Mechanosensory hair cells express two molecularly distinct mechanotransduction channels

Development and localization of reverse-polarity mechanotransducer channels in cochlear hair cells

(2016) Maryline Beurg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects ofTmc1 Beethovenmutation on mechanotransducer channel function in cochlear hair cells

(2015) Maryline Beurg et al.   JOURNAL OF GENERAL PHYSIOLOGY

Piezo2 is the principal mechanotransduction channel for proprioception

(2015) Seung-Hyun Woo et al.   NATURE NEUROSCIENCE

TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia

(2015) Kiyoto Kurima et al.   Cell Reports

Piezo1 links mechanical forces to red blood cell volume

(2015) Stuart M Cahalan et al.   eLife

Conductance and block of hair-cell mechanotransducer channels in transmembrane channel–like protein mutants

(2014) Maryline Beurg et al.   JOURNAL OF GENERAL PHYSIOLOGY

Transduction without Tip Links in Cochlear Hair Cells Is Mediated by Ion Channels with Permeation Properties Distinct from Those of the Mechano-Electrical Transducer Channel

(2014) W. Marcotti et al.   JOURNAL OF NEUROSCIENCE

Piezo2 is required for Merkel-cell mechanotransduction

(2014) Seung-Hyun Woo et al.   NATURE

TMIE Is an Essential Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2014) Bo Zhao et al.   NEURON

Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage

(2014) Whasil Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo1, a mechanically activated ion channel, is required for vascular development in mice

(2014) S. S. Ranade et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subunit determination of the conductance of hair-cell mechanotransducer channels

(2014) Maryline Beurg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of transmembrane channel–like proteins in the operation of hair cell mechanotransducer channels

(2013) Kyunghee X. Kim et al.   JOURNAL OF GENERAL PHYSIOLOGY

A Prestin Motor in Chicken Auditory Hair Cells: Active Force Generation in a Nonmammalian Species

(2013) Maryline Beurg et al.   NEURON

TMC1 and TMC2 Are Components of the Mechanotransduction Channel in Hair Cells of the Mammalian Inner Ear

(2013) Bifeng Pan et al.   NEURON

Active cochlear amplification is dependent on supporting cell gap junctions

(2013) Yan Zhu et al.   Nature Communications

A role for Piezo2 in EPAC1-dependent mechanical allodynia

(2013) N Eijkelkamp et al.   Nature Communications

TMHS Is an Integral Component of the Mechanotransduction Machinery of Cochlear Hair Cells

(2012) Wei Xiong et al.   CELL

Kinocilia Mediate Mechanosensitivity in Developing Zebrafish Hair Cells

(2012) Katie S. Kindt et al.   DEVELOPMENTAL CELL

Developmental changes in the cochlear hair cell mechanotransducer channel and their regulation by transmembrane channel–like proteins

(2012) Kyunghee X. Kim et al.   JOURNAL OF GENERAL PHYSIOLOGY

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Inflammatory Signals Enhance Piezo2-Mediated Mechanosensitive Currents

(2012) Adrienne E. Dubin et al.   Cell Reports

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

(2011) Yoshiyuki Kawashima et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutations in Protocadherin 15 and Cadherin 23 Affect Tip Links and Mechanotransduction in Mammalian Sensory Hair Cells

(2011) Kumar N. Alagramam et al.   PLoS One

Topology of Transmembrane Channel-like Gene 1 Protein

(2010) Valentina Labay et al.   BIOCHEMISTRY

Calcium Balance and Mechanotransduction in Rat Cochlear Hair Cells

(2010) Maryline Beurg et al.   JOURNAL OF NEUROPHYSIOLOGY

A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment

(2010) Rachel E Hardisty-Hughes et al.   Nature Protocols

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Mutations in LOXHD1, an Evolutionarily Conserved Stereociliary Protein, Disrupt Hair Cell Function in Mice and Cause Progressive Hearing Loss in Humans

(2009) Nicolas Grillet et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mechanotransduction by Hair Cells: Models, Molecules, and Mechanisms

(2009) Peter G. Gillespie et al.   CELL

Tonotopic Gradient in the Developmental Acquisition of Sensory Transduction in Outer Hair Cells of the Mouse Cochlea

(2009) Andrea Lelli et al.   JOURNAL OF NEUROPHYSIOLOGY

Localization of inner hair cell mechanotransducer channels using high-speed calcium imaging

(2009) Maryline Beurg et al.   NATURE NEUROSCIENCE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Harmonin Mutations Cause Mechanotransduction Defects in Cochlear Hair Cells

(2009) Nicolas Grillet et al.   NEURON

Cochlear Outer Hair Cell Motility

(2008) Jonathan Ashmore   PHYSIOLOGICAL REVIEWS