A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A ligand-insensitive UNC5B splicing isoform regulates angiogenesis by promoting apoptosis
Authors
Keywords
-
Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-08-11
DOI
10.1038/s41467-021-24998-6
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genetic lineage tracing reveals poor angiogenic potential of cardiac endothelial cells
- (2020) Tea Kocijan et al. CARDIOVASCULAR RESEARCH
- Alternative splicing in endothelial cells: novel therapeutic opportunities in cancer angiogenesis
- (2020) Anna Di Matteo et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- TAK1 regulates endothelial cell necroptosis and tumor metastasis
- (2019) Lida Yang et al. CELL DEATH AND DIFFERENTIATION
- The Alternative Splicing Regulator Nova2 Constrains Vascular Erk Signaling to Limit Specification of the Lymphatic Lineage
- (2019) Sungmin Baek et al. DEVELOPMENTAL CELL
- A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing
- (2019) Francesca Angiolini et al. eLife
- Response of the neurovascular unit to brain metastatic breast cancer cells
- (2019) János Haskó et al. Acta Neuropathologica Communications
- Alternative Splicing Regulatory Networks: Functions, Mechanisms, and Evolution
- (2019) Jernej Ule et al. MOLECULAR CELL
- Gene Expression Profiles Controlled by the Alternative Splicing Factor Nova2 in Endothelial Cells
- (2019) Elisa Belloni et al. Cells
- TSVdb: a web-tool for TCGA splicing variants analysis
- (2018) Wenjie Sun et al. BMC GENOMICS
- Regulation of apoptosis by an intrinsically disordered region of Bcl-xL
- (2018) Ariele Viacava Follis et al. Nature Chemical Biology
- Alternative RNA splicing in the endothelium mediated in part by Rbfox2 regulates the arterial response to low flow
- (2018) Patrick A Murphy et al. eLife
- Diversification of the muscle proteome through alternative splicing
- (2018) Kiran Nakka et al. Skeletal Muscle
- Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients
- (2018) André Kahles et al. CANCER CELL
- Upregulation of the alternative splicing factor NOVA2 in colorectal cancer vasculature
- (2018) Stefania Gallo et al. OncoTargets and Therapy
- An atlas of alternative splicing profiles and functional associations reveals new regulatory programs and genes that simultaneously express multiple major isoforms
- (2017) Javier Tapial et al. GENOME RESEARCH
- EMT and stemness: flexible processes tuned by alternative splicing in development and cancer progression
- (2017) Davide Pradella et al. Molecular Cancer
- HCMDB: the human cancer metastasis database
- (2017) Guantao Zheng et al. NUCLEIC ACIDS RESEARCH
- Alu RNA accumulation induces epithelial-to-mesenchymal transition by modulating miR-566 and is associated with cancer progression
- (2017) F Di Ruocco et al. ONCOGENE
- UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses
- (2017) Darshan S. Chandrashekar et al. NEOPLASIA
- Application of a non-hazardous vital dye for cell counting with automated cell counters
- (2016) Soo In Kim et al. ANALYTICAL BIOCHEMISTRY
- Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis
- (2016) Boris Strilic et al. NATURE
- NOVA2-mediated RNA regulation is required for axonal pathfinding during development
- (2016) Yuhki Saito et al. eLife
- Mechanisms of Vessel Pruning and Regression
- (2015) Claudia Korn et al. DEVELOPMENTAL CELL
- Alternative Splicing in the Mammalian Nervous System: Recent Insights into Mechanisms and Functional Roles
- (2015) Bushra Raj et al. NEURON
- TCGASpliceSeq a compendium of alternative mRNA splicing in cancer
- (2015) Michael Ryan et al. NUCLEIC ACIDS RESEARCH
- The alternative splicing factor Nova2 regulates vascular development and lumen formation
- (2015) Costanza Giampietro et al. Nature Communications
- Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis
- (2015) Mélanie Tichet et al. Nature Communications
- PROGgeneV2: enhancements on the existing database
- (2015) Chirayu Pankaj Goswami et al. BMC CANCER
- Endothelial deficiency of L1 reduces tumor angiogenesis and promotes vessel normalization
- (2014) Elena Magrini et al. JOURNAL OF CLINICAL INVESTIGATION
- FLRT Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
- (2014) Elena Seiradake et al. NEURON
- RBPmap: a web server for mapping binding sites of RNA-binding proteins
- (2014) Inbal Paz et al. NUCLEIC ACIDS RESEARCH
- Structures of netrin-1 bound to two receptors provide insight into its axon guidance mechanism
- (2014) K. Xu et al. SCIENCE
- The alternative splicing side of cancer
- (2014) Giuseppe Biamonti et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Regulation of FAS Exon Definition and Apoptosis by the Ewing Sarcoma Protein
- (2014) Maria Paola Paronetto et al. Cell Reports
- Platelet-Derived Nucleotides Promote Tumor-Cell Transendothelial Migration and Metastasis via P2Y2 Receptor
- (2013) Dagmar Schumacher et al. CANCER CELL
- Alternative splicing of intrinsically disordered regions and rewiring of protein interactions
- (2013) Marija Buljan et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Expression of unc5 family genes in zebrafish brain during embryonic development
- (2013) Bin Yang et al. GENE EXPRESSION PATTERNS
- Control of alternative splicing in immune responses: many regulators, many predictions, much still to learn
- (2013) Nicole M. Martinez et al. IMMUNOLOGICAL REVIEWS
- iCLIP: Protein–RNA interactions at nucleotide resolution
- (2013) Ina Huppertz et al. METHODS
- HnRNP A1 controls a splicing regulatory circuit promoting mesenchymal-to-epithelial transition
- (2013) S. Bonomi et al. NUCLEIC ACIDS RESEARCH
- Hallmarks of alternative splicing in cancer
- (2013) S Oltean et al. ONCOGENE
- Tumor microenvironment-associated modifications of alternative splicing
- (2013) J.-P. Brosseau et al. RNA
- Tailoring of Membrane Proteins by Alternative Splicing of Pre-mRNA
- (2012) Kathleen F. Mittendorf et al. BIOCHEMISTRY
- Overlapping and divergent signaling pathways of N-cadherin and VE-cadherin in endothelial cells
- (2012) C. Giampietro et al. BLOOD
- Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway
- (2012) Monika Julia Wolf et al. CANCER CELL
- TGF- 1 Induces Endothelial Cell Apoptosis by Shifting VEGF Activation of p38MAPK from the Prosurvival p38 to Proapoptotic p38
- (2012) G. Ferrari et al. MOLECULAR CANCER RESEARCH
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Analysis of alternative splicing associated with aging and neurodegeneration in the human brain
- (2011) J. R. Tollervey et al. GENOME RESEARCH
- SpliceAid 2: A database of human splicing factors expression data and RNA target motifs
- (2011) Francesco Piva et al. HUMAN MUTATION
- The Ewing Sarcoma Protein Regulates DNA Damage-Induced Alternative Splicing
- (2011) Maria Paola Paronetto et al. MOLECULAR CELL
- Sam68 marks the transcriptionally active stages of spermatogenesis and modulates alternative splicing in male germ cells
- (2011) Maria Paola Paronetto et al. NUCLEIC ACIDS RESEARCH
- Abrogation of Junctional Adhesion Molecule-A Expression Induces Cell Apoptosis and Reduces Breast Cancer Progression
- (2011) Masato Murakami et al. PLoS One
- Vessel abnormalization: another hallmark of cancer?Molecular mechanisms and therapeutic implications
- (2010) Katrien De Bock et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Tumor-induced endothelial cell apoptosis: Roles of NAD(P)H oxidase-derived reactive oxygen species
- (2010) Ruei-Zeng Lin et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The Dependence Receptor UNC5H2/B Triggers Apoptosis via PP2A-Mediated Dephosphorylation of DAP Kinase
- (2010) Céline Guenebeaud et al. MOLECULAR CELL
- Axon Guidance Molecules in Vascular Patterning
- (2010) R. H. Adams et al. Cold Spring Harbor Perspectives in Biology
- Alternative pre-mRNA splicing switches modulate gene expression in late erythropoiesis
- (2009) M. L. Yamamoto et al. BLOOD
- Interfering with multimerization of netrin-1 receptors triggers tumor cell death
- (2009) F Mille et al. CELL DEATH AND DIFFERENTIATION
- Inhibition of Endothelial Cell Apoptosis by Netrin-1 during Angiogenesis
- (2009) Marie Castets et al. DEVELOPMENTAL CELL
- Transforming growth factor-beta 1 (TGF-β1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis
- (2009) Giovanni Ferrari et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Autoinhibition of UNC5b Revealed by the Cytoplasmic Domain Structure of the Receptor
- (2009) Rui Wang et al. MOLECULAR CELL
- The netrin receptor UNC5B promotes angiogenesis in specific vascular beds
- (2008) S. Navankasattusas et al. DEVELOPMENT
- Alternative isoform regulation in human tissue transcriptomes
- (2008) Eric T. Wang et al. NATURE
- Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
- (2008) Qun Pan et al. NATURE GENETICS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now