Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment
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Title
Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment
Authors
Keywords
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Journal
Alzheimers Research & Therapy
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-10
DOI
10.1186/s13195-021-00850-3
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Note: Only part of the references are listed.- The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning
- (2021) Gabriel A. Erausquin et al. Alzheimers & Dementia
- Inflammatory leptomeningeal cytokines mediate COVID-19 neurologic symptoms in cancer patients
- (2021) Jan Remsik et al. CANCER CELL
- ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response
- (2021) Cheng Wang et al. Cell Stem Cell
- Neuroinvasion of SARS-CoV-2 in human and mouse brain
- (2021) Eric Song et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Molecular characterization of selectively vulnerable neurons in Alzheimer’s disease
- (2021) Kun Leng et al. NATURE NEUROSCIENCE
- AlzGPS: a genome-wide positioning systems platform to catalyze multi-omics for Alzheimer’s drug discovery
- (2021) Yadi Zhou et al. Alzheimers Research & Therapy
- COVID‐19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US
- (2021) QuanQiu Wang et al. Alzheimers & Dementia
- Frequency and profile of objective cognitive deficits in hospitalized patients recovering from COVID-19
- (2021) Abhishek Jaywant et al. NEUROPSYCHOPHARMACOLOGY
- The Epidemiological and Mechanistic Understanding of the Neurological Manifestations of COVID-19: A Comprehensive Meta-Analysis and a Network Medicine Observation
- (2021) Jiayu Shen et al. Frontiers in Neuroscience
- High-dimensional characterization of post-acute sequelae of COVID-19
- (2021) Ziyad Al-Aly et al. NATURE
- The neuroinvasive potential of SARS‐CoV2 may be at least partially responsible for the respiratory failure of COVID‐19 patients
- (2020) Yan‐Chao Li et al. JOURNAL OF MEDICAL VIROLOGY
- SciPy 1.0: fundamental algorithms for scientific computing in Python
- (2020) Pauli Virtanen et al. NATURE METHODS
- Is the Collapse of the Respiratory Center in the Brain Responsible for Respiratory Breakdown in COVID-19 Patients?
- (2020) Sonu Gandhi et al. ACS Chemical Neuroscience
- A potential role for integrins in host cell entry by SARS-CoV-2
- (2020) Christian JA Sigrist et al. ANTIVIRAL RESEARCH
- Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
- (2020) Daniel Blanco-Melo et al. CELL
- SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
- (2020) Carly G.K. Ziegler et al. CELL
- Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China
- (2020) Chuan Qin et al. CLINICAL INFECTIOUS DISEASES
- SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells
- (2020) Soeren Lukassen et al. EMBO JOURNAL
- Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process
- (2020) Hao Zhang et al. GUT
- JAK Inhibition as a New Treatment Strategy for Patients with COVID-19
- (2020) Farhad Seif et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs
- (2020) Abhigyan Choudhury et al. JOURNAL OF MEDICAL VIROLOGY
- Clinical Presentation of COVID19 in Dementia Patients
- (2020) Angelo Bianchetti et al. Journal of Nutrition Health & Aging
- Proteomics of SARS-CoV-2-infected host cells reveals therapy targets
- (2020) Denisa Bojkova et al. NATURE
- A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
- (2020) David E. Gordon et al. NATURE
- SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
- (2020) Waradon Sungnak et al. NATURE MEDICINE
- Neurologic manifestations in hospitalized patients with COVID-19: The ALBACOVID registry
- (2020) Carlos Manuel Romero-Sánchez et al. NEUROLOGY
- Neurologic Features in Severe SARS-CoV-2 Infection
- (2020) Julie Helms et al. NEW ENGLAND JOURNAL OF MEDICINE
- Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019
- (2020) Adeel S. Zubair et al. JAMA Neurology
- Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China
- (2020) Ling Mao et al. JAMA Neurology
- The Spectrum of Neurologic Disease in the Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic Infection
- (2020) Samuel J. Pleasure et al. JAMA Neurology
- Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
- (2020) Yadi Zhou et al. Cell Discovery
- Distribution of ACE2, CD147, CD26 and other SARS‐CoV‐2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID‐19 risk factors
- (2020) U. Radzikowska et al. ALLERGY
- Elevated Expression of Serum Endothelial Cell Adhesion Molecules in COVID-19 Patients
- (2020) Ming Tong et al. JOURNAL OF INFECTIOUS DISEASES
- LY6E Restricts the Entry of Human Coronaviruses, Including the Currently Pandemic SARS-CoV-2
- (2020) Xuesen Zhao et al. JOURNAL OF VIROLOGY
- Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort
- (2020) Janice L Atkins et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Harnessing endophenotypes and network medicine for Alzheimer's drug repurposing
- (2020) Jiansong Fang et al. MEDICINAL RESEARCH REVIEWS
- The COVID-19 Pandemic: Consideration for Brain Infection
- (2020) Xiao-Yuan Mao et al. NEUROSCIENCE
- Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
- (2020) Jérôme Hadjadj et al. SCIENCE
- Interferon-Induced Transmembrane Protein (IFITM3) Is Upregulated Explicitly in SARS-CoV-2 Infected Lung Epithelial Cells
- (2020) Mahmood Yaseen Hachim et al. Frontiers in Immunology
- LY6E impairs coronavirus fusion and confers immune control of viral disease
- (2020) Stephanie Pfaender et al. Nature Microbiology
- Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
- (2020) Jeong Seok Lee et al. Science Immunology
- Identification of required host factors for SARS-CoV-2 infection in human cells
- (2020) Zharko Daniloski et al. CELL
- Effects of COVID-19 on the Nervous System
- (2020) Costantino Iadecola et al. CELL
- Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection
- (2020) Jin Wei et al. CELL
- The landscape of cognitive function in recovered COVID-19 patients
- (2020) Hetong Zhou et al. JOURNAL OF PSYCHIATRIC RESEARCH
- The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease
- (2020) Ji-Yeun Hur et al. NATURE
- Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer’s disease
- (2020) Shun-Fat Lau et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
- (2020) David E. Gordon et al. SCIENCE
- Neuropilin-1 is a host factor for SARS-CoV-2 infection
- (2020) James L. Daly et al. SCIENCE
- Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity
- (2020) Ludovico Cantuti-Castelvetri et al. SCIENCE
- Is COVID-19 a Perfect Storm for Parkinson’s Disease?
- (2020) Patrik Brundin et al. TRENDS IN NEUROSCIENCES
- Large-Scale Multi-omic Analysis of COVID-19 Severity
- (2020) Katherine A. Overmyer et al. Cell Systems
- Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses
- (2020) Ruofan Wang et al. CELL
- Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid
- (2020) Michael Heming et al. IMMUNITY
- Pattern of cognitive deficits in severe COVID-19
- (2020) Valérie Beaud et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19
- (2020) Jenny Meinhardt et al. NATURE NEUROSCIENCE
- The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice
- (2020) Elizabeth M. Rhea et al. NATURE NEUROSCIENCE
- The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier
- (2020) Tetyana P. Buzhdygan et al. NEUROBIOLOGY OF DISEASE
- Microvascular Injury in the Brains of Patients with Covid-19
- (2020) Myoung-Hwa Lee et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cognitive impact of COVID-19: looking beyond the short term
- (2020) Scott Miners et al. Alzheimers Research & Therapy
- Neurologic manifestations associated with COVID-19: a multicentre registry
- (2020) Elodie Meppiel et al. CLINICAL MICROBIOLOGY AND INFECTION
- Network-based prediction of drug combinations
- (2019) Feixiong Cheng et al. Nature Communications
- Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer
- (2019) Iris Nira Smith et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1
- (2019) Hanadie Yousef et al. NATURE MEDICINE
- A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data
- (2019) Quan Wang et al. NATURE NEUROSCIENCE
- Hypothesis: cerebrospinal fluid protein markers suggest a pathway toward symptomatic resilience to AD pathology
- (2019) Pierre-François Meyer et al. Alzheimers & Dementia
- A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation
- (2019) Alexandra Grubman et al. NATURE NEUROSCIENCE
- A genome-wide positioning systems network algorithm for in silico drug repurposing
- (2019) Feixiong Cheng et al. Nature Communications
- Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs
- (2019) A. B. Niculescu et al. MOLECULAR PSYCHIATRY
- Disease Ontology: improving and unifying disease annotations across species
- (2018) Susan M. Bello et al. Disease Models & Mechanisms
- Integrating single-cell transcriptomic data across different conditions, technologies, and species
- (2018) Andrew Butler et al. NATURE BIOTECHNOLOGY
- Network-based approach to prediction and population-based validation of in silico drug repurposing
- (2018) Feixiong Cheng et al. Nature Communications
- Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer’s disease
- (2018) Frederic Brosseron et al. Alzheimers Research & Therapy
- The BioGRID interaction database: 2019 update
- (2018) Rose Oughtred et al. NUCLEIC ACIDS RESEARCH
- On the Dependency of Cellular Protein Levels on mRNA Abundance
- (2016) Yansheng Liu et al. CELL
- Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
- (2016) Maxim V. Kuleshov et al. NUCLEIC ACIDS RESEARCH
- The BioPlex Network: A Systematic Exploration of the Human Interactome
- (2015) Edward L. Huttlin et al. CELL
- Uncovering disease-disease relationships through the incomplete interactome
- (2015) J. Menche et al. SCIENCE
- Clinical significance of circulating vascular cell adhesion molecule-1 to white matter disintegrity in Alzheimer’s dementia
- (2015) Chi-Wei Huang et al. THROMBOSIS AND HAEMOSTASIS
- Protection of TGF-β1 against Neuroinflammation and Neurodegeneration in Aβ1–42-Induced Alzheimer’s Disease Model Rats
- (2015) Jia-Hui Chen et al. PLoS One
- Quantitative network mapping of the human kinome interactome reveals new clues for rational kinase inhibitor discovery and individualized cancer therapy
- (2015) Feixiong Cheng et al. Oncotarget
- A Proteome-Scale Map of the Human Interactome Network
- (2014) Thomas Rolland et al. CELL
- PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
- (2014) Peter V. Hornbeck et al. NUCLEIC ACIDS RESEARCH
- PhosphoNetworks: a database for human phosphorylation networks
- (2013) J. Hu et al. BIOINFORMATICS
- INstruct: a database of high-quality 3D structurally resolved protein interactome networks
- (2013) Michael J. Meyer et al. BIOINFORMATICS
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- The MIntAct project—IntAct as a common curation platform for 11 molecular interaction databases
- (2013) Sandra Orchard et al. NUCLEIC ACIDS RESEARCH
- dbPTM 3.0: an informative resource for investigating substrate site specificity and functional association of protein post-translational modifications
- (2012) Cheng-Tsung Lu et al. NUCLEIC ACIDS RESEARCH
- InnateDB: systems biology of innate immunity and beyond—recent updates and continuing curation
- (2012) Karin Breuer et al. NUCLEIC ACIDS RESEARCH
- Circadian Clock Gene Expression in Brain Regions of Alzheimer ’s Disease Patients and Control Subjects
- (2011) Nicolas Cermakian et al. JOURNAL OF BIOLOGICAL RHYTHMS
- PINA v2.0: mining interactome modules
- (2011) Mark J. Cowley et al. NUCLEIC ACIDS RESEARCH
- MINT, the molecular interaction database: 2012 update
- (2011) Luana Licata et al. NUCLEIC ACIDS RESEARCH
- Vascular Cell Adhesion Molecule-1 Expression and Signaling During Disease: Regulation by Reactive Oxygen Species and Antioxidants
- (2010) Joan M. Cook-Mills et al. ANTIOXIDANTS & REDOX SIGNALING
- Clinical Aspects of Melatonin Intervention in Alzheimers Disease Progression
- (2010) Daniel P. Cardinali et al. Current Neuropharmacology
- β-Arrestin 2 regulates toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3β
- (2010) Hui Li et al. IMMUNOLOGY
- Phospho.ELM: a database of phosphorylation sites--update 2011
- (2010) H. Dinkel et al. NUCLEIC ACIDS RESEARCH
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Markers of endothelial dysfunction in older subjects with late onset Alzheimer's disease or vascular dementia
- (2008) G. Zuliani et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Human Protein Reference Database--2009 update
- (2008) T. S. Keshava Prasad et al. NUCLEIC ACIDS RESEARCH
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