Aristolochic acid induces mitochondrial apoptosis through oxidative stress in rats, leading to liver damage

c-Jun Amino Terminal Kinase Signaling Promotes Aristolochic Acid-Induced Acute Kidney Injury

(2021) Fan Yang et al.   Frontiers in Physiology

Roles of selenoprotein S in reactive oxygen species-dependent neutrophil extracellular trap formation induced by selenium-deficient arteritis

(2021) Qianru Chi et al.   Redox Biology

Endoplasmic Reticulum Stress Signaling in Cancer Cells

(2020) Scott A. Oakes   AMERICAN JOURNAL OF PATHOLOGY

Aristolochic Acid-Induced Nephrotoxicity: Molecular Mechanisms and Potential Protective Approaches

(2020) Etienne Empweb Anger et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The protective effects of Terminalia laxiflora extract on hepato-nephrotoxicity induced by fipronil in male rats

(2020) A. A. Khalaf et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Florfenicol causes excessive lipid peroxidation and apoptosis induced renal injury in broilers

(2020) Xiao Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Mitophagy–lysosomal pathway is involved in silver nanoparticle-induced apoptosis in A549 cells

(2020) Jiangyan Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Chemotaxonomy of the ethnic antidote Aristolochia indica for aristolochic acid content: Implications of anti-phospholipase activity and genotoxicity study

(2020) Abhijit Dey et al.   JOURNAL OF ETHNOPHARMACOLOGY

Regulation of H2S-induced necroptosis and inflammation in broiler bursa of Fabricius by the miR-15b-5p/TGFBR3 axis and the involvement of oxidative stress in this process

(2020) Chi Qianru et al.   JOURNAL OF HAZARDOUS MATERIALS

Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

(2019) Rumani Singh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection

(2019) Hai Hu et al.   Frontiers in Immunology

A new dual-spectroscopic strategy for the direct detection of aristolochic acids in blood and tissue

(2019) Lei Ouyang et al.   ANALYTICAL CHEMISTRY

Systematic Overview of Aristolochic Acids: Nephrotoxicity, Carcinogenicity, and Underlying Mechanisms

(2019) Jiayin Han et al.   Frontiers in Pharmacology

Zoledronic acid prevents the hepatic changes associated with high fat diet in rats; the potential role of mevalonic acid pathway in nonalcoholic steatohepatitis

(2019) Reham Hussein Mohamed et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The ameliorations of Ganoderma applanatum residue polysaccharides against CCl4 induced liver injury

(2019) Zheng Gao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antidiabetic and hypolipidemic efficacy of skin and seed extracts of Momordica cymbalaria on alloxan induced diabetic model in rats

(2019) Abbirami Elangovan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chinese Herbal Formula (CHF03) Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) Through Inhibiting Lipogenesis and Anti-Oxidation Mechanisms

(2019) Yizhe Cui et al.   Frontiers in Pharmacology

Assessment of nephrotoxicity of herbal medicine containing aristolochic acid in mice

(2019) Yi Quan et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Atmospheric H2S triggers immune damage by activating the TLR-7/MyD88/NF-κB pathway and NLRP3 inflammasome in broiler thymus

(2019) Xueyuan Hu et al.   CHEMOSPHERE

Apoptosis and necroptosis in the liver: a matter of life and death

(2018) Robert F. Schwabe et al.   Nature Reviews Gastroenterology & Hepatology

Inhibitory Effect of Astaxanthin on Oxidative Stress-Induced Mitochondrial Dysfunction-A Mini-Review

(2018) Suhn Kim et al.   Nutrients

Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia

(2017) Alvin W. T. Ng et al.   Science Translational Medicine

The effects of rotenone-induced toxicity via the NF-κB–iNOS pathway in rat liver

(2017) Xiaowen Jiang et al.   TOXICOLOGY MECHANISMS AND METHODS

The effects of rotenone-induced toxicity via the NF-κB–iNOS pathway in rat liver

(2017) Xiaowen Jiang et al.   TOXICOLOGY MECHANISMS AND METHODS

Preventing Aristolochic Acid Nephropathy

(2015) N. Anandagoda et al.   Clinical Journal of the American Society of Nephrology

Aristolochic acid-induced apoptosis and G2 cell cycle arrest depends on ROS generation and MAP kinases activation

(2014) Victor Romanov et al.   ARCHIVES OF TOXICOLOGY

Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis

(2013) Krishnendu Sinha et al.   ARCHIVES OF TOXICOLOGY

Regulation of the Intrinsic Apoptosis Pathway by Reactive Oxygen Species

(2012) Chu-Chiao Wu et al.   ANTIOXIDANTS & REDOX SIGNALING

Aristolochic acid-induced accumulation of methylglyoxal and Nε-(carboxymethyl)lysine: An important and novel pathway in the pathogenic mechanism for aristolochic acid nephropathy

(2012) Yi-Chieh Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Developmental nephrotoxicity of aristolochic acid in a zebrafish model

(2012) Yu-Ju Ding et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

(2011) Jean-Claude Martinou et al.   DEVELOPMENTAL CELL

Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy

(2011) Qian Huang et al.   NATURE MEDICINE

Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX

(2010) Bonsu Ku et al.   CELL RESEARCH

The BCL-2 Family Reunion

(2010) Jerry E. Chipuk et al.   MOLECULAR CELL