In silico identification of MicroRNAs targeting the key nucleator of stress granules, G3BP: Promising therapeutics for SARS-CoV-2 infection

The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein

(2021) Shan Lu et al.   Nature Communications

PI3K/AKT signaling pathway: a possible target for adjuvant therapy in COVID-19

(2021) Mohammad Rafi Khezri   Human Cell

SARS-CoV-2 nucleocapsid protein phase separates with G3BPs to disassemble stress granules and facilitate viral production

(2021) Lingling Luo et al.   Science Bulletin

SARS-CoV-2 nucleocapsid protein undergoes liquid–liquid phase separation into stress granules through its N-terminal intrinsically disordered region

(2021) Jia Wang et al.   Cell Discovery

Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

(2021) Adriana Marcelo et al.   Cell Death & Disease

SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication

(2021) Zhou-Qin Zheng et al.   Cell Discovery

The involvement of stress granules in aging and aging‐associated diseases

(2020) Xiuling Cao et al.   AGING CELL

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

(2020) Peiguo Yang et al.   CELL

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

GeneTrail 3: advanced high-throughput enrichment analysis

(2020) Nico Gerstner et al.   NUCLEIC ACIDS RESEARCH

miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology

(2020) Le Chang et al.   NUCLEIC ACIDS RESEARCH

Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling

(2020) Zena Wehbe et al.   Frontiers in Pharmacology

Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA

(2020) Hui Chen et al.   CELL RESEARCH

SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

(2020) Si Zhang et al.   Journal of Hematology & Oncology

Web-based tools for miRNA studies analysis

(2020) Fatemeh Shaker et al.   COMPUTERS IN BIOLOGY AND MEDICINE

SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs

(2020) Theodora Myrto Perdikari et al.   EMBO JOURNAL

Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid

(2020) Christiane Iserman et al.   MOLECULAR CELL

Nucleocapsid protein of SARS-CoV-2 phase separates into RNA-rich polymerase-containing condensates

(2020) Adriana Savastano et al.   Nature Communications

Identification of potential miRNA–mRNA regulatory network contributing to pathogenesis of HBV-related HCC

(2019) Weiyang Lou et al.   Journal of Translational Medicine

Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology

(2019) Peipei Zhang et al.   eLife

Stress granule: a promising target for cancer treatment

(2019) Xiaomeng Gao et al.   BRITISH JOURNAL OF PHARMACOLOGY

miRDB: an online database for prediction of functional microRNA targets

(2019) Yuhao Chen et al.   NUCLEIC ACIDS RESEARCH

Stress granules and neurodegeneration

(2019) Benjamin Wolozin et al.   NATURE REVIEWS NEUROSCIENCE

miRPathDB 2.0: a novel release of the miRNA Pathway Dictionary Database

(2019) Tim Kehl et al.   NUCLEIC ACIDS RESEARCH

The reactome pathway knowledgebase

(2019) Bijay Jassal et al.   NUCLEIC ACIDS RESEARCH

miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database

(2019) Hsi-Yuan Huang et al.   NUCLEIC ACIDS RESEARCH

Emerging Roles for Intermolecular RNA-RNA Interactions in RNP Assemblies

(2018) Briana Van Treeck et al.   CELL

The Diverse Roles of microRNAs at the Host–Virus Interface

(2018) Annie Bernier et al.   Viruses-Basel

Stress Granules and Processing Bodies in Translational Control

(2018) Pavel Ivanov et al.   Cold Spring Harbor Perspectives in Biology

Differences between acute and chronic stress granules, and how these differences may impact function in human disease

(2018) Lucas C. Reineke et al.   BIOCHEMICAL PHARMACOLOGY

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

TIA1 Mutations in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Promote Phase Separation and Alter Stress Granule Dynamics

(2017) Ian R. Mackenzie et al.   NEURON

DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA–gene interactions

(2017) Dimitra Karagkouni et al.   NUCLEIC ACIDS RESEARCH

Mechanistic insights into mammalian stress granule dynamics

(2016) Marc D. Panas et al.   JOURNAL OF CELL BIOLOGY

G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

(2016) Nancy Kedersha et al.   JOURNAL OF CELL BIOLOGY

Coming of age: ten years of next-generation sequencing technologies

(2016) Sara Goodwin et al.   NATURE REVIEWS GENETICS

Principles and Properties of Stress Granules

(2016) David S.W. Protter et al.   TRENDS IN CELL BIOLOGY

Rabies Virus Infection Induces the Formation of Stress Granules Closely Connected to the Viral Factories

(2016) Jovan Nikolic et al.   PLoS Pathogens

Tiny giants of gene regulation: experimental strategies for microRNA functional studies

(2016) Bruno R. Steinkraus et al.   Wiley Interdisciplinary Reviews-Developmental Biology

PI3K signalling in inflammation

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Antiviral Potential of ERK/MAPK and PI3K/AKT/mTOR Signaling Modulation for Middle East Respiratory Syndrome Coronavirus Infection as Identified by Temporal Kinome Analysis

(2014) Jason Kindrachuk et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Role of phosphatidylinositol 3-kinase (PI3K) and Akt1 kinase in porcine reproductive and respiratory syndrome virus (PRRSV) replication

(2014) Xiuqing Wang et al.   ARCHIVES OF VIROLOGY

Differential effects of Akt1 signaling on short- versus long-term consequences of myocardial infarction and reperfusion injury

(2014) Lining Ma et al.   LABORATORY INVESTIGATION

The AKT genes and their roles in various disorders

(2013) M. Michael Cohen   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders

(2013) Mani Ramaswami et al.   CELL

Interference with Akt Signaling Protects Against Myocardial Infarction and Death by Limiting the Consequences of Oxidative Stress

(2013) B. A. Kerr et al.   Science Signaling

Stress granules and cell signaling: more than just a passing phase?

(2013) Nancy Kedersha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Large G3BP-induced granules trigger eIF2α phosphorylation

(2012) Lucas C. Reineke et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of stress granules in virus systems

(2012) James P. White et al.   TRENDS IN MICROBIOLOGY

ViennaRNA Package 2.0

(2011) Ronny Lorenz et al.   Algorithms for Molecular Biology

Junin virus infection impairs stress-granule formation in Vero cells treated with arsenite via inhibition of eIF2  phosphorylation

(2011) F. N. Linero et al.   JOURNAL OF GENERAL VIROLOGY

Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA

(2010) L. G. Abrahamyan et al.   JOURNAL OF CELL SCIENCE

A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway

(2009) Christina Ehrhardt et al.   CELLULAR MICROBIOLOGY

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

(2008) Kyoko Arimoto et al.   NATURE CELL BIOLOGY

The Vienna RNA Websuite

(2008) A. R. Gruber et al.   NUCLEIC ACIDS RESEARCH