SUMOylation modification-mediated cell death

SUMO pathway inhibition targets an aggressive pancreatic cancer subtype

(2020) Alexander Biederstädt et al.   GUT

The role of SUMOylation during development

(2020) Ana Talamillo et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Nrf2 inhibits ferroptosis and protects against acute lung injury due to intestinal ischemia reperfusion via regulating SLC7A11 and HO-1

(2020) Hui Dong et al.   Aging-US

Ferroptosis in Liver Diseases: An Overview

(2020) Martina Maria Capelletti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Senescence-Centric View of Aging: Implications for Longevity and Disease

(2020) M. Borghesan et al.   TRENDS IN CELL BIOLOGY

Autophagy as a modulator of cell death machinery

(2020) Masayuki Noguchi et al.   Cell Death & Disease

PDPK1 regulates autophagosome biogenesis by binding to PIK3C3

(2020) Boli Hu et al.   Autophagy

SENP7 knockdown inhibited pyroptosis and NF-κB/NLRP3 inflammasome pathway activation in Raw 264.7 cells

(2020) Xun Li et al.   Scientific Reports

NRF2 regulates the sensitivity of human NSCLC cells to cystine deprivation-induced ferroptosis via FOCAD-FAK signaling pathway

(2020) Pengfei Liu et al.   Redox Biology

The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells

(2020) Zili Zhang et al.   Redox Biology

Oxidative Damage and Antioxidant Defense in Ferroptosis

(2020) Feimei Kuang et al.   Frontiers in Cell and Developmental Biology

Tumor Cell Escape from Therapy-Induced Senescence as a Model of Disease Recurrence after Dormancy

(2019) Tareq Saleh et al.   CANCER RESEARCH

Hemin-induced platelet activation and ferroptosis is mediated through ROS-driven proteasomal activity and inflammasome activation: Protection by Melatonin

(2019) Somanathapura K. NaveenKumar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The role of protein SUMOylation in rheumatoid arthritis

(2019) Sajad Dehnavi et al.   JOURNAL OF AUTOIMMUNITY

SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling pathways

(2019) Yanfang Yang et al.   Cell Communication and Signaling

MS-based strategies for identification of protein SUMOylation modification

(2019) Zenghua Sheng et al.   ELECTROPHORESIS

Intercellular interaction dictates cancer cell ferroptosis via NF2–YAP signalling

(2019) Jiao Wu et al.   NATURE

A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3

(2019) Kejia Liu et al.   Autophagy

NRF2 SUMOylation promotes de novo serine synthesis and maintains HCC tumorigenesis

(2019) Haoyan Guo et al.   CANCER LETTERS

Silencing SUMO2 promotes protection against degradation and apoptosis of nucleus pulposus cells through p53 signaling pathway in intervertebral disc degeneration

(2018) Liu-Zhong Jin et al.   BIOSCIENCE REPORTS

SUMO-specific proteases and isopeptidases of the SENP family at a glance

(2018) Kathrin Kunz et al.   JOURNAL OF CELL SCIENCE

Small-Molecule Inhibitors Targeting Protein SUMOylation as Novel Anticancer Compounds

(2018) Yanfang Yang et al.   MOLECULAR PHARMACOLOGY

BECN1 is a new driver of ferroptosis

(2018) Rui Kang et al.   Autophagy

Control of SUMO and Ubiquitin by ROS: Signaling and disease implications

(2018) Nicolas Stankovic-Valentin et al.   MOLECULAR ASPECTS OF MEDICINE

SUMO-mediated regulation of NLRP3 modulates inflammasome activity

(2018) Rachael Barry et al.   Nature Communications

Glutathione peroxidase 4-catalyzed reduction of lipid hydroperoxides in membranes: The polar head of membrane phospholipids binds the enzyme and addresses the fatty acid hydroperoxide group toward the redox center

(2017) Giorgio Cozza et al.   FREE RADICAL BIOLOGY AND MEDICINE

Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor

(2017) Xingyue He et al.   Nature Chemical Biology

Protein SUMOylation modification and its associations with disease

(2017) Yanfang Yang et al.   Open Biology

Autophagy regulates UBC9 levels during viral-mediated tumorigenesis

(2017) Domenico Mattoscio et al.   PLoS Pathogens

UBC9-Mediated Sumoylation Favorably Impacts Cardiac Function in Compromised HeartsNovelty and Significance

(2016) Manish K. Gupta et al.   CIRCULATION RESEARCH

The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease

(2016) K. Atkins et al.   CLINICAL SCIENCE

SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy

(2015) Eun Young Kim et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

MAPL SUMOylation of Drp1 Stabilizes an ER/Mitochondrial Platform Required for Cell Death

(2015) Julien Prudent et al.   MOLECULAR CELL

PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence

(2015) Lisa Ivanschitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure

(2015) Changwon Kho et al.   Nature Communications

SUMO1 promotes Aβ production via the modulation of autophagy

(2014) Sun-Jung Cho et al.   Autophagy

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Disruption of SUMO-Specific Protease 2 Induces Mitochondria Mediated Neurodegeneration

(2014) Jiang Fu et al.   PLoS Genetics

SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia

(2013) Chun Guo et al.   EMBO JOURNAL

PML, SUMOylation, and Senescence

(2013) Lisa Ivanschitz et al.   Frontiers in Oncology

Defective sumoylation pathway directs congenital heart disease

(2011) Jun Wang et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

SUMO2/3 Conjugation is an Endogenous Neuroprotective Mechanism

(2011) Anna Lena Datwyler et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate

(2009) Isao Fukuda et al.   CHEMISTRY & BIOLOGY

SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle

(2009) Claudia Figueroa-Romero et al.   FASEB JOURNAL

Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts

(2008) Kristin E. Yates et al.   AGING CELL