Comprehensive Intrametastatic Immune Quantification and Major Impact of Immunoscore on Survival

Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis

(2016) Minoru Koi et al.   GASTROENTEROLOGY

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability

(2016) Bernhard Mlecnik et al.   IMMUNITY

Impact ofKRAS,BRAF,PIK3CA,TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases

(2016) Inger Marie Løes et al.   INTERNATIONAL JOURNAL OF CANCER

Additional Support for the Introduction of Immune Cell Quantification in Colorectal Cancer Classification

(2016) Robert L. Ferris et al.   JNCI-Journal of the National Cancer Institute

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis

(2016) Bernhard Mlecnik et al.   Science Translational Medicine

Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection

(2016) Anita Sveen et al.   PLoS Genetics

Additional Support for the Introduction of Immune Cell Quantification in Colorectal Cancer Classification

(2016) Robert L. Ferris et al.   JNCI-Journal of the National Cancer Institute

Pathological responses after angiogenesis or EGFR inhibitors in metastatic colorectal cancer depend on the chemotherapy backbone

(2015) J Carrasco et al.   BRITISH JOURNAL OF CANCER

BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection

(2015) M Schirripa et al.   BRITISH JOURNAL OF CANCER

Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983

(2015) Erik Tanis et al.   EUROPEAN JOURNAL OF CANCER

VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis

(2015) Sebastian Foersch et al.   GASTROENTEROLOGY

Tumor Microenvironment and Immunotherapy: The Whole Picture Is Better Than a Glimpse

(2015) Sarah E. Church et al.   IMMUNITY

Using tumour phylogenetics to identify the roots of metastasis in humans

(2015) Kamila Naxerova et al.   Nature Reviews Clinical Oncology

Surgical management of metastatic colon cancer: A population-based analysis

(2015) Hadi Khan et al.   Journal of Geriatric Oncology

Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases

(2015) Anna S Berghoff et al.   OncoImmunology

RAS Mutations Predict Radiologic and Pathologic Response in Patients Treated with Chemotherapy Before Resection of Colorectal Liver Metastases

(2014) Yoshihiro Mise et al.   ANNALS OF SURGICAL ONCOLOGY

T cells but not NK cells are associated with a favourable outcome for resected colorectal liver metastases

(2014) Siân A Pugh et al.   BMC CANCER

Prognosis according to histochemical analysis of liver metastases removed at liver resection

(2014) S. M. Brunner et al.   BRITISH JOURNAL OF SURGERY

Tumor Regression Grading in Rectal Cancer: Is It Time to Move Forward?

(2014) Vincenzo Valentini et al.   JOURNAL OF CLINICAL ONCOLOGY

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

(2014) J. Zhang et al.   SCIENCE

Functional Network Pipeline Reveals Genetic Determinants Associated with in Situ Lymphocyte Proliferation and Survival of Cancer Patients

(2014) B. Mlecnik et al.   Science Translational Medicine

Early Recurrence After Liver Resection for Colorectal Metastases: Risk Factors, Prognosis, and Treatment. A LiverMetSurvey-Based Study of 6,025 Patients

(2013) Luca Viganò et al.   ANNALS OF SURGICAL ONCOLOGY

From the immune contexture to the Immunoscore: the role of prognostic and predictive immune markers in cancer

(2013) Helen Angell et al.   CURRENT OPINION IN IMMUNOLOGY

The Continuum of Cancer Immunosurveillance: Prognostic, Predictive, and Mechanistic Signatures

(2013) Jérôme Galon et al.   IMMUNITY

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours

(2013) Jérôme Galon et al.   JOURNAL OF PATHOLOGY

Radiofrequency ablation combined with systemic treatment versus systemic treatment alone in patients with non-resectable colorectal liver metastases: a randomized EORTC Intergroup phase II study (EORTC 40004)

(2012) T. Ruers et al.   ANNALS OF ONCOLOGY

Regulatory T Cell Infiltration Predicts Outcome Following Resection of Colorectal Cancer Liver Metastases

(2012) Steven C. Katz et al.   ANNALS OF SURGICAL ONCOLOGY

Cancer classification using the Immunoscore: a worldwide task force

(2012) Jérôme Galon et al.   Journal of Translational Medicine

The immune score as a new possible approach for the classification of cancer

(2012) Jérôme Galon et al.   Journal of Translational Medicine

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

(2011) Marie Tosolini et al.   CANCER RESEARCH

Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy

(2011) N. Halama et al.   CANCER RESEARCH

Histopathologic-Based Prognostic Factors of Colorectal Cancers Are Associated With the State of the Local Immune Reaction

(2011) Bernhard Mlecnik et al.   JOURNAL OF CLINICAL ONCOLOGY

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer

(2009) Bernhard Mlecnik et al.   GASTROENTEROLOGY

Association of Computed Tomography Morphologic Criteria With Pathologic Response and Survival in Patients Treated With Bevacizumab for Colorectal Liver Metastases

(2009) Yun Shin Chun   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Patients With Initially Unresectable Colorectal Liver Metastases: Is There a Possibility of Cure?

(2009) René Adam et al.   JOURNAL OF CLINICAL ONCOLOGY

In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer

(2009) Franck Pagès et al.   JOURNAL OF CLINICAL ONCOLOGY

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER

Pathologic Response to Preoperative Chemotherapy: A New Outcome End Point After Resection of Hepatic Colorectal Metastases

(2008) Dan G. Blazer et al.   JOURNAL OF CLINICAL ONCOLOGY