An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion
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Title
An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 128, Issue 12, Pages 5549-5560
Publisher
American Society for Clinical Investigation
Online
2018-11-05
DOI
10.1172/jci123360
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- (2018) Rajendra Karki et al. CELL
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- (2018) Charlotte E. Ariyan et al. Cancer Immunology Research
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- (2017) Janna Krueger et al. IMMUNITY
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- (2017) Colleen S. Netherby et al. JOURNAL OF IMMUNOLOGY
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- (2017) Laetitia Marisa et al. JNCI-Journal of the National Cancer Institute
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- (2017) Enfu Hui et al. SCIENCE
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- (2017) Alice O. Kamphorst et al. SCIENCE
- IRF8-dependent molecular complexes control the Th9 transcriptional program
- (2017) Etienne Humblin et al. Nature Communications
- The Balance Between Cytotoxic T-cell Lymphocytes and Immune Checkpoint Expression in the Prognosis of Colon Tumors
- (2017) Laetitia Marisa et al. JNCI-Journal of the National Cancer Institute
- IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively
- (2016) Dorine Sichien et al. IMMUNITY
- IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis
- (2016) Katarzyna M. Luda et al. IMMUNITY
- Glycogen Synthase Kinase 3 Inactivation Drives T-bet-Mediated Downregulation of Co-receptor PD-1 to Enhance CD8+ Cytolytic T Cell Responses
- (2016) Alison Taylor et al. IMMUNITY
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- (2016) Dane M Newman et al. IMMUNOLOGY AND CELL BIOLOGY
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- (2016) Emily M. Mace et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2016) Ming Yan et al. JOURNAL OF IMMUNOLOGY
- Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway
- (2016) Vassiliki A. Boussiotis NEW ENGLAND JOURNAL OF MEDICINE
- Interferon Regulator Factor 8 (IRF8) Limits Ocular Pathology during HSV-1 Infection by Restraining the Activation and Expansion of CD8+ T Cells
- (2016) Lin Sun et al. PLoS One
- PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations
- (2016) Weiping Zou et al. Science Translational Medicine
- Positive predictive value of breast lesions of uncertain malignant potential (B3): Can we identify high risk patients? The value of a multidisciplinary team and implications in the surgical treatment
- (2016) Taffurelli M et al. SURGICAL ONCOLOGY-OXFORD
- The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells
- (2016) Chunwan Lu et al. OncoImmunology
- Transcription factor IRF8 controls Th1-like regulatory T-cell function
- (2015) Wonyong Lee et al. Cellular & Molecular Immunology
- TCR and CD28 activate the transcription factor NF-κB in T-cells via distinct adaptor signaling complexes
- (2015) Youg Raj Thaker et al. IMMUNOLOGY LETTERS
- Dual Function of the IRF8 Transcription Factor in Autoimmune Uveitis: Loss of IRF8 in T Cells Exacerbates Uveitis, WhereasIrf8Deletion in the Retina Confers Protection
- (2015) Sung-Hye Kim et al. JOURNAL OF IMMUNOLOGY
- Batf3 maintains autoactivation of Irf8 for commitment of a CD8α+ conventional DC clonogenic progenitor
- (2015) Gary E Grajales-Reyes et al. NATURE IMMUNOLOGY
- CD8 T-cell recognition of acquired alloantigen promotes acute allograft rejection
- (2015) Simon J. F. Harper et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adaptive Immune Resistance: How Cancer Protects from Immune Attack
- (2015) A. Ribas Cancer Discovery
- Combinatorial Immunotherapy of Polyinosinic–Polycytidylic Acid and Blockade of Programmed Death-Ligand 1 Induce Effective CD8 T-cell Responses against Established Tumors
- (2014) Toshihiro Nagato et al. CLINICAL CANCER RESEARCH
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- (2014) Yuko Yoshida et al. IMMUNITY
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- (2014) F. Miyagawa et al. JOURNAL OF IMMUNOLOGY
- A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation
- (2014) Hongsheng Wang et al. JOURNAL OF IMMUNOLOGY
- IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils
- (2014) Daisuke Kurotaki et al. Nature Communications
- Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation
- (2013) D. Kurotaki et al. BLOOD
- IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors
- (2012) A. M. Becker et al. BLOOD
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 T cells
- (2012) Fumi Miyagawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NFATc3 regulates the transcription of genes involved in T-cell activation and angiogenesis
- (2011) K. Urso et al. BLOOD
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- (2011) Charlly Kao et al. NATURE IMMUNOLOGY
- T cell exhaustion
- (2011) E John Wherry NATURE IMMUNOLOGY
- IRF8Mutations and Human Dendritic-Cell Immunodeficiency
- (2011) Sophie Hambleton et al. NEW ENGLAND JOURNAL OF MEDICINE
- Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation
- (2011) Xinshou Ouyang et al. Nature Communications
- Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease
- (2010) F. Zhao et al. BLOOD
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- (2010) Bas J.G. Baaten et al. IMMUNITY
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- (2010) J. Feng et al. JOURNAL OF IMMUNOLOGY
- PD-1 and Its Ligands in Tolerance and Immunity
- (2008) Mary E. Keir et al. Annual Review of Immunology
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