The Role and Mechanism of Pyroptosis and Potential Therapeutic Targets in Sepsis: A Review
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The Role and Mechanism of Pyroptosis and Potential Therapeutic Targets in Sepsis: A Review
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-07-07
DOI
10.3389/fimmu.2021.711939
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Nitrosonisoldipine is a selective inhibitor of inflammatory caspases and protects against pyroptosis and related septic shock
- (2021) Qianyue Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic-Acute Kidney Injury In Vivo
- (2020) Zhuang Wang et al. JOURNAL OF IMMUNOLOGY
- TMEM173 Drives Lethal Coagulation in Sepsis
- (2020) Hui Zhang et al. Cell Host & Microbe
- Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation
- (2020) Xiaorong Hou et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Ginsenoside metabolite 20(S)-protopanaxatriol from Panax ginseng attenuates inflammation-mediated NLRP3 inflammasome activation
- (2020) Jun Jiang et al. JOURNAL OF ETHNOPHARMACOLOGY
- PECAM-1 protects against DIC by dampening inflammatory responses via inhibiting macrophage pyroptosis and restoring vascular barrier integrity
- (2020) Lili Luo et al. Translational Research
- Antecedent Dietary Glutamine Supplementation Benefits Modulation of Liver Pyroptosis in Mice with Polymicrobial Sepsis
- (2020) Man-Hui Pai et al. Nutrients
- Therapeutic Potential of Cathelicidin Peptide LL-37, an Antimicrobial Agent, in a Murine Sepsis Model
- (2020) Isao Nagaoka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CXADR‐like membrane protein protects against heart injury by preventing excessive pyroptosis after myocardial infarction
- (2020) Xinglong Han et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Estrogen protects against liver damage in sepsis through inhibiting oxidative stress mediated activation of pyroptosis signaling pathway
- (2020) Zihan Xu et al. PLoS One
- HMGB1 suppress the expression of IL-35 by regulating Naïve CD4+ T cell differentiation and aggravating Caspase-11-dependent pyroptosis in acute lung injury
- (2020) Ke Xie et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Dihydromyricetin Alleviates Sepsis-Induced Acute Lung Injury through Inhibiting NLRP3 Inflammasome-Dependent Pyroptosis in Mice Model
- (2019) Yu-chang Wang et al. INFLAMMATION
- Caspase-1 inhibitor exerts brain-protective effects against sepsis-associated encephalopathy and cognitive impairments in a mouse model of sepsis
- (2019) Xi-e Xu et al. BRAIN BEHAVIOR AND IMMUNITY
- cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis
- (2019) Ruochan Chen et al. Science Advances
- Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury
- (2019) Zhiming Ye et al. KIDNEY & BLOOD PRESSURE RESEARCH
- miR-21 promotes NLRP3 inflammasome activation to mediate pyroptosis and endotoxic shock
- (2019) Zhenyi Xue et al. Cell Death & Disease
- STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3
- (2019) Ning Li et al. Redox Biology
- Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure
- (2019) Xinyu Yang et al. IMMUNITY
- Sphingosine-1-phosphate Receptor 2 Signaling Promotes Caspase-11–dependent Macrophage Pyroptosis and Worsens Escherichia coli Sepsis Outcome
- (2018) Fang Song et al. ANESTHESIOLOGY
- Mechanisms of Gasdermin Family Members in Inflammasome Signaling and Cell Death
- (2018) Shouya Feng et al. JOURNAL OF MOLECULAR BIOLOGY
- Targeting Peroxiredoxin 1 by a Curcumin Analogue, AI-44, Inhibits NLRP3 Inflammasome Activation and Attenuates Lipopolysaccharide-Induced Sepsis in Mice
- (2018) Wen Liu et al. JOURNAL OF IMMUNOLOGY
- The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis
- (2018) Meihong Deng et al. IMMUNITY
- Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
- (2018) Joseph Sarhan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death
- (2018) Pontus Orning et al. SCIENCE
- Myricetin inhibits NLRP3 inflammasome activation via reduction of ROS-dependent ubiquitination of ASC and promotion of ROS-independent NLRP3 ubiquitination
- (2018) Hanwen Chen et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Inhibition of NLRP3 inflammasome: a new protective mechanism of cinnamaldehyde in endotoxin poisoning of mice
- (2017) Feng Xu et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury
- (2017) Kwong Tai Cheng et al. JOURNAL OF CLINICAL INVESTIGATION
- Protective effects of Cinnamomum cassia (Lamaceae) against gout and septic responses via attenuation of inflammasome activation in experimental models
- (2017) Woo-Young Shin et al. JOURNAL OF ETHNOPHARMACOLOGY
- Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis inPseudomonasSepsis
- (2017) Qinqin Pu et al. JOURNAL OF IMMUNOLOGY
- Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis
- (2017) Ibtissem Rahim et al. JOURNAL OF PINEAL RESEARCH
- Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
- (2017) Yupeng Wang et al. NATURE
- Comparison of the Performance Between Sepsis-1 and Sepsis-3 in ICUs in China
- (2017) Baoli Cheng et al. SHOCK
- Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
- (2017) Jianjin Shi et al. TRENDS IN BIOCHEMICAL SCIENCES
- Gasdermins: Effectors of Pyroptosis
- (2017) Stephen B. Kovacs et al. TRENDS IN CELL BIOLOGY
- Recent Insights into the Molecular Mechanisms Underlying Pyroptosis and Gasdermin Family Functions
- (2017) Robin A. Aglietti et al. TRENDS IN IMMUNOLOGY
- Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
- (2017) Corey Rogers et al. Nature Communications
- Sepsis: in search of cure
- (2016) Chikkamenahalli Lakshminarayana Lakshmikanth et al. INFLAMMATION RESEARCH
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- (2016) Mervyn Singer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
- (2016) Xing Liu et al. NATURE
- Neutrophil P2X7 receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP
- (2016) Mausita Karmakar et al. Nature Communications
- Gasdermin D: the long-awaited executioner of pyroptosis
- (2015) Si Ming Man et al. CELL RESEARCH
- Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion
- (2015) Wan-ting He et al. CELL RESEARCH
- Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock
- (2015) Dahai Yang et al. IMMUNITY
- Pyroptotic cell death defends against intracellular pathogens
- (2015) Ine Jorgensen et al. IMMUNOLOGICAL REVIEWS
- Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+Efflux
- (2015) Mausita Karmakar et al. JOURNAL OF IMMUNOLOGY
- Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
- (2015) Nobuhiko Kayagaki et al. NATURE
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- Systemic Inflammatory Response Syndrome Criteria in Defining Severe Sepsis
- (2015) Kirsi-Maija Kaukonen et al. NEW ENGLAND JOURNAL OF MEDICINE
- NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases
- (2015) Amna Abderrazak et al. Redox Biology
- Multiple Nod-Like Receptors Activate Caspase 1 during Listeria monocytogenes Infection
- (2014) S. E. Warren et al. JOURNAL OF IMMUNOLOGY
- Inflammatory caspases are innate immune receptors for intracellular LPS
- (2014) Jianjin Shi et al. NATURE
- Revisiting caspases in sepsis
- (2014) M Aziz et al. Cell Death & Disease
- Caspase-11 Protects Against Bacteria That Escape the Vacuole
- (2013) Y. Aachoui et al. SCIENCE
- Caspase-8 Blocks Kinase RIPK3-Mediated Activation of the NLRP3 Inflammasome
- (2012) Tae-Bong Kang et al. IMMUNITY
- Current trends in inflammatory and immunomodulatory mediators in sepsis
- (2012) M. Aziz et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Caspase-1-induced pyroptotic cell death
- (2011) Edward A. Miao et al. IMMUNOLOGICAL REVIEWS
- Non-canonical inflammasome activation targets caspase-11
- (2011) Nobuhiko Kayagaki et al. NATURE
- The Inflammasomes
- (2010) Kate Schroder et al. CELL
- Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes
- (2010) Jianghong Wu et al. JOURNAL OF CLINICAL IMMUNOLOGY
- The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
- (2010) Teresa Fernandes-Alnemri et al. NATURE IMMUNOLOGY
- Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria
- (2010) Edward A Miao et al. NATURE IMMUNOLOGY
- Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome
- (2009) Kate Schroder et al. CURRENT BIOLOGY
- Signaling at Purinergic P2X Receptors
- (2008) Annmarie Surprenant et al. Annual Review of Physiology
- Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
- (2008) S. L. Fink et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started