Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes
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Title
Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes
Authors
Keywords
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Journal
Cell Death & Disease
Volume 12, Issue 7, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-07-03
DOI
10.1038/s41419-021-03952-w
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Related references
Note: Only part of the references are listed.- Multitasking guardian of mitochondrial quality: Parkin function and Parkinson’s disease
- (2021) Iryna Kamienieva et al. Translational Neurodegeneration
- Mitophagy: An Emerging Role in Aging and Age-Associated Diseases
- (2020) Guo Chen et al. Frontiers in Cell and Developmental Biology
- Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
- (2019) Antonio Cuadrado et al. NATURE REVIEWS DRUG DISCOVERY
- Emerging therapies in Parkinson disease — repurposed drugs and new approaches
- (2019) Ahmad Elkouzi et al. Nature Reviews Neurology
- Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
- (2019) Evandro F. Fang et al. NATURE NEUROSCIENCE
- Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy
- (2019) Eleni N. Tsakiri et al. Autophagy
- Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics
- (2019) Sentiljana Gumeni et al. Redox Biology
- Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand
- (2018) Thomas G. McWilliams et al. Cell Metabolism
- Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance
- (2018) Sarah Pickles et al. CURRENT BIOLOGY
- Basal mitophagy is widespread inDrosophilabut minimally affected by loss of Pink1 or parkin
- (2018) Juliette J. Lee et al. JOURNAL OF CELL BIOLOGY
- The coming of age of chaperone-mediated autophagy
- (2018) Susmita Kaushik et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Mechanisms of mitophagy in cellular homeostasis, physiology and pathology
- (2018) Konstantinos Palikaras et al. NATURE CELL BIOLOGY
- Life, death and autophagy
- (2018) Johnna Doherty et al. NATURE CELL BIOLOGY
- Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing
- (2018) Barry Boland et al. NATURE REVIEWS DRUG DISCOVERY
- Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation
- (2018) Eleni N. Tsakiri et al. AGING CELL
- Drosophila Models of Sporadic Parkinson’s Disease
- (2018) Emi Nagoshi INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms
- (2017) Jesse S. Kerr et al. TRENDS IN NEUROSCIENCES
- Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases
- (2017) Marta Pajares et al. Redox Biology
- On the linkage between the ubiquitin-proteasome system and the mitochondria
- (2016) Gilad Lehmann et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The mitochondrial kinase PINK1: functions beyond mitophagy
- (2016) Aaron Voigt et al. JOURNAL OF NEUROCHEMISTRY
- Mitochondrial dysfunction in Parkinson's disease
- (2016) Anindita Bose et al. JOURNAL OF NEUROCHEMISTRY
- An evolutionarily conserved pathway controls proteasome homeostasis
- (2016) Adrien Rousseau et al. NATURE
- Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease
- (2016) Sentiljana Gumeni et al. Oxidative Medicine and Cellular Longevity
- Mitochondria, autophagy and age-associated neurodegenerative diseases: New insights into a complex interplay
- (2015) Eirini Lionaki et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Balancing mitochondrial biogenesis and mitophagy to maintain energy metabolism homeostasis
- (2015) K Palikaras et al. CELL DEATH AND DIFFERENTIATION
- The emerging role of Nrf2 in mitochondrial function
- (2015) Albena T. Dinkova-Kostova et al. FREE RADICAL BIOLOGY AND MEDICINE
- The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications
- (2015) Thomas M. Durcan et al. GENES & DEVELOPMENT
- Proteostasis and aging
- (2015) Susmita Kaushik et al. NATURE MEDICINE
- The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
- (2015) Alicia M. Pickrell et al. NEURON
- Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease
- (2015) Brent J. Ryan et al. TRENDS IN BIOCHEMICAL SCIENCES
- AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
- (2014) F Strappazzon et al. CELL DEATH AND DIFFERENTIATION
- PMI: A ΔΨm Independent Pharmacological Regulator of Mitophagy
- (2014) Daniel A. East et al. CHEMISTRY & BIOLOGY
- ROS Function in Redox Signaling and Oxidative Stress
- (2014) Michael Schieber et al. CURRENT BIOLOGY
- Cellular mechanisms and physiological consequences of redox-dependent signalling
- (2014) Kira M. Holmström et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- PPARγ and PGC-1α as Therapeutic Targets in Parkinson’s
- (2014) Juan Carlos Corona et al. NEUROCHEMICAL RESEARCH
- PINK1 is degraded through the N-end rule pathway
- (2013) Koji Yamano et al. Autophagy
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Differential regulation of proteasome functionality in reproductive vs. somatic tissues of Drosophila during aging or oxidative stress
- (2013) Eleni N. Tsakiri et al. FASEB JOURNAL
- Parkin-catalyzed Ubiquitin-Ester Transfer Is Triggered by PINK1-dependent Phosphorylation
- (2013) Masahiro Iguchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
- (2012) Michael Lazarou et al. DEVELOPMENTAL CELL
- Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences
- (2012) Nicole Exner et al. EMBO JOURNAL
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging
- (2010) Fabio Demontis et al. CELL
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
- (2010) Masaaki Komatsu et al. NATURE CELL BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
- (2009) Ruben K. Dagda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PINK1 Defect Causes Mitochondrial Dysfunction, Proteasomal Deficit and α-Synuclein Aggregation in Cell Culture Models of Parkinson's Disease
- (2009) Wencheng Liu et al. PLoS One
- PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria
- (2008) Shih-Ching Lo et al. EXPERIMENTAL CELL RESEARCH
- Mitophagy in Yeast Occurs through a Selective Mechanism
- (2008) Tomotake Kanki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
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