Development and Validation of a TNF Family-Based Signature for Predicting Prognosis, Tumor Immune Characteristics, and Immunotherapy Response in Colorectal Cancer Patients

Regulatory mechanisms of immune checkpoints PD-L1 and CTLA-4 in cancer

(2021) Hao Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Oxidative stress-driven DR5 upregulation restores TRAIL/Apo2L sensitivity induced by iron oxide nanoparticles in colorectal cancer

(2020) Yesi Shi et al.   BIOMATERIALS

Large-scale public data reuse to model immunotherapy response and resistance

(2020) Jingxin Fu et al.   Genome Medicine

Development of a prognostic index and screening of potential biomarkers based on immunogenomic landscape analysis of colorectal cancer

(2020) Kang Lin et al.   Aging-US

YIPF2 promotes chemotherapeutic agent-mediated apoptosis via enhancing TNFRSF10B recycling to plasma membrane in non-small cell lung cancer cells

(2020) Yingying Wang et al.   Cell Death & Disease

Colorectal Cancer and Probiotics: Are Bugs Really Drugs?

(2020) Purushottam Lamichhane et al.   Cancers

Natural killer cells in cancer biology and therapy

(2020) Song-Yang Wu et al.   Molecular Cancer

Customizing a Tridomain TRAIL Variant to Achieve Active Tumor Homing and Endogenous Albumin-Controlled Release of the Molecular Machine In Vivo

(2020) Ze Tao et al.   BIOMACROMOLECULES

First‐in‐human phase 1 study of MK‐1248, an anti–glucocorticoid‐induced tumor necrosis factor receptor agonist monoclonal antibody, as monotherapy or with pembrolizumab in patients with advanced solid tumors

(2020) Ravit Geva et al.   CANCER

Lower Rates of Colorectal Cancer in Patients With Inflammatory Bowel Disease Using Anti-TNF Therapy

(2020) Motasem Alkhayyat et al.   INFLAMMATORY BOWEL DISEASES

An antibody-tumor necrosis factor fusion protein that synergizes with oxaliplatin for treatment of colorectal cancer

(2020) Davor Bajic et al.   MOLECULAR CANCER THERAPEUTICS

Anxiety, Depression, and Colorectal Cancer Survival: Results from Two Prospective Cohorts

(2020) Claudia Trudel-Fitzgerald et al.   Journal of Clinical Medicine

Development and validation of a prognostic and immunotherapeutically relevant model in hepatocellular carcinoma

(2020) Yu Wang et al.   Annals of Translational Medicine

Regulatory T cells in cancer immunosuppression — implications for anticancer therapy

(2019) Yosuke Togashi et al.   Nature Reviews Clinical Oncology

Reversine induces cell cycle arrest and apoptosis via upregulation of the Fas and DR5 signaling pathways in human colorectal cancer cells

(2019) Young-Lan Park et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Pattern, Stage, and Time of Recurrent Colorectal Cancer After Curative Surgery

(2019) Salman Yousuf Guraya   Clinical Colorectal Cancer

Cannabidiol Enhances the Therapeutic Effects of TRAIL by Upregulating DR5 in Colorectal Cancer

(2019) Jung Lim Kim et al.   Cancers

Transcriptome profiling revealed multiple genes and ECM-receptor interaction pathways that may be associated with breast cancer

(2019) Yulong Bao et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function

(2019) Fanny Polesso et al.   JOURNAL OF IMMUNOLOGY

Perspectives on Treatment of Metastatic Colorectal Cancer with Immune Checkpoint Inhibitor Therapy

(2019) Michael A. Morse et al.   ONCOLOGIST

SMC1 promotes proliferation and inhibits apoptosis through the NF‑κB signaling pathway in colorectal cancer

(2019) Jin Li et al.   ONCOLOGY REPORTS

Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway

(2019) Chao Liu et al.   CELL DEATH AND DIFFERENTIATION

Is There a Role for Programmed Death Ligand-1 Testing and Immunotherapy in Colorectal Cancer With Microsatellite Instability? Part I—Colorectal Cancer: Microsatellite Instability, Testing, and Clinical Implications

(2018) Esmeralda Celia Marginean et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

RHBDD1 promotes colorectal cancer metastasis through the Wnt signaling pathway and its downstream target ZEB1

(2018) Mengmeng Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study

(2018) Franck Pagès et al.   LANCET

Beyond Cell Death: New Functions for TNF Family Cytokines in Autoimmunity and Tumor Immunotherapy

(2018) Fei Yi et al.   TRENDS IN MOLECULAR MEDICINE

Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response

(2018) Peng Jiang et al.   NATURE MEDICINE

TNFRSF10C methylation is a new epigenetic biomarker for colorectal cancer

(2018) Cong Zhou et al.   PeerJ

The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond

(2018) Catherine Dostert et al.   PHYSIOLOGICAL REVIEWS

Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival

(2017) Bernhard Mlecnik et al.   JNCI-Journal of the National Cancer Institute

The Interplay between Metabolism, PPAR Signaling Pathway, and Cancer

(2017) Daniele Fanale et al.   PPAR Research

Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival

(2017) Bernhard Mlecnik et al.   JNCI-Journal of the National Cancer Institute

A phase 1b clinical trial of the CD40-activating antibody CP-870,893 in combination with cisplatin and pemetrexed in malignant pleural mesothelioma

(2015) A. K. Nowak et al.   ANNALS OF ONCOLOGY

A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis

(2015) Ling Wu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

PI3K/AKT signaling pathway and cancer: an updated review

(2014) Miriam Martini et al.   ANNALS OF MEDICINE

β-catenin regulates NF-κB activityviaTNFRSF19 in colorectal cancer cells

(2014) Simon Schön et al.   INTERNATIONAL JOURNAL OF CANCER

Lentivirus-mediated RNA interference targeting WWTR1 in human colorectal cancer cells inhibits cell proliferation in vitro and tumor growth in vivo

(2012) Xingrong Lu   ONCOLOGY REPORTS