Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche

Intestinal epithelial regeneration: active versus reserve stem cells and plasticity mechanisms

(2020) Soham Karmakar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Tumor Microenvironment

(2020) Borros Arneth   Medicina-Lithuania

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

(2020) Mirjana Efremova et al.   Nature Protocols

Bidirectional Crosstalk Between Cancer Stem Cells and Immune Cell Subsets

(2020) Luise Müller et al.   Frontiers in Immunology

The future of cancer immunotherapy: microenvironment-targeting combinations

(2020) Yonina R. Murciano-Goroff et al.   CELL RESEARCH

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer

(2020) Arianna Fumagalli et al.   Cell Stem Cell

Overcoming Wnt–β-catenin dependent anticancer therapy resistance in leukaemia stem cells

(2020) John M. Perry et al.   NATURE CELL BIOLOGY

Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front

(2020) Christian M. Schürch et al.   CELL

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

(2020) Priscilla Cheung et al.   Cell Stem Cell

Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells

(2019) Yuxuan Miao et al.   CELL

Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell

(2019) Arshad Ayyaz et al.   NATURE

CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors

(2019) Andrea Walens et al.   eLife

Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

(2019) Rene Jackstadt et al.   CANCER CELL

Decoding human fetal liver haematopoiesis

(2019) Dorin-Mirel Popescu et al.   NATURE

LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer

(2018) Masoud F. Tavazoie et al.   CELL

Promotion of Tumor Growth by ADAMTS4 in Colorectal Cancer: Focused on Macrophages

(2018) Jianjun Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Role of Macrophages in Brain Tumor Growth and Progression

(2018) Elia Guadagno et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia

(2018) Kara L McKinley et al.   eLife

Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma

(2018) Carlos R. Figueiredo et al.   Frontiers in Immunology

Targeting Macrophages in Cancer: From Bench to Bedside

(2018) Ashleigh R. Poh et al.   Frontiers in Oncology

Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain

(2018) Arpiar Saunders et al.   CELL

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Reserve Stem Cells in Intestinal Homeostasis and Injury

(2018) Eric D. Bankaitis et al.   GASTROENTEROLOGY

An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion

(2018) John D. Klement et al.   JOURNAL OF CLINICAL INVESTIGATION

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C − Cells

(2017) Alexander Mildner et al.   IMMUNITY

Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells

(2017) Hsi-Hsien Hsu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Ribosomal Protein S19 Suppresses Antitumor Immune Responses via the Complement C5a Receptor 1

(2017) Maciej M. Markiewski et al.   JOURNAL OF IMMUNOLOGY

Macrophages induce EMT to promote invasion of lung cancer cells through the IL-6-mediated COX-2/PGE 2 /β-catenin signalling pathway

(2017) Dehai Che et al.   MOLECULAR IMMUNOLOGY

Prostaglandin E2–EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms

(2017) Tomohiro Aoki et al.   Science Signaling

Hierarchy and Plasticity in the Intestinal Stem Cell Compartment

(2017) Maryam Yousefi et al.   TRENDS IN CELL BIOLOGY

Prostaglandin E2–EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms

(2017) Tomohiro Aoki et al.   Science Signaling

Characteristics and Significance of the Pre-metastatic Niche

(2016) Yang Liu et al.   CANCER CELL

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium

(2016) Hiroyuki Miyoshi et al.   EMBO JOURNAL

Tumor-associated macrophages induce vasculogenic mimicry of glioblastoma multiforme through cyclooxygenase-2 activation

(2016) Xiaoming Rong et al.   Oncotarget

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

(2015) Santiago Zelenay et al.   CELL

Krt19+/Lgr5− Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine

(2015) Samuel Asfaha et al.   Cell Stem Cell

Mouse models of intestinal cancer

(2015) Rene Jackstadt et al.   JOURNAL OF PATHOLOGY

CCL2 Promotes Colorectal Carcinogenesis by Enhancing Polymorphonuclear Myeloid-Derived Suppressor Cell Population and Function

(2015) Eunyoung Chun et al.   Cell Reports

Evolution of the Cancer Stem Cell Model

(2014) Antonija Kreso et al.   Cell Stem Cell

T-Cell and NK-Cell Infiltration into Solid Tumors: A Key Limiting Factor for Efficacious Cancer Immunotherapy

(2014) I. Melero et al.   Cancer Discovery

Disruption of Fas-Fas Ligand Signaling, Apoptosis, and Innate Immunity by Bacterial Pathogens

(2014) Adam J. Caulfield et al.   PLoS Pathogens

Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy

(2013) S. Mok et al.   CANCER RESEARCH

Isolation and Characterization of Intestinal Stem Cells Based on Surface Marker Combinations and Colony-Formation Assay

(2013) Fengchao Wang et al.   GASTROENTEROLOGY

The Immunobiology of Prostanoid Receptor Signaling in Connecting Innate and Adaptive Immunity

(2013) Hedi Harizi   Biomed Research International

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Cancer Stem Cell Niche: The Place to Be

(2011) T. Borovski et al.   CANCER RESEARCH

Cooperation between both Wnt/ -catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion

(2011) J. M. Perry et al.   GENES & DEVELOPMENT

Coexistence of Quiescent and Active Adult Stem Cells in Mammals

(2010) L. Li et al.   SCIENCE

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

Fishing for a WNT-PGE2 Link: β-Catenin Is Caught in the Stem Cell Net-work

(2009) Todd Evans   Cell Stem Cell

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Stem cell concepts renew cancer research

(2008) J. E. Dick   BLOOD

IGF-1 receptor-mediated ERK/MAPK signaling couples status epilepticus to progenitor cell proliferation in the subgranular layer of the dentate gyrus

(2008) Yun-Sik Choi et al.   GLIA