Subacute cadmium exposure promotes M1 macrophage polarization through oxidative stress-evoked inflammatory response and induces porcine adrenal fibrosis

Transcriptome sequencing reveals genes involved in cadmium-triggered oxidative stress in the chicken heart

(2021) Chunlin Yu et al.   POULTRY SCIENCE

Cadmium induced skeletal underdevelopment, liver cell apoptosis and hepatic energy metabolism disorder in Bufo gargarizans larvae by disrupting thyroid hormone signaling

(2021) Jing Ya et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Cadmium induced inflammation and apoptosis of porcine epididymis via activating RAF1/MEK/ERK and NF-κB pathways

(2021) Yue Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Immunophenotypical Characterization of M1/M2 Macrophages and Lymphocytes in Cisplatin-Induced Rat Progressive Renal Fibrosis

(2021) Minto Nakagawa et al.   Cells

Activation of AMPK Promotes Maturation of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2021) Liang Ye et al.   Frontiers in Cell and Developmental Biology

Cadmium induces the thymus apoptosis of pigs through ROS-dependent PTEN/PI3K/AKT signaling pathway

(2021) Zhang Yiming et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

AMP-activated protein kinase: A remarkable contributor to preserve a healthy heart against ROS injury

(2021) Alice Marino et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cadmium exposure induces TNF-α-mediated necroptosis via FPR2/TGF-β/NF-κB pathway in swine myocardium

(2021) Xia Zhao et al.   TOXICOLOGY

NLRP3 inflammasome mediated pyroptosis is involved in cadmium exposure-induced neuroinflammation through the IL-1β/IkB-α-NF-κB-NLRP3 feedback loop in swine

(2021) Jingzeng Cai et al.   TOXICOLOGY

AMPK-deficiency forces metformin-challenged cancer cells to switch from carbohydrate metabolism to ketogenesis to support energy metabolism

(2021) Flavio R. Palma et al.   ONCOGENE

New insights into crosstalk between apoptosis and necroptosis co-induced by chlorothalonil and imidacloprid in Ctenopharyngodon idellus kidney cells

(2021) Xiaojing Li et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cadmium induces endoplasmic reticulum stress-mediated apoptosis in pig pancreas via the increase of Th1 cells

(2021) Hao Wu et al.   TOXICOLOGY

Oleic acid protects against cadmium induced cardiac and hepatic tissue injury in male Wistar rats: A mechanistic study

(2020) Bharati Bhattacharjee et al.   LIFE SCIENCES

Cadmium exposure induces apoptosis, inflammation and immunosuppression through CYPs activation and antioxidant dysfunction in common carp neutrophils

(2020) Sun Jiaxin et al.   FISH & SHELLFISH IMMUNOLOGY

`Cadmium induced cardiac inflammation in chicken (Gallus gallus) via modulating cytochrome P450 systems and Nrf2 mediated antioxidant defense

(2020) Kai Guo et al.   CHEMOSPHERE

Health effects from contaminant exposure in Baltic Sea birds and marine mammals: A review

(2020) Christian Sonne et al.   ENVIRONMENT INTERNATIONAL

Macrophage polarization in innate immune responses contributing to pathogenesis of chronic kidney disease

(2020) Hewang Lee et al.   BMC Nephrology

Exposure to multiple heavy metals associate with aberrant immune homeostasis and inflammatory activation in preschool children

(2020) Yu Zhang et al.   CHEMOSPHERE

Cadmium exposure induces pyroptosis of lymphocytes in carp pronephros and spleens by activating NLRP3

(2020) Yiming Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Berberine attenuates severity of chronic pancreatitis and fibrosis via AMPK-mediated inhibition of TGF-β1/Smad signaling and M2 polarization

(2020) Sapana Bansod et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hydrogen Sulfide Alleviates Skeletal Muscle Fibrosis via Attenuating Inflammation and Oxidative Stress

(2020) Linlin Zhao et al.   Frontiers in Physiology

Antagonistic effect of N-acetyl-L-cysteine against cadmium-induced cytotoxicity and abnormal immune response on chicken peritoneal macrophages

(2020) Ding Zhang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

(2019) Yang Yang et al.   Cell Death & Disease

Macrophages: versatile players in renal inflammation and fibrosis

(2019) Patrick Ming-Kuen Tang et al.   Nature Reviews Nephrology

Rosmarinic Acid Attenuates Cadmium-Induced Nephrotoxicity via Inhibition of Oxidative Stress, Apoptosis, Inflammation and Fibrosis

(2019) Swarnalata Joardar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Protective Effects of Moderate Ca Supplementation against Cd-Induced Bone Damage under Different Population-Relevant Doses in Young Female Rats

(2019) Huang et al.   Nutrients

High Levels of IL-18 and IFN-γ in Chronically Inflamed Tissue in Chronic Granulomatous Disease

(2019) Virginia Meda Spaccamela et al.   Frontiers in Immunology

Cadmium induces BNIP3-dependent autophagy in chicken spleen by modulating miR-33-AMPK axis

(2018) Menghao Chen et al.   CHEMOSPHERE

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The macrophage phenotype and inflammasome component NLRP3 contributes to nephrocalcinosis-related chronic kidney disease independent from IL-1–mediated tissue injury

(2018) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring

(2018) Patrick Ming-Kuen Tang et al.   KIDNEY INTERNATIONAL

A positive feedback loop between IL-1β, LPS and NEU1 may promote atherosclerosis by enhancing a pro-inflammatory state in monocytes and macrophages

(2018) Irina Sieve et al.   VASCULAR PHARMACOLOGY

Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent

(2018) Asmaa A. Alsousi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Biochemical and histopathological changes of subacute cadmium intoxication in male rats

(2017) Rasha M. Saleh et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Cadmium stimulates myofibroblast differentiation and mouse lung fibrosis

(2017) Xin Hu et al.   TOXICOLOGY

Relaxin abrogates renal interstitial fibrosis by regulating macrophage polarization via inhibition of Toll-like receptor 4 signaling

(2017) Lei Chen et al.   Oncotarget

Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice

(2017) Yuji Sogawa et al.   Scientific Reports

The Role of TLR4 in M1 Macrophage-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells

(2016) Jun Shi et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cadmium exposure to murine macrophages decreases their inflammatory responses and increases their oxidative stress

(2016) Yuanxiang Jin et al.   CHEMOSPHERE

Environmental Exposure to Cadmium: Health Risk Assessment and its Associations with Hypertension and Impaired Kidney Function

(2016) Haiyun Wu et al.   Scientific Reports

Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages

(2015) Joao Incio et al.   PLoS One

Fatty acid oxidation is dispensable for human macrophage IL-4-induced polarization

(2014) Dmitry Namgaladze et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Perspectives in Endocrine Toxicity of Heavy Metals—A Review

(2014) S. V. S. Rana   BIOLOGICAL TRACE ELEMENT RESEARCH

A Review of Molecular Events of Cadmium-Induced Carcinogenesis

(2014) Joe Luevano et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

Proteomic characterization of human proinflammatory M1 and anti-inflammatory M2 macrophages and their response toCandida albicans

(2014) Jose Antonio Reales-Calderón et al.   PROTEOMICS

Cadmium Selectively Induces MIP-2 and COX-2 Through PTEN-Mediated Akt Activation in RAW264.7 Cells

(2014) Yin-Yin Huang et al.   TOXICOLOGICAL SCIENCES

From Monocytes to M1/M2 Macrophages: Phenotypical vs. Functional Differentiation

(2014) Paola Italiani et al.   Frontiers in Immunology

Risk assessment of polychlorinated biphenyls and heavy metals in soils of an abandoned e-waste site in China

(2013) Quan Zhang et al.   ENVIRONMENTAL POLLUTION

Chronic Exposure to Cadmium Disrupts the Adrenal Gland Activity of the NewtTriturus carnifex(Amphibia, Urodela)

(2013) Flaminia Gay et al.   Biomed Research International

Mitochondrial gene expression, antioxidant responses, and histopathology after cadmium exposure

(2012) Simone Al Kaddissi et al.   ENVIRONMENTAL TOXICOLOGY

Review Series--Inflammation & Fibrosis * Introduction

(2012) S. C. Donnelly   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Transcriptional integration of mitochondrial biogenesis

(2012) Richard C. Scarpulla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis

(2011) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

(2010) Zhenggang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cadmium levels in Europe: implications for human health

(2009) Jilang Pan et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

A study of metal concentrations and metallothionein binding capacity in liver, kidney and brain tissues of three Arctic seal species

(2009) Christian Sonne et al.   SCIENCE OF THE TOTAL ENVIRONMENT