Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19

Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients

(2020) Xiaohua Chen et al.   CLINICAL INFECTIOUS DISEASES

COVID-19: consider cytokine storm syndromes and immunosuppression

(2020) Puja Mehta et al.   LANCET

Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19

(2020) Yan Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine

(2020) Anna Z. Wec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV

(2020) Meng Yuan et al.   SCIENCE

B Cell Activation and Response Regulation During Viral Infections

(2020) Jonathan H. Lam et al.   VIRAL IMMUNOLOGY

On the Alert for Cytokine Storm: Immunopathology in COVID ‐19

(2020) Lauren A. Henderson et al.   Arthritis & Rheumatology

Immunomodulation in COVID-19

(2020) Nicholas E Ingraham et al.   Lancet Respiratory Medicine

Persistent Symptoms in Patients After Acute COVID-19

(2020) Angelo Carfì et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Longitudinal analyses reveal immunological misfiring in severe COVID-19

(2020) Carolina Lucas et al.   NATURE

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

(2020) Lihong Liu et al.   NATURE

Potently neutralizing and protective human antibodies against SARS-CoV-2

(2020) Seth J. Zost et al.   NATURE

Focus shifts to antibody cocktails for COVID-19 cytokine storm

(2020) Charlotte Harrison   NATURE BIOTECHNOLOGY

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

(2020) Quan-Xin Long et al.   NATURE MEDICINE

Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19

(2020) F. Javier Ibarrondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

(2020) Divij Mathew et al.   SCIENCE

Brief Report: Anti‐phospholipid antibodies in critically ill patients with Coronavirus Disease 2019 (COVID‐19)

(2020) Meng Xiao et al.   Arthritis & Rheumatology

Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies

(2020) Yujun Tang et al.   Frontiers in Immunology

GLaMST: grow lineages along minimum spanning tree for b cell receptor sequencing data

(2020) Xingyu Yang et al.   BMC GENOMICS

Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19

(2020) Naoki Kaneko et al.   CELL

The continuing story of T‐cell independent antibodies

(2019) David Allman et al.   IMMUNOLOGICAL REVIEWS

Extrafollicular responses in humans and SLE

(2019) Scott A. Jenks et al.   IMMUNOLOGICAL REVIEWS

T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells

(2019) Sara L. Stone et al.   IMMUNITY

IFNγ induces epigenetic programming of human T-bethi B cells and promotesTLR7/8 and IL-21 induced differentiation

(2019) Esther Zumaquero et al.   eLife

The REDCap consortium: Building an international community of software platform partners

(2019) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Epigenetic programming underpins B cell dysfunction in human SLE

(2019) Christopher D. Scharer et al.   NATURE IMMUNOLOGY

Excessive CD11c+Tbet+ B cells promote aberrant TFH differentiation and affinity-based germinal center selection in lupus

(2019) Wenqian Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Challenges and Opportunities for Consistent Classification of Human B Cell and Plasma Cell Populations

(2019) Ignacio Sanz et al.   Frontiers in Immunology

Plasma Cells, the Next Generation: Beyond Antibody Secretion

(2019) Peter D. Pioli   Frontiers in Immunology

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells

(2018) Mauro Gaya et al.   CELL

Understanding B-cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B-cell immunomics approach

(2018) Christopher M. Tipton et al.   IMMUNOLOGICAL REVIEWS

Septic Shock Shapes B Cell Response toward an Exhausted-like/Immunoregulatory Profile in Patients

(2018) Claude-Alexandre Gustave et al.   JOURNAL OF IMMUNOLOGY

Regulation of age-associated B cells by IRF5 in systemic autoimmunity

(2018) Michela Manni et al.   NATURE IMMUNOLOGY

IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE

(2018) Shu Wang et al.   Nature Communications

FMST: an Automatic Neuron Tracing Method Based on Fast Marching and Minimum Spanning Tree

(2018) Jian Yang et al.   NEUROINFORMATICS

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

(2018) Scott A. Jenks et al.   IMMUNITY

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

B cells expressing the transcription factor T-bet drive lupus-like autoimmunity

(2017) Kira Rubtsova et al.   JOURNAL OF CLINICAL INVESTIGATION

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

(2016) Joanne H. Reed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation

(2015) Roberto Di Niro et al.   IMMUNITY

Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity

(2015) Kira Rubtsova et al.   JOURNAL OF IMMUNOLOGY

CD11c-Expressing B Cells Are Located at the T Cell/B Cell Border in Spleen and Are Potent APCs

(2015) Anatoly V. Rubtsov et al.   JOURNAL OF IMMUNOLOGY

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

(2015) Christopher M Tipton et al.   NATURE IMMUNOLOGY

Dengue Virus Infection Induces Expansion of a CD14+CD16+ Monocyte Population that Stimulates Plasmablast Differentiation

(2014) Marcin Kwissa et al.   Cell Host & Microbe

From the regulatory functions of B cells to the identification of cytokine-producing plasma cell subsets

(2014) Van Duc Dang et al.   CURRENT OPINION IN IMMUNOLOGY

B cells mediate chronic allograft rejection independently of antibody production

(2014) Qiang Zeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid and Massive Virus-Specific Plasmablast Responses during Acute Dengue Virus Infection in Humans

(2012) J. Wrammert et al.   JOURNAL OF VIROLOGY

Blood memory B cells are disturbed and predict the response to rituximab in patients with rheumatoid arthritis

(2011) Jérémie Sellam et al.   ARTHRITIS AND RHEUMATISM

Circulating Human Antibody-Secreting Cells during Vaccinations and Respiratory Viral Infections Are Characterized by High Specificity and Lack of Bystander Effect

(2011) F. E.-H. Lee et al.   JOURNAL OF IMMUNOLOGY

Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients

(2010) Beatriz Rodríguez-Bayona et al.   ARTHRITIS RESEARCH & THERAPY

Annexin A2 on lung epithelial cell surface is recognized by severe acute respiratory syndrome-associated coronavirus spike domain 2 antibodies

(2009) Yi-Ting Fang et al.   MOLECULAR IMMUNOLOGY