Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway

Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade

(2019) Ying Zhu et al.   GUT

The role of PD-1/PD-L1 axis and macrophage in the progression and treatment of cancer

(2019) Jiajing Cai et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

CD274, LAG3, and IDO1 expressions in tumor-infiltrating immune cells as prognostic biomarker for patients with MSI-high colon cancer

(2018) Soo Jung Lee et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Macrophages impede CD8 T cells from reaching tumor cells and limit the efficacy of anti–PD-1 treatment

(2018) Elisa Peranzoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomics and emerging biomarkers for immunotherapy of colorectal cancer

(2018) Jakob Nikolas Kather et al.   SEMINARS IN CANCER BIOLOGY

COP9 signalosome subunit CSN5, but not CSN6, is upregulated in lung adenocarcinoma and predicts poor prognosis

(2018) Dakai Xiao et al.   Journal of Thoracic Disease

Epigenetic Modification of the CCL5/CCR1/ERK Axis Enhances Glioma Targeting in Dedifferentiation-Reprogrammed BMSCs

(2017) Rui Chen et al.   Stem Cell Reports

Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome

(2016) Qianming Du et al.   BIOCHEMICAL PHARMACOLOGY

Characterisation of PD-L1-positive subsets of microsatellite-unstable colorectal cancers

(2016) Jung Ho Kim et al.   BRITISH JOURNAL OF CANCER

Deubiquitination and Stabilization of PD-L1 by CSN5

(2016) Seung-Oe Lim et al.   CANCER CELL

Programmed death ligand 1 expression in hepatocellular carcinoma: Relationship With clinical and pathological features

(2016) Julien Calderaro et al.   HEPATOLOGY

Cisplatin-induced CCL5 secretion from CAFs promotes cisplatin-resistance in ovarian cancer via regulation of the STAT3 and PI3K/Akt signaling pathways

(2016) BO ZHOU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Cancer-FOXP3 directly activated CCL5 to recruit FOXP3+Treg cells in pancreatic ductal adenocarcinoma

(2016) X Wang et al.   ONCOGENE

Targeted inhibition of the COP9 signalosome for treatment of cancer

(2016) Anita Schlierf et al.   Nature Communications

Diversity of COP9 signalosome structures and functional consequences

(2015) Dawadschargal Dubiel et al.   FEBS LETTERS

The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc

(2015) Xiao-Xin Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer

(2014) Yunbao Pan et al.   CANCER BIOLOGY & THERAPY

Macrophages associated with tumors as potential targets and therapeutic intermediates

(2014) Serguei Vinogradov et al.   Nanomedicine

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

(2013) D. M. Molina et al.   SCIENCE

Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature

(2012) Qiong-wen Zhang et al.   PLoS One

Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas

(2011) Jie Chen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers

(2011) Ruiying Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion

(2009) Yadi Wu et al.   CANCER CELL

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

CCL5 increases lung cancer migration via PI3K, Akt and NF-κB pathways

(2008) Chun-Yin Huang et al.   BIOCHEMICAL PHARMACOLOGY

CSN5 Isopeptidase Activity Links COP9 Signalosome Activation to Breast Cancer Progression

(2008) A. S. Adler et al.   CANCER RESEARCH