Intestinal dysbiosis and probiotic applications in autoimmune diseases

Influence of the Gut Microbiome on Autoimmunity in the Central Nervous System

(2017) Sara L. Colpitts et al.   JOURNAL OF IMMUNOLOGY

The Influence of the Microbiome on Type 1 Diabetes

(2017) Alexandra Paun et al.   JOURNAL OF IMMUNOLOGY

The role of the gastrointestinal tract in the pathogenesis of rheumatic diseases

(2016) Francesco Ciccia et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Clinical and metabolic response to probiotic supplementation in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial

(2016) Batol Zamani et al.   International Journal of Rheumatic Diseases

A clinical update on the significance of the gut microbiota in systemic autoimmunity

(2016) Elizabeth C. Rosser et al.   JOURNAL OF AUTOIMMUNITY

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

New insights into the immunopathogenesis of systemic lupus erythematosus

(2016) George C. Tsokos et al.   Nature Reviews Rheumatology

The global burden of SLE: prevalence, health disparities and socioeconomic impact

(2016) Erin E. Carter et al.   Nature Reviews Rheumatology

How the microbiota shapes rheumatic diseases

(2016) Tom Van de Wiele et al.   Nature Reviews Rheumatology

Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice

(2016) Tze Guan Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

Alterations of the gut microbiome in Chinese patients with systemic lupus erythematosus

(2016) Zhixing He et al.   Gut Pathogens

An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis

(2016) Jun Chen et al.   Genome Medicine

The effects of orally administered Bacillus coagulans and inulin on prevention and progression of rheumatoid arthritis in rats

(2016) Khadijeh Abhari et al.   Food & Nutrition Research

Alteration of Fecal Microbiota Profiles in Juvenile Idiopathic Arthritis. Associations with HLA-B27 Allele and Disease Status

(2016) Monica Di Paola et al.   Frontiers in Microbiology

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

(2016) Audrey Rivière et al.   Frontiers in Microbiology

Dysbiosis May Trigger Autoimmune Diseases via Inappropriate Post-Translational Modification of Host Proteins

(2016) Aaron Lerner et al.   Frontiers in Microbiology

Oral Probiotic VSL#3 Prevents Autoimmune Diabetes by Modulating Microbiota and Promoting Indoleamine 2,3-Dioxygenase-Enriched Tolerogenic Intestinal Environment

(2016) Jayashree Dolpady et al.   Journal of Diabetes Research

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study

(2016) Ulla Uusitalo et al.   JAMA Pediatrics

Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine

(2016) Yuichi Maeda et al.   Arthritis & Rheumatology

Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

(2016) Jun Chen et al.   Scientific Reports

Th17 responses and natural IgM antibodies are related to gut microbiota composition in systemic lupus erythematosus patients

(2016) Patricia López et al.   Scientific Reports

Role of the Gut Microbiome in Modulating Arthritis Progression in Mice

(2016) Xiaofei Liu et al.   Scientific Reports

The Dynamics of the Human Infant Gut Microbiome in Development and in Progression toward Type 1 Diabetes

(2015) Aleksandar D. Kostic et al.   Cell Host & Microbe

Immune homeostasis, dysbiosis and therapeutic modulation of the gut microbiota

(2015) C. T. Peterson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Impact of dietary deviation on disease progression and gut microbiome composition in lupus-prone SNF1mice

(2015) B. M. Johnson et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The influence of diet on the gut microbiota and its consequences for health

(2015) Joël Doré et al.   CURRENT OPINION IN BIOTECHNOLOGY

The Gut Microbiome in Multiple Sclerosis

(2015) Daniel W. Mielcarz et al.   Current Treatment Options in Neurology

Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes

(2015) Aimon K. Alkanani et al.   DIABETES

Commensal microbiota influence systemic autoimmune responses

(2015) J. T. Van Praet et al.   EMBO JOURNAL

Microbiota and host immune responses: a love-hate relationship

(2015) Sarah Tomkovich et al.   IMMUNOLOGY

Immunogenetic control of the intestinal microbiota

(2015) Eric Marietta et al.   IMMUNOLOGY

Gut Microbiota in Multiple Sclerosis

(2015) Brandi L. Cantarel et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Gut biogeography of the bacterial microbiota

(2015) Gregory P. Donaldson et al.   NATURE REVIEWS MICROBIOLOGY

The role for gut permeability in the pathogenesis of type 1 diabetes - a solid or leaky concept?

(2015) Xia Li et al.   PEDIATRIC DIABETES

Type 1 diabetes and gut microbiota: Friend or foe?

(2015) Changyun Hu et al.   PHARMACOLOGICAL RESEARCH

Peritoneal Cavity is a Route for Gut-Derived Microbial Signals to Promote Autoimmunity in Non-Obese Diabetic Mice

(2015) R. Emani et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Toll-Like Receptor Mediated Modulation of T Cell Response by Commensal Intestinal Microbiota as a Trigger for Autoimmune Arthritis

(2015) Rebecca Rogier et al.   Journal of Immunology Research

SLE: Another Autoimmune Disorder Influenced by Microbes and Diet?

(2015) Qinghui Mu et al.   Frontiers in Immunology

Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

(2015) Sachiko Miyake et al.   PLoS One

Dynamics of Gut Microbiota in Autoimmune Lupus

(2014) Husen Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The effects of the microbiota on the host immune system

(2014) Jacek Karczewski et al.   AUTOIMMUNITY

Gut Microbiome and Multiple Sclerosis

(2014) Pavan Bhargava et al.   Current Neurology and Neuroscience Reports

Compromised Gut Microbiota Networks in Children With Anti-Islet Cell Autoimmunity

(2014) David Endesfelder et al.   DIABETES

Aberrant gut microbiota composition at the onset of type 1 diabetes in young children

(2014) Marcus C. de Goffau et al.   DIABETOLOGIA

Probiotic Lactobacillus rhamnosus Inhibits the Formation of Neutrophil Extracellular Traps

(2014) L. Vong et al.   JOURNAL OF IMMUNOLOGY

Atlas of Multiple Sclerosis 2013: A growing global problem with widespread inequity

(2014) P. Browne et al.   NEUROLOGY

Partial depletion of natural gut flora by antibiotic aggravates collagen induced arthritis (CIA) in mice

(2014) Iwona Dorożyńska et al.   Pharmacological Reports

The Intestinal Archaea Methanosphaera stadtmanae and Methanobrevibacter smithii Activate Human Dendritic Cells

(2014) Corinna Bang et al.   PLoS One

Intestinal Dysbiosis Associated with Systemic Lupus Erythematosus

(2014) A. Hevia et al.   mBio

The Impact of Diet and Lifestyle on Gut Microbiota and Human Health

(2014) Michael Conlon et al.   Nutrients

Fecal microbiota imbalance in Mexican children with type 1 diabetes

(2014) María Esther Mejía-León et al.   Scientific Reports

Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes

(2014) Austin G. Davis-Richardson et al.   Frontiers in Microbiology

Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response

(2013) Ho-Keun Kwon et al.   CLINICAL IMMUNOLOGY

Human Intestinal Microbiota and Type 1 Diabetes

(2013) Outi Vaarala   Current Diabetes Reports

Analysis of Fecal Lactobacillus Community Structure in Patients with Early Rheumatoid Arthritis

(2013) Xiaofei Liu et al.   CURRENT MICROBIOLOGY

Microbiome and mucosal inflammation as extra-articular triggers for rheumatoid arthritis and autoimmunity

(2013) Samuel B. Brusca et al.   CURRENT OPINION IN RHEUMATOLOGY

Role of the Gut Microbiota in the Development and Function of Lymphoid Cells

(2013) N. Kamada et al.   JOURNAL OF IMMUNOLOGY

The role of pattern recognition receptors in intestinal inflammation

(2013) M Fukata et al.   Mucosal Immunology

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation

(2013) Nicholas Arpaia et al.   NATURE

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

(2013) Koji Atarashi et al.   NATURE

Probiotic supplementation improves inflammatory status in patients with rheumatoid arthritis

(2013) Elnaz Vaghef-Mehrabany et al.   NUTRITION

Commensal Akkermansia muciniphila Exacerbates Gut Inflammation in Salmonella Typhimurium-Infected Gnotobiotic Mice

(2013) Bhanu Priya Ganesh et al.   PLoS One

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

The Microbiome in Infectious Disease and Inflammation

(2012) Kenya Honda et al.   Annual Review of Immunology

Voices from within: gut microbes and the CNS

(2012) Paul Forsythe et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The role of the intestinal microbiota in type 1 diabetes

(2012) Naoko Hara et al.   CLINICAL IMMUNOLOGY

Fecal Microbiota Composition Differs Between Children With  -Cell Autoimmunity and Those Without

(2012) M. C. de Goffau et al.   DIABETES

Does the gut microbiota have a role in type 1 diabetes? Early evidence from humans and animal models of the disease

(2012) M. A. Atkinson et al.   DIABETOLOGIA

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

(2012) Michael H. Shaw et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of Sex and Age Driven Differences in the Gut Microbiome Characterize Arthritis-Susceptible *0401 Mice but Not Arthritis-Resistant *0402 Mice

(2012) Andres Gomez et al.   PLoS One

Homeland Security: IgA immunity at the frontiers of the body

(2012) Andrew J. Macpherson et al.   TRENDS IN IMMUNOLOGY

Dietary factors regulate cytokines in murine models of systemic lupus erythematosus

(2011) Chia-Chien Hsieh et al.   AUTOIMMUNITY REVIEWS

Role of the Commensal Microbiota in Normal and Pathogenic Host Immune Responses

(2011) Dan R. Littman et al.   Cell Host & Microbe

Effects of a germ-free environment on gut immune regulation and diabetes progression in non-obese diabetic (NOD) mice

(2011) C. Alam et al.   DIABETOLOGIA

Prominent Role for Plasmacytoid Dendritic Cells in Mucosal T Cell-Independent IgA Induction

(2011) Hiroyuki Tezuka et al.   IMMUNITY

Intestinal Bacterial Colonization Induces Mutualistic Regulatory T Cell Responses

(2011) Markus B. Geuking et al.   IMMUNITY

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Human nutrition, the gut microbiome and the immune system

(2011) Andrew L. Kau et al.   NATURE

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

The Lactic Acid Bacterium Pediococcus acidilactici Suppresses Autoimmune Encephalomyelitis by Inducing IL-10-Producing Regulatory T Cells

(2011) Kazushiro Takata et al.   PLoS One

Gut Microbiome Metagenomics Analysis Suggests a Functional Model for the Development of Autoimmunity for Type 1 Diabetes

(2011) Christopher T. Brown et al.   PLoS One

Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice

(2011) M. A. Kriegel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes

(2011) G. D. Wu et al.   SCIENCE

Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

(2011) Muriel Derrien et al.   Frontiers in Microbiology

Adaptive Immune Regulation in the Gut: T Cell–Dependent and T Cell–Independent IgA Synthesis

(2010) Sidonia Fagarasan et al.   Annual Review of Immunology

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

Toward defining the autoimmune microbiome for type 1 diabetes

(2010) Adriana Giongo et al.   ISME Journal

Central Nervous System Demyelinating Disease Protection by the Human Commensal Bacteroides fragilis Depends on Polysaccharide A Expression

(2010) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

(2010) J Ochoa-Repáraz et al.   Mucosal Immunology

Probiotics and the gut microbiota in intestinal health and disease

(2010) Mélanie G. Gareau et al.   Nature Reviews Gastroenterology & Hepatology

The role of secretory antibodies in infection immunity

(2010) Richard A. Strugnell et al.   NATURE REVIEWS MICROBIOLOGY

A Novel Probiotic Mixture Exerts a Therapeutic Effect on Experimental Autoimmune Encephalomyelitis Mediated by IL-10 Producing Regulatory T Cells

(2010) Shahram Lavasani et al.   PLoS One

Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

(2010) Y. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

(2010) J. L. Round et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns

(2010) M. G. Dominguez-Bello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Early life: gut microbiota and immune development in infancy

(2010) R. Martin et al.   Beneficial Microbes

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Culture-independent identification of gut bacteria correlated with the onset of diabetes in a rat model

(2009) Luiz FW Roesch et al.   ISME Journal

Role of Gut Commensal Microflora in the Development of Experimental Autoimmune Encephalomyelitis

(2009) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Effects ofBifidobacterium animalisadministered during lactation on allergic and autoimmune responses in rodents

(2008) J. Ezendam et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

(2008) Shahla Abdollahi-Roodsaz et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE