECULES

The Balance of Neutrophil Extracellular Trap Formation and Nuclease Degradation: an Unknown Role of Bacterial Coinfections in COVID-19 Patients?

(2021) Nicole de Buhr et al.   mBio

Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke

(2021) Ranran Wang et al.   BLOOD

The Neutrophil Secretome as a Crucial Link between Inflammation and Thrombosis

(2021) María Amparo Blanch-Ruiz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ICODE: the international COVID-19 thrombosis biomarkers colloquium—novel soluble biomarkers: circulating cell-free nucleic acids and other molecules

(2021) Krystin Krauel et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Pathophysiology of Meibomian Glands – An Overview

(2021) Jana Dietrich et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Aggregated neutrophil extracellular traps occlude Meibomian glands during ocular surface inflammation

(2021) Aparna Mahajan et al.   Ocular Surface

The Role of Neutrophil Extracellular Traps in Periodontitis

(2021) Jingyi Wang et al.   Frontiers in Cellular and Infection Microbiology

Phagocytosis, Degranulation and Extracellular Traps Release by Neutrophils—The Current Knowledge, Pharmacological Modulation and Future Prospects

(2021) Barbara Gierlikowska et al.   Frontiers in Pharmacology

Neutrophil Extracellular Traps in the Autoimmunity Context

(2021) Maurizio Bruschi et al.   Frontiers in Medicine

Local, non-systemic, and minimally invasive therapies for calcinosis cutis: a systematic review

(2021) Joanna Nowaczyk et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Patients with COVID-19: in the dark-NETs of neutrophils

(2021) Maximilian Ackermann et al.   CELL DEATH AND DIFFERENTIATION

Interactions between neutrophil extracellular traps and activated platelets enhance procoagulant activity in acute stroke patients with ICA occlusion

(2020) Peng Zhou et al.   EBioMedicine

Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism

(2020) Chongxu Shi et al.   CIRCULATION RESEARCH

Targeting potential drivers of COVID-19: Neutrophil extracellular traps

(2020) Betsy J. Barnes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Post-operative morbidity following pancreatic duct occlusion without anastomosis after pancreaticoduodenectomy: a systematic review and meta-analysis

(2020) Mariano C. Giglio et al.   HPB

The Red Blood Cell—Inflammation Vicious Circle in Sickle Cell Disease

(2020) Elie Nader et al.   Frontiers in Immunology

Cellular Mechanisms of NETosis

(2020) Hawa Racine Thiam et al.   Annual Review of Cell and Developmental Biology

miR-146a is a pivotal regulator of neutrophil extracellular trap formation promoting thrombosis

(2020) Ana B. Arroyo et al.   HAEMATOLOGICA

The neutrophil subset defined by CD177 expression is preferentially recruited to gingival crevicular fluid in periodontitis

(2020) Agnes Dahlstrand Rudin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Vascular occlusion by neutrophil extracellular traps in COVID-19

(2020) Moritz Leppkes et al.   EBioMedicine

Neutrophil Extracellular Traps in Periodontitis

(2020) Antonio Magán-Fernández et al.   Cells

A Precision Medicine Approach Uncovers a Unique Signature of Neutrophils in Patients With Brushite Kidney Stones

(2020) Mohammad Shahidul Makki et al.   Kidney International Reports

Immunohistological Analysis of Neutrophils and Neutrophil Extracellular Traps in Human Thrombemboli Causing Acute Ischemic Stroke

(2020) Fabian Essig et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

(2020) Panagiotis Skendros et al.   JOURNAL OF CLINICAL INVESTIGATION

Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19

(2020) Coraline Radermecker et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology

(2020) Flavio Protasio Veras et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Netting Liver Disease: Neutrophil Extracellular Traps in the Initiation and Exacerbation of Liver Pathology

(2020) Fien A. von Meijenfeldt et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Neutrophil Extracellular Traps Promote the Development and Growth of Human Salivary Stones

(2020) Mirco Schapher et al.   Cells

Inhibition of Peptidyl Arginine Deiminase-4 Prevents Renal Ischemia-Reperfusion-Induced Remote Lung Injury

(2020) Mingjun Du et al.   MEDIATORS OF INFLAMMATION

Classification of submandibular salivary stones based on ultrastructural studies

(2020) Dmitry Tretiakow et al.   ORAL DISEASES

Neutrophil Inflammatory Response Is Downregulated by Uptake of Superparamagnetic Iron Oxide Nanoparticle Therapeutics

(2020) Gustavo Garcia et al.   Frontiers in Immunology

Assessment of Neutrophil Extracellular Traps in Coronary Thrombus of a Case Series of Patients With COVID-19 and Myocardial Infarction

(2020) Ana Blasco et al.   JAMA Cardiology

NETs Are Double-Edged Swords with the Potential to Aggravate or Resolve Periodontal Inflammation

(2020) Ljubomir Vitkov et al.   Cells

Fibrin Modulates Shear-Induced NETosis in Sterile Occlusive Thrombi Formed under Haemodynamic Flow

(2019) Xinren Yu et al.   THROMBOSIS AND HAEMOSTASIS

Evidence of a microbial etiology for sialoliths

(2019) Wee Tin K. Kao et al.   LARYNGOSCOPE

Neutrophils: back in the thrombosis spotlight

(2019) Denis F. Noubouossie et al.   BLOOD

Frontline Science: Aggregated neutrophil extracellular traps prevent inflammation on the neutrophil‐rich ocular surface

(2019) Aparna Mahajan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophil Extracellular Traps

(2019) Charlotte Thålin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Plasma Peptidylarginine Deiminase IV Promotes VWF-Platelet String Formation and Accelerates Thrombosis after Vessel Injury

(2019) Nicoletta Sorvillo et al.   CIRCULATION RESEARCH

Extracellular DNA traps in inflammation, injury and healing

(2019) Christoph Daniel et al.   Nature Reviews Nephrology

Editorial: Nano- and Microparticle-Induced Cell Death, Inflammation and Immune Responses

(2019) Shrikant R. Mulay et al.   Frontiers in Immunology

NETched in Stone

(2019) Liam J. O’Neil et al.   IMMUNITY

Neutrophil Extracellular Traps Initiate Gallstone Formation

(2019) Luis E. Muñoz et al.   IMMUNITY

Treatment with DNases rescues hidden neutrophil elastase from aggregated NETs

(2019) Malgorzata J. Podolska et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance

(2019) Carolina Peña-Martínez et al.   STROKE

Management of Meibomian Gland Dysfunction: A Review

(2019) Saama Sabeti et al.   SURVEY OF OPHTHALMOLOGY

Neutrophil Extracellular Traps: Current Perspectives in the Eye

(2019) Gibrán Alejandro Estúa-Acosta et al.   Cells

Neutrophil Extracellular Trap Formation: Physiology, Pathology, and Pharmacology

(2019) Mithunan Ravindran et al.   Biomolecules

Neutrophil extracellular traps and dsDNA predict outcomes among patients with ST-elevation myocardial infarction

(2019) Jing Liu et al.   Scientific Reports

Neutrophil extracellular traps drive inflammatory pathogenesis in malaria

(2019) Sebastian Lorenz Knackstedt et al.   Science Immunology

Signal inhibitory receptor on leukocytes (SIRL)-1 and leukocyte- associated immunoglobulin-like receptor (LAIR)-1 regulate neutrophil function in infants

(2019) Sjanna B. Besteman et al.   CLINICAL IMMUNOLOGY

Pro-inflammatory cytokines associate with NETosis during sickle cell vaso-occlusive crises

(2019) Emilia A Barbu et al.   CYTOKINE

Neutrophils remain detrimentally active in hydroxyurea-treated patients with sickle cell disease

(2019) Emilia Alina Barbu et al.   PLoS One

Updates on NET formation in health and disease

(2019) Moritz Leppkes et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio can predict the severity of gallstone pancreatitis

(2018) Seung Kook Cho et al.   BMC GASTROENTEROLOGY

Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity

(2018) Daniel S Gaul et al.   CARDIOVASCULAR RESEARCH

Autonomic nervous system involvement in sickle cell disease

(2018) Thomas D. Coates et al.   CLINICAL HEMORHEOLOGY AND MICROCIRCULATION

Beginnings of nephrolithiasis

(2018) Scott V. Wiener et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging

(2018) Siu Ling Wong et al.   FASEB JOURNAL

Imaging of Inflammatory Disorders of Salivary Glands

(2018) Asim K. Bag et al.   NEUROIMAGING CLINICS OF NORTH AMERICA

Neutrophil extracellular traps possess anti-human respiratory syncytial virus activity: Possible interaction with the viral F protein

(2018) Priscila Silva Sampaio Souza et al.   VIRUS RESEARCH

Red blood cells are dynamic reservoirs of cytokines

(2018) Elisabeth Karsten et al.   Scientific Reports

Roles of PAD4 and netosis in experimental atherosclerosis and arterial injury: Implications for superficial erosion

(2018) G. Franck et al.   ATHEROSCLEROSIS

Aggregated neutrophil extracellular traps resolve inflammation by proteolysis of cytokines and chemokines and protection from antiproteases

(2018) Jonas Hahn et al.   FASEB JOURNAL

The role of neutrophils in thrombosis

(2018) Sargam Kapoor et al.   THROMBOSIS RESEARCH

Respiratory Syncytial Virus induces the classical ROS-dependent NETosis through PAD-4 and necroptosis pathways activation

(2018) Stéfanie P. Muraro et al.   Scientific Reports

Biochemical composition of salivary stones in relation to stone- and patient-related factors

(2018) S Kraaij et al.   Medicina Oral Patologia Oral y Cirugia Bucal

Targeting peptidylarginine deiminase reduces neutrophil extracellular trap formation and tissue injury in severe acute pancreatitis

(2018) Raed Madhi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Inert Coats of Magnetic Nanoparticles Prevent Formation of Occlusive Intravascular Co-aggregates With Neutrophil Extracellular Traps

(2018) Rostyslav Bilyy et al.   Frontiers in Immunology

Meibomian Gland Disease

(2017) Priyanka Chhadva et al.   OPHTHALMOLOGY

Host DNases prevent vascular occlusion by neutrophil extracellular traps

(2017) Miguel Jiménez-Alcázar et al.   SCIENCE

Local dornase alfa treatment reduces NETs-induced airway obstruction during severe RSV infection

(2017) Bart Cortjens et al.   THORAX

Particles of different sizes and shapes induce neutrophil necroptosis followed by the release of neutrophil extracellular trap-like chromatin

(2017) Jyaysi Desai et al.   Scientific Reports

Neutrophil Extracellular Traps Open the Pandora’s Box in Severe Malaria

(2017) Sebastian Boeltz et al.   Frontiers in Immunology

Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice

(2016) K. Stark et al.   BLOOD

Bacterial Biofilm in Salivary Gland Stones

(2016) Massimo Fusconi et al.   OTOLARYNGOLOGY-HEAD AND NECK SURGERY

Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation

(2016) Luis E. Muñoz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis

(2016) Moritz Leppkes et al.   Nature Communications

Ménage-à-Trois: The Ratio of Bicarbonate to CO2 and the pH Regulate the Capacity of Neutrophils to Form NETs

(2016) Christian Maueröder et al.   Frontiers in Immunology

Oxidative Burst-Dependent NETosis Is Implicated in the Resolution of Necrosis-Associated Sterile Inflammation

(2016) Mona H. C. Biermann et al.   Frontiers in Immunology

Complement Activation in Arterial and Venous Thrombosis is Mediated by Plasmin

(2016) Jonathan H. Foley et al.   EBioMedicine

Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction

(2015) Dimitrios A. Stakos et al.   EUROPEAN HEART JOURNAL

Histopathological evaluation of thrombus in patients presenting with stent thrombosis. A multicenter European study: a report of the prevention of late stent thrombosis by an interdisciplinary global European effort consortium

(2015) Julia Riegger et al.   EUROPEAN HEART JOURNAL

Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice With Severe Acute Pancreatitis

(2015) Mohammed Merza et al.   GASTROENTEROLOGY

Neutrophil extracellular traps cause airway obstruction during respiratory syncytial virus disease

(2015) Bart Cortjens et al.   JOURNAL OF PATHOLOGY

Extracellular DNA and histones: double-edged swords in immunothrombosis

(2015) T. J. Gould et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Respiratory Syncytial Virus Fusion Protein Promotes TLR-4–Dependent Neutrophil Extracellular Trap Formation by Human Neutrophils

(2015) Giselle A. Funchal et al.   PLoS One

Neutrophil recruitment to the brain in mouse and human ischemic stroke

(2014) Isabel Perez-de-Puig et al.   ACTA NEUROPATHOLOGICA

Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis

(2014) Jason S. Knight et al.   CIRCULATION RESEARCH

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines

(2014) Christine Schauer et al.   NATURE MEDICINE

Biological basis and pathological relevance of microvascular thrombosis

(2014) Susanne Pfeiler et al.   THROMBOSIS RESEARCH

Randall’s plaque as the origin of calcium oxalate kidney stones

(2014) Michel Daudon et al.   Urolithiasis

Nucleosomes and neutrophil activation in sickle cell disease painful crisis

(2013) M. Schimmel et al.   HAEMATOLOGICA

Neutrophils, neutrophil extracellular traps and interleukin-17 associate with the organisation of thrombi in acute myocardial infarction

(2012) Xiaofei Li et al.   THROMBOSIS AND HAEMOSTASIS

Myeloperoxidase is required for neutrophil extracellular trap formation: implications for innate immunity

(2010) K. D. Metzler et al.   BLOOD

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local complement activation triggers neutrophil recruitment to the site of thrombus formation in acute myocardial infarction

(2009) Klaus Distelmaier et al.   THROMBOSIS AND HAEMOSTASIS