Combinatorial Approaches for Cancer Treatment Using Oncolytic Viruses: Projecting the Perspectives through Clinical Trials Outcomes

Real-life use of talimogene laherparepvec (T-VEC) in melanoma patients in centers in Austria, Switzerland and Germany

(2021) Julia Maria Ressler et al.   Journal for ImmunoTherapy of Cancer

Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma

(2021) Georgia M Beasley et al.   Journal for ImmunoTherapy of Cancer

Efficient delivery of oncolytic enterovirus by carrier cell line NK-92

(2021) Elizaveta Sergeevna Podshivalova et al.   Molecular Therapy-Oncolytics

Recommendations for the nomenclature of enteroviruses and rhinoviruses

(2020) P. Simmonds et al.   ARCHIVES OF VIROLOGY

Exploiting pre-existing immunity to enhance oncolytic cancer immunotherapy

(2020) Siri Tähtinen et al.   CANCER RESEARCH

Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor

(2020) Simon Jenni et al.   Cell Reports

Human Papillomavirus E6 and E7: The Cervical Cancer Hallmarks and Targets for Therapy

(2020) Asmita Pal et al.   Frontiers in Microbiology

Repurposing infectious disease vaccines for intratumoral immunotherapy

(2020) Ignacio Melero et al.   Journal for ImmunoTherapy of Cancer

Ofranergene obadenovec (VB-111) in platinum-resistant ovarian cancer; favorable response rates in a phase I/II study are associated with an immunotherapeutic effect

(2020) Rebecca C. Arend et al.   GYNECOLOGIC ONCOLOGY

An open-label, single-arm, phase II clinical trial of RP1, an enhanced potency oncolytic herpes virus, combined with nivolumab in four solid tumor types: Initial results from the skin cancer cohorts.

(2020) Mark R. Middleton et al.   JOURNAL OF CLINICAL ONCOLOGY

Relationship of infusion duration to safety, efficacy, and pharmacodynamics (PD): Second part of a phase I-II study using VSV-IFNβ-NIS (VV1) oncolytic virus in patients with refractory solid tumors.

(2020) Jaime R. Merchan et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety, Tumor Reduction, and Clinical Impact of Zika Virus Injection in Dogs with Advanced-Stage Brain Tumors

(2020) Carolini Kaid et al.   MOLECULAR THERAPY

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

(2020) Lorenzo Galluzzi et al.   Journal for ImmunoTherapy of Cancer

Assessing the oncolytic potential of rotavirus on mouse myeloma cell line Sp2/0-Ag14

(2020) Rafael A. Guerrero et al.   Biomedica

CAR-T Cell Therapies: An Overview of Clinical Studies Supporting Their Approved Use against Acute Lymphoblastic Leukemia and Large B-Cell Lymphomas

(2020) Aamir Ahmad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced rectal cancer (CEDAR)

(2020) Séan M. O’Cathail et al.   Radiation Oncology

Comparative efficacy of cemiplimab versus other systemic treatments for advanced cutaneous squamous cell carcinoma

(2020) Sam Keeping et al.   Future Oncology

Clinical Application of Oncolytic Viruses: A Systematic Review

(2020) Mary Cook et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies

(2020) Edurne Rujas et al.   Nature Communications

Clinical landscape of oncolytic virus research in 2020

(2020) Nicholas Macedo et al.   Journal for ImmunoTherapy of Cancer

Oncolytic Viruses and Immune Checkpoint Inhibitors: Preclinical Developments to Clinical Trials

(2020) June Kyu Hwang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Newcastle Disease Virus at the Forefront of Cancer Immunotherapy

(2020) Bharat Burman et al.   Cancers

A phase 1 dose escalation study of the oncolytic adenovirus enadenotucirev, administered intravenously to patients with epithelial solid tumors (EVOLVE)

(2019) Jean-Pascal Machiels et al.   Journal for ImmunoTherapy of Cancer

Two roads for oncolytic immunotherapy development

(2019) Howard L. Kaufman et al.   Journal for ImmunoTherapy of Cancer

Phase III Trial of PROSTVAC in Asymptomatic or Minimally Symptomatic Metastatic Castration-Resistant Prostate Cancer

(2019) James L. Gulley et al.   JOURNAL OF CLINICAL ONCOLOGY

Poxvirus Oncolytic virotherapy

(2019) Lino E. Torres-Domínguez et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Abscopal effect when combining oncolytic adenovirus and checkpoint inhibitor in a humanized NOG mouse model of melanoma

(2019) Lukasz Kuryk et al.   JOURNAL OF MEDICAL VIROLOGY

Changes to virus taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2019)

(2019) Peter J. Walker et al.   ARCHIVES OF VIROLOGY

Viral targeting of non-muscle invasive bladder cancer and priming of anti-tumour immunity following intravesical Coxsackievirus A21

(2019) Nicola E Annels et al.   CLINICAL CANCER RESEARCH

Achieving systemic delivery of oncolytic viruses

(2019) Claudia Hill et al.   Expert Opinion on Drug Delivery

Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy

(2019) Julia Niemann et al.   Nature Communications

Vaccinia-based oncolytic immunotherapy Pexastimogene Devacirepvec in patients with advanced hepatocellular carcinoma after sorafenib failure: a randomized multicenter Phase IIb trial (TRAVERSE)

(2019) M. Moehler et al.   OncoImmunology

First-in-human study of TK-positive oncolytic vaccinia virus delivered by adipose stromal vascular fraction cells

(2019) Boris R. Minev et al.   Journal of Translational Medicine

Recombinant vesicular stomatitis virus vector vaccines for WHO blueprint priority pathogens

(2019) Anahita Fathi et al.   Human Vaccines & Immunotherapeutics

Development of a new fusion-enhanced oncolytic immunotherapy platform based on herpes simplex virus type 1

(2019) Suzanne Thomas et al.   Journal for ImmunoTherapy of Cancer

1213PSingle intravenous preoperative administration of the oncolytic virus Pexa-Vec to prime anti-tumour immunity

(2019) A Samson et al.   ANNALS OF ONCOLOGY

Pembrolizumab in Combination with the Oncolytic Virus Pelareorep and Chemotherapy in Patients with Advanced Pancreatic Adenocarcinoma: A Phase Ib Study

(2019) Devalingam Mahalingam et al.   CLINICAL CANCER RESEARCH

Repurposing the yellow fever vaccine for intratumoral immunotherapy

(2019) Maria Angela Aznar et al.   EMBO Molecular Medicine

ICTV Virus Taxonomy Profile: Paramyxoviridae

(2019) Bert Rima et al.   JOURNAL OF GENERAL VIROLOGY

Experimental evolution generates novel oncolytic vesicular stomatitis viruses with improved replication in virus-resistant pancreatic cancer cells

(2019) Sara L. Seegers et al.   JOURNAL OF VIROLOGY

Treatment of a stage III rima glottidis patient with the oncolytic virus Rigvir

(2019) Guna Proboka et al.   MEDICINE

Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4

(2019) Shuang Qin et al.   Molecular Cancer

Intratumoral Immunotherapy—Update 2019

(2019) Omid Hamid et al.   ONCOLOGIST

A Randomized Double-Blind Phase II Study of the Seneca Valley Virus (NTX-010) versus Placebo for Patients with Extensive-Stage SCLC (ES SCLC) Who Were Stable or Responding after at Least Four Cycles of Platinum-Based Chemotherapy: North Central Cancer Treatment Group (Alliance) N0923 Study

(2019) Erin L. Schenk et al.   Journal of Thoracic Oncology

Rhabdoviruses as vaccine platforms for infectious disease and cancer

(2018) Franz Zemp et al.   Biotechnology & Genetic Engineering Reviews

Phase I study of oncolytic vaccinia virus GL-ONC1 in patients with peritoneal carcinomatosis

(2018) Ulrich M. Lauer et al.   CLINICAL CANCER RESEARCH

A Randomized Phase II Study of FOLFOX6/Bevacizumab With or Without Pelareorep in Patients With Metastatic Colorectal Cancer: IND.210, a Canadian Cancer Trials Group Trial

(2018) Derek J. Jonker et al.   Clinical Colorectal Cancer

Oncorine, the World First Oncolytic Virus Medicine and its Update in China

(2018) Min Liang   CURRENT CANCER DRUG TARGETS

Coxsackievirus B1 infections are associated with the initiation of insulin-driven autoimmunity that progresses to type 1 diabetes

(2018) Amir-Babak Sioofy-Khojine et al.   DIABETOLOGIA

Unleashing the therapeutic potential of oncolytic viruses

(2018) Praveen K. Bommareddy et al.   JOURNAL OF CLINICAL INVESTIGATION

Phase II trial of pexa-vec (pexastimogene devacirepvec; JX-594), an oncolytic and immunotherapeutic vaccinia virus, in patients with metastatic, refractory renal cell carcinoma (RCC).

(2018) Seong-Geun Kim et al.   JOURNAL OF CLINICAL ONCOLOGY

Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma

(2018) Jason Chesney et al.   JOURNAL OF CLINICAL ONCOLOGY

The Immune System in Oncolytic Immunovirotherapy: Gospel, Schism and Heresy

(2018) Richard G. Vile   MOLECULAR THERAPY

Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy

(2018) Jacob M. Ricca et al.   MOLECULAR THERAPY

Recurrent Glioblastoma Treated with Recombinant Poliovirus

(2018) Annick Desjardins et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oncotargeting by Vesicular Stomatitis Virus (VSV): Advances in Cancer Therapy

(2018) Suman Bishnoi et al.   Viruses-Basel

Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference

(2018) Arthur Dyer et al.   CANCER GENE THERAPY

Abstract CT072: First in human (FIH) dose escalation studies of intravenous administration of VSV-IFNβ-NIS (Voyager-V1™) in Stage IV or recurrent endometrial cancer

(2018) Jamie Bakkum-Gamez et al.   CANCER RESEARCH

The advent of oncolytic virotherapy in oncology: The Rigvir® story

(2018) Pēteris Alberts et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials

(2018) Jonathan G. Pol et al.   OncoImmunology

The Current Status and Future Prospects of Oncolytic Viruses in Clinical Trials against Melanoma, Glioma, Pancreatic, and Breast Cancers

(2018) Ibrahim Eissa et al.   Cancers

Oncolytic herpes simplex virus and immunotherapy

(2018) Wenqing Ma et al.   BMC IMMUNOLOGY

Abscopal Effect in Non-injected Tumors Achieved with Cytokine-Armed Oncolytic Adenovirus

(2018) Riikka Havunen et al.   Molecular Therapy-Oncolytics

Strategy to detect pre-existing immunity to AAV gene therapy

(2017) L Falese et al.   GENE THERAPY

Recent advances in vesicular stomatitis virus-based oncolytic virotherapy: a 5-year update

(2017) Sébastien A. Felt et al.   JOURNAL OF GENERAL VIROLOGY

Phase I trial of systemic administration of Edmonston strain of measles virus genetically engineered to express the sodium iodide symporter in patients with recurrent or refractory multiple myeloma

(2017) A Dispenzieri et al.   LEUKEMIA

Biomarkers of prostate cancer sensitivity to the Sendai virus

(2017) A. A. Belova et al.   MOLECULAR BIOLOGY

Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial

(2017) Karsten Geletneky et al.   MOLECULAR THERAPY

Phase I Trial of DNX-2401 for Diffuse Intrinsic Pontine Glioma Newly Diagnosed in Pediatric Patients

(2017) Sonia Tejada et al.   NEUROSURGERY

Efficacy of recombinant human adenovirus-p53 combined with chemotherapy for locally advanced cervical cancer: A clinical trial

(2017) Jie Xiao et al.   Oncology Letters

Oncolytic Recombinant Vesicular Stomatitis Virus (VSV) Is Nonpathogenic and Nontransmissible in Pigs, a Natural Host of VSV

(2017) Lauro Velazquez-Salinas et al.   Human Gene Therapy Clinical Development

Genetically Engineered Vaccinia Viruses As Agents for Cancer Treatment, Imaging, and Transgene Delivery

(2017) Dana Haddad   Frontiers in Oncology

Talimogene Laherparepvec (T-VEC) and Other Oncolytic Viruses for the Treatment of Melanoma

(2016) Praveen K. Bommareddy et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Cancer immunotherapy: the beginning of the end of cancer?

(2016) Sofia Farkona et al.   BMC Medicine

The Efficacy of Oncolytic Adenovirus Is Mediated by T-cell Responses against Virus and Tumor in Syrian Hamster Model

(2016) Xiaozhu Li et al.   CLINICAL CANCER RESEARCH

Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer

(2016) Adel Samson et al.   GUT

Cutaneous head and neck melanoma in OPTiM, a randomized phase 3 trial of talimogene laherparepvec versus granulocyte-macrophage colony-stimulating factor for the treatment of unresected stage IIIB/IIIC/IV melanoma

(2016) Robert H. I. Andtbacka et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Phase 1 Study of Intravenous Oncolytic Poxvirus (vvDD) in Patients With Advanced Solid Cancers

(2016) Stephanie Downs-Canner et al.   MOLECULAR THERAPY

Development of immuno-oncology drugs — from CTLA4 to PD1 to the next generations

(2016) Axel Hoos   NATURE REVIEWS DRUG DISCOVERY

Differential expression of TYRP1 in adult human retinal pigment epithelium and uveal melanoma cells

(2016) CHUN QIU et al.   Oncology Letters

Recombinant oncolytic poliovirus, PVSRIPO, has potent cytotoxic and innate inflammatory effects, mediating therapy in human breast and prostate cancer xenograft models

(2016) Eda K. Holl et al.   Oncotarget

Intratumoral immunotherapy for melanoma

(2015) Manisha Singh et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Arming oncolytic viruses to leverage antitumor immunity

(2015) Tanja D de Gruijl et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Vaccinia virus, a promising new therapeutic agent for pancreatic cancer

(2015) Chadwan Al Yaghchi et al.   Immunotherapy

Immunogenic cell death

(2015) Abhishek D. Garg et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma

(2015) Robert H.I. Andtbacka et al.   JOURNAL OF CLINICAL ONCOLOGY

Adapted ECHO-7 virus Rigvir immunotherapy (oncolytic virotherapy) prolongs survival in melanoma patients after surgical excision of the tumour in a retrospective study

(2015) Simona Doniņa et al.   MELANOMA RESEARCH

First-in-man Study of Western Reserve Strain Oncolytic Vaccinia Virus: Safety, Systemic Spread, and Antitumor Activity

(2015) Herbert J Zeh et al.   MOLECULAR THERAPY

Efficacy of recombinant adenoviral human p53 gene in the treatment of lung cancer-mediated pleural effusion

(2015) KUN-LIN LI et al.   Oncology Letters

Immunological data from cancer patients treated with Ad5/3 E2F Δ24 GMCSF suggests utility for tumor immunotherapy

(2015) Otto Hemminki et al.   Oncotarget

Oncolytic viruses: perspectives on clinical development

(2015) James Burke et al.   Current Opinion in Virology

Oncolysis by paramyxoviruses: preclinical and clinical studies

(2015) Olga V Matveeva et al.   Molecular Therapy-Oncolytics

Selective intra-arterial infusion of rAd-p53 with chemotherapy for advanced oral cancer: a randomized clinical trial

(2014) Yi Li et al.   BMC Medicine

Oncolytic Measles Virus Expressing the Sodium Iodide Symporter to Treat Drug-Resistant Ovarian Cancer

(2014) E. Galanis et al.   CANCER RESEARCH

Utilizing adenovirus vectors for gene delivery in cancer

(2014) Dayananda Kasala et al.   Expert Opinion on Drug Delivery

Sensitivity of the Polymerase of Vesicular Stomatitis Virus to 2′ Substitutions in the Template and Nucleotide Triphosphate during Initiation and Elongation

(2014) Benjamin Morin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vesiculovirus Neutralization by Natural IgM and Complement

(2014) M. Z. Tesfay et al.   JOURNAL OF VIROLOGY

Gene therapy for unresectable hepatocellular carcinoma using recombinant human adenovirus type 5

(2014) Jun Dong et al.   MEDICAL ONCOLOGY

The Profile of Tumor Antigens Which Can be Targeted by Immunotherapy Depends Upon the Tumor's Anatomical Site

(2014) Vanesa Alonso-Camino et al.   MOLECULAR THERAPY

TG1042 (Adenovirus-interferon-γ) in Primary Cutaneous B-cell Lymphomas: A Phase II Clinical Trial

(2014) Brigitte Dreno et al.   PLoS One

Pre-existing immunity against Ad vectors

(2014) Hugues Fausther-Bovendo et al.   Human Vaccines & Immunotherapeutics

Neutralizing antibody responses to enterovirus and adenovirus in healthy adults in China

(2014) Xiang Wang et al.   Emerging Microbes & Infections

Viral therapy for pancreatic cancer: Tackle the bad guys with poison

(2013) Can Xu et al.   CANCER LETTERS

Oncolytic Vaccinia Virus Disrupts Tumor-Associated Vasculature in Humans

(2013) C. J. Breitbach et al.   CANCER RESEARCH

Autologous tumor cell vaccines for post-operative active-specific immunotherapy of colorectal carcinoma: long-term patient survival and mechanism of function

(2013) Volker Schirrmacher et al.   Expert Review of Vaccines

Serotype chimeric oncolytic adenovirus coding for GM-CSF for treatment of sarcoma in rodents and humans

(2013) Simona Bramante et al.   INTERNATIONAL JOURNAL OF CANCER

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial

(2013) Manfred Westphal et al.   LANCET ONCOLOGY

Granulocyte–macrophage colony-stimulating factor: not just another haematopoietic growth factor

(2013) Alejandro Francisco-Cruz et al.   MEDICAL ONCOLOGY

Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer

(2013) Jeong Heo et al.   NATURE MEDICINE

Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies

(2012) E. M. Karapanagiotou et al.   CLINICAL CANCER RESEARCH

Oncolytic virotherapy with modified adenoviruses and novel therapeutic targets

(2012) Gunnel Halldén et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Oncolytic Newcastle disease virus for cancer therapy: old challenges and new directions

(2012) Dmitriy Zamarin et al.   Future Microbiology

Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy

(2012) V Roulstone et al.   GENE THERAPY

Oncolytic enteroviruses

(2012) P. M. Chumakov et al.   MOLECULAR BIOLOGY

Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma

(2012) Jose Pulido et al.   NATURE BIOTECHNOLOGY

ViralZone: recent updates to the virus knowledge resource

(2012) Patrick Masson et al.   NUCLEIC ACIDS RESEARCH

Critical phosphoprotein elements that regulate polymerase architecture and function in vesicular stomatitis virus

(2012) A. A. Rahmeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical research on recombinant human Ad-p53 injection combined with cisplatin in treatment of malignant pleural effusion induced by lung cancer

(2012) Wei-Zhu Zhao et al.   Chinese Journal of Cancer

Hypoxia enhances the replication of oncolytic herpes simplex virus in p53- breast cancer cells

(2011) Michael Fasullo et al.   CELL CYCLE

Recombinant Vesicular Stomatitis Virus–Based Vaccines Against Ebola and Marburg Virus Infections

(2011) Thomas W. Geisbert et al.   JOURNAL OF INFECTIOUS DISEASES

Targeting Tumor Vasculature With an Oncolytic Virus

(2011) Caroline J Breitbach et al.   MOLECULAR THERAPY

Construction of an Oncolytic Herpes Simplex Virus That Precisely Targets Hepatocellular Carcinoma Cells

(2011) Xinping Fu et al.   MOLECULAR THERAPY

Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and A18

(2011) Gough G Au et al.   Virology Journal

Type III IFN Interleukin-28 Mediates the Antitumor Efficacy of Oncolytic Virus VSV in Immune-Competent Mouse Models of Cancer

(2010) Phonphimon Wongthida et al.   CANCER RESEARCH

Oncolytic Viral Therapy for Prostate Cancer: Efficacy of Reovirus as a Biological Therapeutic

(2010) C. M. Thirukkumaran et al.   CANCER RESEARCH

Phase I Trial of Intraperitoneal Administration of an Oncolytic Measles Virus Strain Engineered to Express Carcinoembryonic Antigen for Recurrent Ovarian Cancer

(2010) E. Galanis et al.   CANCER RESEARCH

A Phase I Study of the Combination of Intravenous Reovirus Type 3 Dearing and Gemcitabine in Patients with Advanced Cancer

(2010) M. P. Lolkema et al.   CLINICAL CANCER RESEARCH

Therapeutic Potential of Oncolytic Measles Virus: Promises and Challenges

(2010) E Galanis   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical trials with oncolytic reovirus: Moving beyond phase I into combinations with standard therapeutics

(2010) K.J. Harrington et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Oncolytic parvoviruses as cancer therapeutics

(2010) Jean Rommelaere et al.   CYTOKINE & GROWTH FACTOR REVIEWS

MAGE A3 antigen-specific cancer immunotherapeutic

(2010) Nir Peled et al.   Immunotherapy

New perspectives in cancer virotherapy: bringing the immune system into play

(2010) Nicolas Boisgerault et al.   Immunotherapy

Enhancement of NK cell antitumor responses using an oncolytic parvovirus

(2010) Rauf Bhat et al.   INTERNATIONAL JOURNAL OF CANCER

Adaptive Antiviral Immunity Is a Determinant of the Therapeutic Success of Oncolytic Virotherapy

(2010) Paul T Sobol et al.   MOLECULAR THERAPY

Delivering nanomedicine to solid tumors

(2010) Rakesh K. Jain et al.   Nature Reviews Clinical Oncology

Herpesvirus systematics

(2010) Andrew J. Davison   VETERINARY MICROBIOLOGY

Expression of IFN-  Enhances Both Efficacy and Safety of Oncolytic Vesicular Stomatitis Virus for Therapy of Mesothelioma

(2009) C. L. Willmon et al.   CANCER RESEARCH

Clinical study of recombinant adenovirus-p53 combined with fractionated stereotactic radiotherapy for hepatocellular carcinoma

(2009) Zhi-xiang Yang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Activated Ras/MEK Inhibits the Antiviral Response of Alpha Interferon by Reducing STAT2 Levels

(2009) S. L. Christian et al.   JOURNAL OF VIROLOGY

Some Attenuated Variants of Vesicular Stomatitis Virus Show Enhanced Oncolytic Activity against Human Glioblastoma Cells relative to Normal Brain Cells

(2009) G. Wollmann et al.   JOURNAL OF VIROLOGY

Noninvasive Imaging and Radiovirotherapy of Prostate Cancer Using an Oncolytic Measles Virus Expressing the Sodium Iodide Symporter

(2009) Pavlos Msaouel et al.   MOLECULAR THERAPY

Engineered Newcastle Disease Virus as an Improved Oncolytic Agent Against Hepatocellular Carcinoma

(2009) Jennifer Altomonte et al.   MOLECULAR THERAPY

Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity

(2008) R. J. Prestwich et al.   CLINICAL CANCER RESEARCH

Measles Virus as An Oncolytic Vector Platform

(2008) Boris Blechacz et al.   CURRENT GENE THERAPY

Efficacy and Safety of the Oncolytic Herpes Simplex Virus rRp450 Alone and Combined With Cyclophosphamide

(2008) Mark A Currier et al.   MOLECULAR THERAPY

The Targeted Oncolytic Poxvirus JX-594 Demonstrates Antitumoral, Antivascular, and Anti-HBV Activities in Patients With Hepatocellular Carcinoma

(2008) Ta-Chiang Liu et al.   MOLECULAR THERAPY