Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy

Epithelial-mesenchymal transition leads to NK cell–mediated metastasis-specific immunosurveillance in lung cancer

(2018) Peter J. Chockley et al.   JOURNAL OF CLINICAL INVESTIGATION

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma

(2018) Frederick F. Lang et al.   JOURNAL OF CLINICAL ONCOLOGY

Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy

(2018) Jacob M. Ricca et al.   MOLECULAR THERAPY

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells

(2017) Hong-Sheng Dai et al.   IMMUNITY

Anti-EGFR Targeted Monoclonal Antibody Isotype Influences Antitumor Cellular Immunity in Head and Neck Cancer Patients

(2016) S. Trivedi et al.   CLINICAL CANCER RESEARCH

Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy

(2016) S. J. Blake et al.   Cancer Discovery

Exclusion of T Cells From Pancreatic Carcinomas in Mice Is Regulated by Ly6Clow F4/80+ Extratumoral Macrophages

(2015) Gregory L. Beatty et al.   GASTROENTEROLOGY

Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy

(2015) Giuseppe Di Caro et al.   GUT

Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma

(2015) Robert H.I. Andtbacka et al.   JOURNAL OF CLINICAL ONCOLOGY

Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses

(2015) Norman Woller et al.   MOLECULAR THERAPY

Going viral: a review of replication-selective oncolytic adenoviruses

(2015) Christopher Larson et al.   Oncotarget

PolySia-Specific Retargeting of Oncolytic Viruses Triggers Tumor-Specific Immune Responses and Facilitates Therapy of Disseminated Lung Cancer

(2015) A. Kloos et al.   Cancer Immunology Research

Adenovirus-Based Vaccines for Fighting Infectious Diseases and Cancer: Progress in the Field

(2014) Dragomira Majhen et al.   HUMAN GENE THERAPY

Myeloid-Derived Suppressor Activity Is Mediated by Monocytic Lineages Maintained by Continuous Inhibition of Extrinsic and Intrinsic Death Pathways

(2014) Jessica M. Haverkamp et al.   IMMUNITY

CTLA-4 and PD-L1 Checkpoint Blockade Enhances Oncolytic Measles Virus Therapy

(2014) Christine E Engeland et al.   MOLECULAR THERAPY

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Localized Oncolytic Virotherapy Overcomes Systemic Tumor Resistance to Immune Checkpoint Blockade Immunotherapy

(2014) D. Zamarin et al.   Science Translational Medicine

Cetuximab-Activated Natural Killer and Dendritic Cells Collaborate to Trigger Tumor Antigen-Specific T-cell Immunity in Head and Neck Cancer Patients

(2013) R. M. Srivastava et al.   CLINICAL CANCER RESEARCH

Nivolumab plus Ipilimumab in Advanced Melanoma

(2013) Jedd D. Wolchok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oncolytic and Immunotherapeutic Vaccinia Induces Antibody-Mediated Complement-Dependent Cancer Cell Lysis in Humans

(2013) M. K. Kim et al.   Science Translational Medicine

Exploiting the Mutanome for Tumor Vaccination

(2012) J. C. Castle et al.   CANCER RESEARCH

Polysialyltransferase: A New Target in Metastatic Cancer

(2012) R .A. Falconer et al.   CURRENT CANCER DRUG TARGETS

Fc RIIb on Liver Sinusoidal Endothelium Clears Small Immune Complexes

(2012) L. P. Ganesan et al.   JOURNAL OF IMMUNOLOGY

NK Cells Regulate CD8+ T Cell Priming and Dendritic Cell Migration during Influenza A Infection by IFN-  and Perforin-Dependent Mechanisms

(2012) M. Q. Ge et al.   JOURNAL OF IMMUNOLOGY

Oncolytic virotherapy

(2012) Stephen J Russell et al.   NATURE BIOTECHNOLOGY

ExPASy: SIB bioinformatics resource portal

(2012) P. Artimo et al.   NUCLEIC ACIDS RESEARCH

Antibody-Dependent Cell Cytotoxicity Synapses Form in Mice during Tumor-Specific Antibody Immunotherapy

(2011) P. Hubert et al.   CANCER RESEARCH

Adenoviral Vector Immunity: Its Implications and Circumvention Strategies

(2011) Yadvinder S. Ahi et al.   CURRENT GENE THERAPY

Adenovirus Serotype 5 Neutralizing Antibodies Target both Hexon and Fiber following Vaccination and Natural Infection

(2011) R. R. Bradley et al.   JOURNAL OF VIROLOGY

Adenovirus Serotype 5-Specific Neutralizing Antibodies Target Multiple Hexon Hypervariable Regions

(2011) R. R. Bradley et al.   JOURNAL OF VIROLOGY

Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation

(2010) Fabian Benencia et al.   CANCER BIOLOGY & THERAPY

Absence of mouse 2B4 promotes NK cell–mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis

(2010) Stephen N. Waggoner et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Oncolytic Viruses for Cancer Therapy: Overcoming the Obstacles

(2010) Han Hsi Wong et al.   Viruses-Basel

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF

(2009) Luigi Dolcetti et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phase II Clinical Trial of a Granulocyte-Macrophage Colony-Stimulating Factor–Encoding, Second-Generation Oncolytic Herpesvirus in Patients With Unresectable Metastatic Melanoma

(2009) Neil N. Senzer et al.   JOURNAL OF CLINICAL ONCOLOGY

Adenovirus type 5 with modified hexons induces robust transgene-specific immune responses in mice with pre-existing immunity against adenovirus type 5

(2009) Shinya Abe et al.   JOURNAL OF GENE MEDICINE

Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma

(2008) F Errington et al.   GENE THERAPY

Effect of Preexisting Immunity on Oncolytic Adenovirus Vector INGN 007 Antitumor Efficacy in Immunocompetent and Immunosuppressed Syrian Hamsters

(2008) D. Dhar et al.   JOURNAL OF VIROLOGY

Clearance of Adenovirus by Kupffer Cells Is Mediated by Scavenger Receptors, Natural Antibodies, and Complement

(2008) Z. Xu et al.   JOURNAL OF VIROLOGY

Immunosuppression Enhances Oncolytic Adenovirus Replication and Antitumor Efficacy in the Syrian Hamster Model

(2008) Maria A Thomas et al.   MOLECULAR THERAPY