Silencing Glycogen Synthase Kinase-3β Inhibits Acetaminophen Hepatotoxicity and Attenuates JNK Activation and Loss of Glutamate Cysteine Ligase and Myeloid Cell Leukemia Sequence 1

Redox Regulation of Tumor Necrosis Factor Signaling

(2009) Derick Han et al.   ANTIOXIDANTS & REDOX SIGNALING

Antiapoptotic Effect of c-Jun N-terminal Kinase-1 through Mcl-1 Stabilization in TNF-Induced Hepatocyte Apoptosis

(2009) Yuzo Kodama et al.   GASTROENTEROLOGY

Drug Development Targeting the Glycogen Synthase Kinase-3β (GSK-3β)-Mediated Signal Transduction Pathway: Role of GSK-3β in Myocardial Protection Against Ischemia/Reperfusion Injury

(2009) Tetsuji Miura et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Regulation of H2O2-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes

(2008) Behnam Saberi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

c-Jun N-terminal kinase 1 interacts with and negatively regulates Wnt/ -catenin signaling through GSK3  pathway

(2008) D. Hu et al.   CARCINOGENESIS

Unique Biology of Mcl-1: Therapeutic Opportunities in Cancer

(2008) Gordon Shore et al.   CURRENT MOLECULAR MEDICINE

How to Protect Against Acetaminophen: Don't Ask for JUNK

(2008) Neil Kaplowitz et al.   GASTROENTEROLOGY

Deletion of Apoptosis Signal-Regulating Kinase 1 Attenuates Acetaminophen-Induced Liver Injury by Inhibiting c-Jun N-Terminal Kinase Activation

(2008) Hayato Nakagawa et al.   GASTROENTEROLOGY

The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system

(2008) Ian M. Copple et al.   HEPATOLOGY

Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes

(2008) Binje Vick et al.   HEPATOLOGY

Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

(2008) Naoko Hanawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY