Development of Small-Molecule Inhibitors Against Zika Virus Infection
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Development of Small-Molecule Inhibitors Against Zika Virus Infection
Authors
Keywords
-
Journal
Frontiers in Microbiology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-12-06
DOI
10.3389/fmicb.2019.02725
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease
- (2019) Christoph Nitsche et al. ACS Medicinal Chemistry Letters
- Deciphering the potential of baicalin as an antiviral agent for Chikungunya virus infection
- (2018) Adrian Oo et al. ANTIVIRAL RESEARCH
- The molecular tweezer CLR01 inhibits Ebola and Zika virus infection
- (2018) Annika E. Röcker et al. ANTIVIRAL RESEARCH
- Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease
- (2018) Zhong Li et al. ANTIVIRAL RESEARCH
- Merimepodib, an IMPDH inhibitor, suppresses replication of Zika virus and other emerging viral pathogens
- (2018) Xiao Tong et al. ANTIVIRAL RESEARCH
- Exploring the Lead Compounds for Zika Virus NS2B-NS3 Protein: an e-Pharmacophore-Based Approach
- (2018) K. Rohini et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- The inhibitory effect of sodium baicalin on oseltamivir-resistant influenza A virus via reduction of neuraminidase activity
- (2018) Jing Jin et al. ARCHIVES OF PHARMACAL RESEARCH
- The A–Z of Zika drug discovery
- (2018) Melina Mottin et al. DRUG DISCOVERY TODAY
- Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
- (2018) Yan Li et al. STRUCTURE
- Toll-like receptor agonist R848 blocks Zika virus replication by inducing the antiviral protein viperin
- (2018) Bénédicte Vanwalscappel et al. VIROLOGY
- Acute Zika Virus Infection in an Endemic Area Shows Modest Proinflammatory Systemic Immunoactivation and Cytokine-Symptom Associations
- (2018) Jéssica Barletto de Sousa Barros et al. Frontiers in Immunology
- Development and Validation of a Phenotypic High-Content Imaging Assay for Assessing the Antiviral Activity of Small-Molecule Inhibitors Targeting Zika Virus
- (2018) Jean A. Bernatchez et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A novel antiviral inhibits Zika virus infection while increasing intracellular glutathione biosynthesis in distinct cell culture models.
- (2018) Mugdha Vasireddi et al. ANTIVIRAL RESEARCH
- Zika virus NS2B/NS3 proteinase: A new target for an old drug - Suramin a lead compound for NS2B/NS3 proteinase inhibition-
- (2018) Monika Aparecida Coronado et al. ANTIVIRAL RESEARCH
- Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors
- (2018) Wint Wint Phoo et al. ANTIVIRAL RESEARCH
- Baicalein and baicalin as Zika virus inhibitors
- (2018) Adrian Oo et al. ARCHIVES OF VIROLOGY
- Investigational drugs for the treatment of Zika virus infection: a preclinical and clinical update
- (2018) Yingshan Han et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles
- (2018) Fangfang Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Therapeutic treatment of Zika virus infection using a brain-penetrating antiviral peptide
- (2018) Joshua A. Jackman et al. NATURE MATERIALS
- Individualized versus conventional ovarian stimulation for in vitro fertilization: a multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial
- (2017) Anders Nyboe Andersen et al. FERTILITY AND STERILITY
- 25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model
- (2017) Chunfeng Li et al. IMMUNITY
- Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors
- (2017) Hong-Tao Xu et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Zika virus NS5 protein potential inhibitors: an enhanced in silico approach in drug discovery
- (2017) Pritika Ramharack et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- ZMPSTE24 defends against influenza and other pathogenic viruses
- (2017) Bishi Fu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Axl is not an indispensable factor for Zika virus infection in mice
- (2017) Zhao-Yang Wang et al. JOURNAL OF GENERAL VIROLOGY
- Replication of Zika Virus in Human Prostate Cells: A Potential Source of Sexually Transmitted Virus
- (2017) Jennifer L Spencer et al. JOURNAL OF INFECTIOUS DISEASES
- Suppression of Zika virus infection and replication in endothelial cells and astrocytes by PKA inhibitor PKI 14-22
- (2017) Fan Cheng et al. JOURNAL OF VIROLOGY
- Screening of FDA-Approved Drugs for Inhibitors of Japanese Encephalitis Virus Infection
- (2017) Shaobo Wang et al. JOURNAL OF VIROLOGY
- The Antigenic Structure of Zika Virus and Its Relation to Other Flaviviruses: Implications for Infection and Immunoprophylaxis
- (2017) Franz X. Heinz et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Structural Dynamics of Zika Virus NS2B-NS3 Protease Binding to Dipeptide Inhibitors
- (2017) Yan Li et al. STRUCTURE
- Structural Biology of the Zika Virus
- (2017) Yi Shi et al. TRENDS IN BIOCHEMICAL SCIENCES
- Inhibitors of the Histone Methyltransferases EZH2/1 Induce a Potent Antiviral State and Suppress Infection by Diverse Viral Pathogens
- (2017) Jesse H. Arbuckle et al. mBio
- A Novel Agonist of the TRIF Pathway Induces a Cellular State Refractory to Replication of Zika, Chikungunya, and Dengue Viruses
- (2017) Kara M. Pryke et al. mBio
- A human antibody against Zika virus crosslinks the E protein to prevent infection
- (2017) S. Saif Hasan et al. Nature Communications
- A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses
- (2017) Yufeng Yu et al. Nature Communications
- Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus
- (2017) Keiko Rausch et al. Cell Reports
- The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase
- (2017) David Estoppey et al. Cell Reports
- A Small-Molecule Oligosaccharyltransferase Inhibitor with Pan-flaviviral Activity
- (2017) Andreas S. Puschnik et al. Cell Reports
- Axl Mediates ZIKA Virus Entry in Human Glial Cells and Modulates Innate Immune Responses
- (2017) Laurent Meertens et al. Cell Reports
- Development of small-molecule viral inhibitors targeting various stages of the life cycle of emerging and re-emerging viruses
- (2017) Xiaohuan Wang et al. Frontiers of Medicine
- Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice
- (2017) Chunfeng Li et al. EBioMedicine
- Solution conformations of Zika NS2B-NS3pro and its inhibition by natural products from edible plants
- (2017) Amrita Roy et al. PLoS One
- Halogenated Chrysins Inhibit Dengue and Zika Virus Infectivity
- (2017) Aphinya Suroengrit et al. Scientific Reports
- Analysis of Ribonucleotide 5′-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays
- (2016) Gaofei Lu et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Inhibitory effect of flavonoids against NS2B-NS3 protease of ZIKA virus and their structure activity relationship
- (2016) Hee-jung Lim et al. BIOTECHNOLOGY LETTERS
- Literature-based discovery of new candidates for drug repurposing
- (2016) Hsih-Te Yang et al. BRIEFINGS IN BIOINFORMATICS
- Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody
- (2016) Lianpan Dai et al. Cell Host & Microbe
- Expression Analysis Highlights AXL as a Candidate Zika Virus Entry Receptor in Neural Stem Cells
- (2016) Tomasz J. Nowakowski et al. Cell Stem Cell
- Approved Antiviral Drugs over the Past 50 Years
- (2016) Erik De Clercq et al. CLINICAL MICROBIOLOGY REVIEWS
- Zika Virus
- (2016) Didier Musso et al. CLINICAL MICROBIOLOGY REVIEWS
- Nucleoside Inhibitors of Zika Virus
- (2016) Luděk Eyer et al. JOURNAL OF INFECTIOUS DISEASES
- Peptide–Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology
- (2016) Christoph Nitsche et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structural Insight into NS5 of Zika Virus Leading to the Discovery of MTase Inhibitors
- (2016) Preyesh Stephen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- An Approach for Zika Virus Inhibition Using Homology Structure of the Envelope Protein
- (2016) Sandun Fernando et al. MOLECULAR BIOTECHNOLOGY
- Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen
- (2016) Miao Xu et al. NATURE MEDICINE
- Zika Virus
- (2016) Lyle R. Petersen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor
- (2016) Jian Lei et al. SCIENCE
- Crystal structure of unlinked NS2B-NS3 protease from Zika virus
- (2016) Zhenzhen Zhang et al. SCIENCE
- The green tea molecule EGCG inhibits Zika virus entry
- (2016) Bruno M. Carneiro et al. VIROLOGY
- Structure of the NS2B-NS3 protease from Zika virus after self-cleavage
- (2016) Wint Wint Phoo et al. Nature Communications
- The Viral Polymerase Inhibitor 7-Deaza-2’-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model
- (2016) Joanna Zmurko et al. PLoS Neglected Tropical Diseases
- Working with Zika and Usutu Viruses In Vitro
- (2016) Kelli L. Barr et al. PLoS Neglected Tropical Diseases
- Zika virus and Zika fever
- (2016) Zhaoyang Wang et al. VIROLOGICA SINICA
- Product release is rate-limiting for catalytic processing by the Dengue virus protease
- (2016) A. E. Shannon et al. Scientific Reports
- Colloidal Aggregation and the in Vitro Activity of Traditional Chinese Medicines
- (2015) Da Duan et al. ACS Chemical Biology
- Flavonoids: True or promiscuous inhibitors of enzyme? The case of deoxyxylulose phosphate reductoisomerase
- (2015) Denis Tritsch et al. BIOORGANIC CHEMISTRY
- Biology of Zika Virus Infection in Human Skin Cells
- (2015) Rodolphe Hamel et al. JOURNAL OF VIROLOGY
- The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity
- (2015) Jonathan J Miner et al. NATURE MEDICINE
- Linker histone H1.2 establishes chromatin compaction and gene silencing through recognition of H3K27me3
- (2015) Jin-Man Kim et al. Scientific Reports
- Selection-Based Discovery of Druglike Macrocyclic Peptides
- (2014) Toby Passioura et al. Annual Review of Biochemistry
- TAM Receptors Support Neural Stem Cell Survival, Proliferation and Neuronal Differentiation
- (2014) Rui Ji et al. PLoS One
- Baicalin, a metabolite of baicalein with antiviral activity against dengue virus
- (2014) Ehsan Moghaddam et al. Scientific Reports
- NMR Analysis of a Novel Enzymatically Active Unlinked Dengue NS2B-NS3 Protease Complex
- (2013) Young Mee Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transcriptional regulation by Polycomb group proteins
- (2013) Luciano Di Croce et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Flavivirus Entry Receptors: An Update
- (2013) Manuel Perera-Lecoin et al. Viruses-Basel
- Flaviviruses: braking the entering
- (2013) Theodore C Pierson et al. Current Opinion in Virology
- A Novel Inhibitor of Dengue Virus Replication That Targets the Capsid Protein
- (2012) Chelsea M. Byrd et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Novel antiviral activity of baicalein against dengue virus
- (2012) Keivan Zandi et al. BMC Complementary and Alternative Medicine
- The TIM and TAM Families of Phosphatidylserine Receptors Mediate Dengue Virus Entry
- (2012) Laurent Meertens et al. Cell Host & Microbe
- Comparative lipidomics analysis of HIV-1 particles and their producer cell membrane in different cell lines
- (2012) Maier Lorizate et al. CELLULAR MICROBIOLOGY
- Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
- (2012) Bruno D. Fonseca et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2
- (2012) Sharad K. Verma et al. ACS Medicinal Chemistry Letters
- Niclosamide Is a Proton Carrier and Targets Acidic Endosomes with Broad Antiviral Effects
- (2012) Andreas Jurgeit et al. PLoS Pathogens
- (−)-Epigallocatechin-3-gallate is a new inhibitor of hepatitis C virus entry
- (2011) Noémie Calland et al. HEPATOLOGY
- Binding of Low Molecular Weight Inhibitors Promotes Large Conformational Changes in the Dengue Virus NS2B-NS3 Protease: Fold Analysis by Pseudocontact Shifts
- (2011) Laura de la Cruz et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Polycomb complex PRC2 and its mark in life
- (2011) Raphaël Margueron et al. NATURE
- New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
- (2010) Jonathan B. Baell et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mechanism of an Amphipathic α-Helical Peptide’s Antiviral Activity Involves Size-Dependent Virus Particle Lysis
- (2009) Nam-Joon Cho et al. ACS Chemical Biology
- Preclinical development of the green tea catechin, epigallocatechin gallate, as an HIV-1 therapy
- (2009) Christina L. Nance et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Epigallocatechin Gallate Inactivates Clinical Isolates of Herpes Simplex Virus
- (2008) C. E. Isaacs et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Mechanism of Thioesterase-Catalyzed Chain Release in the Biosynthesis of the Polyether Antibiotic Nanchangmycin
- (2008) Tiangang Liu et al. CHEMISTRY & BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now