A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism

Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges

(2019) Hernandez Moura Silva et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

(2019) Apostolos Polykratis et al.   NATURE CELL BIOLOGY

Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

(2019) Johnny Bonnardel et al.   IMMUNITY

A20 at the Crossroads of Cell Death, Inflammation, and Autoimmunity

(2019) Arne Martens et al.   Cold Spring Harbor Perspectives in Biology

Adipose tissue macrophages and their polarization in health and obesity

(2018) Leen Catrysse et al.   CELLULAR IMMUNOLOGY

Irg1expression in myeloid cells prevents immunopathology duringM. tuberculosisinfection

(2018) Sharmila Nair et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

(2018) David A. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update on glycerol-3-phosphate acyltransferases: the roles in the development of insulin resistance

(2018) Jing Yu et al.   Nutrition & Diabetes

Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin

(2018) Yuji Ogawa et al.   Scientific Reports

Adapting to obesity with adipose tissue inflammation

(2017) Shannon M. Reilly et al.   Nature Reviews Endocrinology

Inflammation and the Metabolic Syndrome: The Tissue-Specific Functions of NF-κB

(2017) Leen Catrysse et al.   TRENDS IN CELL BIOLOGY

A20 inhibition of STAT1 expression in myeloid cells: a novel endogenous regulatory mechanism preventing development of enthesitis

(2016) Katelijne De Wilde et al.   ANNALS OF THE RHEUMATIC DISEASES

Thermoneutral Housing Accelerates Metabolic Inflammation to Potentiate Atherosclerosis but Not Insulin Resistance

(2016) Xiao Yu Tian et al.   Cell Metabolism

Trapping mammalian protein complexes in viral particles

(2016) Sven Eyckerman et al.   Nature Communications

Immune Regulation of Metabolic Homeostasis in Health and Disease

(2015) Jonathan R. Brestoff et al.   CELL

Mice deleted for GPAT3 have reduced GPAT activity in white adipose tissue and altered energy and cholesterol homeostasis in diet-induced obesity

(2014) Jingsong Cao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor

(2014) Chongben Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

(2014) David O’Sullivan et al.   IMMUNITY

Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

(2014) Lieselotte Vande Walle et al.   NATURE

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation

(2013) Xiaoyuan Xu et al.   Cell Metabolism

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis

(2013) J. I. Odegaard et al.   SCIENCE

A20 in inflammation and autoimmunity

(2013) Leen Catrysse et al.   TRENDS IN IMMUNOLOGY

Implication of inflammatory signaling pathways in obesity-induced insulin resistance

(2013) Jean-François Tanti et al.   Frontiers in Endocrinology

Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway

(2012) Monika Julia Wolf et al.   CANCER CELL

The cellular and signaling networks linking the immune system and metabolism in disease

(2012) Olivia Osborn et al.   NATURE MEDICINE

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Genetic relationships betweenA20/TNFAIP3, chronic inflammation and autoimmune disease

(2011) Lars Vereecke et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Inflammatory links between obesity and metabolic disease

(2011) Carey N. Lumeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Itaconic Acid Is a Mammalian Metabolite Induced during Macrophage Activation

(2011) Cheryl L. Strelko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

(2011) Mourad Matmati et al.   NATURE GENETICS

A guide to analysis of mouse energy metabolism

(2011) Matthias H Tschöp et al.   NATURE METHODS

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

(2010) Lars Vereecke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Toll-like receptors: linking inflammation to metabolism

(2010) A. Christine Könner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The Proinflammatory Cytokine-Induced IRG1 Protein Associates with Mitochondria

(2008) Daniel Degrandi et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH