Genome-Wide Essentiality Analysis of Mycobacterium abscessus by Saturated Transposon Mutagenesis and Deep Sequencing
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Genome-Wide Essentiality Analysis of
Mycobacterium abscessus
by Saturated Transposon Mutagenesis and Deep Sequencing
Authors
Keywords
-
Journal
mBio
Volume -, Issue -, Pages -
Publisher
American Society for Microbiology
Online
2021-06-15
DOI
10.1128/mbio.01049-21
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Non-tuberculous mycobacteria and the rise of Mycobacterium abscessus
- (2020) Matt D. Johansen et al. NATURE REVIEWS MICROBIOLOGY
- Identifying the essential genes of Mycobacterium avium subsp. hominissuis with Tn-Seq using a rank-based filter procedure
- (2020) William M. Matern et al. Scientific Reports
- Structure‐Based Design and Synthesis of Piperidinol‐Containing Molecules as New Mycobacterium abscessus Inhibitors
- (2020) Jérôme Ruyck et al. ChemistryOpen
- Advancement of GyrB Inhibitors for Treatment of Infections Caused by Mycobacterium tuberculosis and Non-tuberculous Mycobacteria
- (2020) Suzanne S. Stokes et al. ACS Infectious Diseases
- A Simplified and Efficient Method for Himar-1 Transposon Sequencing in Bacteria, Demonstrated by Creation and Analysis of a Saturated Transposon-Mutant Library in Mycobacterium abscessus
- (2020) Mark Foreman et al. mSystems
- Indole-2-carboxamides are Active Against an Acute Mycobacterium abscessus Infected Mouse Model
- (2019) Amit N. Pandya et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- OrthoVenn2: a web server for whole-genome comparison and annotation of orthologous clusters across multiple species
- (2019) Ling Xu et al. NUCLEIC ACIDS RESEARCH
- Detection and Molecular Characterization of Amikacin-resistant Mycobacterium abscessus Isolated from Patients with Pulmonary Disease
- (2019) Mingyan Wu et al. Journal of Global Antimicrobial Resistance
- The TetR-family transcription factor MAB_2299c regulates the expression of two distinct MmpS-MmpL efflux pumps involved in cross-resistance to clofazimine and bedaquiline in Mycobacterium abscessus
- (2019) Ana Victoria Gutiérrez et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Insights From the Genome Sequence of Mycobacterium paragordonae, a Potential Novel Live Vaccine for Preventing Mycobacterial Infections: The Putative Role of Type VII Secretion Systems for an Intracellular Lifestyle Within Free-Living Environmental Predators
- (2019) Byoung-Jun Kim et al. Frontiers in Microbiology
- Genomewide Assessment of Mycobacterium tuberculosis Conditionally Essential Metabolic Pathways
- (2019) Yusuke Minato et al. mSystems
- Mode-of-action profiling reveals glutamine synthetase as a collateral metabolic vulnerability of M. tuberculosis to bedaquiline
- (2019) Zhe Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differential sensitivity of mycobacteria to isoniazid is related to differences in KatG-mediated enzymatic activation of the drug.
- (2019) Tali H. Reingewertz et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Mycobacterium abscessus, an Emerging and Worrisome Pathogen among Cystic Fibrosis Patients
- (2019) Degiacomi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Comparative Analysis of Whole-Genome and Methylome Profiles of a Smooth and a Rough Mycobacterium abscessus Clinical Strain
- (2019) Chiranjibi Chhotaray et al. G3-Genes Genomes Genetics
- Global Assessment of Mycobacterium avium subsp. hominissuis Genetic Requirement for Growth and Virulence
- (2019) Marte S. Dragset et al. mSystems
- Two DD-Carboxypeptidases from Mycobacterium smegmatis Affect Cell Surface Properties through Regulation of Peptidoglycan Cross-Linking and Glycopeptidolipids
- (2018) Satya Deo Pandey et al. JOURNAL OF BACTERIOLOGY
- The transpeptidase PbpA and noncanonical transglycosylase RodA ofMycobacterium tuberculosisplay important roles in regulating bacterial cell lengths
- (2018) Divya Arora et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Kinetics and structural features of dimeric glutamine-dependent bacterial NAD+synthetases suggest evolutionary adaptation to available metabolites
- (2018) Adrian Richard Schenberger Santos et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of genes required forMycobacterium abscessusgrowth in vivo with a prominent role of the ESX-4 locus
- (2018) Laura Laencina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanistic and Structural Insights Into the Unique TetR-Dependent Regulation of a Drug Efflux Pump in Mycobacterium abscessus
- (2018) Matthias Richard et al. Frontiers in Microbiology
- In Vitro Susceptibility Testing of a Novel Benzimidazole, SPR719, Against Nontuberculous Mycobacteria
- (2018) Barbara A. Brown-Elliott et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In Vitro Susceptibility Testing of Bedaquiline Against Mycobacterium abscessus Complex
- (2018) Barbara A. Brown-Elliott et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Targeting Mycolic Acid Transport by Indole-2-carboxamides for the Treatment of Mycobacterium abscessus Infections
- (2017) Alan P. Kozikowski et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mycobacterium abscessus ESX-3 plays an important role in host inflammatory and pathological responses during infection
- (2017) Yi Sak Kim et al. MICROBES AND INFECTION
- Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis
- (2017) Michael A. DeJesus et al. mBio
- An Amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase is required for mycobacterial cell division
- (2017) Sibusiso Senzani et al. Scientific Reports
- Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance
- (2016) Yu-Shan Cheng et al. BIOCHEMISTRY
- Functional characterization of the Mycobacterium abscessus genome coupled with condition specific transcriptomics reveals conserved molecular strategies for host adaptation and persistence
- (2016) Aleksandra A. Miranda-CasoLuengo et al. BMC GENOMICS
- Mycobacterial Pan-Genome Analysis Suggests Important Role of Plasmids in the Radiation of Type VII Secretion Systems
- (2016) Emilie Dumas et al. Genome Biology and Evolution
- Intrinsic rifamycin resistance ofMycobacterium abscessusis mediated by ADP-ribosyltransferase MAB_0591
- (2016) Anna Rominski et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Emergence ofmmpT5Variants during Bedaquiline Treatment of Mycobacterium intracellulare Lung Disease
- (2016) David C. Alexander et al. JOURNAL OF CLINICAL MICROBIOLOGY
- A new piperidinol derivative targeting mycolic acid transport inMycobacterium abscessus
- (2016) Christian Dupont et al. MOLECULAR MICROBIOLOGY
- Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium
- (2016) Josephine M. Bryant et al. SCIENCE
- Peptidoglycan synthesis inMycobacterium tuberculosisis organized into networks with varying drug susceptibility
- (2015) Karen J. Kieser et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Essential genome ofPseudomonas aeruginosain cystic fibrosis sputum
- (2015) Keith H. Turner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRANSIT - A Software Tool for Himar1 TnSeq Analysis
- (2015) Michael A. DeJesus et al. PLoS Computational Biology
- The Role of Superoxide Dismutase in the Survival of Mycobacterium tuberculosis in Macrophages
- (2015) Dan Liao et al. JAPANESE JOURNAL OF INFECTIOUS DISEASES
- A Novel Inhibitor of Gyrase B Is a Potent Drug Candidate for Treatment of Tuberculosis and Nontuberculosis Mycobacterial Infections
- (2014) Christopher P. Locher et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Trimmomatic: a flexible trimmer for Illumina sequence data
- (2014) Anthony M. Bolger et al. BIOINFORMATICS
- Genome analysis reveals three genomospecies in Mycobacterium abscessus
- (2014) Mohamed Sassi et al. BMC GENOMICS
- Comparative genomics for mycobacterial peptidoglycan remodelling enzymes reveals extensive genetic multiplicity
- (2014) Edith Machowski et al. BMC MICROBIOLOGY
- Folate Pathway Disruption Leads to Critical Disruption of Methionine Derivatives in Mycobacterium tuberculosis
- (2014) Molly R. Nixon et al. CHEMISTRY & BIOLOGY
- Mycobacterium tuberculosisenoyl-acyl carrier protein reductase inhibitors as potential antituberculotics: development in the past decade
- (2014) Ondrej Holas et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Metabolic and Bactericidal Effects of Targeted Suppression of NadD and NadE Enzymes in Mycobacteria
- (2014) I. A. Rodionova et al. mBio
- A Comprehensive tRNA Deletion Library Unravels the Genetic Architecture of the tRNA Pool
- (2014) Zohar Bloom-Ackermann et al. PLoS Genetics
- The structure of Rv3717 reveals a novel amidase fromMycobacterium tuberculosis
- (2013) Atul Kumar et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structures of free and inhibited forms of theL,D-transpeptidase LdtMt1fromMycobacterium tuberculosis
- (2013) Stefania Correale et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- A Hidden Markov Model for identifying essential and growth-defect regions in bacterial genomes from transposon insertion sequencing data
- (2013) Michael A DeJesus et al. BMC BIOINFORMATICS
- Characterization of broad-spectrum Mycobacterium abscessus class A -lactamase
- (2013) D. Soroka et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- The MprB Extracytoplasmic Domain Negatively Regulates Activation of the Mycobacterium tuberculosis MprAB Two-Component System
- (2013) D. J. Bretl et al. JOURNAL OF BACTERIOLOGY
- para-Aminosalicylic Acid Is a Prodrug Targeting Dihydrofolate Reductase inMycobacterium tuberculosis
- (2013) Jun Zheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A genetic strategy to identify targets for the development of drugs that prevent bacterial persistence
- (2013) J.-H. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mycobacterium tuberculosis possesses an unusual tmRNA rescue system
- (2013) Yoann Personne et al. TUBERCULOSIS
- Activities of Moxifloxacin in Combination with Macrolides against Clinical Isolates of Mycobacterium abscessus and Mycobacterium massiliense
- (2012) Go-Eun Choi et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Dose-Ranging Comparison of Rifampin and Rifapentine in Two Pathologically Distinct Murine Models of Tuberculosis
- (2012) Ian M. Rosenthal et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The Antifolates
- (2012) Michele Visentin et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Conditional Gene Expression in Mycobacterium abscessus
- (2011) Mélanie Cortes et al. PLoS One
- ARNold: A web tool for the prediction of Rho-independent transcription terminators
- (2011) Magali Naville et al. RNA Biology
- Networks of Gene Sharing among 329 Proteobacterial Genomes Reveal Differences in Lateral Gene Transfer Frequency at Different Phylogenetic Depths
- (2010) T. Kloesges et al. MOLECULAR BIOLOGY AND EVOLUTION
- The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin
- (2010) Radhika Gupta et al. NATURE MEDICINE
- ATP Synthase Inhibition of Mycobacterium avium Is Not Bactericidal
- (2009) N. Lounis et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Novel Gene, erm(41), Confers Inducible Macrolide Resistance to Clinical Isolates of Mycobacterium abscessus but Is Absent from Mycobacterium chelonae
- (2009) K. A. Nash et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The resuscitation-promoting factors ofMycobacterium tuberculosisare required for virulence and resuscitation from dormancy but are collectively dispensable for growthin vitro
- (2009) Bavesh D. Kana et al. MOLECULAR MICROBIOLOGY
- Non Mycobacterial Virulence Genes in the Genome of the Emerging Pathogen Mycobacterium abscessus
- (2009) Fabienne Ripoll et al. PLoS One
- Systematic Genetic Nomenclature for Type VII Secretion Systems
- (2009) Wilbert Bitter et al. PLoS Pathogens
- Construction of Mycobacterium abscessus Defined Glycopeptidolipid Mutants: Comparison of Genetic Tools
- (2008) H. Medjahed et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- EmbA is an essential arabinosyltransferase in Mycobacterium tuberculosis
- (2008) A. G. Amin et al. MICROBIOLOGY-SGM
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started