Autologous tumor cell vaccines for post-operative active-specific immunotherapy of colorectal carcinoma: long-term patient survival and mechanism of function

Synergistic Stimulation of Antigen Presenting Cells via TLR by Combining CpG ODN and Poly(γ-glutamic acid)-Based Nanoparticles as Vaccine Adjuvants

(2013) Fumiaki Shima et al.   BIOCONJUGATE CHEMISTRY

Exploiting CTLA-4, PD-1 and PD-L1 to reactivate the host immune response against cancer

(2013) S A Quezada et al.   BRITISH JOURNAL OF CANCER

Specific Elimination of CD133+ Tumor Cells with Targeted Oncolytic Measles Virus

(2013) P. Bach et al.   CANCER RESEARCH

Direct effect of dsRNA mimetics on cancer cells induces endogenous IFN-β production capable of improving dendritic cell function

(2013) Gerardo Gatti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T-helper-1-cell cytokines drive cancer into senescence

(2013) Heidi Braumüller et al.   NATURE

T-Bet and Eomes Regulate the Balance between the Effector/Central Memory T Cells versus Memory Stem Like T Cells

(2013) Gang Li et al.   PLoS One

IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors

(2012) N. Cieri et al.   BLOOD

Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4 memory T cells

(2012) Yasuhiro Nemoto et al.   GUT

Neutrophils Transport Antigen from the Dermis to the Bone Marrow, Initiating a Source of Memory CD8+ T Cells

(2012) Darragh Duffy et al.   IMMUNITY

Mesenchymal stem cells promote neutrophil activation by inducing IL-17 production in CD4+ CD45RO+ T cells

(2012) Shu-Ching Hsu et al.   IMMUNOBIOLOGY

The evolving concept of cancer and metastasis stem cells

(2012) Irène Baccelli et al.   JOURNAL OF CELL BIOLOGY

IL-15-Dependent Upregulation of GITR on CD8 Memory Phenotype T Cells in the Bone Marrow Relative to Spleen and Lymph Node Suggests the Bone Marrow as a Site of Superior Bioavailability of IL-15

(2012) L. M. Snell et al.   JOURNAL OF IMMUNOLOGY

Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer

(2012) Suzanne L. Topalian et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preventive Cancer Stem Cell-Based Vaccination Reduces Liver Metastasis Development in a Rat Colon Carcinoma Syngeneic Model

(2012) Sonia Duarte et al.   STEM CELLS

Clinical Effects of Adjuvant Active Specific Immunotherapy Differ between Patients with Microsatellite-Stable and Microsatellite-Instable Colon Cancer

(2011) V. A. de Weger et al.   CLINICAL CANCER RESEARCH

Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection

(2011) Linda M. Wakim et al.   NATURE

Exploiting the Role of Endogenous Lymphoid-Resident Dendritic Cells in the Priming of NKT Cells and CD8+ T Cells to Dendritic Cell-Based Vaccines

(2011) Troels R. Petersen et al.   PLoS One

Early expression of stem cell-associated genes within the CD8 compartment after treatment with a tumor vaccine

(2010) M. Eric Kohler et al.   CELLULAR IMMUNOLOGY

Danger signals in tumor cells: a risk factor for autoimmune disease?

(2010) Volker Schirrmacher et al.   Expert Review of Vaccines

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction

(2010) N. R. Blatner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High frequencies of less differentiated and more proliferative WT1-specific CD8+ T cells in bone marrow in tumor-bearing patients: An important role of bone marrow as a secondary lymphoid organ

(2009) Ayako Murao et al.   CANCER SCIENCE

Human Bone Marrow as a Source to Generate CMV-specific CD4+ T Cells With Multifunctional Capacity

(2009) Il-Kang Na et al.   JOURNAL OF IMMUNOTHERAPY

Activation of Natural Killer Cells by Newcastle Disease Virus Hemagglutinin-Neuraminidase

(2009) M. Jarahian et al.   JOURNAL OF VIROLOGY

Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo

(2009) Yu-gang Wu et al.   MEDICAL ONCOLOGY

Molecular Basis of Colorectal Cancer

(2009) Sanford D. Markowitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Detection and Functional Analysis of Tumor Infiltrating T-Lymphocytes (TIL) in Liver Metastases from Colorectal Cancer

(2008) Philipp Wagner et al.   ANNALS OF SURGICAL ONCOLOGY

Efficiency of adjuvant active specific immunization with Newcastle disease virus modified tumor cells in colorectal cancer patients following resection of liver metastases: results of a prospective randomized trial

(2008) T. Schulze et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Randomized clinical studies of anti-tumor vaccination: state of the art in 2008

(2008) Philippe Fournier et al.   Expert Review of Vaccines

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

(2008) Paul Salama et al.   JOURNAL OF CLINICAL ONCOLOGY