Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk
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Title
Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk
Authors
Keywords
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Journal
Acta Pharmaceutica Sinica B
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-08-27
DOI
10.1016/j.apsb.2021.08.024
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Note: Only part of the references are listed.- The development and hepatotoxicity of acetaminophen: reviewing over a century of progress
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- A direct comparison of methods used to measure oxidized glutathione in biological samples: 2-vinylpyridine andN-ethylmaleimide
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- HepaRG cells: A human model to study mechanisms of acetaminophen hepatotoxicity
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