Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update

SARS-CoV-2 structural features may explain limited neutralizing-antibody responses

(2021) Martin F. Bachmann et al.   npj Vaccines

Therapeutic and prophylactic potential of anti-microbial peptides against coronaviruses

(2020) Hamed Memariani et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Antivirals Against Coronaviruses: Candidate Drugs for SARS-CoV-2 Treatment?

(2020) Igor de Andrade Santos et al.   Frontiers in Microbiology

A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2

(2020) Hanjun Zhao et al.   Nature Communications

Antimicrobial Peptides: Classification, Design, Application and Research Progress in Multiple Fields

(2020) Yuchen Huan et al.   Frontiers in Microbiology

Antiviral peptides as promising therapeutic drugs

(2019) Liana Costa Pereira Vilas Boas et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Smp76, a Scorpine-Like Peptide Isolated from the Venom of the Scorpion Scorpio maurus palmatus, with a Potent Antiviral Activity Against Hepatitis C Virus and Dengue Virus

(2019) Alaa M. H. El-Bitar et al.   International Journal of Peptide Research and Therapeutics

Current and Emerging Therapies for Ocular Herpes Simplex Virus Type-1 Infections

(2019) Raghuram Koganti et al.   Microorganisms

Development of Small-Molecule Inhibitors Against Zika Virus Infection

(2019) Lili Wang et al.   Frontiers in Microbiology

Scorpion Venom–Toxins that Aid in Drug Development: A Review

(2018) Arijit Ghosh et al.   International Journal of Peptide Research and Therapeutics

Challenge for One Health: Co-Circulation of Zoonotic H5N1 and H9N2 Avian Influenza Viruses in Egypt

(2018) Shin-Hee Kim   Viruses-Basel

Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1

(2018) Zhengyang Zeng et al.   Theranostics

A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles

(2018) Fangfang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type-I Interferon Response

(2018) Zhenglin Ji et al.   VIROLOGICA SINICA

Peptides as Therapeutic Agents for Dengue Virus

(2017) Miaw-Fang Chew et al.   International Journal of Medical Sciences

Antiviral activity of animal venom peptides and related compounds

(2017) Élida Cleyse Gomes da Mata et al.   JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES

Vaccine platform recombinant measles virus

(2017) Michael D. Mühlebach   VIRUS GENES

Combination Strategies to Enhance the Efficacy of Antimicrobial Peptides against Bacterial Biofilms

(2017) Lucia Grassi et al.   Frontiers in Microbiology

A Scorpion Defensin BmKDfsin4 Inhibits Hepatitis B Virus Replication in Vitro

(2016) Zhengyang Zeng et al.   Toxins

Unique diversity of the venom peptides from the scorpion Androctonus bicolor revealed by transcriptomic and proteomic analysis

(2015) Lei Zhang et al.   Journal of Proteomics

Broad-spectrum antivirals against viral fusion

(2015) Frederic Vigant et al.   NATURE REVIEWS MICROBIOLOGY

Scorpion venom components as potential candidates for drug development

(2015) Ernesto Ortiz et al.   TOXICON

Virocidal activity of Egyptian scorpion venoms against hepatitis C virus

(2015) Alaa MH El-Bitar et al.   Virology Journal

Proteomic analysis of the venom from the scorpion Mesobuthus martensii

(2014) Xiaobo Xu et al.   Journal of Proteomics

Antimicrobial peptides from scorpion venoms

(2014) Patrick L. Harrison et al.   TOXICON

Inhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1

(2013) Wei Hong et al.   ANTIVIRAL RESEARCH

Design of histidine-rich peptides with enhanced bioavailability and inhibitory activity against hepatitis C virus

(2013) Wei Hong et al.   BIOMATERIALS

Peptides as the next generation of anti-infectives

(2013) Derry K Mercer et al.   Future Medicinal Chemistry

Profiling the resting venom gland of the scorpion Tityus stigmurus through a transcriptomic survey

(2012) Diego D Almeida et al.   BMC GENOMICS

Bacterial resistance to cationic antimicrobial peptides

(2012) José Luis Anaya-López et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Mucroporin-M1 Inhibits Hepatitis B Virus Replication by Activating the Mitogen-activated Protein Kinase (MAPK) Pathway and Down-regulating HNF4αin Vitroandin Vivo

(2012) Zhenhuan Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-HIV-1 Activity of a New Scorpion Venom Peptide Derivative Kn2-7

(2012) Yaoqing Chen et al.   PLoS One

Venoms as a platform for human drugs: translating toxins into therapeutics

(2011) Glenn F King   EXPERT OPINION ON BIOLOGICAL THERAPY

Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses

(2011) Qiaoli Li et al.   PEPTIDES

Dengue virus life cycle: viral and host factors modulating infectivity

(2010) Izabela A. Rodenhuis-Zybert et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A new natural α-helical peptide from the venom of the scorpion Heterometrus petersii kills HCV

(2010) Ran Yan et al.   PEPTIDES

Subcellular targeting strategies for drug design and delivery

(2009) Lawrence Rajendran et al.   NATURE REVIEWS DRUG DISCOVERY

Recombinant scorpine: a multifunctional antimicrobial peptide with activity against different pathogens

(2008) R. Carballar-Lejarazú et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Involvement of phospholipase A2 pathway for the Indian red scorpion venom-induced augmentation of cardiopulmonary reflexes elicited by phenyldiguanide

(2008) Sadhana Kanoo et al.   NEUROSCIENCE LETTERS

Solution structure of stem-loop α of the hepatitis B virus post-transcriptional regulatory element

(2008) Martin Schwalbe et al.   NUCLEIC ACIDS RESEARCH