TrendyGenes, a computational pipeline for the detection of literature trends in academia and drug discovery
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
TrendyGenes, a computational pipeline for the detection of literature trends in academia and drug discovery
Authors
Keywords
-
Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-08-03
DOI
10.1038/s41598-021-94897-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Moving targets in drug discovery
- (2020) Barbara Zdrazil et al. Scientific Reports
- Ontology based text mining of gene-phenotype associations: application to candidate gene prediction
- (2019) Şenay Kafkas et al. Database-The Journal of Biological Databases and Curation
- Death by inflammation: drug makers chase the master controller
- (2019) Cormac Sheridan NATURE BIOTECHNOLOGY
- Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS
- (2019) Matthieu Gratia et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Exploiting machine learning for end-to-end drug discovery and development
- (2019) Sean Ekins et al. NATURE MATERIALS
- Applications of machine learning in drug discovery and development
- (2019) Jessica Vamathevan et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting RIPK1 for the treatment of human diseases
- (2019) Alexei Degterev et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Astrocytes and Microglia as Potential Contributors to the Pathogenesis of C9orf72 Repeat Expansion-Associated FTLD and ALS
- (2019) Hannah Rostalski et al. Frontiers in Neuroscience
- DNA sensing by the cGAS–STING pathway in health and disease
- (2019) Mona Motwani et al. NATURE REVIEWS GENETICS
- BioBERT: a pre-trained biomedical language representation model for biomedical text mining
- (2019) Jinhyuk Lee et al. BIOINFORMATICS
- Detecting bursty terms in computer science research
- (2019) E. Tattershall et al. SCIENTOMETRICS
- Targeting the TIGIT-PVR immune checkpoint axis as novel therapeutic option in breast cancer
- (2019) Hauke Stamm et al. OncoImmunology
- Formation and Function of Mammalian Epithelia: Roles for Mechanosensitive PIEZO1 Ion Channels
- (2019) Teneale A. Stewart et al. Frontiers in Cell and Developmental Biology
- Estimation of clinical trial success rates and related parameters
- (2018) Chi Heem Wong et al. BIOSTATISTICS
- The research on gene-disease association based on text-mining of PubMed
- (2018) Jie Zhou et al. BMC BIOINFORMATICS
- Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection
- (2018) Shang Ma et al. CELL
- The brace helices of MLKL mediate interdomain communication and oligomerisation to regulate cell death by necroptosis
- (2018) Katherine A. Davies et al. CELL DEATH AND DIFFERENTIATION
- Recurrent Neural Network Model for Constructive Peptide Design
- (2018) Alex T. Müller et al. Journal of Chemical Information and Modeling
- MLKL Requires the Inositol Phosphate Code to Execute Necroptosis
- (2018) Cole M. Dovey et al. MOLECULAR CELL
- Chromosomal instability drives metastasis through a cytosolic DNA response
- (2018) Samuel F. Bakhoum et al. NATURE
- Genetic, transcriptional and post-translational regulation of the programmed death protein ligand 1 in cancer: biology and clinical correlations
- (2018) Ioannis Zerdes et al. ONCOGENE
- Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses
- (2018) Carlos Pardo-Pastor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Approaches to target tractability assessment – a practical perspective
- (2018) Kristin K. Brown et al. MedChemComm
- Oxidative stress preconditioning of mouse perivascular myogenic progenitors selects a subpopulation of cells with a distinct survival advantage in vitro and in vivo
- (2018) Cesare Gargioli et al. Cell Death & Disease
- Piezo1 is a mechanically activated ion channel and mediates pressure induced pancreatitis
- (2018) Joelle M.-J. Romac et al. Nature Communications
- Automatic Chemical Design Using a Data-Driven Continuous Representation of Molecules
- (2018) Rafael Gómez-Bombarelli et al. ACS Central Science
- C9orf72-mediated ALS and FTD: multiple pathways to disease
- (2018) Rubika Balendra et al. Nature Reviews Neurology
- TREM2 — a key player in microglial biology and Alzheimer disease
- (2018) Tyler K. Ulland et al. Nature Reviews Neurology
- Automatic extraction of gene-disease associations from literature using joint ensemble learning
- (2018) Balu Bhasuran et al. PLoS One
- Large-scale investigation of the reasons why potentially important genes are ignored
- (2018) Thomas Stoeger et al. PLOS BIOLOGY
- Deep reinforcement learning for de novo drug design
- (2018) Mariya Popova et al. Science Advances
- RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer
- (2018) Wei Wang et al. CANCER CELL
- Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice
- (2018) Xianjun Luo et al. GASTROENTEROLOGY
- Hippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
- (2018) Iván M. Moya et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases
- (2018) Junying Yuan et al. NATURE REVIEWS NEUROSCIENCE
- Epigenetic silencing of ZNF132 mediated by methylation-sensitive Sp1 binding promotes cancer progression in esophageal squamous cell carcinoma
- (2018) Dong Jiang et al. Cell Death & Disease
- Double-slit photoelectron interference in strong-field ionization of the neon dimer
- (2018) Maksim Kunitski et al. Nature Communications
- The Rise and Fall of a Scaffold: A Trend Analysis of Scaffolds in the Medicinal Chemistry Literature
- (2017) Barbara Zdrazil et al. JOURNAL OF MEDICINAL CHEMISTRY
- In silico prediction of novel therapeutic targets using gene–disease association data
- (2017) Enrico Ferrero et al. Journal of Translational Medicine
- Impeding Transcription of Expanded Microsatellite Repeats by Deactivated Cas9
- (2017) Belinda S. Pinto et al. MOLECULAR CELL
- Application of Generative Autoencoder in De Novo Molecular Design
- (2017) Thomas Blaschke et al. Molecular Informatics
- Mechanical stretch triggers rapid epithelial cell division through Piezo1
- (2017) S. A. Gudipaty et al. NATURE
- cGAS drives noncanonical-inflammasome activation in age-related macular degeneration
- (2017) Nagaraj Kerur et al. NATURE MEDICINE
- Mechanobiology of collective cell behaviours
- (2017) Benoit Ladoux et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanobiology of YAP and TAZ in physiology and disease
- (2017) Tito Panciera et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Activation of the STING-Dependent Type I Interferon Response Reduces Microglial Reactivity and Neuroinflammation
- (2017) Vidhu Mathur et al. NEURON
- Functional and Molecular Characterization of Mechanoinsensitive “Silent” Nociceptors
- (2017) Vincenzo Prato et al. Cell Reports
- Piezo2: A Candidate Biomarker for Visceral Hypersensitivity in Irritable Bowel Syndrome?
- (2017) Tao Bai et al. Journal of Neurogastroenterology and Motility
- NCBO Ontology Recommender 2.0: an enhanced approach for biomedical ontology recommendation
- (2017) Marcos Martínez-Romero et al. Journal of Biomedical Semantics
- Generating Focused Molecule Libraries for Drug Discovery with Recurrent Neural Networks
- (2017) Marwin H. S. Segler et al. ACS Central Science
- Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
- (2017) Michiru Nishita et al. Scientific Reports
- MLKL forms cation channels
- (2016) Bingqing Xia et al. CELL RESEARCH
- Recessive PIEZO2 stop mutation causes distal arthrogryposis with distal muscle weakness, scoliosis and proprioception defects
- (2016) Goknur Haliloglu et al. JOURNAL OF HUMAN GENETICS
- Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
- (2016) Keiko Nonomura et al. NATURE
- Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow
- (2016) Li Wang et al. NATURE
- Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
- (2016) Boris Strilic et al. NATURE
- Mechanosensory hair cells express two molecularly distinct mechanotransduction channels
- (2016) Zizhen Wu et al. NATURE NEUROSCIENCE
- TREM2 variants: new keys to decipher Alzheimer disease pathogenesis
- (2016) Marco Colonna et al. NATURE REVIEWS NEUROSCIENCE
- Bidirectional Transcriptional Inhibition as Therapy for ALS/FTD Caused by Repeat Expansion in C9orf72
- (2016) Jie Jiang et al. NEURON
- DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
- (2016) Janet Piñero et al. NUCLEIC ACIDS RESEARCH
- Disciplined approach to drug discovery and early development
- (2016) Robert M. Plenge Science Translational Medicine
- BioCreative V CDR task corpus: a resource for chemical disease relation extraction
- (2016) Jiao Li et al. Database-The Journal of Biological Databases and Curation
- Author Disambiguation in PubMed: Evidence on the Precision and Recall of Author-ity among NIH-Funded Scientists
- (2016) Marc J. Lerchenmueller et al. PLoS One
- The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease
- (2015) Christina M. Lill et al. Alzheimers & Dementia
- Extraction of relations between genes and diseases from text and large-scale data analysis: implications for translational research
- (2015) Àlex Bravo et al. BMC BIOINFORMATICS
- The Hippo pathway effector YAP controls mouse hepatic stellate cell activation
- (2015) Inge Mannaerts et al. JOURNAL OF HEPATOLOGY
- DISEASES: Text mining and data integration of disease–gene associations
- (2015) Sune Pletscher-Frankild et al. METHODS
- Necroptosis and its role in inflammation
- (2015) Manolis Pasparakis et al. NATURE
- Piezo2 is the principal mechanotransduction channel for proprioception
- (2015) Seung-Hyun Woo et al. NATURE NEUROSCIENCE
- An analysis of the attrition of drug candidates from four major pharmaceutical companies
- (2015) Michael J. Waring et al. NATURE REVIEWS DRUG DISCOVERY
- PolySearch2: a significantly improved text-mining system for discovering associations between human diseases, genes, drugs, metabolites, toxins and more
- (2015) Yifeng Liu et al. NUCLEIC ACIDS RESEARCH
- Suppression of systemic autoimmunity by the innate immune adaptor STING
- (2015) Shruti Sharma et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia
- (2015) Viktor Lukacs et al. Nature Communications
- Drug target prioritization by perturbed gene expression and network information
- (2015) Zerrin Isik et al. Scientific Reports
- Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit
- (2015) Thomas Bertero et al. Cell Reports
- Piezo1 links mechanical forces to red blood cell volume
- (2015) Stuart M Cahalan et al. eLife
- Growth rates of modern science: A bibliometric analysis based on the number of publications and cited references
- (2015) Lutz Bornmann et al. Journal of the Association for Information Science and Technology
- STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors
- (2014) Seng-Ryong Woo et al. IMMUNITY
- Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice
- (2014) S. B. Berger et al. JOURNAL OF IMMUNOLOGY
- Piezo2 is the major transducer of mechanical forces for touch sensation in mice
- (2014) Sanjeev S. Ranade et al. NATURE
- Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
- (2014) David Cook et al. NATURE REVIEWS DRUG DISCOVERY
- Homozygous TREM2 mutation in a family with atypical frontotemporal dementia
- (2014) Isabelle Le Ber et al. NEUROBIOLOGY OF AGING
- Activated STING in a Vascular and Pulmonary Syndrome
- (2014) Yin Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells
- (2014) Medha M. Pathak et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Piezo1, a mechanically activated ion channel, is required for vascular development in mice
- (2014) S. S. Ranade et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening
- (2014) Jouhyun Jeon et al. Genome Medicine
- TREM2Variant p.R47H as a Risk Factor for Sporadic Amyotrophic Lateral Sclerosis
- (2014) Janet Cady et al. JAMA Neurology
- Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
- (2013) Zhenyu Cai et al. NATURE CELL BIOLOGY
- TREM2 mutations are rare in a French cohort of patients with frontotemporal dementia
- (2013) Serena Lattante et al. NEUROBIOLOGY OF AGING
- A novel compound heterozygous mutation in TREM2 found in a Turkish frontotemporal dementia-like family
- (2013) Rita Guerreiro et al. NEUROBIOLOGY OF AGING
- TREM2 is associated with the risk of Alzheimer's disease in Spanish population
- (2013) Bruno A. Benitez et al. NEUROBIOLOGY OF AGING
- Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia
- (2013) Agustín Ruiz et al. NEUROBIOLOGY OF AGING
- Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia
- (2013) Elise Cuyvers et al. NEUROBIOLOGY OF AGING
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma
- (2013) Omid Hamid et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
- (2013) D. Sareen et al. Science Translational Medicine
- Drug Repositioning: A Machine-Learning Approach through Data Integration
- (2013) Francesco Napolitano et al. Journal of Cheminformatics
- Using Exome Sequencing to Reveal Mutations in TREM2 Presenting as a Frontotemporal Dementia–like Syndrome Without Bone Involvement
- (2013) Rita João Guerreiro et al. JAMA Neurology
- Automated design of ligands to polypharmacological profiles
- (2012) Jérémy Besnard et al. NATURE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomics
- (2012) D. Tabas-Madrid et al. NUCLEIC ACIDS RESEARCH
- Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis
- (2012) J. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RIP Kinase-Dependent Necrosis Drives Lethal Systemic Inflammatory Response Syndrome
- (2011) Linde Duprez et al. IMMUNITY
- Trends in the exploitation of novel drug targets
- (2011) Mathias Rask-Andersen et al. NATURE REVIEWS DRUG DISCOVERY
- TargetMine, an Integrated Data Warehouse for Candidate Gene Prioritisation and Target Discovery
- (2011) Yi-An Chen et al. PLoS One
- Computational Repositioning of the Anticonvulsant Topiramate for Inflammatory Bowel Disease
- (2011) J. T. Dudley et al. Science Translational Medicine
- DisGeNET: a Cytoscape plugin to visualize, integrate, search and analyze gene–disease networks
- (2010) Anna Bauer-Mehren et al. BIOINFORMATICS
- The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
- (2010) J. Cai et al. GENES & DEVELOPMENT
- How to improve R&D productivity: the pharmaceutical industry's grand challenge
- (2010) Steven M. Paul et al. NATURE REVIEWS DRUG DISCOVERY
- Author name disambiguation in MEDLINE
- (2009) Vetle I. Torvik et al. ACM Transactions on Knowledge Discovery from Data
- Extraction of semantic biomedical relations from text using conditional random fields
- (2008) Markus Bundschus et al. BMC BIOINFORMATICS
- Overview of BioCreative II gene mention recognition
- (2008) Larry Smith et al. GENOME BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started